PPAR-Gamma Pro12Ala Polymorphism and Gastric Cancer Risk in a Turkish Population |
Canbay, Emel
(National Peritoneal Organization to support Peritoneal Dissemination Treatment, Tokushukai Hospital)
Kurnaz, Ozlem (Istanbul University, Experimental Medicine and Research Institute (DETAE), Department of Molecular Medicine) Canbay, Bahar (Cerrahpasa Medical Faculty, Istanbul University) Bugra, Dursun (American Hospital, General Surgery Clinic) Cakmakoglu, Bedia (Istanbul University, Experimental Medicine and Research Institute (DETAE), Department of Molecular Medicine) Bulut, Turker (Istanbul University, Istanbul Medical Faculty, Department of General Surgery) Yamaner, Sumer (Istanbul University, Istanbul Medical Faculty, Department of General Surgery) Sokucu, Necmettin (Istanbul University, Istanbul Medical Faculty, Department of General Surgery) Buyukuncu, Yilmaz (Istanbul University, Istanbul Medical Faculty, Department of General Surgery) Yilmaz-Aydogan, Hulya (Istanbul University, Experimental Medicine and Research Institute (DETAE), Department of Molecular Medicine) |
1 | Liao SY, Zeng ZR, Leung WK, et al (2006). Peroxisome proliferator activator receptor gamma Pro12Ala polymorphism, Helicobacter pylori infection and non cardia gastric carcinoma in Chinese. Aliment Pharmacol Ther, 23, 289-94 DOI |
2 | Meirhaeghe A, Amouyel P (2004). Impact of genetic variation of PPAR gamma in humans. Mol Genet Metab, 83, 93-102 DOI |
3 | Miller SA, Dykes DD, Polesky HS (1988). Simples salting-out procedure for extracting DNA from human nucleated cells. Nucleic Acid Res, 16, 1215 DOI ScienceOn |
4 | Milne AN, Carneiro F, O'morain C, Offerhaus GJ (2009). Nature meets nurture: molecular genetics of gastric cancer. Hum Genet, 126, 615-28 DOI |
5 | Prasad KN, Saxena A, Ghoshal UC, Bhagat MR, Krishnani N (2008). Analysis of Pro12Ala PPAR gamma polymorphism and Helicobacter pylori infection in gastric adenocarcinoma and peptic ulcer disease. Ann Oncol, 19, 1299-303 DOI |
6 |
Bazargani A, Khoramrooz SS, Kamali-Sarvestani E, Taghavi SA, Saberifiroozi M (2010). Association between peroxisome proliferator-activated receptor- |
7 | Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917 DOI |
8 | Leung WK, Bai AH, Chan VY, et al (2004). Effect of peroxisome proliferator activated receptor gamma ligands on growth and gene expression profiles of gastric cancer cells. Gut, 53, 331-8 DOI ScienceOn |
9 | Michalik L, Desvergne B, Wahli W (2004) Peroxisomeproliferator-activated receptors and cancers:complex stories. Nat Rev Cancer, 4, 61-70 DOI ScienceOn |
10 | Stumvoll M, Haring H (2002). The peroxisome proliferator activated receptor gamma2 pro12ala polymorphism. Diabetes, 51, 2341-7 DOI ScienceOn |
11 | Tahara T, Arisawa T, Shibata T, et al (2008). Influence of peroxisome proliferator-activated receptor (PPAR) gamma Pro12Ala polymorphism as a shared risk marker for both gastric cancer and impaired fasting glucose (IFG) in Japanese. Dig Dis Sci, 53, 614-21 DOI |
12 | Yen CJ, Beamer BA, Negri C, et al (1997). Molecular scaning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation. Biochem Biophys Res Commun, 241, 270-4 DOI |
13 | Yin M, Hu Z, Tan D, Ajani JA, Wei Q (2009). Molecular epidemiology of genetic susceptibility to gastric cancer: facus on single nucleotide polynorphisms in gastric carcinogenesis. Am J Transl Res, 1, 44-54 |
14 |
Xu W, Li Y, Wang X, et al (2010). PPAR |
![]() |