• 한국임상약학회지
• /
• 제30권3호
• /
• pp.196-205
• /
• 2020

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both first- and second-line therapy in postmenopausal women with osteoporosis and osteopenia with risk factors by using the Fracture Risk Assessment Tool (FRAX). Methods: We conducted a medication use evaluation of denosumab in 98 patients who had been treated three or more times for osteoporosis or osteopenia at Chungnam National University Hospital from July 1^st, 2017 to January 31^st, 2020. Risk factors were identified using quantitative N-gram analyses of FRAX estimations. Patient information, including menopause status and results of bone mineral density tests (T-score), was obtained from electronic medical records. Results: Age, body mass index (BMI), prior medication use, and T-score were identified as risk factors and were included as variables in the evaluation of denosumab use. Since no significant differences were detected between groups, denosumab is likely effective regardless of age or BMI. In addition, no significant difference was detected in T-scores following denosumab treatment, between groups who took bisphosphonates and selective estrogen receptor modulators (SERMs) with denosumab as first-line therapy for postmenopausal osteoporosis. Denosumab may, therefore, be effective as second-line therapy. Conclusion: Efficacy of denosumab was evaluated in postmenopausal women with osteoporosis. Denosumab may be used as first- and second-line therapy regardless of age, BMI, and prior use of bisphosphonates and SERMs.

• 한국의류학회지
• /
• 제23권8호
• /
• pp.1194-1205
• /
• 1999

The hand characteristics of bast blended fabrics are studied by a subective evaluation method. To offer basic data for development of better hand of bast fiber fabrics customer's hand preference surveys are executed as well. IN this study 51 varieties of linen or ramie blended fabrics of various blending ratio density and thickness and Hansan ramie Chinese ramie and a Shingosen fabics of various blending ratio density and thickness and Hansan ramie Chinese ramie and a Shingosen farbic and used. To evaluate the hand of the fabrics subjectively nine ranks' semantic differential scale questions of 26 items are developed with adjective pairs. A seven ranks' scale is also developed to evaluate hand preferences in blouse and jacket cloths, Through subjective evaluation of bast blended fabrics the 26 items could be classified into seven kinds of hand classification : surface characteristics extensibility/drapability felling of heaviness stiffness resilience moisture property and feeling of density. The cumulative variance value explained by these seven factors is 67.18% According to the results of fabrics' preference by age groups no significant differences are found in blouse cloths but a few significant differences are found among different age groups in jacket clothes. However experts and non-experts show considerable differences on preference It can be concluded that fabrics' preference I more dependent on professionality than on age. In the survey experts. However more drapery cloths are preferred by experts and cloths with drier touch are preferred by non-experts. Experts prefer rougher less even less winding heavier and sparser fabrics but non-experts prefer rougher lighter thinner and stiffer fabrics as jacket cloths.

• 한국의류학회지
• /
• 제18권3호
• /
• pp.311-326
• /
• 1994

The purpose of this study was to identify 1) the effect of two contexts (job interview, Informal outing) and clothing cues (type, style, color) on male impresssions 2) the effect of perceiver's age on male impressions created by the clothing cues and contexts. The subjects consisted of 256 male undergraduate students and 256 middle-aged men. The experimental materials developed for this study were a set of stimuli and response scales. The stimuli were 8 color photographs of drawings of a male figure in clothing which were manipulated in two levels, each of three clothing cues including type, style and color. The experimental design was full factorial design of $(2^4contex^2{\times}clothing type^2{times}clthing color^2$. Each of the 16 sub-samples includes 16 subjects from the two perceiver group. Questionnaires used to measure perceivers responses to the stimuli were 7-point semantic differential scales composed of 37 bipolar adjectives representing personal traits. The data was processed by factor analysis, ANOVA, multiple classification analysis, Duncan's multiple range test. The major findings drawn from this study were as follows: 1. Three factors emerged to account for the dimensional structure of the impressions of the male figure in clothing in two social situations. These factors involved evaluation, activity and uniqueness. 2. The contexts, clothing types and clothing styles had significant effects on evaluation, activity and uniqueness. The clothing styles had a considerable effect on both evaluation and uniqueness while the clothing types affected activity. The clothing color had least effect on the impression and had only moderate effect on evaluation. 3. Perceiver's age influenced impressions formed by the social contexts and clothing cues. Male college students were least affected by contexts and clothing cues, while middle-aged men wert affected most.

