• Title/Summary/Keyword: exposure correction

검색결과 115건 처리시간 0.022초

환경유래 식품오염물질의 우선순위 선정 기법 (Food-CRS-Korea)의 개발과 적용 (Development of Korean Food-Chemical Ranking and Scoring System (Food-CRS-Korea) and Its Application to Prioritizing Food Toxic Chemicals Associated with Environmental Pollutants)

  • 양지연;장지영;김수환;김윤관;이효민;신동천;임영욱
    • Environmental Analysis Health and Toxicology
    • /
    • 제25권1호
    • /
    • pp.41-55
    • /
    • 2010
  • The aims of this study were to develop the suitable "system software" in chemical ranking and scoring (CRS) for the food hazardous chemicals associated with environmental emission and to suggest the priority lists of food contamination by environmental-origined pollutants. Study materials were selected with reference to the priority pollutants list for environment and food management from domestic and foreign research and the number of study materials is 103 pollutants (18 heavy metals, 10 PBTs, 10 EDs, and 65 organic compounds). The Food-CRS-Korea system consisted of the environmental fate model via multimedia, transfer environment to food model, and health risk assessment by contaminated food intake. We have established that health risks of excess cancer risks, hazard quotients (HQs) by chronic toxicity and HQs by reproductive toxicity convert to score, respectively. The creditable scoring system was designed to consider uncertainty of quantitative risk assessment based on VOI (Value-Of-Information). The predictability of the Food-CRS-Korea model was evaluated by comparing the presumable values and the measured ones of the environmental media and foodstuffs. The priority lists based on emissions with background-level-correction are 15 pollutants such as arsenic, cadmium, and etc. The priority lists based on environmental monitoring date are 17 pollutants including DEHP, TCDD, and so on. Consequently, we suggested the priority lists of 13 pollutants by considering the several emission and exposure scenarios. According to the Food-CRS-Korea system, arsenics, cadmium, chromes, DEHP, leads, and nickels have high health risk rates and reliable grades.

관상동맥질환을 동반한 대동맥류 수술치험 1례 (Surgical Correction of Thoracic Aortic Aneurysm Associated with Coronary Artery Disease A Case Report -A Case Report-)

  • 우종수;서정욱
    • Journal of Chest Surgery
    • /
    • 제30권7호
    • /
    • pp.724-728
    • /
    • 1997
  • 68세된 남자로 좌측과 후측 흉부에 통증을 주소로 내원하였다. 술전 시행한 흉복부 W scan에서 대동맥류는 좌측 쇄골하동맥에서 횡격막까지 연결되었고 긴박성 파열의 소견도 보였다. 또한 술전 관동맥조영술에서는 좌회선동맥에 95%, 좌전하행지에 50%의 협착소견을 보였다. 수술은 고동맥-고정맥 우회술을 하면서 좌측 제 4늑간을 통하여 측후방 개흉절개를 하여 수술시야를 확보하였고 대동맥을 차단한뒤 대동맥류를 절개하고 인조혈관으로 대치하였다. 그리고 심박동하에서 대복제정 맥을 이용하여 좌회선동맥의 두번째 둔각변연동맥과 좌측 쇄골하동맥 기시부에 관상동맥 우회술을 하였다. 술후 환자는 술중 저혈압성 쇼크와 저산소증으로 다발성 뇌경색의 합병증을 보였다.

  • PDF

투과선량의 수치해석에 의한 전산화단층영상장치 X선의 에너지 분포결정 (Empirical Determination of a CT X-ray Spectra by Numerical Analysis using Transmission Data)

