• Title/Summary/Keyword: excess lifetime cancer risk

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Methodology on the Safety Goal Setting of Reactor Operation based on the Radiogenic Excess Cancer Risk in Korea (한국인의 초과 방사선 암 위험도 평가에 근거한 국내원전의 안전목표치 설정 방법론)

  • Chang, Si-Young;Chung, Woon-Kwan
    • Journal of Radiation Protection and Research
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    • v.24 no.3
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    • pp.131-142
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    • 1999
  • By using the Korean demographic data and the modified relative risk projection model given in the Committee on the Biological Effect of Ionizing Radiation (BEIR) report-V under the U.S. National Academy of Science, the radiogenic excess risk in Korean population has been evaluated. On the basis of this risk, a safety goal for the safe operation of domestic nuclear power plants has been further derived in terms of personal dose. The baseline risk of death due to all causes in Korea and the trivial risk level, which the society considers safe, were estimated to be $5.2{\times}10^{-3}$ and $5.2{\times}10^{-6}$, respectively. The radiogenic excess cancer risk in Korea has been estimated to be $5.2{\times}10^{-3}$ for tie case of acute exposure to 0.1 Gy and $3.7{\times}10^{-3}$ for the case of chronic lifetime exposure to 1.0 mGy/y. On the basis of these risks estimate, the resulting safety goal for one year opeation of a reactor was 0.05 mSv, which is quite identical with the ALARA guideline prescribed by the USNRC in the Appendix I, 10CFR50.

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Health Risk Assessment of Aldehydes and VOCs in the Activities Space of Young Children -Focused on Child-care Facilities and Indoor Playgrounds- (어린이 주요 활동 공간의 휘발성 유기화합물 노출로 인한 건강 위해성 평가 -보육시설 및 실내놀이터 중심으로-)

  • Yang, Ji-Yeon;Kim, Ho-Hyun;Yang, Su-Hee;Kim, Sun-Duk;Jeon, Jun-Min;Shin, Dong-Chun;Lim, Young-Wook
    • Environmental Analysis Health and Toxicology
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    • v.25 no.1
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    • pp.57-68
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    • 2010
  • This study assessed the lifetime cancer and non-cancer risk of aldehydes and volatile organic compounds exposure of young children at child-care facilities and indoor playgrounds in Korea. The samples were collected at various children's facilities (40 day-care houses, 42 child-care centers, 44 kindergartens, and 42 indoor playgrounds) in summer (Jul~Sep, 2007), winter (Jan~Feb, 2008) and Spring (Mar~Apr, 2008) periods, and analyzed by GC-MS. We estimated the lifetime excess cancer risks (ECRs) of formaldehyde, acetaldehyde, benzene, chloroform, CCI4 and tetrachloroethylene, and the hazard quotients (HQs) of Non-carcinogens (toluene, xylene, benzaldehyde and formaldehyde). Formaldehyde evaluated both cancer and non-cancer risk. The average ECRs of formaldehyde for young children were $1\times10^{-4}{\sim}1\times10^{-5}$ level in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities.

Asbestos Exposure and Risk Assessment by ABS(Activity Based Sampling) for Former Asbestos Mining Areas in Korea (우리나라 일부 석면광산 지역에서 ABS를 이용한 석면노출 및 위해성 평가)

  • Lee, Junhyeok;Kim, Daejong;Choi, Sungwon;Kim, Hyunwook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.25 no.1
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    • pp.72-81
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    • 2015
  • Objectives: The aim of this study was to investigate the exposure and risk assessment of residents near asbestos mines in Korea. Methods: To assess asbestos types and airborne concentrations, air monitoring was performed in the neighborhoods of Kwangcheon (KC) and Sinsuk (SS) mines, which were leading South Korean mines in the past. In addition, activity-based-sampling (ABS) of residents' particular activities were conducted in order to estimate the Excess Lifetime Cancer Risks (ELCRs) for the residents. Conclusions: The average concentration of airborne asbestos in KC was 0.0014 f/cc and 0.0015 f/cc by PCM and TEM, respectively. In SS it was equal at 0.0012 f/cc by PCM and TEM. No statistically significant difference was found in the average concentration of airborne asbestos between the two mines. The average asbestos concentration of ABS was 0.0048 f/cc (PCM) and 0.0042 f/cc (TEM) in KC, while it was 0.0137 f/cc (PCM) and 0.0125 f/cc (TEM) in SS. It was found that the average asbestos concentration of ABS in SS was statistically significantly higher than that of KC (p<0.01). The results of ELCRs by scenario in KC showed that the scenarios of bicycle, car, weed control, weed whacking, child playing in the dirt, and physical training fell within $1{\times}0^{-6}-1{\times}10^{-4}$, which is the acceptable range of ELCR. The scenarios of motorcycle, walker, digging, and field sweeping, however, exceeded the acceptable range. In SS, only the scenario of car fell within the acceptable range, while all of the other scenarios exceeded the acceptable range.