• 한국가금학회지
• /
• 제45권1호
• /
• pp.63-71
• /
• 2018

본 실험은 산란계의 주령이 계란의 품질에 미치는 효과를 조사하고자 국내 집하장 15개소에서 주령별 원료란 50개를 5주간 채취하여 난중과 계란 내 외부 품질을 평가하였다. 총 8,300개의 계란을 집하장에서 세척 등 등급판정 생산 공정전 무작위로 채취하였다. 산란계의 주령은 20~65주령으로 5단계의 주령으로 구분하여 분석하였다. 주령이 증가할수록 난중은 증가하였으며, 호우유닛은 감소하였다. 난황색은 25~35주령에서 가장 높게 조사되었다. 오염란의 발생비율은 18~25주령에서 가장 높았으며, 26주령 이상에서는 차이가 발견되지 않았다. 계란의 외관평가에서 점란과 사포란의 발생비율은 주령이 증가할수록 증가하였지만, 칼슘스프레싱과 misshapen egg는 18~25주령에 가장 높게 조사되었다. 파각 발생율은 주령과 함께 증가하였으며, 파각의 유형에서는 별과 머리카락 모양이 높은 수준으로 발견되었다. 구멍 모양은 전 구간에 걸쳐 1% 미만으로 조사되었다. 혈반은 전 구간에 낮게 발견되었지만, 56~65주령에서 가장 높았다. 육반은 혈반과 비교하여 높은 수준으로 발생하였으며, 56~65주령에서는 10%이상 발견되었다. 본 연구에서는 청결상태를 나타내는 오염란의 비율이 높은 수준으로 조사되어 세척 공정이 필요할 것으로 조사되었다. 또한 주령이 증가할수록 파각이 많이 발생하고, 육반이 상대적으로 높은 수준으로 조사되었다. 본 연구를 바탕으로 계란의 내 외부 품질을 향상 시킬 수 있는 전략과 더불어 육안으로 확인이 불가능한 파각란에 대한 관리 대책이 필요하겠다.

• International Journal of Computer Science & Network Security
• /
• 제22권12호
• /
• pp.239-244
• /
• 2022

The study aimed to build a program in activities for early childhood students to develop some of the basic skills necessary for the age of artificial intelligence, to achieve the objectives of the study , the researcher used the experimental design, and the research sample consisted of 37 early childhood students. The study used the following tools: Experimental treatment subject: the proposed program in the activities, Measurement and evaluation tool: testing the basic skills needed for the age of artificial intelligence. The study concluded several results: There is a statistically significant difference (α≤0.05) between the average grades of the early childhood students in the research group in the tribal and remote measurements to test the basic skills necessary for the age of artificial intelligence in favor of the students grades in the dimensional measurements. Practical application of the study through benefiting from the proposed program of activities prepared in the current study in planning and implementing activities to develop the basic skills necessary for the age of artificial intelligence among early childhood students.

• 대한가정학회지
• /
• 제29권2호
• /
• pp.241-248
• /
• 1991

The aim of this study is to propose the criteria for a evaluation model of the lifetime household work and organize the model. The results were as follows: Three criteria for a evaluation model of the life-time household work were proposed. $\circled1$ An appropriate framework of the evaluation model should be based on the transition of the family life. $\circled2$ The model should include major variables influencing the value of household work of homemaker. $\circled3$ The model should be flexible enough to accommodate various evaluation methods, and should reflect idiosyncracies of different evaluation methods. In view of the criteria stated above, the present study is based on the family life cycle framework. And the age of the last offspring exhibits a consistent major influence in the evaluation based on the household work hours, while the education level of homemakers shows a consistent major influence in the evaluation based on household worker. So as to reflect these two major variables in the family life cycle framework.

