• 운동영양학회지
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• 제25권1호
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• pp.7-15
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• 2021

[Purpose] Sodium bicarbonate shows ergogenic potential in physical exercise and sports activities, although there is no strong evidence which performance markers show the greatest benefit from this supplement. This study evaluated the effects of sodium bicarbonate supplementation on time trial performance and time to exhaustion in athletes and sports practitioners. [Methods] A systematic review was conducted using three databases, including 17 clinical trials. Among these clinical trials, 11 were considered eligible for the meta-analysis according to the criteria for the assessment of methodological quality using the PEDro Scale. Time to exhaustion was assessed in six studies, while time trial performance was evaluated in five studies. [Results] A significant beneficial effect of supplementation on time to exhaustion was found in a random effects model (1.48; 95% confidence interval [CI], 0.49 to 2.48). There was no significant effect of supplementation on time trial performance in a fixed effects model (slope = -0.75; 95% CI, -2.04 to 0.55) relative to a placebo group. [Conclusion] Sodium bicarbonate has the potential to improve sports performance in general, especially in terms of time to exhaustion.

• International Journal of Human Ecology
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• 제6권2호
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• pp.85-94
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• 2005

The purpose of this study is to analyze the preference of spatial elements for common space planning in senior congregate housing. For the study, 500 potential consumer's residing in Seoul was surveyed using the questionnaire in the social survey methodology. As for the common spaces, gardens, treatment, and exercise rooms were preferred. A combination of both separate and group arrangement of the buildings was preferred, indicating that people wanted separation of the common space and the individual living units. Second, people preferred sharing parts of the common space with their neighbors and as is the traditional custom, preferred to take off their shoes at the entrance to individual units. Third, for the furniture and facilities, they wanted the manager room in the lobby, the small meeting rooms in the public dining room, a fitness center in the activity room, the rack or alcove to store items in front of an individuals unit in the hallway, a chair to sit down in the elevator, and the chair to rest on the stairway landing. Fourth, in terms of priority for planning the senior citizens' community housing, safety, familiarity like a regular home, reduced isolation and loneliness, sense of belonging, economic factors, aesthetic appreciation, daily life supplement, variety, and self-identity were answered in that order.

• Journal of Korean Biological Nursing Science
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• 제8권1호
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• pp.23-37
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• 2006

Purpose: This study was performed to identify climacteric symptoms corresponding to the use of complementary and alternative therapy(CAT) in middle aged women. Method: The subjects of the study were 603women(40-64years) and were chosen by convenient sampling from 1 April to 31 July 2004. The collected data was analyzed using descriptive statics, chi-square, t-test analysis by SPSS/WIN program. Results: 1. It was shown that 63.8% of subjects have utilized one or more types of CAT. 2. It was shown that the most frequently used types are health supplement(40.5%), gold acupuncture(31.2%), acupress(24.7%), hand acupuncture(21.8%) 3. There was significant difference in the using experience CAT by religion(p=.029), job(p=.018), hormone replacement(p=.016), exercise(p=.007), health state(p=.013). 4. There was significant difference in climacteric symptoms(p=.000) corresponding to the using experience of CAT. 5. There was significant difference in climacteric symptoms(p=.028) corresponding to the using experience hand therapy of CAT. Conclusion: We found that middle aged women used CAT more than others populations. Future research examining the determinants of CAT use, incorporating attitudinal and health conditions, as well as clinical efficacy, effectiveness, and health outcome studies of specific CAT therapies are warranted.

• 대한지역사회영양학회지
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• 제9권4호
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• pp.511-518
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• 2004

This study was designed to compare general characteristics and dietary habits between volunteers for a nutrition survey and non-volunteers using a questionnaire. Volunteers were recruited by advertising on the homepage of a university to assess nutritional status by examining dietary intake for three days and blood analysis. Non-volunteers were selected from some classes not related to nutrition. There were no significant differences in sex, monthly allowances, eating-out cost, drinking and exercise between the two groups, while the proportion of self-boarding was higher in the volunteer group than in the non-volunteer group, and smoking rate of volunteers was approximately 2.4 times lower than that of non-volunteers. Volunteers were less concerned about their diet than non-volunteers. No significant differences in concern about health, considering factors in their diet, self-evaluation of their diet, learning experience about nutrition, and vitamin/mineral supplement use were observed. The frequency and the place of eating-out for dinner were significantly different between the two groups. More proportions of volunteers tended to eat regularly and eat breakfast. Volunteers consumed seaweeds more frequently, and milk, fruits and fast foods less frequently than non-volunteers. Our results indicate that some characteristics and dietary habits of volunteers are different from those of non-volunteers. However, we could not show that volunteers were more interested in their diet and had desirable dietary habits than non-volunteers. Further research on the characteristics of volunteers who participate in nutrition survey may be helpful to interpret and generalize the survey results.