Health Risk Assessment of Occupants in the Small-Scale Public Facilites for Aldehydes and VOCs (일부 미적용 다중이용시설의 실내 공기 중 알데히드류 및 휘발성유기화합물 노출로 인한 건강위해성 평가)

  • Yang, Ji-Yeon; Kim, Ho-Hyun;Shin, Dong-Chun;Kim, Yoon-Shin;Sohn, Jong-Ryeul;Lim, Jun-Hwan;Lim, Young-Wook
    • Journal of Environmental Science International
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    • v.17 no.1
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    • pp.45-56
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    • 2008
  • This study was to assess the lifetime cancer and non-cancer risk of exposure of worker and user at public facilities in Korea to volatile organic compounds (VOCs). We measured the concentrations of two aldehydes and five VOCs in indoor air at 424 public buildings that 8 kinds of public facilities (70 movie theaters, 86 offices, 86 restaurants, 70 academies, 22 auditoriums, 30 PC-rooms, 30 singing-rooms and 30 bars) all over the country. There were estimated the human exposure dose and risks with averages of the using-time and frequency for facility users and office workers, respectively. Carcinogens (formaldehyde, acetaldehyde, and benzene) were estimated the lifetime excess cancer risks (ECRs). non-carcinogens (toluene, ethylbenzene, xylene, and styrene) were estimated the hazard quotients (HQs). The average ECRs of formaldehyde and benzene for facility worker and user were $1{\times}10^{-3}{\sim}1{\times}10^{-4}\;and\;1{\times}10^{-4}{\sim}1{\times}10^{-5}$ level, respectively, in all facilities. HQs of four non-carcinogens did not exceed 1.0 for all subjects in all facilities. The estimated ECRs for restaurant and auditorium were the highest, and the PC-room and bar were the next higher facilities. Furthermore, people in a smoking facility had the highest cancer risk. Higher ECRs of formaldehyde and benzene were observed in indoor smoking facilities such as restaurant and auditorium. Higher HQs of toluene and xylene were observed at the restaurant and office building.

Natural radioactivity level in fly ash samples and radiological hazard at the landfill area of the coal-fired power plant complex, Vietnam

  • Loan, Truong Thi Hong;Ba, Vu Ngoc;Thien, Bui Ngoc
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1431-1438
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    • 2022
  • In this study, natural radioactivity concentrations and dosimetric values of fly ash samples were evaluated for the landfill area of the coal-fired power plant (CFPP) complex at Binh Thuan, Vietnam. The average activity concentrations of 238U, 226Ra, 232Th and 40K were 93, 77, 92 and 938 Bq kg-1, respectively. The average results for radon dose, indoor external, internal, and total effective dose equivalent (TEDE) were 5.27, 1.22, 0.16, and 6.65 mSv y-1, respectively. The average emanation fraction for fly ash were 0.028. The excess lifetime cancer risks (ELCR) were recorded as 20.30×10-3, 4.26×10-3, 0.62×10-3, and 25.61×10-3 for radon, indoor, outdoor exposures, and total ELCR, respectively. The results indicated that the cover of shielding materials above the landfill area significantly decreased the gamma radiation from the ash and slag in the ascending order: Zeolite < PVC < Soil < Concrete. Total dose of all radionuclides in the landfill site reached its peak at 19.8 years. The obtained data are useful for evaluation of radiation safety when fly ash is used for building material as well as the radiation risk and the overload of the landfill area from operation of these plants for population and workers.

