• 대한간호학회지
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• 제50권1호
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• pp.52-65
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• 2020

Purpose: To examine the effects of a smartphone application-based exercise program on self-efficacy expectations (SEE) and outcome expectations regarding exercise (OEE), physical fitness, activity level, physiological indices, and health-related quality of life in a sample of hemodialysis patients. Methods: A quasi-experimental control group pre-test post-test design was used. Subjects were recruited from two university hospitals in G city. The subjects were assigned randomly by coin toss: 33 participants to the experimental group and 30 to the control group. A literature review and the self-efficacy theory were used to develop the smartphone program. Experts designed and verified the program to be userfriendly and in consideration of user interaction. Data were collected through a self-report pre-test post-test questionnaire and online medical records. Results: In the experimental group, the levels of physical fitness and physical activity were significantly improved post-test, but the scores on health-related quality of life and the physical indices did not improve. In the experimental group, the SEE and OEE post-test scores were also significantly higher than the pre-test scores, but the control group's scores did not change. Conclusion: The smartphone application-based exercise program based on self-efficacy theory significantly improved the level of physical fitness and activity, SEE, and OEE for hemodialysis patients. The use of this application-based exercise program for hemodialysis patients might be an effective nursing intervention tool for improving SEE, OEE, level of physical fitness, and physical activity.

• 치과방사선
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• 제20권1호
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• pp.53-62
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• 1990

This experiment was performed to clarify the effects of /sup 60/Co gamma irradiation on secretory function, amylase activity and contents of nucleic acids of parotid gland in rat. Experimental animals were divided into 6th hours, 3rd, 7th, 14th and 28th days after irradiation and control. The experimental animals are singly irradiated with 20Gy (2,000rad) through protective lead block. Secretory function of parotid gland was evaluted by uptake and clearance of /sup 99m/TcO₄. /sup 99m/TcO₄. 0.2μ ci/gm, was injected into peritonium in uptake groups. Rats were sacrified with cervical dislocation after 30 minutes and gland was excised. In the clearance group. pilocarpine nitrate (8㎎/㎏) was intraperitoneally injected at 30 minutes after /sup 99m/TcO₄ injection and rats were sacrified 30 minutes after pilocarpine injection. Radioactivity of excised parotid gland was measured by using of gamma counter and stimulation-secretion coefficients, uptake radioactivity divided by clearance radioactivity, was calculated. Amylase activity and contents of DNA and RNA were determined by spectrophotometry. The results obtained were as follows: 1. In the uptake test, the radioactivity of /sup 99m/TcO₄ per unit weight increase in experimental group except 6th hours group, compared with control groups and showed a peak at 3rd days after irradiation. 2. In the clearance test, the radioactivity of /sup 99m/cO₄per unit weight rose to a peak at 3rd days after irradiation and gradually recovered thereafter. 3. Stimulation-secretion coefficient of parotid gland decreased at 6th hours, 3rd and 7th days after irradiation, and gradually increased. 4. Amylase activity of parotid gland decreased in 3rd and 7th days group, and especially lowest in 3rd days after irradiation. 5. The contents of DNA showed no definite difference in all the experimental groups, but RNA was seemed to decrease with time after irradiation.

• 한방재활의학과학회지
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• 제29권4호
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• pp.1-14
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• 2019