• 한국의사학회지
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• 제34권1호
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• pp.11-22
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• 2021

In this study, we examine Cho Heon-yeong's medical theory in obstetrics and gynecology by looking at the contents and prescriptions of 『Buinbyeongchiryobeob (婦人病治療法)』. This book is a clinical text on obstetrics and gynecology written in the 1940's. This book consists of an Introduction, Jeungchi (證治), Yangjinhanchi (洋診漢治), Cheobangnonhae (處方論解) and refers to 『Donguibogam(東醫寶鑑)』, 『Keongakjeonseo (景岳全書)』, 『Junguihaksajeon (中醫學辭典)』, 『Jejungsinpyeon (濟衆新編)』, 『Uihakipmun (醫學入門)』 and 『UijongKeumkam (醫宗金鑑)』. Cho Heon-yeong's theory in this book has the following characteristics. First, his medical eclecticism is centered on Korean Medicine, with incidental use of Western medicine. Second, he regarded weakness (虛證) as a vital factor in obstetrics and gynecology. Third, he added "mental state" to the list of basic physiological characteristics of women. Fourth, he presented a new diagnostic standard based on a spectrum of fire (火) and cold (冷). There are 363 prescriptions in this book, and 171 of them are from 『Donguibogam (東醫寶鑑)』. The books frequently used prescriptions are all designed to supplement (補藥). There are 48 prescriptions that original to Cho Heon-yeong. Additionally, this book contains eopsaeng (攝生) and pretended stimulation therapies and exercise methods.

• Nutrition Research and Practice
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• 제5권3호
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• pp.198-204
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• 2011

Target herbal ingredient (THI) is an extract made from two herbs, Scutellariae Radix and Platycodi Radix. It has been developed as a treatment for metabolic diseases such as hyperlipidemia, atherosclerosis, and hypertension. One component of these two herbs has been reported to have anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. However, there have been no reports about the effects of the mixed extract of these two herbs on metabolic diseases. In this study, we investigated the metabolic effects of THI using a diet-induced obesity (DIO) mouse model. High-fat diet (HFD) mice were orally administered daily with 250 mg/kg of THI. After 10 weeks of treatment, the THI-administered HFD mice showed reduction of body weights and epididymal white adipose tissue weights as well as improved glucose tolerance. In addition, the level of total cholesterol in the serum was markedly reduced. To elucidate the molecular mechanism of the metabolic effects of THI in vitro, 3T3-L1 cells were treated with THI, after which the mRNA levels of adipogenic transcription factors, including C/$EBP{\alpha}$ and $PPAR{\gamma}$, were measured. The results show that the expression of these two transcription factors was down regulated by THI in a dose-dependent manner. We also examined the combinatorial effects of THI and swimming exercise on metabolic status. THI administration simultaneously accompanied by swimming exercise had a synergistic effect on serum cholesterol levels. These findings suggest that THI could be developed as a supplement for improving metabolic status.

• 생명과학회지
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• 제17권3호통권83호
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• pp.368-374
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• 2007

