• Title/Summary/Keyword: exogenous factors

Search Result 282, Processing Time 0.03 seconds

A Study on the Pathogenic Factors and Treatments of Exogenous Febrile Disease with Time (외감열병(外感熱病)의 원인(原因)과 치법(治法)에 대한 통시적(通時的) 고찰(考察))

  • Yang, Kwang-Yeol
    • Journal of Korean Medical classics
    • /
    • v.21 no.1
    • /
    • pp.295-302
    • /
    • 2008
  • Until the middle of the 20th century, exogenous febrile disease was the most common disease that threatened the human health. For a long time, oriental medicine doctors developed many ways to cure this disease by studying pathogenic factors. The phthogenic factors and treatments of exogenous febrile disease with time are as followings. "Naegyeong(內經)" : Cold pathogen. Diaphoretic therapy, purgation therapy. Hwata : Cold pathogen. Diaphoretic therapy, emetic therapy, purgation therapy. Jangjunggyeong(張仲景) : Cold pathogen. Eight principal therapeutic methods except diaphoretic therapy with pungent and cool properties. Yuhagan(劉河間) : Fire pathogen. Diaphoretic therapy with pungent and cool properties. Idongwon(李東垣) : Improper diet and overstrain. Reinforcing therapy. Ouga(吳又可) : Epidemic pathogenic factors. Diaphoretic therapy with pungent and cool properties, Heat-reducing therapy. purgation therapy Seopcheonsa(葉天士) : Warm pathogen. diaphoretic therapy, Heat-reducing therapy, expel Heat therapy, cooling the blood and eliminating stagnation of blood. Oguktong(吳鞠通) : Six pathogenic factors. Eight principal therapeutic methods including diaphoretic therapy with pungent and cool properties.

  • PDF

Analysis of the Causal Relationships Among the Factors that Influence the Use of Mobile Phone Services (국내 이동전화 서비스 이용에 영향을 미치는 요인에 관한 연구)

  • Suh, Bo-Mil;Wee, Kyeong-Woo;Yoo, Jin-Soo
    • Journal of Information Technology Services
    • /
    • v.6 no.1
    • /
    • pp.47-63
    • /
    • 2007
  • A lot of researchers have been interested in the factors influencing the use of mobile phone services. Most of the previous studies, however, verified only the research models developed by the authors. They did not consider which model agrees better with the real situation. This study presents six alternative models based on various previous studies, and compares the data fitness of the models. A Web survey of mobile phone users collected 2,217 cases. Statistical analyses, using SEM (Structural Equation Modeling), show that the fitness of the simplest alternative model is better than that of any other model. The simplest model has no causal relationship among exogenous factors, and proposes that all of exogenous factors have direct impacts on the customer satisfaction. In addition, the analyses say that corporate and brand image and additional service are more important than the other exogenous factors such as communication quality.

Success Factors for ERP System Performance (ERP시스템의 성과에 영향을 미치는 요인 : 사용자 관점)

  • 박동진;추교완;문홍태;신기영
    • The Journal of Information Systems
    • /
    • v.12 no.1
    • /
    • pp.47-66
    • /
    • 2003
  • This study was examined the relationship between the exogenous and endogenous variables in our model to measure ERP system performance using path analysis. The exogenous variables are system quality, user participation, user training, top management support and self-efficacy, and the endogenous variables are system usage, user satisfaction, and work efficiency. The results of the study are shown as follows. First, all the exogenous variables in our model have a direct effect on user satisfaction, and system quality, training, and self-efficacy have a direct effect on system usage. Second, system usage has a direct effect on user satisfaction and user satisfaction has a direct effect on work efficiency. The findings show that the exogenous variables in the model are important to increase ERP implementation success.

