• Journal of Community Nutrition
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• 제8권2호
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• pp.90-95
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• 2006

Asian Americans is a minority population contributing approximately 4% to the total population of the United States, however it is one of the fastest growing populations. Although Asian Americans as a group have socioeconomic profiles that are similar to white Americans, significant variations exists within and across Asian ethnic groups. The top ten leading causes of death for Asian Americans includes cancer, heart diseases, stroke, unintentional injuries, diabetes, influenza and pneumonia, chronic lower respiratory disease, suicide, nephritis, and septicemia. The prevalence of obesity is lower among Asian Americans, however this should be taken with considerations specific to Asians. High salt and low calcium consumption seem to be dietary risk factors for Asian Americans, although dietary patterns are changing with acculturation. Factors affecting dietary patterns are discussed in this paper. A proactive nutrition education approach for Asian Americans should be promoting maintaining 'healthy' aspects of ethnic diets and adopting 'healthy' American diets. Collaboration with nutrition educators in Asian countries would be helpful to overcome limited resources available for researching and developing nutrition education messages and materials for Asian Americans. (J Community Nutrition 8(2): 90-95, 2006)

• 한국식생활문화학회지
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• 제16권5호
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• pp.492-503
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• 2001

The purpose of this study was to compare nutritional intakes of college students in Seoul and Yanbian by ethnic : Korean, Korean-Chinese, Chinese. The questionnaire were applied to individual interviewing method. Statisticai data analysis was completed by SAS 8.0 package program for t-test, ANOVA and multiple comparison. The results of this study were as follows. Average energy intake per day was high in Korean-Chinese. Nutrient Adequacy Ratio(NAR) was highest in iron and lowest in zinc. Mean Adequacy Ratio(MAR) score was $0.68{\sim}0.85$ for each group. The indexes of nutritional quality(INQ) were over 1.0 for most nutrients except 0.41 of zinc and 0.76 of calcium. Average energy intake ranked high in Korean-Chinese, Korean and Chinese.

• Animal cells and systems
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• 제7권2호
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• pp.145-149
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• 2003

Adult periodontitis is a chronic inflammatory disease whose etiology is not well defined. Recent studies have shown that vitamin D receptor gene has been a candidate for the susceptibility of adult periodontitis. The purpose of this study is to investigate the frequency of Taq I restriction fragment length polymorphism (RFLP) in the vitamin D receptor gene in nan periodontically healthy controls and 28 adult periodontitis patients. Taq I RFLP in the vitamin D receptor gene was detected by PCR amplification, followed by restriction enzyme digestion and 2％ agarose gel electrophoresis. There was no significant difference in the distribution of Taq I RFLP between healthy controls and adult periodontitis group (P > 0.05). Thus, Taq I RFLP in the vitamin D receptor gene may not confer the susceptibility to adult periodontitis in Korean population. However, t allele distributions of this RFLP showed various frequencies among ethnic groups studied. Further studies in other ethnic groups will be required.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6391-6395
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• 2012

Background: Ovarian cancer is ranked as the fifth most common cause of cancer death in women. In Malaysia, it is the fourth most common cancer in females. CA125 has been the tumor marker of choice in ovarian cancer but its diagnostic specificity in early stages is only 50%. Hence, there is a critical need to identify an alternative tumor marker that is capable of detecting detect ovarian cancer at an early stage. HE4 is a new tumor marker proposed for the early diagnosis of ovarian cancer and disease recurrence. Currently, none of the normal ranges of HE4 quoted in the literature are based on data for a multiethnic Asian population. Therefore, the aim of this study was to determine reference intervals for HE4 in an Asian population presenting in University Malaya Medical Centre, a tertiary reference hospital. Materials and Methods: 300 healthy women were recruited comprising 150 premenopausal and 150 postmenopausal women, aged from 20-76 years. All women were subjected to a pelvic ultrasonograph and were confirmed to be free from ovarian pathology on recruitment. Serum HE4 levels were determined by chemiluminescent microparticle immunoassay (CMIA, Abbott Architect). The reference intervals were determined following CLSI guidelines (C28-A2) using a non-parametric method. Results: The upper limits of the $95^{th}$ percentile reference interval (90%CI) for all the women collectively were 64.6 pmol/L, and 58.4 pmol/L for premenopausal) and 69.0 pmol/L for postmenopausal. The concentration of HE4 was noted to increase with age especially in women who were more than 50 years old. We also noted that our proposed reference limit was lower compared to the level given by manufacturer Abbott Architect HE4 kit insert (58.4 vs 70 pmol/L for premenopausal group and 69.0 vs 140 pmol/L in the postmenopausal group). The study also showed a significant difference in HE4 concentrations between ethnic groups (Malays and Indians). The levels of HE4 in Indians appeared higher than in Malays (p<0.05), while no significant differences were noted between the Malays and Chinese ethnic groups. Conclusions: More data are needed to establish a reference interval that will better represent the multiethnic Malaysian population. Probably a larger sampling size of equal representation of the Malay, Chinese, Indians as well as the other native ethnic communities will give us a greater confidence on whether genetics plays a role in reference interval determination.

