• Title/Summary/Keyword: experimental activity

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The Effects of Transcutaneous Electrical Nerve Stimulation on Sympathetic Nerve Activity in Delayed Onset Muscle Soreness (경피신경전기자극이 지연성근육통의 교감신경활동에 미치는 영향)

  • Park, Jang-Sung
    • The Journal of Korean Physical Therapy
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    • v.14 no.1
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    • pp.109-115
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    • 2002
  • This study conducts eccentric exercise ti non-dominant elbow flexor of 20 persons in order to examine the effects of transcutaneous electric nerve stimulation on sympathetic nerve activity in delayed onset muscle soreness, induces delayed onset muscle soreness, divides them into 10 persons respectively as experimental and control groups. And a stimulation for 2 min. with 100 pps is given to elbow flexor after repeated three times of 10 minutes rest, temperature, blood pressure and pulse are measured and as a result of two-way ANOVA, change of temperature didn't show a significant difference according to the elapse of times(p>0.05) and systolic pressure and pulses in showed a significant difference between experimental and control groups(p<0.05). These results suggest that transcutaneous electrical nerve stimulation has a direct or indirect influence on sympathetic nerve activity in delayed onset muscle soreness under a restricted condition of electrical stimulation.

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In vivo Efficacy of LB20304a against Experimental Respiratory Tract Infection in Mice (생쥐의 호흡기 감염에 대한 퀴놀론계 항생제 LB20304a의 치료 효과)

  • An, Mi-Jeong;Kim, Mu-Yong;Baek, Gyeong-Suk;Kim, In-Cheol;Gwak, Jin-Hwan
    • YAKHAK HOEJI
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    • v.40 no.4
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    • pp.438-441
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    • 1996
  • The therapeutic activity of LB20304a was examined on experimental respiratory tract infection (RTI) caused by Klebsiella pneumoniae DT-S in mice. A single oral dose of LB 20304a (1.2mg/mouse) showed a rapid bacteriocidal activity in lung tissue at 4,7 and 24h after administration of drug. The in vivo activity of LB20304a was comparable to that of ciprofloxacin against K. pneumoniae infection, although in vitro MIC of LB20304a was four-fold higher than that of ciprofloxacin.

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Isolation of Isoguanosine from Croton tiglium and Its Antitumor Activity

  • Kim, Jung-Han;Lee, Sang-Jun;Han, Young-Bok;Moon, Jung-Jo;Kim, Jong-Bae
    • Archives of Pharmacal Research
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    • v.17 no.2
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    • pp.115-118
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    • 1994
  • This paper describes the isolation of isoguanosine from Croton tiglium L. and its cytotoxic effect anginst several tumor cell lines in culture and newly reports that isoguanosine has an antitumor activity against implanted S-180 ascitic turmor mice. Isoguanosine is effective at the dose of $24mg/kg/day{\times}5$, with T/C value of 168%. Isoguanosine inhibits the gorwth of S-180 and Ehrich solid tumor in mice at the optimal doses of $96\; mg/kg/day{\times}12$ and $48\;mg/kg/day{\times}12$, with 1-T/C values of 65% and 60% respecively.

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Activity Coefficients of Uni-univalent Electrolytes in Anhydrous Ethylenediamine (에틸렌디아민 非水溶液中에서의 1:1 염의 活性係數)

  • Joon Yong Kim
    • Journal of the Korean Chemical Society
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    • v.17 no.4
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    • pp.229-234
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    • 1973
  • The dependence of ionic activity and electrode potential upon electrolyte concentration in ethylenediamine includes the effects of ion-pair formation involving all possible combinations of cations and anions represent in the solution and includes the ion-atmosphere effects of dissociated ions. For calculating activity coefficients, Debye-Huckel limiting law, extended Debye-Huckel,equation, and Marshall Grunwald equation were used in comparison of experimental and calculated plots of the electromotive force of the cell versus the logarithum of concentration. The fit of the experimental points to the theoretical curves was improved in case of the Marshall-Grunwald equation.