본 연구는 장기간의 수영훈련을 마친 통제 훈련군, MCT 투여 훈련군 및 LCT 투여 훈련군에서 지구력 운동수행력과 장기간의 훈련 안정시기 및 운동스트레스 부여시기(실험동물이 상당한 스트레스를 느끼는 160분간의 강제수영)에서 에너지 기질의 변화, 인슐린 호르몬, 및 Lipase 효소의 활성화를 함께 비교하여, 만약 투여 훈련군에서 높은 운동수행력이 나왔다면 이것이 어느 에너지 기질 및 피로물질과 연관되는지 혹은 인슐린 호르몬과 지방분해 효소인 Lipase 효소와는 어떠한 연관이 있는지를 규명하여 지구성 운동수행력에 훈련과 투여효과를 과학적으로 검증하는 데에 연구목적이 있었다. 본 연구에서 사용된 실험동물은 평균체중 140-155 g의 Sprague-Dawley계 횐쥐 수컷으로(7 wk), SPF (Specific Pathogen Free: 특정병원체 부재동물)를 대한바이오링크에서 분양 받은 후에 D대학교 실험동물 사육실에서 사육하였다. 실험동물은 총 54마리를 환경적응과 적응훈련을 포함하는 총 9주간의 훈련을 거친 후 크게 세 그룹으로 나누어 비 투여 그룹 18마리, MCT 투여그룹 18마리, LCT 투여그룹 18마리로 구분하였고 각 그룹에서 안정 시기 6마리와 160분간의 운동 스트레스 시기 6마리 및 지구력 운동수행력시기(survival test) 6마리로 세분화 하여 분석하였다. 본 연구의 결과로 일반적인 지방 형태인 LCT의 투여는 추가적인 체중증가를 일으켰고, 운동수행력의 증가도 가져왔다. 하지만 같은 강도의 운동 부하에 대해서 운동 시 활용되는 지방의 형태인 지방산의 동원이 상대적으로 적었고, 운동증료시기에도 많은 양이 TG의 형태로 존재함을 알 수 있었다. 그리고 운동종료 시 피로물질인 젖산의 축적량이 증가하였고, 지방산화 효소인 Lipase 활성도도 크게 증가하지 않으면서 오히려 인슐린 호르몬을 증가시켜 많은 양의 에너지를 제공하여 지구력 운동 수행에는 도움을 주지만 효율성이 떨어짐을 알 수 있었다. 하지만 MCT의 투여는 인슐린 호르몬의 증가를 일으키지 않으면서 lipase 효소의 활성도를 증가시키고, 젖산 축적을 적게 하면서 유리지방산의 동원을 원활하게 하여 운동 지속시간을 상당히 연장했음을 알 수 있었다. 그리고 TG의 축적을 적게 일으키면서 체중의 감소도 나타났다. 이러한 결과를 통하여 장기간 지구성 운동시 추가적인 에너지 공급을 위해 MCT를 투여하는 것이 운동 수행력의 증가는 물론, 에너지 기질의 활성화를 도모하고 피로물질의 축적을 적게 일으켜, 효율적인 에르고게닉에이드로 권장된다. 뿐만 아니라 에너지 효율성을 증가하여 추가적인 지방축적을 일으키지 않기 때문에, 체중증가를 우려할 필요가 없으며, 오히려 많은 지방을 에너지로 사용하기 때문에 에너지 효율성의 면에서 운동만 한다면 다이어트에도 도움이 되리라 생각한다.

• Biomolecules & Therapeutics
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• 제11권4호
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• pp.257-264
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• 2003

Carnitine, hydroxycitric acid, and soy peptide have been known to be anti-obesity agents. The purpose of this study was to evaluate the combined effects of carnitine, hydroxycitric acid, and soy peptide mixture as a potential anti-obesity supplement in overweight women. Overweight premenopausal women (n=33; PIBW>110; 20 to 39 years) were randomized into two groups: the placebo group and the functional beverage group (the test group). Functional beverage was composed of 2000 mg soy peptide, 20 mg L-carnitine and 300 mg garcinia(40% hydroxycitric acid). Body weight and 3 day food dimes, biochemical measurements and computerized tomography were measured at baseline and 8-week. After 8-week consumption of functional beverage with usual diet and exercise, body weight fell an average of 1.4 kg (2.1%). Visceral fat area reduced an average of 7.8% at L1($69.6{\pm}8.7\;vs\;64.2{\pm}7.5\;\textrm{cm}^2$) and 5.1% ($60.7{\pm}4.9\;vs\;57.6{\pm}4.8\;\textrm{cm}^2$, p<0.05) at L4level after weight loss in the test group. Calf fat area in the test group showed about 10% reduction ($31.0{\pm}2.7\;vs=\;27.7{\pm}1.7\;\textrm{cm}^2$, p<0.05) after weight loss. These reductions in fat areas were not shown in the placebo group. There were tendencies of increase in serum levels of $\beta-hydroxybutyrate$, acetoacetate, and total ketones in the test group. There were 7% and 17% insignificant increase in fasting free fatty acid (FFA) and response area of FFA during oral glucose tolerance test(OGTT), respectively, in this group. ill addition, little weight loss in the test group showed 8% but not significant reduction in insulin response area during OGTT. In conclusion, this study shows that taking a mixture of carnitine, hydroxycitric acid, and soy peptide as a potential anti-obesity supplement for 8-week produced advantageous changes in the weight and visceral fat accumulation of overweight women.

