• Korean Journal of Biological Psychiatry
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• v.8 no.1
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• pp.167-174
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• 2001

A 54-year old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred to the Kosin University Gospel Hospital. On arrival at the emergency room, he had confused mentality with disorientation, memory impairment, hypomania, marked anxiety and hyperirritability. The change of neuromuscular activity such as ataxia, gait disturbance, tremor, shivering, myoclonus and epileptic seizures was also shown. In addition, the symptoms and signs of autonomic instability including diaphoresis, tachycardia, hypotension, fever and facial flushing were noticed. The above symptoms developed after the administration of sertraline successive to the discontinuation of fluoxetine without any washout period. The degree of severity seemed to be severe because he had epileptic seizures, fever and hypotension. He was recovered from the severe serotonin syndrome by the supportive symptomatic treatment with sodium valproate, clonazepam, lorazepam and cyproheptadine after cessation of the selective serotonin reuptake inhibitors during hospitalization. Therefore, this rare case of severe serotonin syndrome was reported and related literatures were also reviewed.

• The Journal of Internal Korean Medicine
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• v.40 no.1
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• pp.154-163
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• 2019

Objective: We report on the administration progression and adverse event of Er-Xian decoction for menopausal hot flushes. A hot flush is a rapid and intense heat-dissipation reaction that involves considerable sweating, enlargement of the peripheral blood vessels, and internal body heat. Er-Xian decoction is a prescription for treating menopausal hot flush symptoms in postmenopausal women. We report administration progression and adverse event of Er-Xian decoction for menopausal hot flush. Methods: We used the Menopause Rating Scale and Menopause-Specific Quality of Life questionnaire to evaluate the progression of hot flushes, and we conducted a literature review to determine the effective dosage of Er-Xian decoction. Result: In all cases, Facial hot flushes and evaluation variables were improved by the administration of EXD. However, in Case 1, a rise of liver function indexes which may be related to EXD administration was observed. Conclusion: Considering that menopausal flushing usually lasts for several years, The resluts are meaningful that the short-term administration of EXD led to improvement of symptoms. In order to further use EXD in the future, it will be necessary to conduct follow-up studies on the subject of safety verification, such as repeated dose toxicity studies.

• Journal of Yeungnam Medical Science
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• v.7 no.2
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• pp.151-158
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• 1990

We reviewed 30 cases of superior vena cava syndrome in adult patients who were seen at the Yeungnam University Hospital from January 1985 to June 1990. The results were as follows : 1. The male-to-female ratio was 6.5:1, and the most patients were in the age group between the sixth and seventh decades. 2. The most common symptoms were dyspnea (87%) and followed by cough (63%), facial swelling (63%) and chest pain (44%) and the physical signs were dilated neck vein (97%), facial edema (93%) and facial flushing (45%) in order of frequency. 3. The simple chest x-ray findings were superior mediastinal widening (90%), right hilar mass (77%) and pleural effusion (31%). 4. Diagnosis was made by history and physical examination (100%), chest C-T scan (100%), simple chest x-ray (97%), bronchoscopy with biopsy (40%) and so on. 5. 21 cases of patients were confirmed by histology : 14 cases (46%) of bronchogenic ca. 4 cases (14%) of lymphoma, 3 cases (10%) of metastic lung ca. Of bronchogenic ca. small cell ca was 7 cases (23%), squamous cell ca, 5 cases (17%), and unclassified ca was 2 cases (6%). 6. In response of treatment, the clinical improvement was achieved in 18 cases with radiotherapy alone. 1 case with chemotherapy only, and 6 cases with radio-chemotherapy.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.3
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• pp.228-236
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• 2009

