• Title/Summary/Keyword: experimental activity

Search Result 4,336, Processing Time 0.04 seconds

The Effects of Low Power Laser Treatment on Tissue Inflammatory Reactions in the Linear Incision Wound on Rat Skin (흰 쥐의 선상 절개 창상모델에서 저출력 레이저 자극이 조직 염증반응에 미치는 영향)

  • Lim, In-Hyuk;Lee, Jeong-Weon;Kim, Hyun-Sook
    • Physical Therapy Korea
    • /
    • v.10 no.2
    • /
    • pp.61-70
    • /
    • 2003
  • The purposes of this study was to evaluate the effect of low power GaAsAl laser on tissue contraction in a linear incision wound on rat skin. The linear incision wound was made on the midline of the backside in the experimental animals. Low power laser applications with different intensities such as 3, 6, or 10 mW were applied to the experimental animals twice a day for 10 days. On either the seventh or tenth postoperative day, the quantitative analysis of the inflammatory reaction surrounding the linear incision wounds on the rats were performed using enzymatical analysis of myeloperoxidase (MPO) activity. The number of neutrophil was $.07-1.0{\times}106/m{\ell}$ from a normal blood sample that was obtained from the normal experimental animals. Each concentration of neutrophil showed .04-.62 unit activity of MPO. Therefore, the 6 unit activity of MPO per neutrophil was $.57{\pm}.014{\times}10^{-6}$ unit. On the 7th and 10th post operative day, non treated tissues demonstrated increased MPO activity as compared to that of normal tissue. These data indicated that the inflammatory reaction of tissue was induced after wound induction and the MPO activity were increased in the inflammed tissues. While both 3 mW or 6 mW intensity of laser treatments did not affect the tissue MPO activity, 10 mW intensity of laser treatment significantly decreased the tissue MPO activity on the 7th and 10th post operative day. These data demonstrated that only 10 mW intensity of laser treatment successfully suppressed tissue inflammatory reaction after wound induction. In conclusion, these findings suggested that 10 mW of GaAIAs laser treatments effectively suppressed the inflammatory reaction of tissue that was induced during the wound healing process.

  • PDF

The Effects of the Situation-Based Mathematical Problem Posing Activity on Problem Solving Ability and Mathematical Attitudes (상황제시형 수학 문제 만들기(WQA) 활동이 문제해결력 및 수학적 태도에 미치는 영향)

  • Kim, Kyeong-Ock;Ryu, Sung-Rim
    • School Mathematics
    • /
    • v.11 no.4
    • /
    • pp.665-683
    • /
    • 2009
  • The purpose of this study is to improve forward mathematics study by analyzing the effects of the teaching and learning process applied situation-based mathematical problem posing activity on problem solving ability and mathematical attitudes. For this purpose, the research questions were established as follows: 1. How the situation-based mathematical problem posing activity(WQA activity) changes the problem solving ability of students? 2. How the situation-based mathematical problem posing activity(WQA activity) changes the mathematical attitudes of students? The results of the study were as follows: (1) There was significant difference between experimental group and comparative group in problem solving ability. This means that situation-based mathematical problem posing activity was generally more effective in improving problem solving ability than general classroom-based instruction. (2) There was not significant difference between experimental group and comparative group in mathematical attitudes. But the experimental group's average scores of mathematical attitudes except mathematical confidence was higher than comparative group's ones. And there was significant difference in the mathematical adaptability. The results obtained in this study suggest that the situation-based mathematical problem posing activity can be used to improve the students' problem solving ability and mathematical attitudes

  • PDF

Cation Self-Diffusin and Impurity Diffusion of Mn and Zn in CoO: (I) A comparison of the Residual Activity and the Tracer Sectioning Method

  • Lee, Jong-Ho;Martin, Manfred
    • The Korean Journal of Ceramics
    • /
    • v.4 no.2
    • /
    • pp.90-94
    • /
    • 1998
  • Self diffusion coefficients of $^{67}$Co and impurity diffusion coefficients of $^{51}$Mn and $^{65}$Zn in single crystalline CoO have been measured by applying different radioactive isotopes simultaneously. To compare the residual activity method and the tracer sectioning method we analyzed our tracer diffusion experiments by using both methods simultaneously. According to our experimental results, the diffusion coefficients obtained from both methods are identical within experimental error, demonstrating the relibility of our experimental procedures. The diffusion coefficients of all the isotopes obtained during these test experiments for the methodology are similar in magnitude and show similar dependences on oxygen partial pressure. These first observations indicate that impurity diffusion of Mn and Zn occur via a vacancy mechanism as known for self diffusion of cobalt.

  • PDF

Effects of a Geographic Experiential program on the Formation of Geographic Concepts in Young Children : Ability to Read and Represent Maps (지리적 체험활동 프로그램이 유아의 지리 개념 행성에 미치는 영향 : 지도 이해능력을 중심으로)

  • Cho, Eun Jin;Ahn, Nam Yi
    • Korean Journal of Child Studies
    • /
    • v.23 no.6
    • /
    • pp.81-101
    • /
    • 2002
  • This study examined the effects of a geographic experiential activity program on the ability to represent and to read maps(directions, perspectives, and symbols). The subjects were 44 5-year-old kindergarten children assigned to an experimental or a control group, with 22 children in each group. The geographic experiential activity program was developed and applied to the experimental group for 4 weeks. Results indicated that the experimental group was higher in reading and representing maps than the control group. Through the geographic experiential activity program, children came to be concerned about their living space, to be able to read and comprehend a simple map, and to represent a basic map with the use of directions, perspectives, and symbols.

  • PDF

Development and Effectiveness of a Program for Enhancing the Creativity of Kindergarten Children through Physical Play (신체 놀이 활동을 이용한 유아의 창의성 증진 프로그램 개발과 효과)

  • Chae, Min-A;Choi, Wae-Sun
    • Korean Journal of Child Studies
    • /
    • v.26 no.4
    • /
    • pp.71-84
    • /
    • 2005
  • Eighty-eight 5-year-old subjects were tested by the Torrance Tests of Creative Thinking, and randomly assigned to experimental(n=44) or control(n=44) groups. Developed in collaboration with kindergarten teachers, physical activity projects were based on themes from "life and health" and "life as expression" of the kindergarten curriculum. The resulting program consisting of 24 activities was applied to the experimental group for 24 sessions. Data were analyzed by mean, standard deviation, and repeated measures ANOVA. Effectiveness of the physical activity program for enhancing creativity was shown by a significant increase in mean creativity scores of the experimental group and in the sub-scores of fluency, originality, abstraction of title, elaboration, and resistance to an impetuous ending.

  • PDF

Effects of Manual Lymph Drainage on the Activity of Sympathetic Nervous System, Anxiety, Pain, and Pressure Pain Threshold in Subjects with Psychological Stress

  • Kim, Sung-Joong
    • The Journal of Korean Physical Therapy
    • /
    • v.26 no.6
    • /
    • pp.391-397
    • /
    • 2014
  • Purpose: The aim of this study was to investigate the effects of manual lymph drainage (MLD) on the activity of sympathetic nervous system, anxiety, pain and pressure pain threshold in subjects with psychological stress. Methods: Twenty-nine subjects with psychological stress were randomly assigned to experimental (MLD) and control (rest) groups. This study was performed as a controlled, randomized study using spectral analysis of electrocardiographic (ECG) activities, the State-Trait Anxiety Inventory (STAI), Visual Analogue Scale (VAS) and Pressure Pain Threshold (PPT). Results: Heart rate variability differed significantly between the experimental and control groups (p<0.05). Anxiety and pain showed positive change in both group but it were not showed statically differences. The pressure pain threshold in the upper trapezius muscle was increased in the experimental group (p<0.05). Conclusion: These findings indicate that the application of MLD was effective in reducing the activity of the sympathetic nervous system, anxiety, pain, and increasing the PPT.

The Effects of Whole Body Vibration Exercise on Balance and Lower Extremity Muscle Activity in Stroke Patients (전신진동운동이 뇌졸중 환자의 균형 및 하지 근활성도에 미치는 영향)

  • Kim, Je-Ho
    • The Journal of Korean Physical Therapy
    • /
    • v.25 no.5
    • /
    • pp.266-272
    • /
    • 2013
  • Purpose: The purpose of this study was to determine the influence of whole body vibration (WBV) exercise on balance and lower extremity muscle activity according to different intensity of vibration in stroke patients. Methods: Thirty subjects were randomly divided into three groups: experimental group II (n=10), III (n=10), and control group I (n=10). Each subject was exposed to three WBV conditions, as follows: 1. no WBV (group I), 2. 10 Hz (group II), 3. 30 Hz (group III) in semi squat position. The exercise program was conducted for six weeks (five times per week; 16 minutes per day). Subjects were measured on balance (limited of stability: LOS) and lower extremity muscle activity. Results: Significant difference in balance and lower extremity muscle activity was observed in the experimental group (II, III), compared with the control group (I). Results of post-hoc analysis, showed a significant difference in balance (LOS) in on group II and group III compared with group I, but no significant difference in on group II compared with group III, and a significant difference in lower extremity muscle activity in on group II and group III compared with group I, and a significant difference on in group II compared with group III. Conclusion: WBV exercise may be helpful in improvement of balance and lower extremity muscle activity in stroke patients.

Central nervous system activity of the methanol extracts of Caesalpinia bonducella and Bauhinia racemosa (Caesalpinaceae) in experimental animal model

  • Kumar Ramanathan Sambath;Sivakumar Thangavel;Sundaram Rajagopal Shanmuga;Gomathi Periyasamy;Kumar Mani Senthil;Mazumdar Upal Kanti;Gupta Malaya
    • Advances in Traditional Medicine
    • /
    • v.6 no.3
    • /
    • pp.221-231
    • /
    • 2006
  • The aim of the present study is to investigate central nervous system (CNS) activity of the methanol extracts of leaves of Caesalpinia bonducella (MECB) and stem bark of Bauhinia racemosa (MEBR) (Caesalpinaceae) in Swiss albino mice and Wistar albino rats. General behavior, exploratory behavior, muscle relaxant activity and phenobarbitone sodium-induced sleeping time were studied. The results revealed that the methanol extracts of leaves of Caesalpinia bonducella at 100 - 200 mg/kg and stem bark of Bauhinia racemosa 100 - 200 mg/kg caused a significant reduction in the spontaneous activity (general behavioral profile), remarkable decrease in exploratory behavioral pattern (Y-maze and head dip test), a reduction in muscle relaxant activity (rotarod and traction tests), and also significantly potentiated phenobarbitone sodium-induced sleeping time. The results suggest that MECB and MEBR exhibit CNS depressant activity in tested animal models.

Inhibition of HIV-1 Replication by the Water-soluble Extract Mixture of Ricini Semen and Coptidis Rhizoma

  • Kim, Kyong-Tai;Park, Se-Young;Hong, Eun-Kyung;Han, Yong-Bok;Kim, Jong-Bae
    • Biomolecules & Therapeutics
    • /
    • v.3 no.3
    • /
    • pp.210-216
    • /
    • 1995
  • Partially purified water-soluble extract mixture from Ricini and Coptidis (named as RIC) showed to be a potent inhibitor of human immunodeficiency virus-1 (HIV-1) replication. RIC was evaluated for in vitro anti-HIV activity using SupTl and H9 cells infected by a recombinant virus (pSVCAT) containing chloramphenicol acetyltransferase (CAT) gene substituted for nef gene in the HIV-1 genome. RIC inhibited syncytiaformation of SupTl cells with a half maximal effective concentration, $IC_{50}$/, of 2.5 $\mu\textrm{g}$/mι and showed marked inhibition of CAT activity in the infected H9 cells and also suppressed reverse transcriptase (RT) activity in the supernatant of the infected H9 culture. However, RIC did not inhibit the activity of reverse transcriptase directly when it was mixed with the enzyme or with viral particles. Berberine, one of components of RIC, also showed similar anti-HIV activity as RIC did. The data suggest that there are active ingredients which mediate anti-HIV activity in RIC.

  • PDF

Correlative Relationship between Proteinase, Phospholipase Activity and Adherence to Buccal Epithelial Cells of Experimental Strains of Candida albicans (Candida albicans의 Proteinase 및 Phospholipase 분비능과 구강상피세포 부착능과의 상호관계)

  • Koh, Choon-Myung;Kim, Soo-Ki
    • The Journal of the Korean Society for Microbiology
    • /
    • v.22 no.4
    • /
    • pp.403-411
    • /
    • 1987
  • This study investigated whether a correlation exists between proteinase activity, phospholipase activity and adherence of Candida albicans to buccal epithelial cells by using of various strains isolated from oral cavity. The proteinase activity of 30 strains was tested by culture on agar media that contained bovine serum albumin as a nitrogen source. Using the serum-protein-agar method to test proterolysis of serum albumin in 20 strains of Candida albicans. Twenty-six strains of Candida albicans were phospholipase producers and the degree of phopholipase activity of experimental strains were $0.51{\sim}0.89$ measured by Pz-value. Twenty-eight strains of Candida albicans were adhersive to buccal epithelial cells and 15 strains were foung significantly active adherence. Fifteen strains of Candida albicans were correlated with proteinase activity and adherence to epithelial cells and concomitantly 20 strains of Candida albicans were also correlated with phospholipase activity and adherence. In conclusion our investigation provides evidence of a correlation between quantitative proteinase, phospholipase and adherence. An association of these parameters may be an important contributory factor for pathogenicity.

  • PDF