• Title/Summary/Keyword: exposed specimen

Search Result 293, Processing Time 0.024 seconds

Diagnostic Value of Protein Ki67 (MIB-1) in Atypical Pap Smears of Postmenopausal Women

  • Fakhrjou, Ashraf;Dastranj-Tabrizi, Ali;Ghojazadeh, Morteza;Ghorashi, Sona;Velayati, Atefeh;Piri, Reza;Vahedi, Amir;Sayyah-Melli, Manizhe;Smaeili, Heydar-Ali;Bonakdari, Amir;Halimi, Monireh;Naghavi-Behzad, Mohammad
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.8
    • /
    • pp.4815-4818
    • /
    • 2013
  • Background: Atrophic epithelium of cervix sampled from postmenopausal women may mimic high-grade cervical intraepithelial neoplasia in Papanicolaou-stained (Pap) smears. Ki-67 (MIB-1) protein presents on proliferating cells, and percentage of cells with positive nuclei provides a reliable tool for rapid evaluation of the growth fraction. The aim of this study was to determine the diagnostic value of protein Ki67 staining in atypical pap smears of postmenopausal women. Methods: In a case-control setting, pap smears of 75 women with an atypical pap smear (case group) and 75 with normal pap smears (controls) were obtained before and after estrogen treatment. Afterward, samples were exposed to the monoclonal antibody Ki-67 (MIB-1) and the immunohistochemically demonstrated Ki-67+ cells were compared. Results: Mean ages of cases and controls were $60.4{\pm}4.5$ and $59.9{\pm}4.3$ years respectively (P=0.50). There was one (2.7%) positive Ki-67 specimen in the case group, without any positive Ki-67 specimen in the control group (P=0.50). Conclusions: Measurement of proliferative activity index in Pap smears restrained with MIB1 is a simple, reliable, and cost-effective method for excluding negatives. This would imply that it might allow a substantial reduction of diagnostic estrogen courses and subsequent Pap smears in postmenopausal women with atypical findings.

A Study on the 43$0^{\circ}C$ Degradation Behavior of Cast Stainless Steel(CF8M)(II)-Evaluation of Low Cycle Fatigue Characteristics- (주조 스테인리스강 CF8M의 43$0^{\circ}C$ 열화거동에 관한 연구 (II) -저사이클 피로특성 평가-)

  • Gwon, Jae-Do;U, Seung-Wan;Park, Jung-Cheol;Lee, Yong-Seon;Park, Yun-Won
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.24 no.9 s.180
    • /
    • pp.2183-2190
    • /
    • 2000
  • A thermal aging is observed in a primary reactor cooling system(RCS) made of a casting stainless steel when the RCS is exposed for long period at the reactor operating temperature, 290~3300C An investigation of effects of thermal aging on a low cycle fatigue characteristics included a stress variations caused by a reactor operation and trip, is required. The purpose of the present investigation is to find an effect of a thermal aging of the CF8M on a low cycle fatigue life. The specimen of CF8M are prepared by an artificially accelerated aging technique holding 300 and 1800hr at 4300C respectively. The low cycle fatigue tests for the virgin and two aged specimens are performed at the room temperature for various strain amplitudes($\varepsilon$ta), 0.3, 0.5, 0.8, 1.0, 1.2 and 1.5% strain. Through the experiment, it is found that the fatigue life is rapidly reduced with an creasing of the aging time. The experimental fatigue life estimation formulas between the virgin and two aged specimen are obtained and are proposed to a analysis purpose.

Influence of toothbrush abrasion and surface treatments on the color and translucency of resin infiltrated hybrid ceramics

  • Labban, Nawaf;Al Amri, Mohammad;Alhijji, Saleh;Alnafaiy, Sarah;Alfouzan, Afnan;Iskandar, Mounir;Feitosa, Sabrina
    • The Journal of Advanced Prosthodontics
    • /
    • v.13 no.1
    • /
    • pp.1-11
    • /
    • 2021
  • PURPOSE. The study compared the color change, lightness, and translucency of hybrid resin ceramics exposed to toothbrush abrasion and surface treatment. MATERIALS AND METHODS. Four hybrid ceramics [Lava Ultimate (LU), Vita Enamic (EN), Shofu HC (SH), and Crystal Ultra (CU)] were compared with a glass-ceramic (Vita Mark II) control. One hundred and twenty specimen blocks were prepared using a precision saw machine. Specimens in each material were divided into four subgroups based on the surface treatment (polishing or staining) and a storage medium (water or citric acid). Simulated tooth brushing with a mixture of 100 RDA (radioactive abrasives) with 0.3 ml distilled water was used for 3650 cycles (7300 strokes) for each specimen. Measurements for the color change, lightness, and translucency were measured after toothbrushing using a spectrophotometer. Statistical analysis compared outcomes using paired t-test, ANOVA, and Tukey post hoc test. RESULTS. The maximum color change was identified in SH (stained acid) [1.44 (0.40)], whereas the lowest was identified in EN (polished water) [0.66 (0.16)] material. The maximum and minimum loss of surface translucency was observed in SH (polished water) [12.3 (0.52)] and EN (stained acid) [6.5 (0.55)] specimens, respectively. Lastly, loss of lightness was the highest in VM (polished acid) [69 (0.95)], whereas the lowest was observed in CU (stained water) [56.7 (0.86)]. CONCLUSION. The comparison presented a significant effect of toothbrush abrasion on translucency and lightness of the hybrid resin ceramics. Color change was not significantly influenced irrespective of the storage medium employed. Surface staining demonstrated the preservation and stability of color and optical properties under the influence of toothbrush abrasion and chemical trauma.