Objectives : Acne, one of the most common disorders in dermatology clinic, is a chronic inflammatory disease which has the symptoms of comedones, papules, pustules, cysts, nodules and scars mainly on the face. Although some of pathologic findings are suggested, but the exact causes and mechanisms are not yet known in Western Medicine. Hwangryeonhaedok-Tang(HRHDT) is an antiinflammatory, antipyretic and detoxifying herb decoction. In this report, we would like to share our experience of acne treatment with HRHDT. Methods : We had treated several patients with acne, facial flushing and uprising febrile sensation on face using oral administration and external application of HRHDT. HRHDT is basically made up with Scutellariae Radix, Coptidis Rhizoma, Phellodendri Cortex and Gardeniae Fructus. In this trial, several other herbs were added according to the individual patient's accompanying symptoms. After the decoction of herbs in amount for 10 days, $Yogourmet^{(R)}$ Kefir Starter 10 g was added to the herbal solution that was then fermented in an incubator at $25^{\circ}C$ for 72 hours, and divided into 30 doses. Results : Photographies were taken before and after the treatment. The severities of acne were evaluated with these photos according to the Korean Acne Grading System(KAGS). As results, we observed dramatic clinical improvements and the decreases of KAGS grades after the average treatment period of 8 weeks. The medication was orally administered 3 times a day and the external treatment was applied average twice a week during the whole treatment period. Conclusions : From these results, HRHDT may be considered as a good prescription for the febrile and toxic type of acne patients.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.173-179
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• 2020

Objectives: This study aims to report a case of hot flush-type rosacea improved by oral administration of Baekho-tang. Methods : The patient visited our clinic due to hot flash symptom on April 16, 2020. Based on the symptoms of hating heat, bloating, sweating, and thirst, traditional medicine Baekho-tang was prescribed. Results : After 5 days of taking Baekho-tang, the symptom score of hot flush improved significantly from 8 to 3. About a week later, most of the symptoms, including hot flush, edema, and burning sensation almost disappeared. After treatment, the follow-up process was conducted for about a month, and it was confirmed that the flushing of the face did not recur and remained improved. Conclusions : After a week of Baekho-tang administration, hot flush, burning sensation, edema and other symptoms associated with rosacea improved overall.

• Korean Journal of Head & Neck Oncology
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• v.23 no.2
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• pp.142-146
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• 2007

Objectives and Backgrounds : After parotidectomy, some of patients complain gustatory sweating, facial flushing and discomfort in the same area. A series of these symptoms are supposed to be caused by the aberrant regeneration of the secretory parasympathetic fibers to sweat glands and blood vessels of the skin following parotidectomy. In this study, we want to compare the efficacy of thermography to the Minor's starch-iodine test for determining the presence of Frey's syndrome. Materials and Methods : 48 patients who underwent total or superficial parotidectomy from March 2002 to December 2004 were selected for this study. A subjective clinical questionnaire and the objective Minor's starchiodine test were performed to evaluate the incidence of this syndrome. Total 21 patients were confirmed as positive Frey's syndrome and infrared thermography was performed for them. Result : Frey's syndrome occurred in 21 patients(43.8%). The average temperature of parotidectomy site and normal opposite area were $27.65^{\circ}C\;and\;26.41^{\circ}C$ respectively. Thermography showed temperature difference in 20 patient(95.2%) and the difference of temperature was statistically significant above $1.0^{\circ}C$(p<0.001). The severity of symptoms were related with the difference of temperature(p<0.05). Conclusion : Thermography is useful, non-invasive, simple and quantifying method to diagnose Frey's syndrome. Additionally, this geographic diagnosis is available to show the accurate area for botulinum toxin injection.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.488-493
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• 2006

To make a objective diagnosis of Dam Hun(痰暈), we investigated the 63 patients with Dam Hun(痰暈) and 34 normal people as control group. we compared the thermal difference between Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Gwan-won(CV4 關元) and we compared the thermal difference of Yang-mun(ST21 梁門), Chun_chu(ST25 天樞), Su-do(ST28 水道), too. All 63 patients had dizziness and GI trouble. They had the symptom - fatigue, nausea vomitting, head heaviness, indigestion, cold limbs, headache, heart burn, constipation, diarrhea, anorexia. And some had edema, numbness, insomnia, palpitation, facial flushing, dysuria, ringing. Considering the average temparature of Chon-jung(CV17 ), Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 水道) between the patients group and the control group, the patients group were lower than the control group except for Chon-jung(CV17 ), Gwan-won(CV4 關元), but the statistical significance was not. Considering the thermal difference of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Gwan-won(CV4 關元), Yang-mun(ST21 梁門), Chun-chu(ST25 天樞), Su-do(ST28 氷道) between the patients group and the control group, the temparature deviation of Chon-jung(CV17 ) and Chung-wan(CV12 中脘), Chon-jung(CV17 ) and Yang-mun(ST21 梁門) was significant. We suggest that coldness of upper abdomen is significant in diagnosis of Dam Hun(痰暈).

