• International Journal of Air-Conditioning and Refrigeration
• /
• v.16 no.4
• /
• pp.130-136
• /
• 2008

The refrigerant R-134a flow distributions are experimentally studied for a round header/ten flat tube test section simulating a brazed aluminum heat exchanger. Three different inlet orientations(parallel, normal, vertical) were investigated. Tests were conducted with downward flow for the mass flux from 70 to 130 $kg/m^2s$ and quality from 0.2 to 0.6. In the test section, tubes were flush-mounted with no protrusion into the header. It is shown that normal and vertical inlet yielded approximately similar flow distribution. At high mass fluxes or high qualities, however, slightly better results were obtained for normal inlet configuration. The flow distribution was worst for the parallel inlet configuration. Possible explanation is provided based on flow visualization results.

• Bulletin of the Korean Chemical Society
• /
• v.16 no.2
• /
• pp.89-95
• /
• 1995

The adsorption of methanethiol and benzenethiol on Ag(111) and Ag(100) surfaces is studied respectively, employing ASED (Atom Superposition and Electron Delocalization) method. Metal surfaces are modelled by 3-layer clusters. The corresponding thiolate anions are taken as adsorbates. The highly coordinated binding sites are most favored for both surfaces. The tilted angles of C-S axis from the surface normal are nearly zero. There's Charge transfer from adsorbate to substrate and the stretching frequency of C-S bond upon adsorption is blue-shifted from its gas phase counterpart, and its amount is the smallest at most highly coordinated site. FMO (Fragment Molecular Orbital) analysis of the system give the explanation for these results.

• Journal of Yeungnam Medical Science
• /
• v.39 no.4
• /
• pp.269-277
• /
• 2022

The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat Alzheimer disease. Compared to its relatively short history, optogenetics has developed considerably. The expression of microbial opsins in cells using genetic engineering allows specific control of cell signals or molecules. The application of optogenetics to Alzheimer disease research or clinical approaches is increasing. When applied with gamma entrainment, optogenetic neuromodulation can improve Alzheimer disease symptoms. Although safety problems exist with optogenetics such as the use of viral vectors, this technique has great potential for use in Alzheimer disease. In this paper, we review the historical applications of optogenetic neuromodulation with gamma entrainment to investigate the mechanisms involved in Alzheimer disease and potential therapeutic strategies.

• Korean Medical Education Review
• /
• v.20 no.3
• /
• pp.164-172
• /
• 2018

The aim of this study is to determine whether the 65 competencies, defined in "the role of Korean doctor, 2014", are suitable for basic medical education phase in Korea. It seeks to analyze the gap among the educational reality and expectation, assessment situation of the competencies above. We also try to define issues of the development, application and assessment phases of competency-based medical education (CBME) at individual medical schools. We designed survey tools based on the Miller's assessment pyramid (knowledge, explanation, demonstration, and performance) for each of the 65 competencies. The survey distributed to 41 medical schools in April 2015 and 38 replies were received (92.7%). Competencies that matched both the educational reality and expectation were numbers 1 (patient care), 33 (social accountability), and 49 (professionalism). However, all the other competencies ranked lower in current status than that of desirable level. 54 out of 65 competencies (83.07%) remained at the knowledge and explanation level when each competence were assessed. In the development, application, and assessment phases of CBME, common issues that medical schools commonly noted were difficulty linking competencies to curriculum preparation and student assessment, the lack of faculty's understanding, difficulty to reach consensus among faculties, and absence of teaching and learning methods and assessment tools that fits CBME. For the successful settle down of CBME, there is a need for efforts to develop the model of graduate outcomes, to share information and experience, and to operate faculty development program by the medical education communities.

• Journal of Korean Society for Atmospheric Environment
• /
• v.27 no.1
• /
• pp.63-72
• /
• 2011

This study describes the impact of positive sampling artifact caused by a filter-based sampling in the determination of ambient organic carbon (OC). Three different sampling media combinations were employed for this investigation: (1) Quartz filter-alone (Q-alone), (2) quartz filter behind quartz-fiber filter (QBQ), and (3) quartz filter and quartz filter behind Teflon filter (Q-QBT). The measurement of ambient OC was carried out at a semi-urban site near oceanside at the end of November of 2008. It was found that Q-alone sampling configuration resulted in a higher OC than QBQ and Q-QBT by 14% and 28%, respectively due to no correction for positive artifact caused by adsorption of gas-phase OC onto the filter. A lower quantity of OC was collected from the backup quartz filter on QBQ than that from Q-QBT. A possible explanation is that the front quartz filter of QBQ was not fully saturated with gas-phase OC during the sampling period, allowing smaller amount of gas-phase OC to reach the backup quartz filter. The contribution of positive artifact to $PM_{2.5}$ mass was approximately 2.15 ${\mu}g/m^3$ which is equivalent to 6% in terms of Q-QBT sampling configuration. The positive artifact was found to be more dominated during summer than during winter, showing temperature dependence. It was concluded that Q-QBT sampling configuration offers less impact of positive artifact on ambient OC sampling than QBQ in quantification of OC.

