• 제목/요약/키워드: evaluation materials

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EFFICACY EVALUATION OF THE WHITENING COSMETICS USING MELANOGENESIS INHIBITION ASSAY COSMETICS IN B-16 MELANOMA CELL

  • S. J. Yang;S. J. Jang;Park, S. S.;J. Y. Jang;K. H. Son;Lee, J. P.;Lee, K. S.;M. Y. Heo;Kim, Y. O.
    • 대한화장품학회:학술대회논문집
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    • 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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    • pp.544-544
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    • 2003
  • We investigated the inhibitory effect of whitening materials with growth factor or alone on melanomas derived from Human (B-16) and mouse (SK-MEL-31) using melanin content. Melanin content was determined by the absorbance value at 470nm per cells. we used the growth factors known as activators of Adenylate cyclase, Protein kinase C and tyrosine kinase pathway separately. In addition, we compared the action of UV-induced with non-biological growth factor with whitening materials in melanomas derived from Human and mouse. The results showed that the aspect of inhibitory effect of whitening materials on B16 and SK-MEL-31 was not different. And, the action of each growth factor involved in the differentiation and proliferation of melanoma on the inhibition of melanogenesis in B-16 and SK-MEL-31 using whitening agents showed no difference. Also, The action of UV -induced and non-biological growth factors didn't exhibit different pattern on the effect of whitening agent in B-16 and SK-MEL-31.

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EFFICACY EVALUATION OF THE WHITENING COSMETICS USING IN VITRO TYROSINASE INHIBITION ASSAY

  • Lee, J. P.;Kim, Y. O.;J. Y. Jang;K. H. Son;S. J. Yang;Lee, K. S.;Kim, W. H.;J. T. Hong;Park, S. S.
    • 대한화장품학회:학술대회논문집
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    • 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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    • pp.479-479
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    • 2003
  • We investigated the tyrosinase inhibitory effect using whitening materials such as arbutin, ethyl ascorbyl ether, glabridin, kojic acid, magnesium ascorbyl phosphate and ascorbic acid. Tyrosinase inhibition rate were determined varying the enzyme concentration, reaction time, reaction temperature and pH. The optimal conditions to measure the inhibitory efficacy were as follows. : enzyme concentration 1,500 or 2,000IU/mL, reaction time 15min(for the enzyme concentration 1,500 IU/mL) and l0min(for the enzyme concentration 2,000IU/mL), reation temperature 42$^{\circ}C$, pH 6.5. Under these conditions $IC_{50}$/ of arbutin, ethyl ascorbyl ether, glabridin, kojic acid, magnesium ascorbyl phosphate and ascorbic acid were calculated. In the case of magnesium ascorbyl phosphate, the inhibitory effect of tyrosinase was very low and the $IC_{50}$/ of magnesium ascorbyl phosphate could not be calculated. Other five materials showed good inhibitory effect of tyrosinase and can be used for the whitening materials.

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Criteria for clinical translucency evaluation of direct esthetic restorative materials

  • Lee, Yong-Keun
    • Restorative Dentistry and Endodontics
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    • 제41권3호
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    • pp.159-166
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    • 2016
  • The purpose of this review was to suggest practical criteria for the clinical translucency evaluation of direct esthetic restorative materials, and to review the translucency with these criteria. For the evaluation of reported translucency values, measuring instrument and method, specimen thickness, background color, and illumination should be scrutinized. Translucency parameter (TP) of 15 to 19 could be regarded as the translucency of 1 mm thick human enamel. Visual perceptibility threshold for translucency difference in contrast ratio (${\Delta}CR$) of 0.07 could be transformed into ${\Delta}TP$ value of 2. Translucency differences between direct and indirect resin composites were perceivable (${\Delta}TP>2$). Universal and corresponding flowable resin composites did not show perceivable translucency differences in most products. Translucency differed significantly by the product within each shade group, and by the shade group within each product. Translucency of human enamel and perceptibility threshold for translucency difference may be used as criteria for the clinical evaluation of translucency of esthetic restorative materials.

영어 교재 분석 평가의 사례 (A case study of ELT textbook analysis)

  • 김정민;김해동;박종헌;유재신;이길영;이충현;장수현
    • 영어어문교육
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    • 제13권4호
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    • pp.233-252
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    • 2007
  • The aim of this study is to propose a systematic way of evaluating competing ELT textbook series. Three stages of evaluation procedures were employed: A sample of two sets of English textbook series for young learners were first analysed by five trained textbook evaluators using a checklist. Second, based on the results of analysis, evaluative discussion was carried out. Third, two independent evaluators conducted impressionistic evaluation on the series. The procedure employed in this materials evaluation process can be adapted in choosing series of textbooks. Since not many studies have dealt the evaluation of textbook series by multiple evaluators, the method presented in this study can be referred to and applied by materials evaluators in other contexts.

