• Biomolecules & Therapeutics
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• v.31 no.5
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• pp.573-582
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• 2023

Muscle atrophy is characterized by the loss of muscle function. Many efforts are being made to prevent muscle atrophy, and exercise is an important alternative. Methylglyoxal is a well-known causative agent of metabolic diseases and diabetic complications. This study aimed to evaluate whether methylglyoxal induces muscle atrophy and to evaluate the ameliorative effect of moderate-intensity aerobic exercise in a methylglyoxal-induced muscle atrophy animal model. Each mouse was randomly divided into three groups: control, methylglyoxal-treated, and methylglyoxal-treated within aerobic exercise. In the exercise group, each mouse was trained on a treadmill for 2 weeks. On the last day, all groups were evaluated for several atrophic behaviors and skeletal muscles, including the soleus, plantaris, gastrocnemius, and extensor digitorum longus were analyzed. In the exercise group, muscle mass was restored, causing in attenuation of muscle atrophy. The gastrocnemius and extensor digitorum longus muscles showed improved fiber cross-sectional area and reduced myofibrils. Further, they produced regulated atrophy-related proteins (i.e., muscle atrophy F-box, muscle RING-finger protein-1, and myosin heavy chain), indicating that aerobic exercise stimulated their muscle sensitivity to reverse skeletal muscle atrophy. In conclusion, shortness of the gastrocnemius caused by methylglyoxal may induce the dynamic imbalance of skeletal muscle atrophy, thus methylglyoxal may be a key target for treating skeletal muscle atrophy. To this end, aerobic exercise may be a powerful tool for regulating methylglyoxal-induced skeletal muscle atrophy.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.1
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• pp.159-166
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• 2023

Purpose : The purpose of this study was to compare the differences in muscle activity of the rectus abdominis, internal oblique, and external oblique muscles according to abdominal muscle exercise methods such as plank exercise, side plank exercise, and crunch exercise. Methods : This study was conducted with 37 college students. All subjects participating in this study were randomly assigned to the plank exercise group, the side plank exercise group, and the crunch exercise group. The exercise corresponding to each group was performed for a total of 8 weeks. The muscle activity of the abdominal muscles was measured before the experiment, 4 weeks, and 8 weeks, and the rectus abdominis, internal oblique, and external oblique muscles were measured. Results : As a result of comparison according to the period in the change in muscle activity of the abdominal muscles after exercise, the amount of change in muscle activity in all three muscles showed a significant difference. As a result of the post-hoc analysis, the muscle activity value of the internal oblique muscle after 4 weeks in the plank exercise showed a significant difference from the value after 8 weeks. In the side plank exercise, the muscle activity values of the rectus abdominis and external oblique muscles before and after 4 weeks showed significant differences from those after 8 weeks. And in the crunch exercise, the muscle activity value of the rectus abdominis muscle before exercise showed a significant difference from the value after 8 weeks. Conclusion : Plank exercise increases the muscle activity of the rectus abdominis, side plank exercise increases the rectus abdominis and external oblique muscles, and crunch exercise increases the muscle activity of the rectus abdominis. Therefore, it is thought that the stability of the trunk can be improved more efficiently if all three exercises are performed.

• Korean Journal of Exercise Nutrition
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• v.23 no.1
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• pp.48-54
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• 2019

[Purpose] The combined effect of different types of post-exercise treatment has not been fully explored. We investigated the effect of combined cold water immersion (CWI) and compression garment (CG) use after maximal eccentric exercise on maximal muscle strength, indirect muscle damage markers in the blood, muscle thickness, and muscle soreness score 24 h after exercise. [Methods] Ten men performed two trials (CWI + CG and CON) in random order. In the CWI + CG trial, the subjects performed 15 min of CWI (15℃), followed by wearing of a lower-body CG for 24 h after exercise. In the CON trial, there was no post-exercise treatment. The exercise consisted of 6 × 10 maximal isokinetic (60°·s^-1) eccentric knee extensions using one lower limb. The maximal voluntary contraction (MVC) and maximal isokinetic (60°·s^-1) strength during knee extension, as well as the indirect muscle damage markers, were evaluated before exercise and 24 h after exercise. [Results] The maximal muscle strength decreased in both trials (p < 0.001), with no difference between them. The exercise-induced elevation in the myoglobin concentration tended to be lower in the CWI + CG trial than in the CON trial (p = 0.060). The difference in the MVC, maximal isokinetic strength, muscle thickness, and muscle soreness score between the trials was not significant. [Conclusion] CWI followed by wearing of a CG after maximal eccentric exercise tended to attenuate the exercise-induced elevation of indirect muscle damage markers in the blood.

