• Communications for Statistical Applications and Methods
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• v.3 no.3
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• pp.125-133
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• 1996

In this paper, we present a algebraic technique for computing system reliability for complex system. The method was originally developed as an aid to fault tree analysis but it applies to general problems of reliability assessment. A success expression which directly gives the reliability expression is formed and simplified by the procedure. Several algorithms and examples are illustrated.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2001.08a
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• pp.103-127
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• 2001

Gene expression studies require statistical experimental designs and validation before laboratory confirmation. Various clustering approaches, such as hierarchical, Kmeans, SOM are commonly used for unsupervised learning in gene expression data. Several classification methods, such as gene voting, SVM, or discriminant analysis are used for supervised lerning, where well-defined response classification is possible. Estimating gene-condition interaction effects require advanced, computationally-intensive statistical approaches.

• Journal of the Ergonomics Society of Korea
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• v.30 no.1
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• pp.195-202
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• 2011

Objective: The aim of this study is to investigate and review the previous researches about objective measuring fatigue caused by visual stimuli. Also, we analyze possibility of alternative visual fatigue measurement methods using facial expression recognition and gesture recognition. Background: In most previous researches, visual fatigue is commonly measured by survey or interview based subjective method. However, the subjective evaluation methods can be affected by individual feeling's variation or other kinds of stimuli. To solve these problems, signal and image processing based visual fatigue measurement methods have been widely researched. Method: To analyze the signal and image processing based methods, we categorized previous works into three groups such as bio-signal, brainwave, and eye image based methods. Also, the possibility of adopting facial expression or gesture recognition to measure visual fatigue is analyzed. Results: Bio-signal and brainwave based methods have problems because they can be degraded by not only visual stimuli but also the other kinds of external stimuli caused by other sense organs. In eye image based methods, using only single feature such as blink frequency or pupil size also has problem because the single feature can be easily degraded by other kinds of emotions. Conclusion: Multi-modal measurement method is required by fusing several features which are extracted from the bio-signal and image. Also, alternative method using facial expression or gesture recognition can be considered. Application: The objective visual fatigue measurement method can be applied into the fields of quantitative and comparative measurement of visual fatigue of next generation display devices in terms of human factor.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1998.06b
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• pp.16.1-164
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• 1998

This paper describes Facial Expression Explorer to search for the components of a facial expression and to map the expression to other expressionless figures like a robot, frog, teapot, rabbit and others. In general, it is a time-consuming and laborious job to create a facial expression manually, especially when the facial expression must personify a well-known public figure or an actor. In order to extract a blending ratio from facial images automatically, the Facial Expression Explorer uses Networked Genetic Algorithm(NGA) which is a fast method for the convergence by GA. The blending ratio is often used to create facial expressions through shape blending methods by animators. With the Facial Expression Explorer a realistic facial expression can be modeled more efficiently.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5535-5538
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• 2014

Background: To determine the amount of co-expression of IDO and EGFR in breast cancer patients. Materials and Methods:In order to obtain the distribution of co-expression of IDO and EGFR in breast cancer, we tested 110 breast cancer paraffin tissue blocks with immunohistochemical methods. Then we investigated the relationship between the diagnostic and pathologic characteristics (tumor size, lymph node status, histologic grade, the gene expression of ER, PR, HER2, p53, Ki67 and PCNA) with the situation of co-expression of IDO and EGFR by reviewing the medical records of 32 breast cancer patients. Results: Among 110 breast cancers, 32 cases demonstrated IDO and EGFR co-expression (29.1%), IDO and EGFR synchronous co-expression being found in 19.1% and asynchronous in 10.0%. Conclusions: IDO and EGFR were co-expressed in breast cancer, including synchronous and asynchronous co-expression. The results suggest that considering IDO and EGFR as two indicators for breast cancer treatment or prognosis analysis provides a potential option of individual treatment for the portion of breast cancer patients with co-expression of IDO and EGFR.

• Journal of Korea Society of Digital Industry and Information Management
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• v.9 no.4
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• pp.201-212
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• 2013

The purpose of this study are to show a new possibility of identity design to be used as tools of users identity expression, designing digital contents by studying on the methods to express users identities successfully in the digital contents design, and to present the possibility to expand the area of identity design. Digital contents are a communication media in it self, but this study tried to consider the digital contents as a tool of users communication or expression. The identity expression, which are not only makes communications efficient but also lets products and companies acknowledged by users, is one of the most indispensable factors in products competitive power in both the present and the future. However, no define methods of identity expression are settled as well as recognized by users properly and accurately yet, so that this study focuses on that point. Therefore, This study is advanced in the direction of establishing the concept of digital identity for an expansion of the media toward the identity expression in design as well as making researchers in successful identity expression ways by means of actual design, more than a graphic image making that simply decorates a digital contents. The point of this study is to show a new concept of identity design that expresses users identities so as to suggest another possibility of identity design.