Health Risk Assessments using GIS Method for the Abandoned Asbestos Mines (GIS 기법을 이용한 폐석면 광산의 위해성 평가)

  • Choi, Jin-Beom;Son, Ill;Noh, Jin-Hwan
    • Journal of the Mineralogical Society of Korea
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    • v.24 no.1
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    • pp.43-53
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    • 2011
  • Health risk assessments for the abandoned asbestos mine were usually performed with activity-based sampling (ABS) method, which was not a effective tool for indexing health risk on an exact small area of mine. A newly proposed potential index of health risk (PIHR) was applied with proper spatial determination of geographical information system (GIS) to assess quantitatively health risks. A new trial was applied to a certain abandoned mine in Boryong as follows: A high grade area of PIHR was estimated 7.8% of the whole area of the mine (about 27.3 ha). Based on US EPA IRIS (integrated risk information system) model considering lifetime excess cancer risk (LECR), the health risk assessment indicated that the high grade area increased from 3.0 ha through 12.9 ha to 19.5 ha with an increase of asbestos contents in soil from 0.36% (1E-04 level) through 0.1% (3E-05 level) to 0.04% (1E-05 level). These results can be effectively applied to determine reclamation area of the abandoned asbestos mine.

Health Risk Assessment of Lead Exposure through Multi-pathways in Korea (납의 다경로 노출에 의한 건강위해성평가 : 우리 나라 일부 지역 성인들을 대상으로)

  • Chung, Yong;Hwang, Man-Sik;Yang, Ji-Yeon;Jo, Seong-Joon
    • Environmental Analysis Health and Toxicology
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    • v.14 no.4
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    • pp.203-216
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    • 1999
  • This paper describes a set of multi-pathway models for estimating health risk to lead. The models link concentrations of an environmental contaminant (lead) in air, water and food to human exposure through inhalation, ingestion, and dietary routes. Exposure is used as the foundation for predicting risk of health detriment within the population. The process of estimating exposure using often limited data and extrapolating to a large diverse population requires many assumption, inferences, and simplification. This paper is divided into four section. The first section provides lead contaminant levels on obtaining environmental concentration of air, tap water, and foods. The second section provides a discussion of exposure parameters and uncertainty associated predicting human health risk of contaminants. The third and fourth section illustrate lifetime average daily exposure (LADE) and excess cancer risk (ECR) based on exposure parameters. The relationship between concentration of lead in an environmental medium and human exposure is determined with pathway exposure factors (PEFs). The calculation of LADE and ECR is carried out using Monte-Carlo simulation with probability density function of exposure parameters. Examination of the result reveals that, for lead exposure, ingestion (food) is the dominant route of exposure rather than inhalation (air), and ingestion (tap eater).

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Review of the Radiation Risk and Clinical Efficacy Associated with Computed Tomography Cancer Screening (암의 조기발견을 위한 CT촬영에서의 임상적 효능과 방사선위해에 대한 고찰)

  • Kim, Hyun Ja
    • Journal of Radiation Protection and Research
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    • v.38 no.4
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    • pp.214-227
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    • 2013
  • Computed tomographic scan as a screening procedures in asymptomatic individuals has seen a steady increase with the introduction of multiple-raw detector CT scanners. This report provides a brief review of the current controversy surrounding CT cancer screening, with a focus on the radiation induced cancer risks and clinical efficacy. 1. A large study of patients at high risk of lung cancer(the National Lung Screening Trial[NLST]) showed that CT screening reduced cancer deaths by 20%(1.33% in those screened compared with 1.67% in those not screened). The rate of positive screening tests was 24.2% and 96.4% of the positive screening results in the low-dose CT group were false-positive. Radiation induced lung cancer risk was estimated the most important in screening population because ERR of radiation induced lung cancer does not show the decrease with increasing age and synergistic connection between smoking and radiation risk. Therefore, the radiation risk may be on the same order of magnitude as the benefit observed in the NLST. Optimal screening strategy remain uncertain, CT lung cancer screening is not yet ready for implementation. 2. Computed tomographic colonography is as good as colonoscopy for detecting colon cancer and is almost as good as colonoscopy for detecting advanced adenomas, but significantly less sensitive and specific for smaller lesions and disadvantageous for subsequent therapeutic optical colonoscopy if polyps are detected. The average effective dose from CT colonography was estimated 8-10 $mS{\nu}$, which could be a significant dose if administered routinely within the population over many years. CT colonography should a) achieve at least 90% sensitivity and specificity in the size category from 6 and 10 mm, b) offer non-cathartic bowl preparation and c) be optimized and standardized CT parameters if it is to be used for mass screening. 3. There is little evidence that demonstrates, for whole-body scanning, the benefit outweighs the detriment. This test found large portion of patient(86~90.8%) had at least one abnormal finding, whereas only 2% were estimated to have clinically significant disease. Annual scans from ages 45 to 75 years would accrue an estimated lifetime cancer mortality risk of 1.9%. There is no group within the medical community that recommends whole-body CT. No good studies indicate the accuracy of screening CT, at this time. The benefit/risk balance for any of the commonly suggested CT screening techniques has yet to be established. These areas need further research. Therefore wild screening should be avoided.

