• 대한두개안면성형외과학회지
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• 제21권2호
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• pp.123-126
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• 2020

Skin cancer, which often occurs as a result of skin exposure to ultraviolet light radiation, usually presents with characteristic abnormal features, such as ulcerative lesions, irregular morphology, bleeding, and excessive growth. Therefore, skin cancer rarely resembles a benign tumor on visual inspection. Nonetheless, squamous cell carcinoma and basal cell carcinoma with nodular or polypoid features can have a similar appearance to that of benign tumors, meaning that they are sometimes misdiagnosed as benign. As benign and malignant tumors have some overlapping features, clinicians sometimes use additional imaging techniques such as ultrasonography to improve the accuracy of the diagnosis because even a malignant tumor that externally resembles a benign tumor generally has internal morphological features characteristic of malignancy, such as invasion and irregular borders. However, these imaging tools also have limitations, and punch or excisional biopsy can be needed if malignancy cannot be completely ruled out. Herein, we report a case of skin malignancy initially misdiagnosed as a benign epidermal cyst based on external visual inspection and ultrasonography.

• Journal of Trauma and Injury
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• 제19권2호
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• pp.143-149
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• 2006

Purpose: This study was done to evaluate the incidence, type of injury, medical consequences, mortality, and prognostic factors associated with stab wounds in patients who visited Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea. Methods: A retrospective analysis of the clinical data of 40 patients with abdominal stab wounds who visited Kangnam Sacred Heart Hospital, Hallym University, Seoul, Korea from January 1, 2000 to December 31, 2004. Results: 1) The most prevalent age group was patients in their the twenties to fourties (77.5% of all patients), and average age of the patients was 39.3 years. The male-to-female ratio was 2.07:1. 2) The external site of stab wounds was most commonly the periumbilcal area of the abdomen (14 cases, 33.3%). 3) The most commonly injured organs were the liver and the stomach (10 cases each, 16.9%). 4) Operations were performed on all 40 patients, with 9 (22.5%) negative operation findings. 5) Death occurred in 5 cases (12.5%). 6) The trauma indices of the death group were TRISS 51.9%, RTS 3.6 points, and APACHE II 23.0 points. 7) The average transfusion amount of the death group was 13.8 pints Conclusion: These data suggest that the transfusion amount and the trauma index of abdominal stab injuries may be statistically significant factors for predicting mortality.

• Bulletin of the Korean Chemical Society
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• 제19권2호
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• pp.160-164
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• 1998

The NADH-cytochrome b5 reductase (NCBR), a mitochondrial external electron carrier, was purified from bovine heart and turnip and their properties were examined. The mitochondrial outer membranes separated were subjected to NCBR isolation through DEAE-Cellulose ion exchange, DEAE-Sephadex gel chromatography, and hydroxyapatite adsorption chromatography. These processes yielded the purification folds of 88 and 42 and the recovery percentages of 0.2%, 5.67% for turnip and bovine heart, respectively. The molecular weight of the NCBR from the two sources was estimated to be 35,000 using SDS polyacrylamide gel electrophoresis. The Michaelis constant Km and maximum velocity Vmax were determined by measuring the NADH-ferricyanide redox system as well as the NADPH-ferricyanide redox system. The kinetics showed that both NCBRs had higher affinities for NADH than artificial electron-acceptor substrate ferricyanide. Although NADPH had a lower affinity for the enzymes than NADH, this study showed the 2'-phosphate dinucleotide could be used as a substrate.

• 대한두경부종양학회지
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• 제38권1호
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• pp.69-74
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• 2022

Endochondral pseudocyst of the ear is a rare, benign, non-inflammatory cystic disease. It is known that there are a variety of treatment methods for pseudocyst, which is mainly common in the scaphoid or triangular fossa of the ear. Pseudocyst formation is prevalent in the residual cavity of the ear. So, to prevent a recurrence, a surgical approach is also required, but management through compression is necessary after surgery. Applying a cube magnet to the lesion to press provides patient convenience and facilitates continuous management.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1993년도 춘계학술대회
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• pp.129-131
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• 1993

A transcutaneoos information transmission system using transmitted infrared light for an implantable total artificial heart(TAH) an developed and the performance of the system was tested. In an in vitro test, transmittance of the developed system was measured through various thicknesses of pig shins. In an in vivo test, a loopback test using a personal computer was performed to determine the error rate and an experiment using a mock system was taken. In this experiment, within acceptable lateral and vertical displacements, the error rate of at least 3.8E-6 was guaranteed. Monitoring signals from the internal controller(Intel 87C196) of the mock system were successfully transmitted to the external controller(IBM PC) and the operating commands from the external controller were successfully conducted by the mock system. Communication was done in half duplex mode according to RS-232 protocol at the speed of 4800 bps.

