• Korean Journal of Clinical Pharmacy
• /
• v.24 no.1
• /
• pp.39-44
• /
• 2014

Purpose: To investigate adverse drug reactions (ADR) and causative drugs in the elderly 65 years of age or older, using Korean spontaneous reporting adverse events reporting database from June 2009 to December 2010. Methods: We estimated the association between ADRs and implicated medications by calculating a proportional reporting ratio (PRR), reporting odds ratio (ROR), and information component (IC). We reexamined the most frequently implicated medications and ADRs, and the seriousness of ADRs. Then, we assessed reports and concordant rate of ADRs due to medications designated as "high-risk" in elderly by 2012 healthcare effectiveness data and information set (HEDIS) or "potentially inappropriate" by 2012 American Geriatrics Society updated Beers criteria for potentially inappropriate medications (PIMs). Results: Among 15,484 elderly reports, data-mining analysis by PRR, ROR and IC showed that 421 drug-ADR pairs were detected as signals (3,189). The most frequently reported ADR and causative drug were urticaria (470) and contrast media agents (647), respectively. One hundred eighty nine ADR cases were graded as serious. Twenty-two kinds of high-risk medications were shown to be implicated in only 0.9% of ADRs. Only thirty-nine cases were consistent with 2012 Beers criteria or HEDIS. Conclusion: These results suggest that management of the other medications including contrast media agents as well as close monitoring of PIMs are necessary for reducing ADRs in the elderly.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.45 no.2
• /
• pp.65-73
• /
• 2008

The characterization process for the accurate color reproduction in mobile phone with camera and LCD is popular. The camera and LCD characterization, gamut mapping process is necessary to map the camera's input color stimulus, CIEXYZ value, into the LCD's output color stimulus. Each characterization is the process estimating the relation between input and output signals. In case of LCD, because of output device, the output color stimulus for the arbitrary input signal can be measured by spectro-radiometer However, in the camera, as the input device, the characterization is an inaccurate and needs the manual works in the process obtaining the output signal because the input signal can not be generated. Moreover, after gamut mapping process, the noise is increased because the optimized gamma tone curve of camera for the noise is distorted by the characterization. Thus, this paper proposed the system of obtaining the output signal of camera and the method of gamma correction for the noise. The camera's output signal is obtained by RGB values of patches from captured the color chart image. However, besides the illumination, the error for the location of the chart in the viewfinder is generated when many camera modules are captured the chart. The method of correcting the position to correct the error from manual works. The position of camera is estimated by captured image. This process and moving of camera is accomplished repeatedly, and the optimized position can be obtained. Moreover, the lightness curve of camera output is corrected partly to reduce the noise from the characterization process.

• The Journal of the Acoustical Society of Korea
• /
• v.32 no.6
• /
• pp.548-555
• /
• 2013

The localization of sources has a numerous number of applications. To estimate the position of sources, the relative delay between two or more received signals for the direct signal must be determined. Although the generalized cross-correlation method is the most popular technique, an approach based on eigenvalue decomposition (EVD) is also popular one, which utilizes an eigenvector of the minimum eigenvalue. The performance of the eigenvalue decomposition (EVD) based method degrades in the low SNR and the correlated environments, because it is difficult to select a single eigenvector for the minimum eigenvalue. In this paper, we propose a new adaptive algorithm based on Canonical Correlation Analysis (CCA) in order to extend the operation range to the lower SNR and the correlation environments. The proposed algorithm uses the eigenvector corresponding to the maximum eigenvalue in the generalized eigenvalue decomposition (GEVD). The estimated eigenvector contains all the information that we need for time delay estimation. We have performed simulations with uncorrelated and correlated noise for several SNRs, showing that the CCA based algorithm can estimate the time delays more accurately than the adaptive EVD algorithm.