• Journal of Korean Academy of Nursing
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• v.26 no.3
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• pp.556-575
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• 1996

In an attempt to investigate the effect of a muscle strengthening exercise program on muscle strength, pain, depression, self-efficacy and quality of life of patients with knee osteoarthritis, a pre-experiment, one group pre-test & post-test design, was planned. Muscle strengthening exercise was carried out from May 22 through August 14, 1995 at isokinetic exercise room in rehabilitation department of University Hospital in Taejon. The subjects were seven female clients conveniently sampled from University Hospital located in Taejon, between 39 and 61 years of age, who had a osteoarthritis in knee. Muscle strengthening exercise program was composed of three sessions per week, one isokinetic exercise at angular velocity of 60° and 180° with Cybex isokinetic dynamometer and two resistance home exercise sessions with elastic band. Data were analyzed with frequency, percentage of change, Friedman test, Duncan test using SAS program. Results were obtained as follows : 1) Flexion and extension muscle strength at angular velocity of 60° and 180° were increased after 12weeks' exercise than those of before experiment. But exept flexion muscle strength at angular velocity of 180°(F=3.34, P=0.0261), there was no statistically significant difference among muscle strengths, which is measured every 3 weeks. 2) Pain was decreased after 6weeks' exercise than that of before experiment, and after 12weeks' exercise than that of 6weeks' exercise. There was statistically significant difference (F=4.28, P=0.0396). 3) Depression was increased after 6weeks' exercise than that of before experiment, and after 12weeks' execise than that of 6weeks' exercise. There was no statistically significant difference between before experiment and after 6weeks' exercise. But, there was statistically significant difference between after 6weeks' exercise and 12weeks' exercise(F=9.38, P=0.0035). 4) Self-efficacy was decreased after 6weeks' exercise than that of before exercise. But, it was increased after 12weeks' exercise than that of be-fore exercise and after 6weeks' exercise. But there was no statistically significant difference (F=1.46, P=0.2706). 5) Quality of life was increased after 6weeks' exercise than that of before exercise, and after 6weeks' exercise than that of 12weeks' exercise. But there was no statistically significant differ once (F=1.06, P=0.3816). Thus, the significant of muscle strengthening exercise for the improvement of muscle strength, pain, depression, is verified. But, this study was a pre-experiment with small size subjects. So, con-trolled experimental study is necessary to determine the effect of this muscle strengthening exercise program on muscle strength, pain, depression, self-efficacy, and quality of life of patients with knee osteoarthritis.

• Physical Therapy Korea
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• v.16 no.1
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• pp.18-24
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• 2009

The purpose of this study was to assess the effect of bridging stabilization exercises on trunk muscles activity on and off a Swiss ball. 20 healthy university students volunteered to participate in this study. Subjects were required to complete following four exercises: exercise 1, single bridging exercise; exercise 2, feet on ball bridging exercise; exercise 3, calf on ball bridging exercise; exercise 4, back on ball bridging exercise. Surface electromyography from selected trunk muscles was normalized to maximum voluntary isometric contraction. A repeated measures of ANOVA with post-hoc Bonferroni's correction was used to determine the influence of exercise type on muscle activity for each muscle and descriptive statistics was used to determine local/global muscle ratios. The rectus abdominis of exercise 4 showed significantly higher muscle activity than rectus abdominis of exercise 1, 2, 3 (p<.05). The external oblique of exercise 2, 4 showed significantly higher muscle activity than external oblique of exercise 1 (p<.05). The internal oblique of exercise 2, 4 showed significantly higher muscle activity than internal oblique of exercise 1 (p<.05). The erector spinae of exercise 2, 3, 4 showed significantly higher muscle activity than erector spinae of exercise 1 (p<.05). Median of internal oblique/rectus abdominis ratio of exercise 1 was 1.16, exercise 2 was 2.43, exercise 3 was 2.45, exercise and 4 was 1.27. Median of internal oblique/external oblique ratio of exercise 1 was 1.01, exercise 2 was .91, exercise 3 was .99, and exercise 4 was .93. Muscle activity can be influenced by addition of a Swiss ball in bridging exercises. It is recommend to use a Swiss ball for trunk stabilization exercise.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.1
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• pp.73-81
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• 2021

PURPOSE: This study examined effects of the untact trunk stabilization exercise program on muscle thickness, trunk strength, maximal expiratory flow, and static balance. METHODS: The subjects were 20 normal adults divided into 10 in the contact exercise group and 10 in the untact exercise group. The trunk stabilization exercise program was conducted for four weeks. The muscle thickness was measured using ultrasound. The maximal expiratory flow was measured using Personal Best Full Range Peak Flow Meter. The static balance was measured through Bio-rescue; and the trunk muscle strength was measured by bending the upper body forward and measuring the time for maintaining the posture. RESULTS: Both contact and untact exercise groups showed significant differences in muscle thickness, muscle strength, maximal expiratory flow, and static balance (p < .05). A significant difference in muscle thickness on ultrasound was observed between the contact and untact exercise groups (p < .05). CONCLUSION: Activation of the transverse abdominal muscle requires accurate instructions of the contact exercise, but despite environmental constraints, the untact exercise program is as effective as the contact exercise for improving muscle strength, maximum expiratory flow, and static balance.