  • PDF

The Effect of Exogenous Risks Upon the Choice of Real Options in ERP Projects in Korea: An Empirical Approach (ERP 프로젝트의 외생위험이 실물옵션 선택에 미치는 영향에 대한 실증 연구: 국내 ERP 프로젝트를 중심으로)

  • Nam, Seunghyeon;Kim, Taeha;Yang, Heedong
    • The Journal of Information Systems
    • /
    • v.22 no.3
    • /
    • pp.43-58
    • /
    • 2013
  • This work investigates factors that may affect the choice of real options by ERP project managers. Financial theory suggest that these factors include risk-free interest rate, time to maturity, volatility of net present value, and options exercise price. Other than these factors, we are interested in the exogenous risks related to external uncertainties about technological cost, user learning and consulting, and so forth and we argue these risks should have a significant impact upon the volatility of net present value. To validate these factors empirically, we collected survey questionnaires from ERP project managers in Korea. We find that perceived exogenous risks with regard to ERP projects influence volatility and additionally find that ERP project managers prefer contract options of the project when the volatility of the project is expected to be high. We expect that this work will not only validate theoretical propositions but help project managers consider ERP options strategically based on these factors.

SLC3A2 and SLC7A2 Mediate the Exogenous Putrescine-Induced Adipocyte Differentiation

  • Jin, Eom;Juhyun, Choi;Sung-Suk, Suh;Jong Bae, Seo
    • Molecules and Cells
    • /
    • v.45 no.12
    • /
    • pp.963-975
    • /
    • 2022
  • Exogenous polyamines are able to induce life span and improve glucose homeostasis and insulin sensitivity. However, the effects of exogenous polyamines on adipocyte differentiation and which polyamine transporters mediate them have not been elucidated yet. Here, we identified for the first time that exogenous polyamines can clearly stimulate adipocyte differentiation through polyamine transporters, solute carrier family 3 member A2 (SLC3A2) and SLC7A1. Exogenous polyamines markedly promote 3T3-L1 adipocyte differentiation by increasing the intracellular lipid accumulation and the expression of both adipogenic and lipogenic genes in a concentration-dependent manner. In particular, exogenous putrescine mainly regulates adipocyte differentiation in the early and intermediate stages. Moreover, we have assessed the expression of polyamine transporter genes in 3T3-L1 preadipocytes and adipocytes. Interestingly, the putrescine-induced adipocyte differentiation was found to be significantly suppressed in response to a treatment with a polyamine transporter inhibitor (AMXT-1501). Furthermore, knockdown experiments using siRNA that specifically targeted SLC3A2 or SLC7A2, revealed that both SLC3A2 and SLC7A2 act as important transporters in the cellular importing of exogenous putrescine. Thus, the exogenous putrescine entering the adipocytes via cellular transporters is involved in adipogenesis through a modulation of both the mitotic clonal expansion and the expression of master transcription factors. Taken together, these results suggest that exogenous polyamines (such as putrescine) entering the adipocytes through polyamine transporters, can stimulate adipogenesis.

A Literatual Study on the Dysphonia (실음(失音)의 병인(病因) 병기(病機)에 대(對)한 문헌적(文獻的) 고찰(考察))