• 한국산학기술학회논문지
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• 제19권5호
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• pp.444-450
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• 2018

본 연구는 유방암 환자의 식행동 수정을 위한 영양중재 효과판정을 위해 전문가 설문을 통한 통계분석으로 진행하였다. 연구의 대상은 2015년 12월부터 2016년 5월까지 강남세브란스병원에서 유방절제수술을 받은 30명의 여성 환자였다. 연구방법은 숙련된 임상영양사가 영양중재 전후 식행동 수정 및 체중 변화를 측정하였고, 운동, 음주 및 건강보조식품 복용여부에 대해서도 조사하였다. 연구결과 본 연구대상자의 평균 연령은 $54.3{\pm}9.3$세이었고, 월평균 체중감소율은 $1.4{\pm}3.5%$이었다. 영양중재 전후 식행동 수정변화 점수는 3점 척도로 측정 시 $2.00{\pm}0.45$ 점에서 $2.76{\pm}0.18$ 점으로 유의하게 상승하는 결과를 보였다(p<0.001). 음주를 하는 환자의 비율은 20%에서 영양중재 후 전원 금주하는 효과를 보였고, 운동수행 비율도 53%에서 영양중재 후 97%로 증가하였다. 건강보조식품의 복용 비율은 40%에서 영양중재 후 20%로 감소하는 결과를 보였다. 이상의 결과를 고려해 볼 때, 유방암환자의 영양중재 후 식행동 수정은 추후 유방암의 재발을 방지하는데 매우 중요하다고 사료된다.

• Journal of Nutrition and Health
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• 제43권3호
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• pp.260-272
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• 2010

This study examined how the participation rates contribute to subjects' outcomes after a nutrition education (once/week) and exercise (3 times/week) intervention program for 12 weeks in 44 obese female subjects. The subjects were divided into two groups: high-participator (HP) or low-participator (LP) groups according to their participation levels based on the median visit value (30 visits out of a total of 48 visits). Daily nutrient intakes assessed by a 24-hour recall, body composition, blood lipid profiles and physical fitness were measured at baseline and after 12 weeks. After the intervention, weight, BMI, percent body fat, and the waist-hip ratio were significantly decreased in the HP group. In addition, the HP group had a greater rates of changes in weight (HP group: -6.6% and LP group: -3.1%, p < 0.01), BMI (-7.0% and -3.2%, p < 0.01), percent body fat (-7.8% and -4.2%, p < 0.05), and waist-hip ratio (-3.1% and -0.4%, p < 0.01) compared to the LP group. Energy-adjusted protein, fiber, potassium, vitamin $B_1$, vitamin $B_6$, and vitamin C were significantly increased in the HP group. The HP group showed a significant increase in HDLcholesterol and a decrease in blood pressure, total cholesterol, LDL-cholesterol, triglycerides, and atherogenic index (AI). While the muscle endurance, muscle strength, power, agility and flexibility were significantly increased in the HP group, agility and balance were improved in the LP group. In addition, dietary behavior score was significantly increased and stress score decreased in the HP group compared to the LP group. High participation rates were correlated with the improvement of the nutrient density (protein, fiber, potassium, Vitamin $B_1$, Vitamin $B_2$, Vitamin $B_6$ and folate), anthropometric parameters (body weight, BMI and percent body fat), serum lipid profiles (HDL-cholesterol, Triglyceride, and AI) and physical fitness (muscle endurance) adjusted for age, menopausal status, alcohol drinking, nutritional supplement use and baseline BMI. Our results suggest that high participation in nutrition education and exercise program was effective not only for weight reduction but also for the improvement of physical fitness in obese women.