  • 최태진;김옥배;서수지
    • 한국의학물리학회지:의학물리
    • /
    • 제8권2호
    • /
    • pp.35-43
    • /
    • 1997
  • 광자선의 흡수계수교정과 차등 투과력이 관련된 연구에서 X선의 스펙트럼은 중요한 관심사이다. 본 연구에서는 전산화단층영상장치의 80, 120 kVp X선의 실험적 투과선량으로부터 수치해석을 통해 에너지스펙트럼을 구하였다. 투과선량은 직경 30cm, 두께 5mm 내지 92.3 mm의 알루미늄 파이프필터의 중앙에 반도체검출기를 설치하고 10mm 슬릿빔의 투과선량을 측정하였다. 스펙트럼재구성은 텅스텐타켓의 특성 X선을 포함한 반복적 수치 해석을 통해 에너지 구간별 스펙트럼을 구하였으며 에너지구간은 2keV로 하였다. 재구성한 에너지분포를 이용하여 계산된 투과선량과 측정투과선량의 비교는 두 광자에너지에서 모두 좋은 일치를 보였다. 에너지구간별 분할조사선량의 반복적 계산에 근거를 둔 수치해석은 흡수체의 감쇄된 선속으로부터 X선의 에너지스펙트럼을 매우 유용하게 결정할 수 있음을 보여주었다.

  • PDF

Gene Expression Analysis of So Called Asian Dust Extracts in Human Acute Myeloid Leukemia Cells

  • Choi, You-Jin;Yin, Hu-Quan;Park, Eun-Jung;Park, Kwang-Sik;Kim, Dae-Seon;Lee, Byung-Hoon
    • Toxicological Research
    • /
    • 제26권1호
    • /
    • pp.21-28
    • /
    • 2010
  • As the frequency and the intensity of so called Asian dust (AD) events have increased, public concerns about the adverse health effects has spiked sharply over the last two decades. Despite the recent reports on the correlation between AD events and the risk for cardiovascular and respiratory disease, the nature of the toxicity and the degree of the risk are yet largely unknown. In the present study, we investigated the effects of the dichloromethane extract of AD (AD-X) and that of urban dust (NAD-X) collected during a non-AD period on gene expression in HL-60 cells using Illumina Sentrix HumanRef-8 Expression BeadChips. Global changes in gene expression were analyzed after 24 h of incubation with 50 or 100 ${\mu}g$/ml AD-X and NAD-X. By one-way analysis of variance (p < 0.05) and Benjamini-Hochberg multiple testing correction for false discovery rate of the results, 573 and 297 genes were identified as AD-X- and NAD-X-responsive, respectively. The genes were classified into three groups by Venn diagram analysis of their expression profile, i.e., 290 AD-X-specific, 14 NAD-X-specific, and 283 overlapping genes. Quantitative realtime PCR confirmed the changes in the expression levels of the selected genes. The expression patterns of five genes, namely SORL1, RABEPK, DDIT4, AZU1, and NUDT1 differed significantly between the two groups. Following rigorous validation process, these genes may provide information in developing biomarker for AD exposure.

구개 접근법에 의한 협골 축소 성형술 (REDUCTION MALARPLASTY THROUGH INTRAORAL APPROACH)

  • 우순섭;김명진;민병일
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • 제15권3호
    • /
    • pp.171-177
    • /
    • 1993
  • The prominent malar region has been recognized a sign of youth and beauty in caucasian who generally have a dolichocephalic and long face. But in the orients, especially Koreans who generally have a mesocephalic or brachycephalic face, it is considered an agressive, unesthetic facial appearance. So many patients require the shaving of prominent malar eminence and arch, and many methods of its reduction have been devised. For the exposure of malar complex, infraorbital skin incision, intraoral approach, preauricular approach, supraauricular scalp incision, and coronal approach have been used. And for the reduction of bony structure, direct shaving, contouring and repositioning of the malar complex after extirpation, and medially fracture of zygomatic arch have been used with its own merits. We performed the reduction malarplasty through intraoral approach. After two parallel oeteotomy at medial part of the zygomatic bone, the midsegment is removed. The posterior arch of zygoma was bended or green stick fractured. When more correction was required, the posterior arch was fractured medially through the step incision at skin. This method has a some advantages. Compared with the method for extirpation of malar complex, the infection rate is diminished, the resorption is small because of no free bone graft. And cheek drooping is prevented. Compared with the method of coronal approach, the surgical trauma is minimal. Now we report some cases of reduction malarplasty performed through intraoral approach and disscus the surgical technique and results.