• The Korean Journal of Pain
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• v.1 no.2
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• pp.164-170
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• 1988

Neurolysis of the celiac plexus is performed to relieve intractable pain caused by carcinoma of the stomach, liver and pancreas, and upper abdominal metastasis of tumors having more distant origins. It is also occasionally effective in controlling the pain of chronic pancreatitis. Alcohol celiac plexus blocks were done in 22 patients of whom 18 had intractable upper abdominal pain from cancer and 4 had pain from chronic pancreatitis. In most cases, an initial diagnostic block with 0.2 percent bupivacaine was followed by the therapeuntic block performed by injecting 50ml of 60 percent ethyl alcohol. Good to excellent pain relief occurred in 86 percent of patients. Duration of pain relief was from 4 months to 7 months in 55 percent of patients. Complications and side effects were infrequently seen but did include a 16 percent decrease of mean systolic arterial pressure and 16 cases of facial flushing. This block is remarkably safe as well as effective for the relief of upper abdominal pain from cancer origin.

• The Journal of Korean Obstetrics and Gynecology
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• v.30 no.3
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• pp.117-127
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• 2017

Objectives: This study has been conducted on public health purposes for people with Menopausal disorders in rural areas. Methods: From February, 2017 to June, 2017, we performed the Korean Medicine in the "Menopausal Disorder Overcoming Program" conducted by the department of Health service, Imsil-Gun bogun Hospital. Menopausal women who participated were treated with acupuncture, moxibustion, Jaeumganghwa-tang for 20 weeks. Of the 34 patients, 16 patients were excluded due to absence of treatment at least once. And 18 treatment outcomes were analyzed. Results: The KI results showed that the average score decreased in 7 out of 11 questions after treatment. The results of BDI, the mean scores of the 17 questions except the 4 questions of the 21 questions after the treatment decreased. 12, 16, and BDI total score were statistically significantly reduced before and after treatment. Conclusions: The results of the Korean Medicine treatment seemed to be effective in alleviating facial flushing, insomnia, depressive symptoms and other symptoms in menopausal disorders.

• The Korean Journal of Pain
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• v.32 no.3
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• pp.178-186
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• 2019

Background: Epidural steroid injections (ESIs) have been widely used in managing spinal pain. Dexamethasone has recently emerged as a useful drug in this setting, relative to particulate steroids, although the associated systemic effects have not been fully elucidated. This study aimed to investigate the incidences and types of systemic effects after fluoroscopically guided ESI with dexamethasone. Methods: This retrospective study included 888 ESIs with dexamethasone (fluoroscopically guided at the cervical and lumbosacral levels) performed on 825 patients during January to June 2017. Data regarding systemic effects were collected via telephone interviews using a standardized questionnaire at 2 weeks after the procedure. Data on patient demographic, clinical, and procedural characteristics were collected and analyzed to identify factors that were associated with systemic effects. All statistical analyses were performed using the chi-squared test. Results: Among the 825 patients, 40 patients (4.8%) experienced systemic effects during the 2-week follow-up period. The most common systemic effect was facial flushing (12 patients, 1.5%), which was followed by urticaria (7 patients, 0.8%) and insomnia (7 patients, 0.8%). A history of spine surgery was significantly associated with the occurrence of systemic effects (P = 0.036). Systemic effects were significantly more common for injections at the cervical level than at the lumbar level (P = 0.019). Conclusions: Approximately 4.8% of the patients who underwent ESI with dexamethasone experienced minor and transient systemic effects. These effects were more common in patients who had undergone a previous spine surgery or received a cervical ESI.