• 한국지역지리학회지
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• 제12권2호
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• pp.265-280
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• 2006

본 연구 목적은 한국과 일본의 문화적 특성이 자국민의 해외여행 행태 및 여행사의 기업전략에 끼친 영향을 밝히는데 있다. 이와 관련하여 본 연구에서는 한국과 일본 관광객의 해외여행 행태, 여행의 진행과정, 여행업의 구조변화, 관광분야 해외직접투자 등에 대해 조사하였다. 한국과 일본의 국제관광에 있어서 뚜렷이 구분되는 특징은 높은 패키지여행 비중, 강한 민족적 연계, 대형 도매여행사 중심의 여행업 구조개편, 해외 현지지사의 설립과 리조트 및 호텔에 대한 해외직접투자 둥으로 요약된다. 호주여행에 있어서 한국과 일본의 이러한 두드러진 특징은 강한 집단의식과 언어 및 음식과 같은 문화적 특성에 의해 영향 받은 것으로 판단된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권5호
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• pp.364-371
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• 2002

Many chemical compopunds are converted into reactive electrophilic metabolites by the oxidative(Phase I) enzymes, which are mainly cytochrome P-450 enzyme(CYPs). Phase II conjugating enzymes, such as glutathione S-transferase(GST), usually act as inactivation of enzymes. Genetic polymorphisms have been found to be associated with increased susceptibility to cancer of the lung, bladder, breast and colorectal. Many of the polymorphic genes of carcinogen metabolism show considerably different type of cancer among different ethnic groups as well as individuals within the same group. The aim of this study is (1) to establish the frequencies of genetic polymorphisms of GSTM1 and CYP1A1 in Korean oral squamous cell carcinoma(SCC), (2) to associate oral SCC with the risk of these genetic polymorphisms. The genetic polymorphisms of the GSTM1 and the CYP1A1 genes among 50 Korean oral SCC were analyzed using polymerase chain reaction(PCR). The results suggest that the homozygote and the mutant type of CYP1A1 MspI polymorphisms may be associated with genetic susceptibility to oral SCC in Korean. A combination of the GSTM1 null type with the homozygote(m1/m1), and the mutant(m2/m2) type of CYP1A1 MspI polymorphisms showed a relatively high risk of oral SCC in Korean. In the smoking group, the GSTM1 wild genotype may be the high risk factor of oral SCC in Korean. These data coincide with the hypothesis which states that different susceptibility to cancer of genetic polymorphisms exist among different ethnic group and different types of human cancer.

• 대한치과교정학회지
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• 제40권5호
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• pp.334-341
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• 2010

본 연구의 목적은 한국인과 이집트인의 Angle씨 I급, II급, III급 부정교합군에서 하악치열궁의 크기와 형태적 특성을 상호 비교 분석하고자 하였다. 한국인 부정교합자 368명(114 Class I, 119 Class II, and 135 Class III)과 이집트인 부정교합자 94명(35 Class I, 32 Class II and 27 Class III)을 대상으로 하였다. 치료 전 하악 치열 모형을 복사한 사진에서 13개의 인접한 접촉면에서 가장 협측에 위치한 점들을 좌표화한 후 하악 치아의 두께 자료에 근거하여 임상브라켓 점들을 설정하였고 4개의 선 계측과 2개의 비율을 측정하였다. 치열궁 형태를 tapered, ovoid, squared의 3가지로 분류하여 두 인종 간 분포 특성에 관하여 비교하였다. 이집트인은 한국인보다 대구치 간 폭경과 견치 간 폭경이 유의성 있게 좁았으며 ($p$ < 0.001), 대구치 간 장경과 견치 간 장경이 더 짧았다 ($p$ < 0.001). 이집트인에서는 3가지의 치열궁 형태가 동등한 비율로 나타났으나 ($p$ = 0.46), 한국인에서는 square arch form (46.7%)이 가장 빈번하게 나타났고, tapered arch form이 가장 적게 나타났다(18.8%). 본 연구의 결과는 기성품의 초탄성 호선을 선택할 때 인종 간의 차이에 대한 유익한 정보를 제공할 수 있을 것으로 생각된다.