  • PDF

보존연한 도래 및 법적기준 준수를 위한 개인정보 정책적 폐기시스템을 활용한 폐기 누적현황 데이터베이스 구축에 관한 방안 제안 (A Proposal of Methods for Building Databases about the Accumulation of Disuse Utilizing the Political System to Discard Private Information According to the Expiration of In-service Life and Observation of Legal Standards)

  • 서우석
    • 디지털산업정보학회논문지
    • /
    • 제14권3호
    • /
    • pp.45-53
    • /
    • 2018
  • The Personal Information Protection Act has been revised continuously since its establishment, and as a way to secure stability properly, the guidelines as well as enforcement ordinances and regulations have been changed, too. It seems that people's recognition and awareness of private information have already evolved to a certain level that is regarded to be fairly high. However, no one can exactly imagine how much ripple effect scrapping discarded paper regarded simply as waste material which is often and easily practiced in our everyday lives exerts and how many socially significant events it may arouse in our lives. Private information is produced, operated, preserved, utilized, distributed within the frame of law unidentified, and then discarded with a particular purpose. While going through a series of processes, each piece of that private information comes to be reproduced melting a lot of information. It is used and also changed beneficially sometimes to richen our lives or as basic material for welfare. Meanwhile, its importance is decided by its weight or mass and then often gets discarded after all. It means that the process of disuse is being done in a way to arouse the possibility of invasion of personal rights and also the second and third and also more exposure of private information. Therefore, approaching the meaning of automation politically, this study aims to suggest how to secure stability in the process of discarding private information in terms of logical automation.

전자문서의 안전한 보관 및 발급 서비스 확보를 위한 시스템 설계 (System Design for the Safe store and Issue Service Assurance of the E-Document)

  • 성경상;김정재;오해석
    • 한국컴퓨터정보학회논문지
    • /
    • 제13권6호
    • /
    • pp.173-180
    • /
    • 2008
  • 공인전자문서보관소는 전자기록의 진본성을 확인하고 보장하는 제도로서 법적인 보호 아래 보관되며, 전자기록 사항을 진정한 것으로 추정하고 전자기록의 내용이 변경되지 않았음을 입증한다. 그러나, 전자기록은 매체의존도가 높고 정보의 유실위험이 매우 높은 문제점을 가진다. 또한, 정보의 첨삭(첨부와 삭제)과 수정이 용이하기 때문에 전자기록의 진본성과 무결성에 대한 문제가 야기되고 있다. 현존하는 시스템에서는 다음과 같은 비효율성을 드러내고 있다. 원본성 보장을 위한 기존의 전자문서 암호화 방법은 하나의 대칭키로 전체 문서의 암호화 과정을 수행하며, 중간에 수정되어지는 정보가 발생시에는 해당 문서 전체 내용을 재스캔 및 재암호화 과정을 수행해야 한다. 이러한 비효율성을 극복하기 위해, 본 논문에서는 등록 요청된 전자문서에 대해 페이지의 연관성을 기반으로 하는 Link 정보를 이용하여 암호화하고 관리함으로써 해당 문서의 부분 정보 수정 요청시 발생하는 비용적 효율성을 극대화시켰으며, 키 관리의 복잡도를 증가시켜 정보 노출에 따른 문제점을 최소화함으로써 보안성을 향상시켰다.

  • PDF

Microplate Fixation without Maxillomandibular Fixation in Double Mandibular Fractures

  • Song, Seung Wook;Burm, Jin Sik;Yang, Won Yong;Kang, Sang Yoon
    • 대한두개안면성형외과학회지
    • /
    • 제15권2호
    • /
    • pp.53-58
    • /
    • 2014
  • Background: Maxillomandibular fixation (MMF) is usually used to treat double mandibular fractures. However, advancements in reduction and fixation techniques may allow recovery of the premorbid dental arch and occlusion without the use of MMF. We investigated whether anatomical reduction and microplate fixation without MMF could provide secure immobilization and correct occlusion in double mandibular fractures. Methods: Thirty-four patients with double mandibular fractures were treated with open reduction and internal fixation without MMF. Both fracture sites were surgically treated. For bony fixations, we used microplates with or without wire. After reduction, each fracture site was fixed at two or three points to maintain anatomical alignment of the mandible. Interdental wiring was used to reduce the fracture at the superior border and to enhance stability for 6 weeks. Mouth opening was permitted immediately. Results: No major complications were observed, including infection, plate exposure, non-union, or significant malocclusion. Five patients experienced minor complications, among whom the only one patient experienced a persistant but mild malocclusion with no need for additional management. Conclusion: This study showed that double mandibular fractures correction with two-or three-point fixation without MMF simplified the surgical procedure, increased patient comfort, and reduced complications, due to good stability and excellent adaptation.