• Child Health Nursing Research
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• 제6권1호
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• pp.32-50
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• 2000

A descriptive exploratory design was used in this study to evaluate the effects of sponge bathing on physiological(heart rate, heart period, vagal tone, oxygen saturation, respiration) and behavioral responses in newly born 40 preterm infants from intensive care unit of S University Hospital in Seoul. Data has been collected from October, 1997 to March, 1999. The infants were between 27-33 weeks gestational age at birth, and were free of congenital defects. The subjects entered the protocol when they were medically stable (determined by initiation of feeding and discontinuation of all respiratory support) but still receiving neonatal intensive care. The infants' physiologic parameters were recorded a 10 - minute before, during, and after bathing. Continuous heart rate data were recorded on a notebook computer from the infant's EKG monitor. The data were digitized off-line on software(developed by Lee and Chang in Wavelet program) which detected the peak of the R wave for each heart beat and quantified sequential R-R intervals in msec(i.e. heart periods). Heart period data were edited to remove movement artifact. Heart period data were quantified as : 1) mean heart period; 2) vagal tone. Vagal tone was quantitfied with a noninvasive measure developed by Porges(1985) in Mxedit software. To determine behavioral status, tools were developed by Scafidi et al(1990) were used. Collected data were analyzed with the SPSS program using paried t-test, ANOVA, and Pearson correlation. The result were as follow. 1. The results of the ANOVAs indicated that vagal tone were signifcantly lower during bathing than baseline and post-bathing. There were significant differences in heart period and heart rate levels across the bathing. But the mean oxygen saturations and respirations were no differences. Also, there were no significant differences on behavioral sign, motor activity, behavioral distress, weight changes, morbidity, and hospitalization period. 2. To evaluate the relation between vagal tone and subsequent parameters, the two groups (the high group had 19 subjects and low group had 21subjects) were divided by the mean baseline vagal tone. Vagal tone measured prior to bathing were significantly associated with respiration before bathing, vagal tone during bathing, and the magnitude of change in both vagal tone. But, other subsequent reactivities were no differences in two groups. 3. Correlations were also calculated between vagal tone and the subsequent physiological reactivities from baseline through after- bathing. Correlations were significant between baseline vagal tone and baseline heart rate, between baseline vagal tone and baseline heart period, between baseline vagal tone and oxygen saturation after bathing. In summary, the bathing in this study showed a stressful stimulus on premature infants through there was significance in the physiological parameters. In addition, our study represents the documentation that vagal tone reactivity in response to clearly defined external stimulation provides an index of infant's status.

• 한방재활의학과학회지
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• 제31권2호
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• pp.81-97
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• 2021

Objectives This study was designed to identify the changes of autonomic nervous system (ANS) which was induced by acupuncture at the field of the auricular branch of the vagus nerve. Methods 30 healthy adults were selected and classified into two groups; experimental group, control group. After providing mental stress, acupuncture was applied at external ear in experimental group and no treatment executed in control group. The evaluation of ANS function was measured by heart rate variability (HRV). We statically analyzed the difference of HRV parameters which include mean heart rate (MHRT), standard deviation of all N-N intervals (SDNN), square root of the mean of the sum of the squares of differences between adjacent N-N intervals (RMSSD), total power (TP), low frequency power (LF), high frequency power (HF), LF/HF ratio. Results All subjects showed significant increase in SDNN, LF after stress stimulation (p<0.05). Immediately after intervention, MHRT was significantly decreased (p<0.001) and RMSSD, HF were significantly increased in experimental group (p<0.05). After the end of intervention, SDNN, HF, RMSSD, TP, LF were significantly increased in experimental group (p<0.01, p<0.05). And when comparing baseline HRV, SDNN, LF were significantly increased in control group (p<0.01) and SDNN, RMSSD, TP, LF were significantly increased in experimental group (p<0.05). In the subgroup analysis, normal balance of ANS group showed significant increase in TP, LF, SDNN, HF (p<0.01, p<0.05). Conclusions We suggested that acupuncture at external ear, region of the vagus nerve distribution could increase parasympathetic activity and cause changes and reregulation of the ANS.