• Journal of Astronomy and Space Sciences
• /
• v.29 no.2
• /
• pp.181-189
• /
• 2012

To broaden the understanding of classical Cepheid structure, evolution and atmospheres, we have extended our continuing secret lives of Cepheids program by obtaining XMM/Chandra X-ray observations, and Hubble space telescope (HST) / cosmic origins spectrograph (COS) FUV-UV spectra of the bright, nearby Cepheids Polaris, ${\delta}$ Cep and ${\beta}$ Dor. Previous studies made with the international ultraviolet explorer (IUE) showed a limited number of UV emission lines in Cepheids. The well-known problem presented by scattered light contamination in IUE spectra for bright stars, along with the excellent sensitivity & resolution combination offered by HST/COS, motivated this study, and the spectra obtained were much more rich and complex than we had ever anticipated. Numerous emission lines, indicating $10^4$ K up to ${\sim}3{\times}10^5$ K plasmas, have been observed, showing Cepheids to have complex, dynamic outer atmospheres that also vary with the photospheric pulsation period. The FUV line emissions peak in the phase range ${\varphi}{\approx}0.8-1.0$ and vary by factors as large as $10{\times}$. A more complete picture of Cepheid outer atmospheres is accomplished when the HST/COS results are combined with X-ray observations that we have obtained of the same stars with XMM-Newton & Chandra. The Cepheids detected to date have X-ray luminosities of log $L_X{\approx}28.5-29.1$ ergs/sec, and plasma temperatures in the $2-8{\times}106$ K range. Given the phase-timing of the enhanced emissions, the most plausible explanation is the formation of a pulsation-induced shocks that excite (and heat) the atmospheric plasmas surrounding the photosphere. A pulsation-driven ${\alpha}^2$ equivalent dynamo mechanism is also a viable and interesting alternative. However, the tight phase-space of enhanced emission (peaking near 0.8-1.0 ${\varphi}$) favor the shock heating mechanism hypothesis.

• Journal of the Korean Society for information Management
• /
• v.23 no.1 s.59
• /
• pp.243-259
• /
• 2006

This paper examines the values of various library functions according to users' points of view. To execute this study, the several 'circumstance', related variables and 'condition' variables that lead to factors or functions of academic libraries were measured. Analysis was carried out in three stages. In the first, factor analysis was used on the three multi variable dimensions to ensure that the groups of variables loaded significantly and uniquely on the respective dimensions. The second phase of analysis involved the use of binary logistic regression analysis to complete research models. In the third phase, t-test was used to identify significant differences in the independent variables for additional explanation of the models. Books, competition & effectiveness and fee verses free (fee-free hereafter) are the three main factors that distinguish not only the purpose of using an academic library but also the degree of influence on knowledge, information and library facilities for the users. In addition, the fee-free factor related to digital library facilities was also uncovered.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.18 no.9
• /
• pp.687-697
• /
• 2006

The air and water flow distribution are experimentally studied for a heat exchanger composed of round headers and 10 flat tubes. The effects of tube protrusion depth as well as mass flux, and quality are investigated, and the results are compared with the previous 30 channel results. The flow at the header inlet is annular. For the downward flow configuration, the water flow distribution is significantly affected by the tube protrusion depth. For flush-mounted geometry, significant portion of the water flows through frontal part of the header. As the protrusion depth increases, more water is forced to the rear part of the header. The effect of mass flux or quality is qualitatively the same as that of the protrusion depth. Increase of the mass flux or quality forces the water to rear part of the header. For the upward flow configuration, different from the downward configuration, significant portion of the water flows through the rear part of the header. The effect of the protrusion depth is the same as that of the downward flow. As the protrusion depth increases, more water is forced to the rear part of the header. However, the effect of mass flux or quality is opposite to the downward flow case. As the mass flux or quality increases, more water flows through the frontal part of the header. Compared with the previous thirty channel configuration, the present ten channel configuration yields better flow distribution. Possible explanation is provided from the flow visualization results.

• Journal of the Korean Vacuum Society
• /
• v.7 no.3
• /
• pp.187-194
• /
• 1998

InGaAsP epitaxial layers lattice matched to InP were grown at 600 and $620^{\circ}C$ by low pressure metalorganic chemical vapor deposition. Solid phase composition of group III was controlled by the diffusion flux gas phase to the reachion surface. For the case of group V, the difference of As and P vapor pressure and pyrolysis efficiency of $PH_3$and $AsH_3$ mainly determined their in corporation into solid. An abnormal behavior of peak energy shift was observed below 75K in temperature variant photoluminescence study. This abnormal behavior was explained by the difference in order of ordering which makes spatial variation of energy gap in InGaAsP layer and this explanation was supported by the analyses of transmission electron microscopy and transmission spectroscopy.

• Applied Chemistry for Engineering
• /
• v.18 no.1
• /
• pp.71-76
• /
• 2007

We have demonstrated the resonant resistance pattern changes of the polymer film in the quartz crystal analysis by the function of the molecular polarity phase transition phenomena. PVA and PMMA/PVAc blend films were used as hydrophilic and/or hydrophbic film, respectively. In the comparison between the hydrophilic shows the pattern changes near by the phase transition temperature. For more detailed explanation, the static capacity in the oscillation parameter was measured and the morphology of Au quartz crystal electrode was studied by AFM. It is suggested that the different resonant resistance pattern change is reliable in the condition of different polarity, and the conclusion is important to analysis of the real mechanism a normal quartz crystal experiments.