• 대한치과교정학회지
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• 제43권6호
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• pp.288-293
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• 2013

Objective: This study was aimed at comparing the mandibular arch forms of Korean and Vietnamese patients by using facial axis (FA) points on three-dimensional (3D) models. Methods: Mandibular casts of 68 Korean (Class I malocclusion, 30; Class II malocclusion, 38) and 78 Vietnamese (Class I malocclusion, 41; Class II malocclusion, 37) patients were scanned in their occluded positions and grouped according to arch form (tapered, ovoid, and square). The FA point of each tooth was digitized on the 3D mandibular models. The measurements and frequency distributions of the arch forms were compared between the ethnic groups. Results: The Vietnamese patients had significantly greater intercanine depth and intercanine and intermolar width-to-depth ratios than the Korean patients (p < 0.05). The frequency distributions of the arch forms were also significantly different (p = 0.038), but no sexual dimorphism was found. Conclusions: Vietnamese people tend to have deeper and wider arches than Korean people. The three arch forms are evenly distributed in Korean people, but Vietnamese people frequently have square arches. Clinicians should identify the correct arch form of an ethnic group before initiating orthodontic treatment.

• Toxicological Research
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• 제17권
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• pp.145-155
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• 2001

Cytochrome P4502C19 (CYP2C19) is one of human polymorphic xenobiotic-metabolizing enzymes. The enzyme has been reported to catalyze more than 70 substrates, involving more than 100 reactions. These include several classes of therapeutic agents (e.g. anti-microbial. cardiovascular, psycho-active, etc.), sex hormones and insecticides. Associations of the CYP2C19 genotype/phenotype with individual differences in drug efficacy (e.g. diazepam, omeprazole, proguanil) and toxicity (e.g. mephenytoin, barbiturates) have been documented by many investigators. At least 11 allelic variants of CYP2C19 gene were reported to date. Most of the mutant alleles found in the poor metabolizer (PM) led to the production of truncated and/or inactive proteins. Except for the exon 6, single-nucleotide mutations were reported in all nine exons of the gene. Genetic polymorphism of CYP2C19 shows marked interethnic variation with the population frequencies of PM phenotype ranging from 1∼2% up to more than 50%. The prevalence of CYP2C19 PM tends to be higher in Asian and certain Pacific Islanders than other race or ethnic specificity. Genotyping results of CYP2C19 also revealed that there are different proportions of individual mutant alleles among ethnic populations. This may, in part, explains the interethnic difference in the metabolism of certain drugs (i.e. diazepam), though they were from the same CYP2C19 phenotype. Recently, our research group has studied the genotype and phenotype of CYP2C19 and found that the PM frequency (7∼8%) in Thais is lower than other Asian populations. Molecular and clinical impacts of this finding warrant to further investigation.

• 한국콘텐츠학회논문지
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• 제9권5호
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• pp.1-12
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• 2009

올바른 피부색 검출은 사람의 얼굴 검출 및 동작 분석에서 매우 중요한 전처리과정에 속한다. 피부 검출은 일반적으로 화소의 칼라 공간을 Non-RGB로 변형하고, 피부색의 조명 요소를 제거한 다음 피부색 분포 모델에 의해 Skin과 Non-Skin으로 분류하는 3단계로 진행된다. 이는 피부색 검출이 칼라 공간, 조명 요소의 존재 여부, 피부 모델링 방법에 따라 수행 성능에 많은 영향을 받기 때문이다. 본 연구에서는 조명 조건에 따라 피부색 모델의 범위에 차이가 있다는 사실에 기초하여 다양한 조명 조건과 복잡한 배경을 가진 영상에서 효과적으로 다인종의 피부색을 분류해내 기 위한 3차원 피부색 모델을 제시하고자 한다. 제안된 피부색 모델은 화소의 칼라 공간을 YCbCr공간으로 변형하고, 각 요소(Y, Cb, Cr) 값에 의한 3차원 피부색 모델을 형성한다. 다인종의 피부색을 함께 분할하기 위해 인종(백인, 흑인, 황인)별 피부색 모델을 먼저 생성한 후 각각의 모델에서 피부색 확률에 따라 결합한 다인종을 위한 통합 모델을 생성하였다. 또한 우리는 적은 양의 훈련 데이터로 피부색 영역을 올바르게 검출할 수 있도록 여러 단계의 피부색 영역을 설정하였다.