• Advances in Traditional Medicine
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• v.8 no.4
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• pp.323-328
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• 2008

The MeOH extract of seeds of Cerbera odollam Gaertn. (Apocynaceae) was screened for its antibacterial, cytotoxic and neuropharmacological activities. The extract showed moderate anti-bacterial activity against Salmonella typhi, Streptococcus saprophyticus, and Streptococcus pyogenes. It exhibited high level cytotoxicity against brine shrimp ($LC_{50}$: $3\;{\mu}g/ml$). The extract potentiated pentobarbital induced sleeping time in mice which was further supported by the exploratory behavior test at dose of 25 mg/kg. The overall results tend to suggest the antibacterial, cytotoxic and CNS depressant activities of the extract.

• Journal of Nutrition and Health
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• v.26 no.6
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• pp.680-691
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• 1993

Rats were fed for an 8-week period a low riboflavin diet(5ug riboflavin/day) or a control diet(30ug/day) supplied either ad libitum or by pair feeding in order to study the effect of riboflavin on the metabolism of lipids and neurotransmitters. Erythrocyte glutathione reductase (EGR) and monomine oxidase(MAO) activity in the liver and brain were assayed. EGR activity coefficient in riboflavin deficient rats was significantly higher than in ad libitum controls whereas MAO activity was decreased in the deficient rats. Fatty acid composition showed a different trend in the serum, liver and brain. In the serum, the concentrations of essential fatty acids and $\omega$-3 fatty acids(eicosapentaenoic acid, docosahexaenoic acid)were decreased about 20-40% in the deficient and pair-fed than in the ad libitum controls. Brain serotonin and 5-HIAA(5-hydroxyindole acetic acid) concentrations were decreased in the riboflavin deficient rats. Learning ability measured by a water maze and exploratory activity using the open field test were not impaired in the deficient rats. These results indicate that brain lipid metabolism was protected in subclinical riboflavin deficiency, however, riboflavin deficiency affected brain serotonin content.

• Journal of the Korea Safety Management & Science
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• v.12 no.3
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• pp.283-294
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• 2010

The present paper deals with an analysis of relationship among technical human resources management as a precursor, technology innovation activity and achievements of technical innovation on the basis of preceding empirical studies on technology innovation activities of manufacturing corporations. The analysis shows that First, the technical human resources management is found to have influence upon technology innovation activity in various ways, implying that the role of technical human resources management as a key to technical innovation is most important of all to enable manufacturing companies to gain edge in competition by means of technology innovation activity; and Second, technology innovation activity exercises impacts on the achievements of exploitative technology innovation as well as on the achievements of exploratory technology innovation on the part of manufacturing industry. The above findings prove that the level of technology innovation activity may be a source for superior competitiveness of manufacturing business as a result of technology innovation performance. Manufacturing corporations, thus, need to place more weight on stepping up their executive level of technology innovation activity factors than on increasing simply the level of technical investment.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.29 no.4
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• pp.65-74
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• 2006

This research tried to grasp present condition of domestic corporation's society contribution activity and grope desirable direction of society contribution activity hereafter. As analysis result, establishment of the responsible department or human power in charge for society contribution activity is insufficient, and depend on contribution activity of simple donation than to administer program directly, result of contribution activity is not linked with corporation's purpose or result and practical use of network with similar organization for society contribution was proved by low. Desirable direction of domestic corporation society contribution activity is as following hereafter based on analysis result. First, corporation must put in good order inside system with an establishment of the responsible department for society contribution, security of human power in charge and introducing education program for training specialist. Second, corporation must select specific field with capacity that corporation is holding and improve result of society contribution activity as concentrated investment. Third, corporation must construct network with various similar groups and organizations including NPO/NGO and heighten consummativeness of society contribution activity through mutual interchange and cooperation.

• Biomolecules & Therapeutics
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• v.6 no.3
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• pp.232-241
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• 1998

This study was done to investigate whether cholic acid derivatives have anti-stress activity in various stress models. Two cholic acid derivatives, ursodeoxycholic acid (UDCA) and tauroursodeoxycholic acid (WDCA), were used. physical, psychological, chemical and environmental stress models were performed. Adrenal weight, serum glucose levels and ALP activity were elevated in restraint stress model, but this elevation was prevented by UDCA treatment. Moreover, UDCA and TUDCA inhibited exploratory and spontaneous movements in oscillation stress model. In alcohol-induced stress model, TUDCA improved rotarod performance. UDCA and TUDCA significantly reduced the involution of lymphoid organs and the increment of WBC counts in cold stress model. These findings suggest that choric acid derivatives have antistress effects in various stress models.