Asbestos Exposure and Health Risk Assessment for the Residents Near the Abandoned Mining Area in Chungbuk, Korea (충북지역 폐석면광산 인근주민의 석면노출과 건강위해도 평가)

  • Shin, Jin-Ho;Oh, Seok-Ryul;Hwang, Soon-Yong;Chung, Sook-Nye;Kim, Ji-Hui;Nam, Eun-Jung;Lee, Jin-Hyo;Choi, Hee-Jin;Eom, Seok-Won;Chae, Young-Zoo;Park, Chul-Hwi
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.5
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    • pp.345-350
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    • 2012
  • To investigate the exposure and health risk assessment for the residents near the D-asbestos mine in Chungbuk, Korea. We analyzed asbestos in the 20 ambient air and 23 activity based samples near the mine. The airborne sample results are showed that 8 of 20 samples ranged between 0.0025 to 0.0029 f/cc (fiber per cubic centimeter) and the others were below the detection limit by phase contrast microscopy (PCM). In addition, asbestos fibers were under the detection limit or not being by transmission electron microscopy (TEM). Based on interview and survey targeting the local residents, we made the activity based sampling (ABS) scenarios fit to the conditions of field. At the same time, we calculated the excess lifetime cancer risk (ELCR) of these ABS scenarios according to the ELCR average value and 95% upper confidence limit (UCL). At the case of weed whacking, soil digging and sweeping yard scenario, 95% UCL of ELCR exceeded the $1{\times}10^{-4}$, acceptable risk range for exposure. Based on our study results, it is necessary safety measures such as risk communication, abatement or management of naturally occurring asbestos (NOA).

A study of asbestos risk at some naturally occurring asbestos areas, Korea (우리나라 일부 자연발생석면 발생가능지역의 석면 위해도에 관한 연구)

  • Jung, Joon Sig;Shim, In Keun;Jung, Hyen Sung;Lee, Kyu Mok;Kim, Seong Mi;Kwon, Myung Hee;Chung, Hyen Mi
    • Journal of odor and indoor environment
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    • v.17 no.4
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    • pp.330-336
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    • 2018
  • The objective of this study was to determine whether crops and fruits absorb the naturally occurring asbestos (NOA). The concentration of asbestos in various crops and fruits grown in NOA areas was analyzed and background levels of asbestos in ambient air and soil samples were assessed. Actinolite/Tremolite asbestos were detected in all soil samples. Among 21 ambient air samples, 2 samples were recorded to contain 0.0005 f/cc (fiber per cubic centimeter) but no asbestos was detected in the other samples using transmission electron microscopy (TEM). However, no evidence suggesting that the crops and fruits could be contaminated by NOA was found in this study. The excess lifetime cancer risks (ELCRs) of ABS scenarios (agricultural activities) used in this study were calculated by using the Arithmetic (AM) and Geometric mean (GM) of ELCRs. The AM and GM of ELCRs estimated from digging soil and weeding activities did not exceed $1{\times}10^{-4}$, which was defined as the general acceptable risk range for exposure. The results of this study would be informative to NOA managers and related policy makers to make plans to prevent unexpected exposure to asbestos to residents living in an NOA area.