Moisture Absorption and Strengths of Composite Skins cured on the Close Heated Mold (폐쇄형 가열 금형에서 경화된 복합재 외피의 수분흡수 및 강도특성)

  • Kyung-Su Kim;Hyeon-Seok Choe;Byeong-Su Kwak;Jin-Hwe Kweon
    • Composites Research
    • /
    • v.37 no.2
    • /
    • pp.126-131
    • /
    • 2024
  • The moisture absorption rate and structural strength changes of oven-cured composite skin based on closed molds were studied. Moisture absorption was performed on specimens with and without filler applied. The specimens were exposed to moisture for up to 231 days. Tensile and compression tests were conducted with and without filler application. As a result of the test, the moisture absorption rates of the tensile and compressive specimens without filler were 2.4 and 0.3% higher, respectively, than those with the filler applied. The tensile and compressive strengths of the specimen without filler applied were average 305 MPa and 139 MPa, respectively, and the tensile and compressive strengths of the specimen with filler applied were 313 MPa and 166 MPa, respectively, appeared high.

Axial compressive behavior of partially encased recycled aggregate concrete stub columns after exposure to high temperatures

  • Jiongfeng Liang;Wanjie Zou;Liuhaoxiang Wang;Wei Li
    • Steel and Composite Structures
    • /
    • v.52 no.2
    • /
    • pp.121-134
    • /
    • 2024
  • To investigate the compressive behavior of partially encased recycled aggregate concrete (PERAC) stub columns after exposed to elevated temperatures, 22 specimens were tested. The maximum temperature suffered, the replacement ratio of recycled coarse aggregate (RCA), the endurance time and the spacing between links were considered as the main parameters. It was found that the failure mode of post-heated PERAC columns generally matched that of traditional partially encased composite (PEC) columns, but the flange of specimens appeared premature buckling after undergoing the temperature of 400℃ and above. Additionally, the ultimate strength and ductility of the specimens deteriorated with the elevated temperatures and extended heating time. When 400℃< T ≤ 600℃, the strength reduction range is the largest, about 11% ~ 17%. The higher the replacement ratio of RCA, the lower the ultimate strength of specimens. At the temperature of 600℃, the ultimate strength of specimens with the RCA replacement ratio of 50% and 100% is 0.94 and 0.91 times than that of specimens without RCA, respectively. But the specimen with 50% replacement ratio of RCA showed the best ductility performance. And the bearing capacity and ductility of PERAC stub columns were changed for the better due to the application of links. When the RCA replacement ratio is 100%, the ultimate strength of specimens with the link spacing of 100 mm and 50 mm increased 14% and 25% than that of the specimen without links, respectively. Based on the results above, a formula for calculating the ultimate strength of PERAC stub columns after exposure to high temperatures was proposed.

The Relationship for Socioeconomic Factors and the Violence Victim (폭력 손상과 일부 사회경제적 요인의 관련성)

  • Kim, Jaeik
    • Journal of Digital Convergence
    • /
    • v.10 no.10
    • /
    • pp.415-421
    • /
    • 2012
  • The purposes of this thesis are to grasp the aspect of injuries by violence which is the recent social issue, analyze the relationship with socioeconomic factors and provide it as the basic material of policy development and prevention. With the specimen in-depth investigation materials of injured patients of emergency room which is injuries examination system based on medical institution, this thesis compared injuries by violence with aspect of other injuries and conducted logistic regression analysis after controlling gender, age, educational level and occupation mutually. Women showed more danger to be exposed to injuries by violence than men. The less the age was, the more danger by violence was. The more academic background was, the less rate to be exposed to violence was. For occupations, there were dangerous in order of service workers, shop and market sales workers, unemployed, elementary occupations. In conclusion, Some differences of socioeconomic factors made an effect on the danger of injuries by violence victim.

