• Proceedings of the Korean Statistical Society Conference
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• 2002.05a
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• pp.67-72
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• 2002

A Bayesian testing procedure is proposed for assessment of bioequivalence in both mean and variance which ensures population bioequivalence under normality assumption. We derive the joint posterior distribution of the means and variances in a standard 2 ${\times}$ 2 crossover experimental design and propose a Bayesian testing procedure for bioequivalence based on a Markov chain Monte Carlo methods. The proposed method is applied to a real data set.

• Proceedings of the IEEK Conference
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• 2002.07b
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• pp.1232-1235
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• 2002

An experiment on the automatic population measurement of brown Mealy Bugs is first reported in this article. Several image processing techniques are employed along with mapping function and neural network. Though brown Mealy Bugs are difficult to detect because of their camouflage, the experimental results showed that approximately 74% of them were correctly detected.

• The korean journal of orthodontics
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• v.25 no.6 s.53
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• pp.697-704
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• 1995

Chicken calvarial bone is known to contain various cell types, but their exact composition is unknown. By characterizing the chicken calvarial bone biochemically, it can be used to study biochemical, histochemical actions of bone cells in general. Calvaria of 18-day-old white leg horn embryo was aseptically dissected and bone cell populations were isolated by sequential enzymatic digestion. Histochemical study for osteoclast-like bone cell. population was performed with tartrate resistant acid phosphatase(TRAP) stain and for osteoblast-like bone cell population, alkaline phosphatase(ALP) stain was performed. Biochemical study for osteoblast-like bone cell population was performed using alkaline phosphatase(ALP) assay. Following conclusions were obtained from this study. 1. TRAP positive multi and mononuclear cells were mostly observed in group I and II, indicating that osteoclast-like bone cell population is mostly found in these groups. 2. All the cultured groups showed almost equal ALP activities and were positive for ALP stain, indicating that osteoblast-like bone cell population is evenly dispersed in all culture groups. 3. Experimental group treated with $1,25(OH)_{2}D_3$ showed increase in ALP activity in contrast to the control group, confirming previous studies that $1,25(OH)_{2}D_3$ increases ALP activities in in vitro bone cultures. 4. Results from von Kossa's stain indicated that in vitro bone formation had occured after 3 weeks of culture with beta-glycero phosphate.

• Korean journal of applied entomology
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• v.36 no.3
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• pp.215-223
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• 1997

A matrix model of rice weevil population based on degree day (DD) was constructed. The basic matrix model predicted on exponential jncrcase of the adult weevil density and the finite rate of increase(h) of the population was estimated to be 2.155/100DD. Adult density simulated by the matrix model including intraspecific competition showed a damped oscillation over time and reached at the stationary level of 530 at 69, 300DD. The experimental population showed similar features to that of the model. But there were some differences in the highest density and period of adult oscillation. The differences could largely be caused by the assumption of the model; resource constancy.

• Clinical and Experimental Pediatrics
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• v.64 no.12
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• pp.630-631
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• 2021

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5875-5878
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• 2012

Background: Peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) is a ligand dependent transcription factor involved in various processes, including carcinogenesis. We aimed to investigate any possible association of the $PPAR{\gamma}$ Pro12Ala (rs1801282) polymorphism with risk of developing gastric cancer (GC). Patients and Methods: A hospital based case control study was designed covering 50 patients with GC and 120 healthy controls. The frequencies of $PPAR{\gamma}$ Pro12Ala (rs1801282) were determined using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Results: The Ala12 allele of the $PPAR{\gamma}$ Pro12Ala G gene was associated with a 1.95 fold increased risk of GC development (p: 0.022; 95% CI: 1.58-2.40). Subgroup analyses showed that the same allele was also associated with metastasis (p: 0.000; OR:4.09; 95%CI:2.273-7.368) and differentiation (p: 0.004; OR:1.95; 95%CI:1.335-2.875) in patients with GC. Conclusion: This study suggests that the $PPAR{\gamma}$ Pro12Ala G (Ala12) allele might be associated with development, differentiation and metastatic process of GC in the Turkish population. Further studies conducted in larger study groups and in different ethnic populations will be needed to clarify the exact role of the $PPAR{\gamma}$ Pro12Ala polymorphism in GC.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.3
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• pp.320-324
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• 2008