• The Korean Journal of Nuclear Medicine
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• v.38 no.6
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• pp.511-515
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• 2004

Purpose: The sodium-iodide symporter (NIS) expression is an important factor in determining the sensitivity of radioiodine therapy in well-differentiated thyroid cancers. Several previous studies for the expression of NIS in thyroid tissues show diverse results. To investigate whether there is difference between methods in determining the expression of NIS in thyroid tissues of patients with thyroid nodules, we measured the expression ot NIS using two different methods (RT-PCR and immunoshistochemical staining) and compared the results. Materials & Methods: We measured the expression of NIS by reverse transcriptase-polymerase chain reaction (RT-PCR) and also by immunohistochemical staining using anti-NIS antibody in thyroid cancers and other benign thyroid diseases. We compared the results of each method. We included 19 papillary carcinomas, 1 follicular carcinoma, 7 medullary carcinoma, 4 adenomas and 7 nodular hyperplasias. Results: By RT-PCR analysis, 10 of 19 papillary carcinomas expressed NIS, but 1 follicular cancer didn't express NIS. By immunohistochemical staining, 15 of 19 papaillary carcinomas express NIS, but 1 follicular lancer didn't express NIS. There was a significant correlation between the semiquautitative results of RT-PCR and immunohistochemical staining of NIS expression. (p<0.01) Conclusion: Our data demonstrated that the expression of NIS in thyroid cancers and other benign diseases investigated by RT-PCR and immunohistochemical staining correlated well each other. However, by immunohistochemical staining, more NIS expression was found.

• International journal of thyroidology
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• v.11 no.2
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• pp.143-151
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• 2018

Background and Objectives: Sirtuins (SIRTs) play important roles in cellular and organismal homeostasis. They have distinct gene expression patterns in various cancers; however, the relationship between SIRT expression and the progression of thyroid cancer is unclear. We investigated the expression of SIRTs in patients with papillary thyroid carcinoma (PTC) and their role as biomarkers for predicting the aggressiveness of this disease. Materials and Methods: We used immunohistochemical staining to evaluate the expression of SIRT1 and SIRT3 in tumor specimens from 270 patients with PTC. We also evaluated the potential association between SIRT expression and diverse clinicopathological features. Results: High SIRT1 expression was negatively correlated with lymphovascular invasion, central lymph node metastasis, and lateral lymph node metastasis. Multivariate analyses revealed that high SIRT1 expression was a negative independent risk factor for lateral lymph node metastasis. By contrast, high SIRT3 expression was positively correlated with locoregional recurrence. Interestingly, when patients were grouped by tumor SIRT expression patterns, the group with low SIRT1 expression and high SIRT3 expression was correlated with more aggressive cancer phenotypes including central lymph node metastasis and lateral lymph node metastasis. Conclusion: Our results suggest that SIRTs play dual roles in tumor progression, and the combination of decreased SIRT1 expression and increased SIRT3 expression is significantly associated with a poor prognosis in patients with PTC.

• The Research Journal of the Costume Culture
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• v.12 no.5
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• pp.721-736
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• 2004

The aim of this study is to clarify aesthetic values and sociocultural meanings that reappears in contemporary fashion. In order to analyze aesthetic values and symbolic meanings of body decoration, I examined the concepts and expression methods of the body decoration. Also, analyzed external characteristics of expression and its internal meanings that applied in modern fashion. The expressions of body decoration represented in contemporary fashion are classified into direct and indirect methods. The direct method is expressed by tattoos, piercing, henna, make-up and body painting. And, indirect method is expressed by see-through look, body-conscious look and accessories that were utilized its patterns and the material adaptation methods. Such expression of body decoration in the modern fashion was represented into grotesque images and erotic images. The characteristics of grotesque images are abnormal state, hateful animal image and distorted or transformed body and the internal meanings are the pursuit of primitive, exoticism, the pursuit of playfulness, and resistance. The characteristics of erotic images are an exposure of body, see through, body-conscious and androgynous look and the internal meanings are the self-intoxication, naturalism and sexual pleasure.

• International Journal of Computer Science & Network Security
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• v.23 no.1
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• pp.125-139
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• 2023

Facial expression recognition, a topical problem in the field of computer vision and pattern recognition, is a direct means of recognizing human emotions and behaviors. This paper first summarizes the datasets commonly used for expression recognition and their associated characteristics and presents traditional machine learning algorithms and their benefits and drawbacks from three key techniques of face expression; image pre-processing, feature extraction, and expression classification. Deep learning-oriented expression recognition methods and various algorithmic framework performances are also analyzed and compared. Finally, the current barriers to facial expression recognition and potential developments are highlighted.