• Nuclear Medicine and Molecular Imaging
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• v.42 no.4
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• pp.292-300
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• 2008

Purpose: Our purpose was to evaluate F-18 FDG uptake in pulmonary lymphangitic carcinomatosis (PLC) according to CT findings and histology of lung cancer. Materials and Methods: Thirty-three lung cancer patients with PLC were enrolled in this retrospective study. All the patients had a CT-based diagnosis of PLC. Chest CT findings of PLC were classified on the basis of involvement of axial interstitium. We categorized the involvement of axial interstitium as group 1, and the involvement of peripheral interstitium only as group 2. Visual and semiquantitative analyses by F-18 FDG PET/CT were performed in the PLC lesions. At first, we analyzed the F-18 FDG uptake in the PLC by visual assessment. If abnormal uptake was seen in the PLC, we drew regions of interest in the PLC lesions to obtain the maximum SUVs (maxSUVs). Results: Of the 33 patients, 22 had abnormal F-18 FDG uptake in the visual assessment. There was no significant difference in the frequency of abnormal F-18 FDG uptake between group 1 and group 2 (p=0.17), although the frequency of group 1 tended to be higher than group 2 (15/19 (78.9%) in group 1, 7/14 (50.0%) in group 2). However, group 1 had a higher maxSUV than group 2 (p<0.01, group 1: $2.9{\pm}1.4$, group 2: $1.5{\pm}0.6$). There was no significant difference in the frequency of abnormal F-18 FDG uptake and maxSUV among the histology of the lung cancers. Conclusion: The involvement of axial interstitium in the PLC by lung cancer has a higher maxSUV than the involvement of only peripheral interstitium.

• Membrane Journal
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• v.26 no.6
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• pp.480-489
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• 2016

In this study, the PVdF/MGO composite nanofiber membranes (PMGs) introducing Iron oxide-Graphene oxide ($Fe_3O_4/GO$, Metallic graphene oxide; MGO) was prepared via electrospinng method and its arsenic removal characteristics were investigated. The thermal treatment was carried out to improve the mechanical strength of nanofiber membranes and then the results showed that of outstanding improvement effect. However, in case of PMGs, the decreasing tendency of mechanical strength was indicated as increasing MGO contents. From the results of pore-size analysis, it was confirmed that the porous structured membranes with 0.3 to $0.45{\mu}m$ were prepared. For the water treatment application, the water flux measurement was carried out. In particular, PMG2.0 sample showed about 70% improved water flux results ($153kg/m^2h$) compared to that of pure PVdF nanofiber membrane ($91kg/m^2h$) under the 0.3 bar condition. In addition, the PMGs have indicated the high removal rates of both As(III) and As(V) (up to 81% and 68%, respectively). Based on the adsorption isotherm analysis, the adsorption of As(III) and As(V) ions were both more suitable for the Freundlich. From all of results, it was concluded that PVdF/MGO composite nanofiber membranes could be utilized as a water treatment membrane and for the Arsenic removal applications.

• Biomedical Science Letters
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• v.5 no.1
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• pp.1-10
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• 1999

This study was attempted to generate a monoclonal antibody against human $\alpha$-fetoprotein (AFP) and to produce an immunoassay, recognizing AFP in plasma and amniotic fluid. AFP was purified from human amniotic fluid and used to immunize mice. Spleens were taken from the mice and the cells were fused with mouse myeloma cells (Sp2/0-Ag-14) for the production of monoclonal antibodies by employing the hybridoma technology. As a result, a hybridoma cell line producing anti-AFP monoclonal antibody was cloned out and designated as MabF22. From isotyping analysis, it was found that monoclonal antibody MabF22 was IgG type with IgG1 heavy chain and k light chain. The binding specificity of MabF22 was analyzed by immunoblotting as well as by ELISA. MabF22 was highly specific, reacting with only AFP-containing samples. The binding affinity was determined by ELISA (free-capture mode) and Scatchard analysis. As a result, the value of Kd was 0.8$\times$10$^{-10}$M. The validity of the MabF22 for AFP assay was examined by two kinds of ELISAs, i.e., non-competitive and competitive ELISA. Both assays revealed that MabF22 reacted well with AFP in sample in a concentration-dependent manner. Standard curve and antibody titration curve were obtained by using purified AFP and MabF22. These results indicate that the monoclonal antibody produced in this study would be useful not only for research purposes but also for further development of immune-diagnostic kit for the measurement of AEP concentration.