• 대한음성학회:학술대회논문집
• /
• 대한음성학회 2005년도 추계 학술대회 발표논문집
• /
• pp.141-144
• /
• 2005

The purpose of this study is to identify the acoustic changes according to age and to provide the evaluation criteria of elderly voice. The number of 120 Korean adults (three age groups * two sex groups) proceeded sustained three vowels, read apart of 'Taking a walk' and explained a picture. The data was analyzed acoustically with MDVP of CSL. The results showed that: 1)there was statistically most significant changes in sex and age in F0 than the others but no significant in Shimmer. 2)acoustic parameters were changed from young adulthood to old age. Different patterns of change with aging were observed in men and women.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 1996년도 가을 학술발표회 논문집
• /
• pp.352-357
• /
• 1996

In hardening massive concrete, the heat of hydation gives rise to considerable thermal gradientsand thermal stresses, which might cause early age cracking. This paper deals with the results of evaluation of hydration heat of low hear concrete, using Belite rich cement (low heat cement) and compared with OPC, slag added cement and fly ash addedcement. Result of evaluation of hydration are presented in this paper. The concrete made with Belite rich cement gets low temperature of center point and low thermal gradients between surface and center points.

• 농촌의학ㆍ지역보건
• /
• 제22권2호
• /
• pp.195-213
• /
• 1997

This study was carried out to investigate several effects of smoking and alcohol-drinking on the health of rural residents. The subjects were 710 people (325 males and 385 females) in rural area, Young-Duk Gun, Kyungbuk, Korea. The data were collected by medical students trained for this study during 4 days from 31 August, 1996. Questionnaire contents were general social characteristics, period of the agriculture, smoking history, alcohol-drinking history, some psychosomatic symptoms and self-evaluation for health. The results obtained are as follows : 1. Positive rates of the some psychosomatic symptoms and self-evaluation for health were higher in female than in male and were significantly increased as the as increased(p<0.05). 2. Smoking rate was 56.9% in male and 4.9% in female. In positive rates of the some psychosomatic symptoms and self-evaluation for health in male, 'insomnia' was only significantly lower in ex-smoker than in smoker and non-smoker(p<0.05). Other items were significantly not different. 3. Prevalence rate of alcohol drinker was 54.8% in male and 17.1% in female and the alcoholism was 8.3% in male and 0.8% in female. Positive rate of the some psychosomatic symptoms and self-evaluation for health in male were significantly not different. 4. The scores of self-evaluation for health was divided into two groups under two point and over three. And the analysis of multiple logistic regression shows that there were significant relationship with age and sex. This study suggests that some psychosomatic symptoms and self-evaluation for health were significant relationship with age and sex but not smoking and alcohol-drinking.

• Imaging Science in Dentistry
• /
• 제44권3호
• /
• pp.185-191
• /
• 2014

Purpose: This study investigated the developmental stages of third molars in relation to chronological age and compared third molar development according to location and gender. Materials and Methods: A retrospective analysis of panoramic radiographs of 2490 patients aged between 6 and 24 years was conducted, and the developmental stages of the third molars were evaluated using the modified Demirjian's classification. The mean age, standard deviation, minimal and maximal age, and percentile distributions were recorded for each stage of development. A Mann-Whitney U test was performed to test the developmental differences in the third molars between the maxillary and mandibular arches and between genders. A linear regression analysis was used for assessing the correlation between the third molar development and chronological age. Results: The developmental stages of the third molars were more advanced in the maxillary arch than the mandibular arch. Males reached the developmental stages earlier than females. The average age of the initial mineralization of the third molars was 8.57 years, and the average age at apex closure was 21.96 years. The mean age of crown completion was 14.52 and 15.04 years for the maxillary and the mandibular third molars, respectively. Conclusion: The developmental stages of the third molars clearly showed a strong correlation with age. The third molars developed earlier in the upper arch than the lower arch; further, they developed earlier in males than in females.