• Korean Journal of Acupuncture
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• 제21권3호
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• pp.147-158
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• 2004

Objectives : This study was aimed to investigate the methods for acupuncture and moxibustional treatment to insomnia Methods : The insomnia is classified by seven cause at main subject. According to this, arrange the acupuncture and moxibustional treatment for classical books, and explain eight meridian related to insomnia. Results : 1. Insomnia means deficiency of sleeping and it is the word generally used when a short period of sleeping, difficulty for deep sleeping and difficulty for recovery of original vital energy comes out. In oriental medicine, they understand that uneasiness condition occurred by abnormal operation of the internal organs as heart, liver, gallbladder, spleen, stomach, kidney, etc. caused by external affection or internal injury becomes Insomnia. 2. Cause of insomnia can be classified majorly as fire-transformation of liver and gallbladder , inner shaking of phlegm-heat , insufficiency of both the heart and the spleen, disharmony between heat and kidney, the dysfunction of the stomach, timidity of heart and gallbladder, the deficiency of Qi of the lung. They make insomnia with bad influence upon body and spirit. 3. The meridian system such as Heart Meridian of Hand Soeum, Pericardium Meridian of Hand Gworeum, Stomach Meridian of Foot Yangmyeong, Spleen Meridian of Foot Taeeum, Bladder Meridian of Foot Taeyang, Kidney Meridian of Foot Soeum, Gallbladder Meridian of Foot Soyang, Liver Meridian of Foot Gworeum and Lung Meridian of Hand Taeeum are used to treat insomnia. Sinmun acupoint and Naegwan acupoint are often used in particular because the they are good for calmming the spirit, the heart and purging the heart of (pathogenic) fire. 4. Especialy, Back-Su points of Bladder Meridian of Foot Taeyang was used by each causes. The Back-su Points was mainly used for heal the insomnia because the Back-Su points has good competent to control the ability of internal organs by direct effect to it. It is because the vitality flows through around back-Su. Conclusions : It comes to a conclusion as follows with research for relevancy of the main cause of insomnia and meridian system includes meridian point.

• 대한기계학회논문집B
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• 제35권11호
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• pp.1213-1217
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• 2011

의료용 자극기는 병원과 가정에서 환자의 통증 경감 및 재활 치료를 위해 사용되는 의료기기이다. 전기자극기의 자극 펄스가 심장에 유입되면 부정맥 및 심실세동 등의 심각한 부작용을 초래할 수 있다. 의료용 자극기에서 공급하는 자극 펄스의 전달 거리를 측정하고 심장이 전기 자극의 위험 범위 밖에 위치하도록 자극의 크기 및 자극 부위를 제한할 필요가 있다. 전기 자극기는 초당 60 회의 빈도로 0.001Joule 전기 펄스를 가하도록 설계되었다. 전기 자극기의 성능 및 인체에 미치는 영향을 측정하기 위해 생리 식염수를 이용한 생체 조직의 모델을 제작하였고, 이를 이용하여 거리에 따른 전기장의 감쇄 정도를 측정하였다. 본 연구에서 개발한 전기 자극기를 동물실험에 적용한 후 심장 주변에 전기자극을 가했을 때 심장에서 나타나는 위험요인을 관찰하고 직류전류가 흘렀을 때 심장에서 나타나는 현상과 비교하였다.

• 대한기계학회논문집
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• 제16권11호
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• pp.2090-2097
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• 1992

본 연구에서는 밸브판의 거동을 2차의 회전계로 간주하고, 양력 및 항력(drag force)을 구하는데 있어 Reif등이 구한것과 동일한 방법을 이용하되 정지핀에 의해 그 최대 열림각이 제한을 받는 물리적 사실을 고려하고, 밸브를 통과하는 유량도 단위 입 력이 아닌 정현파(sine wave)로 간주하여 밸브판의 동적거동을 해석하였다. 해석대 상의 밸브 모델로는 Bjork-Shiley 27mm 1엽 밸브를 선정하였다.