Objectives The object of this study was to assess the effect of Gyejibokryunghwan (GBH) on anti-oxidant and anti-inflammatory activities in RAW 264.7 cells and on factors associated with fracture union in tibia-fractured rats. Methods The 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activity was measured to assess anti-oxidant activity. The production of nitric oxide (NO), interleukin-6 (IL-6), interleukin-$1{\beta}$ ($IL-1{\beta}$) and tumor necrosis factor-${\alpha}$ ($TNF-{\alpha}$) in the RAW 264.7 cells were measured to assess anti-inflammatory activity. The production of osteocalcin, calcitonin, carboxy-terminal telepeptides of type II collagen (CTXII), transforming growth factor-${\beta}$ ($TGF-{\beta}$), bone morphogenetic protein-2 (BMP-2) in serum of tibia-fractured rats were measured to assess the effects of fracture union. X-rays were taken every two weeks from 0 to 4th week to assess fracture union effect. Results DPPH radical scavenging activity of GBH was increased according to concentration of GBH in RAW 264.7 cell. NO, prostaglandin $E_2$ ($PGE_2$), IL-6, $IL-1{\beta}$ and $TNF-{\alpha}$ were significantly decreased, indicating anti-inflammatory effect. Osteocalcin, calcitonin, $TGF-{\beta}$ were significantly increased in the experimental groups. CTXII was significantly decreased in the experimental groups. BMP-2 was not significantly changed in the experimental groups. The X-ray showed that the experimental group has better healing effects on tibia-fractured rats than control group. Conclusions From above result, GBH has an effect on anti-oxidant, anti-inflammatory activities in RAW 264.7 cells. GBH showed significant results in factors related with fracture union and radiologic examination. In conclusion, GBH can help fracture union and it well be expected to be used actively in clinics.

• 대한물리의학회지
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• 제17권3호
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• pp.59-67
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• 2022

PURPOSE: This study examined the effectiveness of task gait exercise combined with self-observation training to provide basic clinical data by analyzing the factors that task gait exercise combined with self-observation training has on the leg muscle activity and gait improvement in stroke patients. METHODS: The subjects were assigned randomly to experimental Group I, which mediated task gait exercise combined with self-observation training, and experimental Group II, which mediated task-walking movement. They received 30-minute interventions three times a week for four weeks. The leg muscle activity and 10 m walking test (10MWT) were conducted as pre-intervention tests, and they underwent a post-test four weeks later in the same manner as the pre-test. RESULTS: A statistically significant difference was observed in all muscles and 10MWT (p < .01) in experimental group I (p < .05), while there were significant differences only in the rectus femoris, biceps femoris, and 10MWT (p < .05). In a comparison of the changes between groups, there were statistically significant differences only in the tibialis anterior, soleus muscle, and 10MWT (p < .05). CONCLUSION: Self-observation training in experimental group I was effective in increasing the leg muscle activity and improving walking speed by discovering and correcting incorrect movements and following a normal gait pattern using the ankle joint. Therefore, the task gait exercise combined with self-observation training should be introduced and actively utilized for the rapid social recovery of stroke patients.

• 한국식품영양학회지
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• 제36권1호
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• pp.25-32
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• 2023

To increase antioxidant activity and physicochemical quality characteristics, four kinds of berries (blueberry (BEB), blackberry (BKB), cranberry (CNB), raspberry (RSB)) with antioxidant activities were used to replace beet (B) in existing ABC juice. In the experimental group, the pH was decreased while the content of soluble solids was increased significantly. Total polyphenol content was significantly increased in all experimental groups compared to that in the control group. The control group had the lowest polyphenol content at 14.723 ㎍ GAE/g, whereas the blackberry replacement group had the highest polyphenol content at 67.12 ㎍ GAE/g. The total flavonoid content was the lowest in the control group at 8.98 ㎍ QE/g but the highest in the blackberry group at 50.47 ㎍ QE/g. All experimental groups showed significantly higher antioxidant activities than the control group. DPPH & ABTS radical scavenging activities were the lowest in the control group at 15.69% and 19.55%, respectively, but the highest in the blackberry group at 48.24% and 59.43%, respectively. SOD-like activity was also the lowest in the control group at 14.12%, but the highest in the blackberry group at 48.18%. When comparing experimental groups, antioxidant activities (DPPH, ABTS, SOD) and antioxidant components (total polyphenols and total flavonoids) were in the order of BKB > CNB > RSB > BEB > Control. In conclusion, the new ABC juice containing four types of berries is enriched in antioxidants with significantly improved antioxidant activities and physicochemical quality characteristics.