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Immunomodulating Activity of BL18 (Ganshu) Acupuncture on the Experimental Liver Metastasis Model of Mice

  • Kim, Myoung-Dong;Kim, Sung-Hoon;Lee, Soo-Jin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.3
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    • pp.760-764
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    • 2007
  • We investigated that the immunomodulating activity of BL18 (Ganshu) acupuncture on the experimental liver metastasis model of mice. NA (non-acupoint)- and BL18-treatment enhanced the mitogenic activity of BALB/c whole splenocytes induced by various mitogenic stimuli. Acupuncture treatment tended to increase splenocytes differentiation even though did not show significance. Acupuncture treatment caused a marked increase of production of Th1 cytokine (IFN-${\gamma}$) and Th2 cytokine (IL-4) by splenocytes and IL-12 and IFN-Y by macrophages. The increase of cytokine production on BL18-treated group was more pronounced compared to NA-treated group. The liver weight of NA- and BL18-treated group decreased compared to tumor group, but did not showed significant differences.

Intrinsic Motivation as a factor Affecting Exertion in Purposeful versus Nonpurposeful Activity (목적있는 활동과 목적없는 활동간의 내적 동기화에 관한 연구)

  • Ahn, Duk-Hyun
    • Physical Therapy Korea
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    • v.1 no.1
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    • pp.25-34
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    • 1994
  • This study investigated the hypothesis that purposeful activity is an intrinsic motivator. Affecting exertion during the performance of purposeful and nonpurposeful activity was studied in 30 elementary school students. The subjects acted as their own controls in the performance of other exercise. The three experimental exercises were jumping rope, defined as a nonpurposeful activity, and jumping rope with reinforcement, defined as purposeful activity I, and jumping rope with double reinforcement (food), defined as purposeful activity II. Duration and cessation of exercise were entirely controlled by the subject. The number of jumps were measured immediately after cessation of exercise and duration of exercise in seconds by observer. The results were as follows : 1. There was a significant difference in the required time of performance between purposeful and nonpurposeful jumping (p< .05). 2. There was a significant difference in the number of jumps between nonpurposeful and nonpurposeful jumping after reinforcement. (p< .05). Implications for practice and further research are discussed.

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Effects of Peer Mentoring Program on the Health Conservation in Elderly Women with Osteoarthritis (동료멘토링 프로그램이 골관절염 여성노인의 건강보존에 미치는 효과)

  • Nam, Jiran;Sung, Kiwol
    • Research in Community and Public Health Nursing
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    • v.28 no.3
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    • pp.227-239
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    • 2017
  • Purpose: The purpose of this study was to investigate the effects of peer mentoring program on physical activity, knee joint function, self-care agency and social support, which are health conservation elements in elderly women with osteoarthritis. Methods: This study used a quasi-experimental research design. It is a pretest-and-post 1, post 2 test design of a non-equivalent control group. The subjects were elderly women aged over 65 who were diagnosed with osteoarthritis. A total of 60 patients (experimental group 30, control group 30) who registered with the Senior Welfare Center in City G and in Region D participated in this study. The data were collected from June 29th to September 4th, 2015. The collected data were analyzed with $x^2$ test, Fisher's exact test, independent t-test and repeated measurement ANOVA. Results: The experimental group showed a greater increase in physical activity, knee joint function, self-care agency and social support than the control group. Conclusion: The results indicated that the peer mentoring program is effective in increasing physical activity, knee joint function, self-care agency and social support of elderly women with osteoarthritis.

