• Title/Summary/Keyword: experimental population

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A Genetic-Based Optimization Model for Clustered Node Allocation System in a Distributed Environment (분산 환경에서 클러스터 노드 할당 시스템을 위한 유전자 기반 최적화 모델)

  • Park, Kyeong-mo
    • The KIPS Transactions:PartA
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    • v.10A no.1
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    • pp.15-24
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    • 2003
  • In this paper, an optimization model for the clustered node allocation systems in the distributed computing environment is presented. In the presented model with a distributed file system framework, the dynamics of system behavior over times is carefully thought over the nodes and hence the functionality of the cluster monitor node to check the feasibility of the current set of clustered node allocation is given. The cluster monitor node of the node allocation system capable of distributing the parallel modules to clustered nodes provides a good allocation solution using Genetic Algorithms (GA). As a part of the experimental studies, the solution quality and computation time effects of varying GA experimental parameters, such as the encoding scheme, the genetic operators (crossover, mutations), the population size, and the number of node modules, and the comparative findings are presented.

Comparative Studies on Two Fluoro-Substituted 2-Pyrazoline Derivatives with Experimental and Theoretical Methods

  • Guo, Huan-Mei;Wang, Xian;Jian, Fang Fang;Xiao, Hai Lian;Zhao, Pu Su
    • Bulletin of the Korean Chemical Society
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    • v.30 no.5
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    • pp.1061-1066
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    • 2009
  • Two fluoro-substituted 2-pyrazoline derivatives, 1-phenyl-3-(4-methoxyphenyl)-5-(4-fluorophenyl)-2-pyrazoline (1) and 1-phenyl-3-(4-methoxyphenyl)-5-(2-fluoro-phenyl)-2-pyrazoline (2) have been synthesized and characterized by elemental analysis, IR, UV-Vis and fluorescence spectra. The crystal structure of 1 has been determined by X-ray single crystal diffraction. For the two compounds, density functional theory (DFT) calculations of the structures and natural population atomic charge analysis (NPA) have been performed at B3LYP/6-311G** level of theory. By using TD-DFT method, electron spectra of 1 and 2 have been predicted, which are very approximate with the experimental ones. Comparative studies on 1 and 2 indicate that the location change of fluorine atom in 5-position phenyl ring of 2-pyrazoline does not make significant change of geometries and electronic transition bands, but it leads to evident change of atomic charge distributions and peak intensities of UV and fluorescence spectra.

An Experimental Study on Sea Water Freezing behavior in a Rectangular vessel Cooled From Above (구형용기의 상부면 냉각에 의한 해수 동결거동의 실험적 연구)

  • 최부홍
    • Journal of Advanced Marine Engineering and Technology
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    • v.22 no.4
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    • pp.529-537
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    • 1998
  • Currently as due to the rapid development of industry and increase in population we meet serious problems concerning the shortage and pollution of water. In the country many experts predict a shortage of water approaching 450 million tons by the year 2006. To cope with this serious problem it is necessary to construct desalination plants. In the adoption of a desalination system the most important factor is the cost of fresh water production,. In general LNG is stored in a tank as a liquid state below $-162^{\circ}C$. When it is serviced, however the LNG absorbs energy from a heat source and transforms to a high pressure gaseous state. During this process a huge amount of cold energy accumulated in cooling LNG is wasted. This wasted cold energy can be utilized to produce fresh water by using a sea water freezing desalination system. In order to develop a sea water freezing desalination system and to establish its design technique qualitative and quantitative data regarding the freezing behavior of sea water is required in advance, The goals of this study are to reveal the freezing behavior of sea water is required in advance. The goals of this study are to reveal the freezing mechanisms of sea water to measure the freezing rate and to investigate the freezing heat-transfer characteristics,. The experimental results will provide a general understanding of sea water freezing behavior in a rectangular vessel cooled from above.

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Immunomodulatory Effects of Hominis Placenta Extract Injection into an Acupuncture Point on the Experimental Subcutaneous Tumor Model of Mice

  • Lee, Soo-Jin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.5
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    • pp.1285-1289
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    • 2006
  • Hominis placenta (HP) has been used as an agent for promoting physiological function in traditional asian medicine. The present study was peformed to investigate whether HP acupuncture treatment in an experimental tumor mice model inhibit tumor growth through immunomodulatory effects. Mice were inoculated subcutaneously with colon26-L5 cells on the back. Three days after tumor inoculation, HP herbal acupuncture treatment was conducted on BL18 acupoint every other day for three weeks. HP Herbal acupuncture treatment significantly suppressed the primary tumor growth and prolonged survival rate. To evaluate immunomodulatory effect of HP acupuncture, splenocytes proliferation assay, fluorescence-activated cell sorting (FACS) and ELISA for IFN- ${\gamma}$, and IL-4 cytokine level. HP herbal acupuncture enhanced the mitogenic activity of Balb/c whole splenocytes induced by various mitogenic stimuli and increased immune cell population such as T cell, B cell, Th cell, Tc cell and Macrophages. HP herbal acupuncture caused a marked increase of production of Th1 cytokine (IFN- ${\gamma}$ ,) and decrease of production of Th2 cytokine (IL-4). These results indicated that HP herbal acupuncture suppresses tumor growth through a mechanism leading to a Th1 dominant immune state.

Measurement and Modeling of Personal Exposure to the Electric and Magnetic Fields in the Vicinity of High Voltage Power Lines

  • Tourab, Wafa;Babouri, Abdesselam
    • Safety and Health at Work
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    • v.7 no.2
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    • pp.102-110
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    • 2016
  • Background: This work presents an experimental and modeling study of the electromagnetic environment in the vicinity of a high voltage substation located in eastern Algeria (Annaba city) specified with a very high population density. The effects of electromagnetic fields emanating from the coupled multi-lines high voltage power systems (MLHV) on the health of the workers and people living in proximity of substations has been analyzed. Methods: Experimental Measurements for the Multi-lines power system proposed have been conducted in the free space under the high voltage lines. Field's intensities were measured using a referenced and calibrated electromagnetic field meter PMM8053B for the levels 0 m, 1 m, 1.5 m and 1.8 m witch present the sensitive's parts as organs and major functions (head, heart, pelvis and feet) of the human body. Results: The measurement results were validated by numerical simulation using the finite element method and these results are compared with the limit values of the international standards. Conclusion: We project to set own national standards for exposure to electromagnetic fields, in order to achieve a regional database that will be at the disposal of partners concerned to ensure safety of people and mainly workers inside high voltage electrical substations.

Experimental and numerical assessment of helium bubble lift during natural circulation for passive molten salt fast reactor

  • Won Jun Choi;Jae Hyung Park;Juhyeong Lee;Jihun Im;Yunsik Cho;Yonghee Kim;Sung Joong Kim
    • Nuclear Engineering and Technology
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    • v.56 no.3
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    • pp.1002-1012
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    • 2024
  • To remove insoluble fission products, which could possibly cause reactor instability and significantly reduce heat transfer efficiency from primary system of molten salt reactor, a helium bubbling method is employed into a passive molten salt fast reactor. In this regard, two-phase flow behavior of molten salt and helium bubbles was investigated experimentally because the helium bubbles highly affect the circulation performance of working fluid owing to an additional drag force. As the helium flow rate is controlled, the change of key thermal-hydraulic parameters was analyzed through a two-phase experiment. Simultaneously, to assess the applicability of numerical model for the analysis of two-phase flow behavior, the numerical calculation was performed using the OpenFOAM 9.0 code. The accuracy of the numerical analysis code was evaluated by comparing it with the experimental data. Generally, numerical results showed a good agreement with the experiment. However, at the high helium injection rates, the prediction capability for void fraction of helium bubbles was relatively low. This study suggests that the multiphaseEulerFoam solver in OpenFOAM code is effective for predicting the helium bubbling but there exists a room for further improvement by incorporating the appropriate drag flux model and the population balance equation.

Transduction of eGFP Gene to Human Embryonic Stem Cells and Their Characterization (인간 배아줄기세포로의 eGFP 유전자 도입 및 특성 분석)

  • Kim, Yoon-Young;Ku, Seung-Yup;Park, Yong-Bin;Oh, Sun-Kyung;Moon, Shin-Yong;Choi, Young-Min
    • Clinical and Experimental Reproductive Medicine
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    • v.36 no.4
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    • pp.283-292
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    • 2009
  • Objective: Human embryonic stem cells (hESCs) can proliferate indefinitely and differentiate into all kinds of cell types in vitro. Therefore, hESCs can be used as a cell source for cell-based therapy. Transduction of foreign genes to hESCs could be useful for tracing differentiation processes of hESCs and elucidation of gene function. Thus, we tried to introduce enhanced green fluorescent protein (eGFP) gene to hESCs, XX and XY cell lines in this study. Methods: Lentivirus containing eGFP was packaged in 293T cells and applied to hESCs to transduce eGFP. Expression of transduced eGFP was evaluated under the fluorescence microscope and eGFP positive population was analyzed by FACS. Expression of undifferentiation state markers such as Oct4, Nanog, SSEA4 and Tra-1-81 was examined by RT-PCR and/or immunofluorescence in eGFP-hESCs after transduction. In addition, the ability of eGFP-hESCs to form embryoid bodies (EBs) was tested. Results: eGFP was successfully transduced to hESCs by lentivirus. eGFP expression was stably maintained up to more than 40 passages. eGFP-hESCs retained expression patterns of undifferentiation state markers after transduction. Interestingly, disappearance of transduced eGFP was notably observed during spontaneous differentiation of eGFP-hESCs. Conclusion: We established eGFP expressing hESC lines using lentivirus and showed the maintenance of undifferentiation characteristics of these eGFP-hESCs. This reporter-containing hESCs could be useful for tracing the processes of differentiation of hESCs and other studies.

The Effectiveness of Bladder Training on Self Voiding after Removal of Catheter in Female Patients with Craniotomy (개두술 여성환자에게 시행한 방광훈련이 유치도뇨관제거후 자가배뇨에 미치는 효과)

  • Lee, Jung-Lim;Kim, Keum-Soon
    • The Korean Journal of Rehabilitation Nursing
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    • v.2 no.1
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    • pp.72-84
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    • 1999
  • The purpose of this study was to identify the effectiveness of bladder training on self voiding after removal of catheter in female patients with craniotomy, finally to develop a bladder rehabilitation program for cognitive impaired patients. Nonequivalent control group posttest design was used. The population of this study consisted of 34 hospitalized neurosurgical patients, all patients have been received craniotomy. 17 patients were assigned to the experimental group and another 17 patients to the control group. The homogeneity of general characteristics of the subjects was no significant difference. Bladder training program consisted of pre-training education, the bladder training, positive verbal reinforcement. The experimental group has been received bladder training and the control group has been received gravity drainage. The dependent variable, the frequency of voiding trial untill self voiding achieves, the frequency of urinary retention, the amount of residual urine, the occurrence, of urinary incontinence, were measured during 3 days after catheter removed. The data analyzed with SPSSWIN ; frequency, percentage, t-test and $X^2$-test were used to analyze homogeneity of general characteristics of subjects between the experimental and the control group. T-test, Mann-Whitney U test, and $X^2$-test were used to determine the effect of bladder training. The result of the study were as follows : There was significant difference in the frequency of voiding trial untill self voiding achieves between the experimental group and the control group. There was no significant difference in the frequency of urinary retention between the experimental group and the control group. There was no significant difference in the amount of residual urine between the experimental group and the control group. However, there was significant difference in the amount of residual urine in urinary retention patients. There was significant difference in the occurrence of urinary incontinence between the experimental group and the control group. In conclusion, bladder training program as a nursing intervention was effective in conclusion, bladder self voiding ability after removal of catheter for craniotomy patients. Therefore, it is recommended to use the bladder training program clinically for the bladder management of cognitive impaired patients.

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Continuous Water Toxicity Monitoring Using Immobilized Photobacterium phosphoreum

  • Kim, Se-Kwon;Lee, Baek-Seok;Lee, Jeong-Gun;Seo, Hyung-Joon;Kim, Eun-Ki
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.8 no.2
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    • pp.147-150
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    • 2003
  • Water toxicity monitoring based on the continuous cultivation of Photobacterium phorphoreum is presented. Normally, after 10 days of operation, a dark variant, which emits no light, appears and dominates the population, resulting in a rapid decrease in bioluminescence. Therefore, to overcome this problem, a fluidized-bed reactor is used in which alginate-immobilized cells are grown and leaking cells are continuously released into the effluent Experimental results revealed that the dominance of dark variants was suppressed inside the immobilized beads, thereby mitigating the rapid loss of bioluminescence. Plus, a high dilution rate (1.2 h$\^$-1/) prevented the occurrence of other microbial contamination in the reactor The concentration and bioluminescence of the released cells were sufficient to measure the water toxicity for more than 4 weeks.

Medical management of adults with congenital heart disease (성인 선천성 심장병 환자의 관리)

  • Kang, I-Seok
    • Clinical and Experimental Pediatrics
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    • v.49 no.9
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    • pp.937-945
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    • 2006
  • The population of adult patients with congenital heart disease(CHD) has increased dramatically because of improved survival of infants and children with CHD. There are still a substantial number of adults with unrepaired CHD. Many adult patients do not know the possible problems of their disease such as ventricular dysfunction, arrhythmia, and what they should pay attention to. They often consider themselves "cured" or "healthy" if only they don't have overt symptoms, and visit hospitals only after deterioration of their problems. Some patients are neglected because they cannot be corrected surgically although careful medical support can improve their survival and quality of life. It is, therefore, essential that the patients, their families, and physicians understand the potential problems of CHD and need for regular follow-up. In this paper we will take a brief review for common medical problems of repaired or unrepaired CHD and also mention a few specific diseases which are common in adults.