• The Journal of the Acoustical Society of Korea
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• v.32 no.5
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• pp.385-392
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• 2013

The sound generated from the formula 1 (F1) machine is characteristic in that the frequency felt by the listener changes drastically by the Doppler effect as the machine bypasses him. In textbooks, longitudinal Doppler effect is usually described. In this paper, we consider a more general case where the listener is away from the rectilinear path of the machine's motion. As the machine bypasses the listener, in this case, the frequency drops not abruptly but gradually, the temporal width for the frequency drop depending on the machine's speed. The frequency shift felt by the listener is analyzed as functions of time and/or machine location in our study. The machine's speed is estimated from the frequency analysis of an actual F1 sound.

• Korean Journal of Health Education and Promotion
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• v.14 no.1
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• pp.47-62
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• 1997

본 연구는 한국 보건전문가들의 보건행동을 조사하고, 보건행동간의 상호 관련 요인과 보건행동에 영향을 미치는 인구학적 요인을 분석하는데 그 목적이 있다. 본 연구 대상으로는 한국보건협회 산하의 8개의 보건 관련 학회 중에서 보건교육과 가장 관련이 있는 한국보건교육학회(212명)와 한국보건 간호학회 (124명) 회원 336명이 선정되었다. 본 연구의 도구는 미국에서 이미 실시된 여러 보건행동 연구를 기초로 하여 focus group discussion, back-translation, 전문가들의 panel discussion, 그리고 pilot test(사전조사)를 통하여 한국인의 보건행동 연구를 위해 타당하게 개발되었다. 본 연구를 위하여 1995년 약 두달동안(11월, 12월), 3차에 걸친 우편설문조사를 실시하여 64.3%의 응답회수율을 보였고, 응답자들의 보건행동을 분석하기 위해서 factor analysis(요인분석)와 ANOVA (변량분석) 방법을 사용하였다. 본 연구의 결과는 다음과 같다. 1. 조사응답자의 분포는 남자가 33.8%, 여자가 66.2%였고, 응답자의 80.3%가 석사 이상의 학위를 소유하고 있었다. 응답자들의 전공분야는 다양하였고, 그들 중에서 36.3%가 간호학, 24.4%가 공중보건학을 전공하였다. 응답자 중 과반수 이상이 학교에 근무하였고, 서울에 거주하였으며, 응답자의 평균 직장 근무연수는 14년 이였다. 2. 응답자들의 보건행동에 대한 요인분석 적용의 적합성을 사전검증하기 위하여 Bartlett’s Test of Sphericity (630.37, p〈.00)를 실시하였다. 응답자들의 보건행동을 요인분석한 결과, 17개의 보건행동으로 구성된 네가지 보건행동요인들이 추출되었다. 응답자들의 네가지 보건행동요인들은 다음과 같다: (1) 규칙적인 식사 및 과일 섭취 (2) 음주 및 흡연 (3) 외식,간식 및 카페인 음료 섭취 (4) 운동 및 휴식 3. 응답자들의 인구학적 요인과 네가지 보건행동요인들과의 관계를 분석한 결과, 성별(F=69.59, df=1,203, p〈.05), 교육정도(F=3.48, df=3,199, p〈.05) 그리고 직장(F=4.04, df=3,201, p〈.05)에 따라 음주 및 흡연 행동에 커다란 차이를 보였다. 또한 응답자의 직장 근무연수(F=2.39, df=5,185, p〈.05)에 따라 운동 및 휴식 행동에 커다란 차이를 보였다.

• Analytical Science and Technology
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• v.12 no.1
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• pp.28-33
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• 1999

Glutathione(GSH) in biological samples was determined by high performance liquid chromatographic(HPLC) method with fluorescence detector(FLD) after monobromobimane(MBB) or 4-fluoro-7-sulfobenzofurazan(SBD-F) derivatization. The detection limit of $0.03{\mu}g/mL$ was obtained after MBB derivatization, derivative of MBB was about 200 times more sensitive than that of SBD-F. N-acetylcysteine was used as internal standard and tetrabutylammonium ion as counter ion for better separation. The determination by ion-pairing chromatography after MBB derivatization was characterized by linearity in the range between $0.08{\sim}8.33{\mu}g/mL$ with a good correlation coefficient of 0.998. By precision test appeared relative standard deviation at less than 5% at three different concentrations. This method can be used for the analysis of GSH in plasma and tissue.