The Effects of Elementary Science Lessons Emphasizing Social Interactions on the Metacognition, Learning Motive and Academic Achievement (사회적 상호 작용을 강조한 초등 과학 수업이 메타인지, 과학 학습 동기, 학업 성취도에 미치는 영향)

  • Bae, Jin-Ho;Ok, Soo-Kyoung
    • Journal of Korean Elementary Science Education
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    • v.28 no.4
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    • pp.519-528
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    • 2009
  • The purpose of this study was to investigate the effect of social interaction on metacognition, learning motive and academic achievement in elementary science learning. The science lessons emphasizing social interactions that is applied to this study was comprised of 5 stages, 'introduction', 'inquiry activity', 'small group emergent activity', 'large group emergent activity', 'conclusion and assessment'. The results of this study were as follows: First, applying the learning model emphasizing social interaction to the experimental group led to a significant difference between the result of the pre- and post-test, regarding metacognition, especifically those of declarative knowledge. And meaningful difference was drawn from the results of all elements in the lower category of regulation of cognition between the experimental and comparison group. Second, a significant difference was found between the pre- and post-test regarding learning motive, especially those of attention, relation, and self-confidence. Third, after applying the learning model emphasizing social interaction to the science classes of the experimental group, students' academic achievement improved significantly in the post-test, compared to the results of pre-test.

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Effect of Medium and Long Chain Triglyceride Diets on the Serum Enzyme Activity in the Rats (MCT와 LCT가 혈청(血淸)의 효소활성(酵素活性)에 미치는 영향(影響))

  • Cho, Chung-Soon
    • Journal of the Korean Applied Science and Technology
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    • v.4 no.2
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    • pp.57-62
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    • 1987
  • To investigate the effect of feeding rats medium-chain triglyceride(MCT), triglyceride containing primarily $C_8$ and $C_10$ fatty acids, it were compared to the effects of feeding triglycerides composed of long-chain triglyceride (LCT), corn oil and lard, on the serum enzyme activity. For 4 weeks rats fed a diet containing 20% MCT or LCT ${\cdot}$ MCT, as compared with LCT, had the following effects: 1) The total lactic dehydrogenase(LDH) activities in the serum of all experimental group were significantly decreased then those of control group. 2) The activities of glutamic oxaloacetic transaminase (GOT) in the serum of all experimental group were decreased than those of control group. 3) The activities of glutamic pyruvic transaminase (GPT) in the serum of all experimental group were decreased, MCT and LCT group were singinficantly decreased than of control group. 4) The activities of ${\alpha}-amylase$ in the serum of all groups were significantly increased than those of control group. 5) According to electrophoresis, LDH of LDH isoezyme activities in MCT and Lard group were increased with those of $LDH_5$ in corn oil group were increased than those of control gourp. It is suggested that the MCT and LCT fed to rats influence on the activity of various serum enzymes.

Natural Anthraquinone Derivatives from a Marine Mangrove Plant-Derived Endophytic Fungus Eurotium rubrum: Structural Elucidation and DPPH Radical Scavenging Activity

  • Li, Dong-Lil;Li, Xiao-Ming;Wang, Bin-Gui
    • Journal of Microbiology and Biotechnology
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    • v.19 no.7
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    • pp.675-680
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    • 2009
  • There is considerable interest in the isolation of potent radical scavenging compounds from natural resources to treat diseases involving oxidative stress. In this report, four new fungal metabolites including one new bisdihydroanthracenone derivative (1, eurorubrin), two new seco-anthraquinone derivatives [3, 2-O-methyl-9-dehydroxyeurotinone and 4, 2-O-methyl-4-O-(${\alpha}$-D-ribofuranosyl)-9-dehydroxyeurotinone], and one new anthraquinone glycoside [6,3-O-(${\alpha}$-D-ribofuranosyl)-questin], were isolated and identified from Eurotium rubrum, an endophytic fungal strain that was isolated from the inner tissue of the stem of the marine mangrove plant Hibiscus tiliaceus. In addition, three known compounds including asperflavin (2), 2-0-methyleurotinone (5), and questin (7) were also isolated and identified. Their structures were elucidated on the basis of spectroscopic analysis. All of the isolated compounds were evaluated for 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity.