• 한국임상약학회지
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• 제23권2호
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• pp.123-128
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• 2013

Purpose: The aim of study was to investigate the racial or ethnic differences in FDA-approved medications. Methods: Data on racial-based differences of drugs in PDR (Physician's Desk Reference) were analyzed by searching with keywords, "ETHNIC" and "RACE". Results: There were descriptions related to "ETHNIC" in product directions of 53 cases and "RACE" in 266 cases in 2010 PDR. After excluding 30 cases of duplicates, 289 cases were shown of which 28 cases were verified to demonstrate racial or ethnic differences. Drug category showing the higher racial or ethnic differences was cardiovascular drugs (7), followed by alimentary tract and metabolism drugs (6), nervous system drugs (5), and antineoplastic and immunomodulating agents (3). Pharmacokinetic differences between race and ethnicity were observed most frequently; differences in AUC or Cmax showed in 15 drugs and clearance differences in 7 drugs. Conclusions: This study identified the racial differences in medication usage in PDR. Therefore, the results can contribute to safe use of medication in real clinical settings in regards to the racial or ethnic differences.

• Genomics & Informatics
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• 제12권1호
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• pp.42-47
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• 2014

Asian populations contain a variety of ethnic groups that have ethnically specific genetic differences. Ethnic variants may be highly relevant in disease and human differentiation studies. Here, we identified ethnically specific variants and then investigated their distribution across Asian ethnic groups. We obtained 58,960 Pan-Asian single nucleotide polymorphisms of 1,953 individuals from 72 ethnic groups of 11 Asian countries. We selected 9,306 ethnic variant single nucleotide polymorphisms (ESNPs) and 5,167 ethnic variant copy number polymorphisms (ECNPs) using the nearest shrunken centroid method. We analyzed ESNPs and ECNPs in 3 hierarchical levels: superpopulation, subpopulation, and ethnic population. We also identified ESNP- and ECNP-related genes and their features. This study represents the first attempt to identify Asian ESNP and ECNP markers, which can be used to identify genetic differences and predict disease susceptibility and drug effectiveness in Asian ethnic populations.

• International Journal of Human Ecology
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• 제8권1호
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• pp.95-107
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• 2007

The present study examined generational differences in ethnicity maintenance among Korean-Chinese to understand the impact of recent social change on a Korean-Chinese ethnic community in China. A total of 1355 Korean-Chinese (557 parents and 798 children), who live in Shenyang, China, participated in this study. The subjects were asked about their language use during daily conversations and cultural activities. They were also asked about their ethnic identity and perceptions of social distance from Chinese people. The results reveal that the Korean-Chinese parent generation is more likely to maintain its ethnic language, while the child generation is more likely to maintain its ethnic culture. Second, more parents than children considered themselves as 'Korean-Chinese' rather than 'Chinese'. Third, members of the child generation show less social distance from Chinese people than do the parent generation. These results show a strong tendency towards ethnicity maintenance among Korean Chinese as well as recent changes in the community. This study argues for the importance of school education and school environment in maintaining the ethnic language and culture of Korean-Chinese children.

• 미국학
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• 제44권2호
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• pp.131-158
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• 2021

This paper examines how nation-specific history of Asian war brides affects different representations of war brides in Velina Hasu Houston's Tea (1984) and Julia Cho's The Architecture of Loss (2003). While war brides had long been excluded from American history, Japanese war brides were brought to public attention in the 1980s. Korean war brides, on the other hand, were kept out of sight until the 2000s. Focusing on how this time gap is related to ethnic difference, this paper analyzes dramaturgical differences between the two plays such as the presence/absence of war bride on stage or ethnic solidarity/familial reconciliation as the main device of war bride memorialization. Such differences, the paper suggests, stem from ethnic/historical differences between Korean and Japanese war brides. Through historical interpretations of the plays, this paper argues that America's military relationships with Korea and Japan were reproduced within the Asian-American families of each drama in ways that raise questions about pan-Asian identity.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.2879-2883
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• 2013

Objective: To investigate differences in mutations of epidermal growth factor receptor (EGFR) gene and relationships with clinicopathological features in patients with non-small cell lung cancer (NSCLC) between Uygur and Han ethnic groups. Methods: The Scorpions amplification refractory mutation system (Scorpions ARMS) was used to measure mutations in exons 18, 19, 20 and 21 of the EGFR gene in paraffin-embedded tumor tissue from NSCLC cases, and statistical analysis was performed to investigate links with clinicopathological features in different histological types of NSCLC. Results: Results from ARMS testing showed EGFR mutations in tumor tissues from six (6) of 50 NSCLC patients of Uygur ethnic group, with a positive rate of 12.0%; four of them (4) had exon 19 deletion in EGFR, and two (2) had L858R point mutation in exon 21 of EGFR. Statistically significant difference was noted in EGFR genetic mutation between adenocarcinoma and non-adenocarcinoma (P < 0.05), but no differences with gender, age group, smoking status, or stage (P > 0.05). EGFR mutations were detected in tumor tissues from 27 of 49 NSCLC patients of Han ethnic group, with a positive rate of 55.1%; 19 of them had exon 19 deletions, seven (7) had L858R point mutations in exon 21 of EGFR and one (1) had mutations in both exon 18 G719X and exon 20 T790M of EGFR. Statistically significant differences were noted in EGFR genetic mutations between genders and between adenocarcinoma and non-adenocarcinoma (P<0.05), but not with age group, smoking status, or stage (P > 0.05). Conclusion: Statistically significant differences were noted in the positive rates of EGFR genetic mutations in NSCLC patients between Uygur and Han ethnic groups, with lower positive rates for the Uygur cases.