We investigated the effect of ESR gene-based selection on an improvement of litter size in the herds in real (non-experimental) conditions. The pigs were selected for three years. In the tested population the pigs were mated according to a breeding scheme where the individuals with at least one ESR-B allele were preferred in the selection. In the control group (CP; n = 140) the pigs were mated just according to a breeding scheme without knowledge of the ESR genotype. We observed a significant increase in litter size (total number of born, number of born alive and number of weaned piglets per litter) in the final tested ESR-selected population (LP; n = 184) and an insignificant increase in CP as compared with the original population (OP; n = 155). After the selection we could observe a significant increase in the frequency of allele B in LP. Frequency of the genotypes AB and BB increased in both LP and CP; the distribution of the genotypes changed significantly only in LP. An association analysis of the ESR gene effects on reproductive traits in LP showed no significant differences between the genotypes. The results of our study suggest that ESR gene-based selection can be successful also in small herds, under real (non-experimental) conditions with a respect for general breeding principles and limitations and during a short period. An examination of a larger sample population as well as an analysis of selection consequences on other traits (meat and carcass quality) could bring a more conclusive evaluation of ESR-based selection. Nevertheless, the results are encouraging especially for small breeding farms taking a perspective of better litter size improvement.

• Korean Journal of Veterinary Pathology
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• v.2 no.1
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• pp.37-46
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• 1998

It has been known that $\gamma$-irradiation usually induces cell death in regenerating stem cell in normal tissues like skin, intestine and hematopoietic organ. The experiment were carried out to evaluate the early response of radiation injury in radiosensitive and intermediate radiosensitive tissues in feeding and starving rats with the doses of 3.5 and 7.0 Gy. The results of the study showed that the histological phenomenon was apoptosis in the doses of the radiation as the early response of tissue injury. Apoptosis were showed organ-specific and cellular specific responses suggesting that the selection of apoptosis be exactly focused on highly renewal organs and cells. It was interesting that the rats starved for 72 hours prior to irradiation induced less apoptosis in liver than fed rats. As for cellular responses it appeared that apoptotic cells were mostly distributed in ductal or periportal cells in liver of feeding rats unlikely in liver of Starving rots which showed no difference in zonal distribution. In salivary gland apoptotic cells in fed rats were highly induced in intercalating and ductal cell population than in acinar cell population although unlikely in starved rats. This study showed the value of apoptosis using the detection system of TUNEL for evaluating cellular damage after radiation injury and the diminished effect of starvation on cell damage after ionizing irradiation.

• Nuclear Engineering and Technology
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• v.55 no.12
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• pp.4491-4503
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• 2023

This study aimed to verify and validate the transient simulation capability of the hybrid code system RAST-F for fast reactor analysis. For this purpose, control rod (CR) drop experiments involving eight separate CRs and six CR groups in the China Experimental Fast Reactor (CEFR) start-up tests were utilized to simulate the CR drop transient. The RAST-F numerical solution, including the neutron population, time-dependent reactivity, and CR worth, was compared against the measurement values obtained from two out-of-core detectors. Moreover, the time-dependent reactivity and CR worth from RAST-F were verified against the results obtained by the Monte Carlo code Serpent using continuous energy nuclear data. A code-to-code comparison between Serpent and RAST-F showed good agreement in terms of time-dependent reactivity and CR worth. The discrepancy was less than 160 pcm for reactivity and less than 110 pcm for CR worth. RAST-F solution was almost identical to the measurement data in terms of neutron population and reactivity. All the calculated CR worth results agreed with experimental results within two standard deviations of experimental uncertainty for all CRs and CR groups. This work demonstrates that the RAST-F code system can be a potential tool for analyzing time-dependent phenomena in fast reactors.

• Korean Management Science Review
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• v.29 no.2
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• pp.21-34
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• 2012

This paper addresses a network design problem in a supply chain system that involves locating both plants and distribution centers, and determining the best strategy for distributing products from the suppliers to the plants, from the plants to the distribution centers and from the distribution centers to the customers. This paper suggests a cooperative coevolutionary algorithm (CCEA) approach to solve the model. First, the problem is decomposed into three subproblems for each of which the chromosome population is created correspondingly. Each chromosome in each population is represented as a permutation denoting the priority. Then an algorithm generating a solution from the combined set of chromosomes from each population is suggested. Also an algorithm evaluating the performance of a solution is suggested. An experimental study is carried out. The results show that our CCEA tends to generate better solutions than the previous CCEA as the problem size gets larger and that the permutation representation for chromosome used here is better than other representation.