• Korean Journal of Applied Biomechanics
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• v.20 no.3
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• pp.285-292
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• 2010

The purpose of this study was to evaluate the influence of respiratory capacity(forced vital capacity), EMG of rectus abdominal muscle, phonation by respiratory muscle strengthening exercise in children with spasticity cerebral palsy. 24 children with spasticity cerebral palsy was randomized in 2 groups, respiratory muscle strengthening exercise and contro group. In the exprimentral groups, respiratory muscle strengthening exercise for 30minutes duration 3 time per week for 8weeks were respectively preformed, Control group was not performed. Before and after experiments, respiratory capacity(forced vital capacity), EMG of rectus abdominal muscle and phonation was measured in all children. In comparison of difference before and after experiment, the respiratory capacity(forced vital capacity) of respiratory muscle strengthening exercise group was significantly increased than the control group(P<.05), rectus abdominal muscle EMG of the respiratory muscle strengthening exercise group was significantly increased more than the control group(P<.05) and MPT of the respiratory muscle strengthening exercise group was significantly increased more than the control group(P<.05). We found that the respiratory muscle strengthening exercise is useful to improve the respiratory capacity and phonation in children with spasticity cerebral palsy.

• The Journal of Korean Physical Therapy
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• v.10 no.1
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• pp.23-30
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• 1998

The purpose of this study was to analyze the delayed muscle soreness after exercise and the indicators of muscle damage. Subjects of this study were 9 male students. Some muscle enzymes and others(GOT, LDH, ALD, CPK in serum, WBC, ESR) that known as the indicators of muscle damage were measured before exercise. After measurements they run on a treadmill ($incline:25\%$, speed;3.5miles/h) for 7 min. on an average. The intensity of this kind of exercise was $90.5\%$ of maximal exercise intensity. After exercise, same indicators were measured at the just after exercise, 24hr after, 48hr after, 72hr after. Also muscle soreness level was evaluated at same intervals by make use of Modified Abraham's scale. The result was as follow: There was no relationships between muscle soreness and the indicators of muscle damage but ALD was the most important indicator that can be explains the muscle soreness very well.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.1
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• pp.41-48
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• 2021

PURPOSE: The purpose of this study was to provide fundamental clinical data to be used in therapeutic approach to patients with patellofemoral pain syndrome by administrating the squat exercise combined with whole body vibration exercise to them and investigating the effect of such exercise to leg muscle activity and muscle fatigue. METHODS: The patients with patellofemoral pain syndrome were randomly assigned to experimental group I (n = 9) where only squat exercise was administered and experimental group II (n = 9) where the squat exercise combined with whole body vibration exercise was provided. The intervention program was administered for two weeks, four days a week, one session a day, three set a session, and 20 reps a set. The pre- and post-test were performed to measure muscle activity and muscle fatigue of vastus medialis and vastus lateralis. RESULTS: The muscle activity significantly changed in both group (p < .05, p < .01, respectively) and the muscle fatigue showed significant change only in group I (p < .05). In addition, there was significant difference between groups in change of muscle fatigue of both muscles (p < .05) but not in change of muscle activity. CONCLUSION: The results showed that both exercise are effective in improving muscle activity, however, that the squat exercise combined with whole body vibration exercise is more effective in preventing muscle fatigue.

• Journal of the Korean Society of Physical Medicine
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• v.6 no.1
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• pp.93-101
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• 2011

Purpose : The purpose of this study was to investigate the effects of maximum muscle activation of lower extremity of facility dwelled elderly Hansen's disease after isometric trunk exercise for 12weeks. Methods:18 elderly Hansen's disease who isometric trunk exercise for 12weeks were recruited for this study. They were instructed to perform maximum muscle activation of lower extremity after exercise. and the subjects were divided into normal sensory group, sensory loss in left foot group, sensory loss in right foot group and sensory loss in both feet group, according to the sensory condition ability on their soles. Results : After exercise, Hamstring muscle increased significantly (p<.05), and activation of the rectus femoris muscle decreased with a significance (p<05). In terms of Post-hoc test for examining the difference in MVIC according to sensory condition, there was significant difference in the normal sensory group, sensory loss in right and left foot group of left hamstring muscle before the exercise(p=.01) and the normal sensory group, sensory loss in both feet group of right hamstring muscle before the exercise(p=.04). Conclusion : These results indicate that the maximum muscle activation was changed after isometric trunk exercise. it could be improved maximum muscle activation of lower extremity muscle after the exercise although there was sensory loss.