A Study on the Micro-fracture Behavior of the MEMS Material at Elevated Temperature (고온용 MEMS 재료의 마이크로 파괴거동에 관한 연구)

  • Woo, Byung-Hoon;Bae, Chang-Won;Moon, Kyong-Man;Bae, Sung-Yeol;Higo, Yakichi;Kim, Yun-Hae
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.31 no.5
    • /
    • pp.550-555
    • /
    • 2007
  • The effective fracture toughness testing of materials intended for application in Micro Electro Mechanical Systems (MEMS) devices is required in order to improve understanding of how micro sized material used in device may be expected to perform upon the micro scale. ${\gamma}$-TiAl based materials are being considered for application in MEMS devices at elevated temperatures. Especially, in Alloy 4, both ${\alpha}_2$ and ${\gamma}$ lamellae were altered markedly in 3,000 h, $700^{\circ}C$ exposure. Parallel decomposition of coarse ${\alpha}_2$ into bunches of very fine (${\alpha}_2+{\gamma}$) lamellae. Parallel decomposition of coarse ${\alpha}_2$ into bunches of very fine (${\alpha}_2+{\gamma}$) lamellae. The materials were examined 2 types Alloy 4 on heat exposed specimen($700^{\circ}C$, 3,000 h) and no heat exposed one. Micro sized cantilever beams were prepared mechanical polishing on both side at $25{\sim}30{\mu}m$ and electro final stage polishing to observe lamellar orientation of same colony with EBSD (Electron Backscatter Diffraction Pattern). Through lamellar orientation as inter-lamellae or trans-lamellae, Cantilever beam was fabricated with Focused Ion Beam(FIB). The directional behavior of the lamellar structure was important property in single material, because of the effects of the different processing method and variations in properties according to lamellar orientation. In MEMS application, it is first necessary to have a reliable understanding of the manufacturing methods to be used to produce micro structure.

The Effect of Thermal Exposure on the Microstructural Evolution and Tensile Properties in Cast Hastelloy X (Hastelloy X 주조재의 열간 노출에 따른 미세조직 및 인장 특성 변화)

  • Choi, Baig Gyu;Kim, In Soo;Do, Jeonghyeon;Jung, Joong Eun;Jung, In Yong;Hong, Hyun Uk;Jo, Chang Yong
    • Journal of Korea Foundry Society
    • /
    • v.37 no.5
    • /
    • pp.139-147
    • /
    • 2017
  • Microstructural evolution of cast Hastelloy X during thermal exposure has been investigated. OM, SEM, and TEM microscopy were carried out on the as-cast, the standard heat treated, and the thermally exposed conditions. Tensile tests were also conducted to understand the effect of microstructural evolution on the degradation of tensile properties. Coarse $M_6C$ and fine $M_{23}C_6$ carbides were found in as-cast Hastelloy X with fine carbides on sub-boundary. Some of $M_{23}C_6$ carbide dissolved into the matrix during solution heat treatment and dislocation network formed at the interface between the carbide and the matrix due to the misfit strain. There was no significant microstructural difference between the exposed specimens at $400^{\circ}C$ and the solution heat treated specimen. A large amount of $M_{23}C_6$ carbides precipitated along and near grain boundaries and sub-boundaries after exposure at $650^{\circ}C$. Exposure at $870^{\circ}C$ of the alloy caused precipitation of $M_6C$ and ${\mu}$. The strength increased and the elongation decreased by thermal exposure at $650^{\circ}C$ and $870^{\circ}C$ because carbides interfere with the movement of the dislocation. It was found that the precipitation of carbide gave significant effects on the tensile properties of Hastelloy X.

Effect of Aligned Steel Fibers by a Solenoid on Flexural Fracture Behavior (솔레노이드에 의해 정렬된 강섬유가 휨파괴 거동에 미치는 영향)

  • Gyu-Pil Lee;Do-Young Moon
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.27 no.6
    • /
    • pp.193-200
    • /
    • 2023
  • This paper investigates the effect of directional alignment of steel fibers using an electromagnetic field on the flexural fracture behavior of steel fiber reinforced concrete. A specially designed and manufactured solenoid, capable of aligning steel fibers in the longitudinal direction of the beam specimen, was employed for this purpose. Beam specimens with a design strength of 30 MPa were produced, and failure tests were conducted on specimens exposed to electromagnetic fields and those without exposure. Experimental variables included the mixing ratio and aspect ratio of steel fibers. The results of the experiments revealed a slight increase in flexural strength and crack mouth opening displacement at the maximum load for specimens exposed to the electromagnetic field. Notably, a significant enhancement in fracture energy was observed.

Deterioration Properties of Shotcrete as Tunnel Supporter was Exposed to Harmful Ions (터널 지보용 숏크리트의 유해이온에 대한 열화특성)

  • Jung, Ho-Seop;Kim, Dong-Gyou
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.12 no.5
    • /
    • pp.55-64
    • /
    • 2008
  • Shotcrete have become a deterioration which was exposed to harmful environments. In this study, in order to evaluate the deterioration properties of shotcrete, visual examination, compressive strength, adhesive strength, microstructural analysis were investigated up to the 60th weeks of exposure. The attack solutions for test are sodium sulfate and hydrochloric acid solution with different concentrations, respectively. From the results, although the compressive strength of shotcrete specimens and the adhesive strength between specimens and rocks were high at the early immersion age, they rapidly dropped in the subsequent phases, especially in 5% sodium sulfate and pH1 hydrochloric acid solution. With continued exposure, various harmful ions penetrated into the shotcrete specimen, reacted with the cement hydrate, and generated expansion substances. It was verified that the shotcrete specimens suffered a serious deterioration by chemical attack.