• Journal of Korean Society for Quality Management
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• v.44 no.1
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• pp.199-214
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• 2016

Purpose: The present study was designed to examine the casual relationships among performance and arts information service quality, initial trust, user satisfaction, reuse intention and prosumer activity in social network service(SNS). Also, we intended to explore significant factors on use performance of SNS through causal model analysis in the viewpoint of total effect. Methods: As a survey tool, questionnaire has obtained validity and reliability through literature survey, exploratory survey and pretest and sample 403 was selected. For statistical treatment of pretest and main analysis, SPSS18.0 and AMOS18.0 were employed and structural equation model was employed as analysis method. Results: Result of this study shows as follows. Two factors (precision and reciprocal action) have an effect on user satisfaction, initial trust, reuse intention and prosumer activity. We found that with an importance of initial trust, prosumer activity can be a useful and significant factor in causal relationship of SNS. Conclusion: The present study shows that two factors(precision and reciprocal action) in via of initial trust, were important factors that related companies have to emphasize to raise performance, And also we confirmed new factor 'prosumer activity' through this study. However, the present study has some limitations to be studied in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3354-3362
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• 2009

Recently, the potential of advanced studies is being highlighted that the networking activity of entrepreneurs of venture businesses influences successful foundation. Given this background, this study intends to make an exploratory study on the influence of self-efficacy of the entrepreneur's cognitive characteristic and patience with ambiguity of the psychological characteristic upon networking activity, and the components of networking activity upon entrepreneurial performance. It was tested with sample of responses to the questionnaires for 156 entrepreneurs of venture businesses which are under 3 years since they were founded. Findings of this study are as follows: First, the entrepreneur's self-efficacy was shown to have a significant effect on networking and entrepreneurial performance. Second, patience with ambiguity was shown not to have a significant effect on networking and entrepreneurial performance. Third, networking was shown to have an effect on entrepreneurial performance, and among the components of networking activity, network frequency and reliability were shown to significantly influence entrepreneurial performance, while network range was shown not to have a significant effect on it. Therefore, for performance improvement of start-up enterprises, rather self-efficacy of the entrepreneur's cognitive characteristic than the psychological characteristic seems more important. Also, with a practical suggestion that for the networking activity of entrepreneurs of venture businesses, network frequency and reliability may have a more critical effect rather on entrepreneurial performance than network range, the limitation and direction of this study are presented.

• Journal of the Korean Ceramic Society
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• v.51 no.2
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• pp.115-120
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• 2014

Quicklime(CaO) is generally obtained through the calcination of limestone, the main component of which is calcium carbonate($CaCO_3$). Quicklime generates high-temperature heat when reacting with water, forming slaked lime($Ca(OH)_2$). The industrial sectors for limestone are determined by the hydraulic activity of slaked lime, which is obtained by measuring temperature changes during the hydration reaction. Accordingly, this study examined the different crystallographic characteristics of limestone as affected by the geological origins of the regions where the limestones were produced, and how these characteristics affected hydraulic activity. Six limestone samples were collected from the Jecheon and Cheongsong areas and the hydraulic activities were measured in accordance with KS E 3077. The results indicate that limestone produced in the Cheongsong area, recrystallized through metamorphism caused by hydrothermal alteration, hada larger grain size of calcite than that of the Jecheon area, and displays a tendency of changing to marble. Limestone from the Cheonsong area showed more radical reaction in the early stage of hydration compared to that ofthe Jecheon area. In addition, it was revealed that limestone having more impurities like $SiO_2$ have lower hydraulic activity.

• Journal of Information Technology Applications and Management
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• v.19 no.1
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• pp.25-36
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• 2012

Social Commerce recently attracted the attention of academic and industry researchers. Social Commerce aims to make a transactional environment which is beneficial to three parties-social commerce service provider, buyer and seller by way of using the platform of SNS. As Social Commerce is a new technology issue, there is no existing conceptual framework, e.g. appropriate classification the business types, that help to understand the nature of Social Commerce. This study suggests one classification framework and tries to verify whether it works.

• The Korean Journal of Pharmacology
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• v.11 no.1 s.17
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• pp.55-60
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• 1975

An animal which is placed in a new environment displays a complex behavioral pattern consisting of locomotion, grooming and rearing. This behavioral pattern is influenced by endogenous and exogenous stimuli, such as hormonal secretion, level of neurohumoral transmitters, drugs and light. It is widely known that the most tranquilizers depressed spontaneous motor activity although their mechanisms of action were different, while antidepressants stimulated except imipramine which showed various action. Until the present time, the hole-board apparatus, which gives rather subjective data, has been used extensively to study the effects of drugs on general activity and exploratory behavior in mice. Recently a new apparatus for mobility measurements, called a 'Selective Activity Meter' has been introduced. This instrument supposedly produces more objective data on activity and behavior. The purpose of the present experiment was to study the influence of psychotropics on motor activity using the Selective Activity Meter. In the experiment, various psychotropic agents such as major tranquilizers(chlorpromazine, haloperidol); minor tranquilizers(meprobamate, diazepam); and antidepressants(amphetamine, imipramine) were used. In each experiment, the drug was administered to five mice and their activity was recorded. Each experiment was run five or more times and the results are based on the mean of each trial. The results are summarized as follows: 1. The group of mice treated with chlorpromazine showed markedly inhibited motor activity in comparison with controls and the inhibitory action of chlorpromazine was shown to be more intense than any of the other drugs used in the test. Haloperidol administration yielded similar results until 60 minutes, but mice showed less inhibition of motor activity than with chlorpromazine after 90 minutes. 2. In the group treated with diazepam, there was strong inhibition of motor activity until 30 minutes, but after 60 minutes the mice showed less inhibition than with chlorpromazine. In the meprobamate group, motor activity was inhibited in a manner similar to that of other tranquilizers, but the inhibition was less than that of diazepam. 3. In the group treated with imipramine, the inhibition developed gradually after ten minutes. 4. The effects of amphetamine did not appear until 30 minutes after administration, but then there was a significant increase in the motor activity.