  • Song, Gak-Ho;Roh, Seok-Seon
    • The Journal of Korean Medicine
    • /
    • v.16 no.1 s.29
    • /
    • pp.251-270
    • /
    • 1995
  • In the Literatual Study on the Dysphonia, the results were as follows. 1. The causes of dysphonia are exogenous pathogenic factors,(specially cold evil)internal damage and meridian in The Yellow Emperor's Canon of Interal Medicine, since then endogenous pathogenic factors are lung-asthenia and deficiency of lung-yin etc. The main causes are disease caused by exogenous evils, general body weakness, emotional stimulation and excess of high voice rescently. 2. The pathogenesis of dysphonia originated from two factors; The first internal damages are consumption of body fluid with the formation of dryness evil resulting from the insufficienty of lung-yin and lung-collaterals damaged by heat-evil caused by deficiency of lung and kidney-yin. The second disease caused by exogenous evils is sluggishness of lung-energy caused by exogenous pathogenic factors. 3. The main relative organ are heart, lung and kidney etc. 4. The prescriptions of wind-cold symptoms are Samyoutang(三拗湯) and Hangsosan(杏蘇散), in the prescriptions of phlegm-heat symptom is Chenginyongphetang(淸咽寧肺湯), in the prescriptions of depressive syndrome due to disorder of vital energy are Sogangkitang(小降氣湯) and Shihochenggantang(柴胡淸肝湯加減), in the prescriptions of consumption of body fluid with the formation of dryness evil resulting from the insufficiency of lung-yin symptoms are Sanghangtang(桑杏湯) and Chenginguphetang(淸咽救肺湯, in the prescriptions of deficiency of lung and kidney-yin are Baekhabgokumtang(百合固金湯) and Maekmigiwhangtang(麥味地黃湯). 5. The treatment of acupunctures are used by LI-4(合谷), H-7(湧泉), Liv-3(太衝), K-3(太谿), Sp-6(三陰交), H-5(通里), GV-15(아門), CV-23(廉泉), S-40(農隆), K-6(照海), L-7(列缺), S-36(足三里) etc.

  • PDF

Sales Pattern and Related Product Attributes of T-shirts (티셔츠 상품의 판매패턴과 연관된 상품속성)

  • Chae, Jin Mie;Kim, Eun Hie
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.44 no.6
    • /
    • pp.1053-1069
    • /
    • 2020
  • This study examined the sales pattern relationship with respect to product attributes to propose sales forecasting for fashion products. We analyzed 537 SKU sales data of T-shirts in the domestic sports brand using SAS program. The sales pattern of fashion products fluctuated and were influenced by exogenous factors; therefore, we removed the influence of exogenous factors found to be price discounts and holiday effects as a result of regression analysis. In addition, it was difficult to predict sales using the sales patterns of the same product since fashion products were released as new products every year. Therefore, the forecasting model was proposed using sales patterns of related product attributes when attributes were considered descriptive variables. We classified sales patterns using K-means clustering in order to explain the relationship between sales patterns and product attributes along with creating a decision tree classifier using attributes as input and sales patterns as output. As a result, the sales patterns of T-shirts were clustered into six types that featured the characteristic shape of peak and slope. It was also associated with the combination of product attributes and their values in regards to the proposed sales pattern prediction model.

Effects of Bifidobacterium spp. isolated from the feces of healthy adults on the enhancement of the presentation of exogenous particulate antigen in association of MHC Class I

  • Han, Shin-Ha;Yun, Yun-Ha;Song, Young-Cheon;Park, Eun-Jung;Choi, Sung-Sook;Ha, Nam-Joo;Kim, Kyung-Jae
    • Proceedings of the PSK Conference
    • /
    • 2003.04a
    • /
    • pp.205.1-205.1
    • /
    • 2003
  • Bifidobacterium spp. is nonpathogenic. Gram-positive and anaerobic bacteria, which inhabit the intestinal tract of humans and animals. Bifidobacterium spp. plays important roles in human health. However. the influence of exogenous factors on species composition of fecal bifidobacteria is still unclear. In this study, we wished to determine whether presentation of exogenous OVA (10 $\mu\textrm{g}$/$m\ell$) could be enhanced by the culture supernatant of ten Bifidobacterium spp. (omitted)

  • PDF

Bibliographical study on the Jiu Qi(九氣) shown at Ju Tong Lun(擧痛論) in Shao Wen(素問) Huang Ti Nei Ching(黃帝內經) (${\ll}$소문(素問).거통론(擧痛論)${\gg}$에 나타난 구기(九氣)에 대(對)한 고찰(考察))