Influence of modeling agents on the surface properties of an esthetic nano-hybrid composite

  • Kutuk, Zeynep Bilge;Erden, Ecem;Aksahin, Damla Lara;Durak, Zeynep Elif;Dulda, Alp Can
    • Restorative Dentistry and Endodontics
    • /
    • 제45권2호
    • /
    • pp.13.1-13.10
    • /
    • 2020
  • Objective: The aim of this study was to evaluate the influence of different modeling agents on the surface microhardness (Vickers hardness number; VHN), roughness (Ra), and color change (ΔE) of a nano-hybrid composite with or without exposure to discoloration by coffee. Materials and Methods: Sixty-four cylinder-shaped nano-hybrid composite specimens were prepared using a Teflon mold. The specimens' surfaces were prepared according to the following groups: group 1, no modeling agent; group 2, Modeling Liquid; group 3, a universal adhesive (G-Premio Bond); and group 4, the first step of a 2-step self-adhesive system (OptiBond XTR). Specimens were randomly allocated into 2 groups (n = 8) according to the storage medium (distilled water or coffee). VHN, Ra, and ΔE were measured at 24 hours, 1 week, and 6 weeks. The Kruskal-Wallis test followed by the Bonferroni correction for pairwise comparisons was used for statistical analysis (α = 0.05). Results: Storage time did not influence the VHN of the nano-hybrid composite in any group (p > 0.05). OptiBond XTR Primer application affected the VHN negatively in all investigated storage medium and time conditions (p < 0.05). Modeling Liquid application yielded improved Ra values for the specimens stored in coffee at each time point (p < 0.05). Modeling Liquid application was associated with the lowest ΔE values in all investigated storage medium and time conditions (p < 0.05). Conclusion: Different types of modeling agents could affect the surface properties and discoloration of nano-hybrid composites.

유아기의 개심술14례 보고 (Open Heart Surgery During The First 12 Months Of Life)

  • 안혁;서경필
    • Journal of Chest Surgery
    • /
    • 제14권4호
    • /
    • pp.381-387
    • /
    • 1981
  • Fourteen Infants with congenital cardiac anomalies underwent primary surgical Intervention within the first 12 months of life. There were eight patients with ventricular septal defect, two with total anomalous pulmonary venous return [TAPVR], and the remainders with tetralogy of Fallot, transposition of great arteries [d-TGA], Taussing-Bing malformation, and coronary A-V fistula. The age of the patients ranged from 5 to 12 months, with a mean age of 9.9 months. The mean weight was 6.7 Kg [3.8 to 9.5 KS]. Congestive heart failure persisting despite intensive medical treatment was present In 8 patients [56%], and was the most common indication for operation. Early operation was necessary in 5 of these patients [35%], because of failure to thrive and recurrent pulmonary infection. In one patient with TOF, frequent hypoxic spell prompted the necessity for early operation. In cases of VSD, TAP. VR, TOF, and coronary A-V fistula, Intracardiac repair was done with conventional cardiopulmonary bypass, chemical cold cardioplegia, and topical myocardial cooling. Deep hypothermic circulatory arrest with surface induced cooling, followed by core cooling and core rewarming, was employed .for better exposure in the cases of d-TGA and Taussing-Bing malformation. The results were however, not satisfactory. The overall mortality was 28 per cent. There were no deaths in the eight patients with VSD. The one with coronary A-V fistula survived. The other 5 cases all expired either on the table or immediately after operation. The non-fatal post-operative complications included low cardiac output, respiratory insufficiency, bleeding, and temporary A-V block. The causes of death were prolonged circulatory arrest time in d-TGA, complete A-V block and low cardiac output in TOF and Taussing-Bing malformation and prolonged bypass time and Inadequate correction in TAPVR.

  • PDF