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화학 분석 결과의 QA/QC를 위한 측정 불확도 (Measurement uncertainty for QC/QA applied to the chemical analysis)

  • 우진춘;오상협;김병문;배현길;김광섭;김용두
    • 분석과학
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    • 제18권6호
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    • pp.475-482
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    • 2005
  • 화학분석 분야에는 ISO 17025에 따른 체계적 품질 관리/보증의 요구가 커지면서, 측정 불확도의 표기가 크게 요구되고 있다. 측정품질의 정량화를 위하여, 화학분석의 QA/QC 문헌들로부터 화학분석 품질에 영향을 미치는 중요한 불확도 요소를 선정하였고, 이것을 측정결과 평가 요소의 기본인 7개의 품질요소로서 반복성, 직선성, 소급성, 변동성, 매질효과, 균질성, 안정성으로 구분하였다. 화학분석의 QA/QC를 위한 이 7대 품질 요소의 측정 모델화, 표준불확도의 계산 및 합성방법을 각각 예로서 제시하였다.

Evaluation of cryogenic mechanical properties of aluminum alloy using small punch test

  • Hojun Cha;Seungmin Jeon;Donghyeon Yoon;Jisung Yoo;Seunggun Lee;Seokho Kim
    • 한국초전도ㆍ저온공학회논문지
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    • 제25권4호
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    • pp.70-74
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    • 2023
  • The Small Punch Test (SPT) was developed to evaluate the softening and embrittlement of materials such as power plants and nuclear fusion reactors by taking samples in the field. Specimens used in the SPT are very thin and small disk-shaped compared to specimens for general tensile test, and thus have economic advantages in terms of miniaturization and repeatability of the test. The cryogenic SPT can also be miniaturized and has a significantly lower heat capacity than conventional universal test machines. This leads to reduced cooling and warm-up times. In this study, the cryogenic SPT was developed by modifying the existing room temperature SPT to be cooled by liquid nitrogen using a super bellows and a thermal insulation structure. Since the cryogenic SPT was first developed, basic experiments were conducted to verify the effectiveness of it. For the validation, aluminum alloy 6061- T6 specimens were tested for mechanical properties at room and cryogenic temperature. The results of the corrected tensile properties from the SPT experiment results were compared with known room temperature and cryogenic properties. Based on the correction results, the effectiveness of the cryogenic SPT test was confirmed, and the surface fracture characteristics of the material were analyzed using a 3d image scanner. In the future, we plan to conduct property evaluation according to the development of various alloy materials.

원전 재료열화 평가프로그램 개발 (Development of Materials Degradation Evaluation Program for Nuclear Power Plants)

  • 신호상;오영진
    • 한국압력기기공학회 논문집
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    • 제7권3호
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    • pp.23-29
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    • 2011
  • The renewed global interest in nuclear power has arisen from the need to reduce greenhouse gas emissions and to provide sufficient electricity for a growing global population before the accident at Fukushima Dai-ichi nuclear power plant in Japan. In spite of the safety issues of nuclear power plants raised by the ongoing Japanese nuclear crisis, many countries with nuclear power plants (NPPs) are still implementing license extensions of 10~20 years, and even consideration is being given to the concept of life-beyond-60, a further period of license extension from 60 to 80 years. To solving the materials aging problem is integral to its success. To evaluate the plant aging phenomena, a lot of background information such as materials and environment of the parts of the reactor and plant systems is needed by the experts. Information on degradation mechanisms is also used. In this paper, a materials degradation evaluation program called OnMDE-SYS (On-line Materials Degradation Evaluation System) is introduced. The developed program provides a variety of information on the materials and stressors as well as operational experience to the experts. It is also anticipated that the experts can perform materials degradation assessment on the web directly by referring to domestic and international information about the degradation of a nuclear power plants through OnMDE-SYS.

대기 중의 ppb 농도의 VOC의 분석을 위한 저온농축장치의 제작과 성능평가 (Construction and Evaluation of Cryogenic Preconcentration System for Analysis of VOC with ppb Level in the Air)

  • 전선주;허귀석;김병주;김진석
    • 분석과학
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    • 제12권4호
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    • pp.332-340
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    • 1999
  • 본 연구에서는 canister에 채집한 대기시료 중의 VOC 성분을 농축하기 위해 home-made 저온농축장치를 제작하였다. 제작한 저온농축장치와 GC-MS 분석장치를 이용하여 대기 시료 중에 ppb 농도로 존재하는 EPA의 TO-14 법에서 규정한 성분들을 정량하였다. 제작한 homemade 농축장치에 의한 분석의 결과를 종전에 사용해 오던 흡착관법의 결과와 비교함으로써 제작한 system의 성능을 평가하였고 그 결과 benzene, toluene, ethylbenzene 및 xylene류의 농도가 잘 일치하였다.

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Composite insulator의 특성평가 방향 및 필요성 (Evaluating methods of properties in composite insulators and necessities)

  • 김인성;조한구;강동필
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 하계학술대회 논문집 C
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    • pp.1226-1228
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    • 1995
  • This paper introduced foreign standard testing methods on composite insulators(for transmission, distribution) and mentioned on (1)evaluation of material property (2)short-term test of prototype (3)insulation efficiency on use to evaluation property of insulators made of composite insulating materials.

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