• Horticultural Science & Technology
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• v.32 no.3
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• pp.318-329
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• 2014

In order to gain insight into the physiological responses of plants to high temperature stress, the effects of temperature on Chinese cabbage (Brassica campestris subsp. napus var. pekinensis cv. Detong) were investigated through analyses of photosynthesis and chlorophyll fluorescence under 3 different temperatures in the temperature gradient tunnel. Growth (leaf length and number of leaves) during the rosette stage was greater at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures than at ambient temperature. Photosynthetic $CO_2$ fixation rates of Chinese cabbage grown under the different temperatures did not differ significantly. However, dark respiration rate was significantly higher in the cabbage that developed under ambient temperature relative to elevated temperature. Furthermore, elevated growth temperature increased transpiration rate and stomatal conductance resulting in an overall decrease of water use efficiency. The chlorophyll a fluorescence transient was also considerably affected by high temperature stress; the fluorescence yield $F_J$, $F_I$, and $F_P$ decreased considerably at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures, with induction of $F_K$ and decrease of $F_V/F_O$. The values of RC/CS, ABS/CS, TRo/CS, and ETo/CS decreased considerably, while DIo/CS increased with increased growth temperature. The symptoms of soft-rot disease were observed in the inner part of the cabbage heads after 7, 9, and/or 10 weeks of cultivation at ambient $+4^{\circ}C$ and ambient $+7^{\circ}C$ temperatures, but not in the cabbage heads growing at ambient temperature. These results show that Chinese cabbage could be negatively affected by high temperature under a future climate change scenario. Therefore, to maintain the high productivity and quality of Chinese cabbage, it may be necessary to develop new high temperature tolerant cultivars or to markedly improve cropping systems. In addition, it would be possible to use the non-invasive fluorescence parameters $F_O$, $F_V/F_M$, and $F_V/F_O$, as well as $F_K$, $M_O$, $S_M$, RC/CS, ETo/CS, $PI_{abs}$, and $SFI_{abs}$ (which were selected in this study), to quantitatively determine the physiological status of plants in response to high temperature stresses.

• Science of Emotion and Sensibility
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• v.10 no.1
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• pp.69-77
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• 2007

This study surveys wet and dry thermal shrinkages of PET POY manufactured by domestic seven companies and foreign companies in Japan and Taiwan. These thermal shrinkages were measured by hank method (KSK 0215) and foray FTA-500 apparatus, and these measured data were analysed and discussed with measuring methods. The specimens prepared were PET POY 85d/72f and 120d/36f, furthermore, 250d/48f and 155d/50f PET POY were also prepared for comparison of wet and dry thermal shrinkages between Japan and domestic PET POY. And the wet and dry thermal shrinkages of each specimens were measured according to the each layer divided by 50,000m of the cake, and between and within thermal shrinkages were analysed and discussed with the domestic and foreign PET POY and measuring methods such as hank ant Toray methods.

• Science of Emotion and Sensibility
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• v.8 no.4
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• pp.415-422
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• 2005

The purpose of the present study was to investigate the differences of nonlinear characteristics of electroencephalogram (EEG) depending on different sensitivities of behavioral activation system (BAS) and behavioral inhibition system (BIS) of young and elderly groups. The EEGs from Fpl and Fp2 electrodes were recorded during resting condition. The young and elderly groups consisted of 19 and 31 healthy right-handed volunteers, respectively. We estimated 1/f scaling exponent which reflects the nonlinear dynamical complexity of EEG. As results, we found the differences of 1/f scaling exponent between young ant elderly BAS sensitive groups. The 1/f scaling exponent of young BAS sensitive group showed significantly higher values than those of elderly BAS sensitive group at the left prefrontal area (Fpl). The young BAS sensitive group had also a tendency to higher 1/f scaling exponent at the right prefrontal area (Fp2). Decrease of the 1/f scaling exponent indicates the increase of complexity and the decrease of the amount of information related to the statistical distribution. Therefore, the elderly BAS sensitive group has higher complexity than young BAS sensitive group, though they were all classified as BAS sensitive group by BAS/BIS scale. Our results suggest the possibility of correlation between BAS sensitivity an4 age.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.293-296
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• 2005

본 논문은 MMoF 시스템의 광학채널을 비선형 채널로 가정하고, 단일 반송파 전송 기법을 사용한 경우와 다중 반송파 전송 기법을 사용한 경우의 성능을 모의실험을 통하여 비교하였다. 이때 다중 반송파를 사용하는 MMoF-OFDM 시스템의 성능이 단일반송파를 이용하는 MMoF 시스템에 비해 우수함을 확인할 수 있었다. 또한, 다중 반송파를 사용하는 경우 PAPR을 개선하기 위하여 PTS 기법을 사용하면 PAPR을 낮출 수는 있었지만 시스템의 성능엔 큰 차이가 없었다.