• 아동학회지
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• 제26권5호
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• pp.31-38
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• 2005

This study investigated the performance of 346 students on the Reynold intellectual Assessment Scale scores for sex, ethnic, and socioeconomic differences. The sample consisted of 198 males and 148 females(271 White, 32 Black, 20 Hispanic, 8 Asian, and 15 others) who were referred for gifted evaluation. The findings indicated significant differences between the IQ scores with regard to sex, ethnicity, and socioeconomic status. Implications of these findings are discussed. in terms of assessing minority group members with the Reynolds Intellectual Assessment Scales (RIAS) to identify gifted children.

• 복식
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• 제56권2호
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• pp.112-124
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• 2006

Globally, several ethnic groups have expressed their spirit cultures based on their ethnic identity in diverse ways. Clothing has been one of the convenient objects to express ethnic identities. Therefore, patterns and colors used in traditional costumes have worked as a means to help understanding spirit cultures of ethnic groups. Since colors help strengthening solidarity of social members based on ethnic preference and community consensus, colors have performed a crucial role as a strategic tool in the fashion business closely related to consumers' individual characteristics. In survey results, color preferences of Korean and Italian specialists showed significant differences in signboard colors and disliked colors. Many Korean fashion specialists selected pink as a preferred color, black as a clothing color, red and white as a color with high visibility, and orange as a disliked color. In case of Italy, many specialists selected red and black as highly visible colors for a signboard, and green as a disliked color. In results comparing color preference for colors between Korean and Italian fashion design specialists, there were differences in color sensibility. Since this research used data from survey conducted using a very limited and much manipulated stimuli among a wide range of color schema and patterns, the study result may not be fully generalized. In future studies, more research using diversely segmented stimuli would be needed.

• 대한가정학회지
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• 제43권8호
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• pp.37-54
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• 2005

The purpose of this study is to provide basic information about the acculturation of Korean immigrants in China. A total of 459 Korean-Chinese from yanbian province, China and 768 Korean-Chinese from the city of Shenyang and Martin, China participated in this study. The subjects were asked about their language use during daily conversations and cultural activities using. The Cultural Life Style Inventory. Result indicated that overall Korean immigrants in China maintain their ethnic identity, ethnic language and culture. However, there were some differences in their levels of acculturation depending on the area they live and their educational levels. The differences were explained in part by the uniqueness of Yanbian province and a new policy for ethnic minorities in China. This study suggests that not only immigrants' demographic variables but also their ecological variables are important in understanding the acculturation of Korean immigrants in China.

• 한국식품영양학회지
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• 제28권6호
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• pp.1082-1089
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• 2015

The aim of this study was to investigate the effect of food neophobia on restaurant image, customer satisfaction, and loyalty in ethnic restaurants. A self-administered survey for data collection 581 customers who visited an ethnic restaurant in August, 2015. Statistical analyses included descriptive analysis, t-test, ANOVA and regression analysis for SPSS 21.0. The finding of the study indicated that the differences of food neophobia score in demographic characteristics showed significant differences by age, occupation, dining-out frequency, and source of dining-out information, not by gender. The mean value of food neophilic group was significantly higher than food neophobic group in all items of restaurant image, overall satisfaction and customer loyalty. The regression analysis showed that tangible aspect, price aspect, and food aspect of restaurant image had positive effects on overall satisfaction and customer loyalty however employee service showed different result by groups. The finding of the study offer marketing strategies for ethnic restaurants to induce customer revisit.

• Communications for Statistical Applications and Methods
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• 제26권1호
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• pp.1-9
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• 2019

Various probabilistic methods have been proposed for using interpopulation allele frequency differences to infer the ethnic group of a DNA specimen. The selection of the statistical method is critical because the accuracy of the statistical classification results vary. For the ancestry classification, we proposed a new ancestry evaluation method that estimate the combined ethnicity index as well as compared its performance with various classical classification methods using two real data sets. We selected 13 SNPs that are useful for the inference of ethnic origin. These single nucleotide polymorphisms (SNPs) were analyzed by restriction fragment mass polymorphism assay and followed by classification among ethnic groups. We genotyped 400 individuals from four ethnic groups (100 African-American, 100 Caucasian, 100 Korean, and 100 Mexican-American) for 13 SNPs and allele frequencies that differed among the four ethnic groups. Additionally, we applied our new method to HapMap SNP genotypes for 1,011 samples from 4 populations (African, European, East Asian, and Central-South Asian). Our proposed method yielded the highest accuracy among statistical classification methods. Our ethnic group classification system based on the analysis of ancestry informative SNP markers can provide a useful statistical tool to identify ethnic groups.