• 대한물리의학회지
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• 제19권2호
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• pp.91-98
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• 2024

PURPOSE: This study aimed to provide basic clinical data by investigating the impact of Activities of daily living-related dual-task intervention on lung function, balance, and Activities of daily living of stroke patients. METHODS: After sampling 40 stroke patients who met the selection criteria, this study randomly assigned 20 patients who received dual-task exercise intervention to the experimental group and 20 patients who received single exercise intervention to the control group by drawing lots. Next, the study pre-tested their lung function, balance, and activity of daily living. All interventions were conducted for 30 minutes, 3 times a week for 4 weeks, and when all interventions were completed after 4 weeks, lung function, balance, and activity of daily living were re-measured in the same way as the pre-test. RESULTS: In comparing changes in lung function, balance, and activity of daily living within each of the experimental and control groups, statistically significant improvement were found in the experimental group only (p < .01). Statistically significant improvement were also found in lung function, balance, and activities of daily living between the groups (p < .05) (p < .01). CONCLUSION: A statistically significant improvements were found in lung function, balance, and activities of daily living only in the experimental group and statistically significant differences were found between groups. Because they take arm exercises by maintaining balance in a standing position on a labile surface and through dual-task exercise such as folding a towel, moving a cup, and throwing and catching a ball, muscles related to lung function were stimulated and lung function and balance were improved. This helped activities of daily living to be improved. Thus, it is considered that dual-task exercise should be utilized for stroke patients' smooth everyday life.

• Preventive Nutrition and Food Science
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• 제12권1호
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• pp.16-22
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• 2007

In order to evaluate the hepatoprotective effect of an herb distillate, ie., a mixture of 28 traditional Korean herbs, germanium, tormarine and Gijangsoo (Gijang water), $CCl_4$ was intraperitoneally administered to rats before or after supplementation of the diluted herb distillate (HD) for 2 weeks. Then hepatic xanthine oxidase activity and serum lipid profiles were determined. The experimental groups had higher feed intake than the normal control (NC), but had lower weight gain. Water intake and the amount of feces were not significantly different, but urine was excreted in lower amounts in all the experimental groups compared to the NC. Liver weights in the HD-supplemented groups were lower than that of the distilled water-supplemented groups (DW-groups) after $CCl_4$-administration. Serum ALT activities in all the experimental groups were higher than that of the NC-group. However, the increasing activity of serum ALT in the HD-supplemented groups (HD-groups) was lower than that of the DW-groups. Total serum and LDL-cholesterol levels were higher in all the $CCl_4$-administered groups than in the NC-groups, and serum HDL-cholesterol levels were lower in all the experimental groups compared with the NC-groups. Meanwhile, the increasing rate of total serum and LDL-cholesterol levels and the decreasing rate of HDL-cholesterol in the HD-groups were lower than that of the DW-groups. But, levels of serum TG were similar among all the experimental groups. The activities of hepatic xanthine oxidase (XOD) type O of the $CCl_4$-administered rats showed a significant increase in and an increasing rate of XOD in the HD-groups, which was lower than that of the DW-groups. On the other hand, GST activities in all the experimental groups were significantly decreased, and the decreasing rate was lower in the HD-groups than in the DW-groups. The hepatic contents of GSH and LPO in all the rats were not changed by $CCl_4$ administration. These results suggest that the decreased liver damage in the HD-supplemented groups was due to the inhibition of XOD-type O activity by constituents of HD, as well as by a prevention/inhibition of serum lipid profile changes in $CCl_4$-treated rats. However, further detailed studies are needed to support this hypothesis.