  • Kim, Bo-Kyung
    • Journal of Oriental Neuropsychiatry
    • /
    • v.11 no.1
    • /
    • pp.145-167
    • /
    • 2000
  • Jiu Qi(九氣) was shown at Ju Tong Lun(擧痛論) in Shao Wen(素問) Huang Ti Nei Ching(黃帝內經), and is nine important factors that affect the function of human body. Jiu Qi concludes endogenous, exogenous, non-endo-exogenous factors. I do the bibliographical study on the Jiu Qi, the results were as follows; 1. The Qi of Jiu Qi has two opposite meanings. one is genuine vital energy(正氣), and the other is the factors causing abnormal state in vital energy. Jiu Qi is nine factors concluding coldness-heat(exogenous factors). six emotional factors(endogenous factor), overworking(non -endo-exogenous factor). 2. Anger may lead to abnormal rising of vital energy. Anger causes Qi of the liver to go perversely upward, and perverted flow of exuberant Qi of the liver lead to dysfunction of the spleen, so resulted in hematemesis, diarrhea, indigestion. 3. Joy can promote the harmony of vital energy and blood, so do the circulation of nutrient and defensive energy in physiological state. But an excessive joy may lead to the sluggishness of vital energy. 4. The lung keeps the pathway of air unconstructed, disseminates vital energy, cleanses the inspired air and keeps vital energy flowing downward. Sorrow affects on the function of the lung and the heart, so could result in obstruction of the circulation of nutrient and defensive energy. An excessive sorrow after stagnation may lead to the consumption of vital energy. 5. Fear makes vital energy and essence of the kidney sink to inward and downside, makes Yang-Qi can't go upward, so causes obstruction of triple wanner. An excessive fear can obstructs the ascending of Yang-Qi, so may lead to the abnormal falling of vital energy. 6. Coldness makes the sweat pore be contracted, so obstructs the circulation of triple warmer, causes sluggishness of defensive energy or Qi of the internal organ. 7. Heat makes the sweat pore be open, much amount of sweat is excreted with Yang-Qi, defensive energy, vital energy. Heat may consume vital energy. 8. Sudden fright affects on spirits of the heart and liver, causes disorder of the mental faculties and separation of blood and vital energy. Fright may lead to disorder of Qi. 9. Overwork concludes overfatigue and exhaustion caused by intemperance in sexual life. Overwork renders vital energy consumed, and hence results in lassitude and listlessness. 10. Thinking affects on the function of the heart and the spleen. Over thinking may lead to depression of vital energy. Through the bibliographical study on Jiu Qi, I got smallest amount of it, and this must be more investigated correlating with clinical study.

  • PDF

Forecasting Foreign Visitors using SARIMAX Models with the Exogenous Variable of Demand Decrease (수요감소 요인 외생변수를 갖는 SARIMAX 모형을 이용한 관광수요 예측)

  • Lee, Geun-Cheol;Choi, Seong-Hoon
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.43 no.4
    • /
    • pp.59-66
    • /
    • 2020
  • In this study, we consider the problem of forecasting the number of inbound foreigners visiting Korea. Forecasting tourism demand is an essential decision to plan related facilities and staffs, thus many studies have been carried out, mainly focusing on the number of inbound or outbound tourists. In order to forecast tourism demand, we use a seasonal ARIMA (SARIMA) model, as well as a SARIMAX model which additionally comprises an exogenous variable affecting the dependent variable, i.e., tourism demand. For constructing the forecasting model, we use a search procedure that can be used to determine the values of the orders of the SARIMA and SARIMAX. For the exogenous variable, we introduce factors that could cause the tourism demand reduction, such as the 9/11 attack, the SARS and MERS epidemic, and the deployment of THAAD. In this study, we propose a procedure, called Measuring Impact on Demand (MID), where the impact of each factor on tourism demand is measured and the value of the exogenous variable corresponding to the factor is determined based on the measurement. To show the performance of the proposed forecasting method, an empirical analysis was conducted where the monthly number of foreign visitors in 2019 were forecasted. It was shown that the proposed method can find more accurate forecasts than other benchmarks in terms of the mean absolute percentage error (MAPE).