• 대한공업교육학회지
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• 제45권2호
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• pp.1-20
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• 2020

이 연구의 목적은 화학공업을 공부하는 학생들이 액위제어를 쉽게 이해할 수 있도록 하기 위해, 조립형 액위제어 실험장치를 제작하고 이를 수업에 적용할 수 있는 체험활동과제를 개발하는 것이다. 이를 위해 2015 개정 교육과정 화학공업 실무과목에서 액위제어와 관련된 내용요소를 분석하여, 조립형 액위제어 실험장치를 활용하는 체험 활동과제를 개발하여 전문가 검증을 마친 후, 16차시의 체험활동과제를 S 마이스터고등학교 학생 19명에게 적용하였다. 이 연구에서 얻은 결과는 다음과 같다. 첫째, 기존 완성형 액위제어 실험장치를 분석하고, 이를 토대로 학생 수준에서 조립 가능하며 실습에 활용할 수 있는 새로운 조립형 액위제어 실험장치를 설계·제작하였다. 둘째. 2015 개정 교육과정의 NCS기반 '화학공정유지운영' 실무과목의 내용을 분석하여 액위제어와 관련된 학습 내용들을 추출하였다. 이 액위제어 관련 내용 중에서 공정 흐름도의 이해, 액위제어 실험장치 제작, 유량 측정, 액위제어 현상 확인 등의 실습을 위 조립형 액위제어 실험장치로 진행하여 액위제어 관련 내용을 체계적으로 학습할 수 있도록 하였다.

• Journal of Nutrition and Health
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• 제27권9호
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• pp.892-900
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• 1994

A variety of important roles for branched-chain amino acids in metabolic regulation has been suggested. Branched-chain $\alpha$-keto acid dehydrogenase(BCKAD) complex is a rate limiting enzyme in branched-chain amino acid metabolism. The purpose of this study was to examine the effects of exercise on the activity and activity state of branched-chain $\alpha$-keto acid dehydrogenase in rat hert and liver thssues. Forty-eight Sprague-Dawley rats were assigned into three experimental groups : sedentary control, exercised, or exercised-rested. Submaximal exercise(running) for two hours significantly increased basal activity without a change in total activity in both tissues, with a concomitiant increase in activity state of the enzyme complex. At 10 min post-exercise, heart enzyme activity significantly decreased, though not to the control level, while liver enzyme activity remained unchanged. These data suggested that the exercise-induced increase in branched-chain $\alpha$-keto acid decarboxylation in rat tissues may not be the result of enzyme synthesis, but rather is due to increased activity of the BCKAD.

• 초등상담연구
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• 제9권1호
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• pp.95-110
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• 2010

본 연구는 또래 칭찬활동 프로그램이 초등학생의 교우관계와 학급응집성에 미치는 영향을 알아보기 위하여 실시되었다. 서울특별시에 소재한 J초등학교 5학년 2개 학급을 실험집단과 통제집단으로 나누어 실험집단에 프로그램을 처치하고 사후검사와 추후검사를 실시하여 프로그램의 효과를 검증하였다. 프로그램의 타당도를 검증하기 위하여 예비 실시를 통해 미비점과 문제점을 보완하였다. 연구 결과 또래 칭찬활동프로그램을 처치한 실험집단은 교우관계와 학급응집성에서 모두 유의미한 효과가 나타났으며, 아동 소감과 연구자의 관찰에서도 이 프로그램을 통해 아동의 교우관계가 개선되고, 학급응집성이 증가한 것을 알 수 있었다. 그러나 통제집단에서도 학기 초 아동의 학급생활 적응으로 인해 교우관계의 일부 하위변인에서 유의미한 효과가 나타났으며, 추후검사에서 실험집단 아동의 교우관계 하위변인 중 일부에서 효과가 감소한 것이 드러나기도 하였다. 학급응집성은 사후검사보다 추후검사에서 더욱 유의미하게 증가한 점으로 보아 본 연구에서 실시한 또래 칭찬활동 프로그램은 학급응집성의 증가와 유지에 긍정적인 영향을 미친다는 것을 알 수 있었다. 앞으로의 연구에서는 교우관계를 지속적으로 높이기 위한 프로그램의 내용 수정이나 추후지도에 관한 연구가 필요하다고 본다.