• Progress in Medical Physics
• /
• v.10 no.1
• /
• pp.23-32
• /
• 1999

Combined MRI and Relaxogram approach was introduced as a very useful tool for fat study. The phantoms simulating homogeneous mixture of fat and non-fat environments were measured with spin echo pulse sequence on a 0.15 T whole body imager. From 45 scans, the Tl values were obtained by fitting the data to continuous distribution (CONTIN) of relaxation time. This relaxogram gives broad distributions of relaxation time, which are characterized by a number of peaks with characteristic T1 values. Two distinct peaks in relaxogram were observed and identified as signals from com oil and gelatin gel. This model system can be served as simulating the distribution of fat in muscle. Also the relative ratio of two components, which is proportional to the area under the peak, is estimated and compared to nominal values. Based on the good agreement between two predictions, the values from our proposed method agreed with nominal values within $\pm$7 % error. The effects of different concentration of contrast agent and different region of interest are presented. To optimize total scan times, the minimum required data points and so further reduction in total scan times are discussed.

• KIPS Transactions on Software and Data Engineering
• /
• v.2 no.9
• /
• pp.603-614
• /
• 2013

The popularity of mobile devices provides their users with a circumstance that services and information can be accessed wherever and whenever users need. Accordingly, various studies have been proposed personalized methods to improve accessibility of mobile users to information. However, since these personalized methods require users' private information, they gives rise to problems on security. An efficient way to resolve security problems is to estimate user information by using their online and offline behavior. In this paper, for this purpose, it is proposed a novel user information identification system that identifies users' personal and social information by using both his/her behavior on social network services and proximity patterns obtained from GPS data. In the proposed system, personal information of a user like age, gender, and so on is estimated by analyzing SNS texts and POI (Point of Interest) patterns, while social information between a pair of users like family and friend is predicted with proximity patterns between the users. Each identification module is efficiently designed to handle the characteristics of user data like much noise in SNS texts and missing signals in GPS data. In experiments to evaluate the proposed system, our system shows its superiority against ordinary identification methods. This result means that the proposed system can efficiently reflect the characteristics of user data.

• Journal of Korean Society for Geospatial Information Science
• /
• v.23 no.4
• /
• pp.43-48
• /
• 2015

We studied on pseudo-range correction(PRC) modeling in order to improve differential GNSS(DGNSS) accuracy. The PRC is the range correction information that provides improved location accuracy using DGNSS technique. The digital correction signal is typically broadcast over ground-based transmitters. Sometimes the degradation of the positioning accuracy caused by the loss of PRC signals, radio interference, etc. To prevent the degradation, in this paper, we have designed a PRC model through polynomial curve fitting and evaluated this model. We compared two quantities, estimations of PRC using model parameters and observations from the reference station. In the case of GPS, the average is 0.1m and RMSE is 1.3m. Most of GPS satellites have a bias error of less than ${\pm}1.0m$ and a RMSE within 3.0m. In the case of GLONASS, the average and the RMSE are 0.2m and 2.6m, respectively. Most of satellites have less than ${\pm}2.0m$ for a bias error and less than 3.0m for RMSE. These results show that the estimated value calculated by the model can be used effectively to maintain the accuracy of the user's location. However;it is needed for further work relating to the big difference between the two values at low elevation.

• Journal of Biomedical Engineering Research
• /
• v.25 no.2
• /
• pp.119-127
• /
• 2004

In this paper, an automatic external biphasic defibrillator that removes ventricular fibrillation efficiently with a low discharging energy has been developed. The system is composed of software including a fibrillation detection algorithm and a system control algorithm, and hardware including a high voltage charging/discharging part and a signal processing part. The stability of the developed system has been confirmed through continuous charging/discharging test of 160 times and the detection capability of the real-time fibrillation detection algorithm has been estimated by applying a total of 30 various fibrillation signals. In order to verify the clinical efficiency and safety, the system has been applied to five pigs before and after fibrillation inductions. Also, we have investigated the system efficiency in removing fibrillation by applying two different discharging waveforms, which have the same energy but different voltage levels.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.14 no.6
• /
• pp.171-178
• /
• 2010

Pipeline structure is one of core underground infrastructure which transports primary sources. Since the almost pipeline structures are placed underground and connected each other complexly, it is difficult to monitor their structural health condition continuously. In order to overcome this limitation of recent monitoring technique, recently, a Ubiquitous Sensor Network (USN) system based on on-line and real-time monitoring system is being developed by the authors' research group. In this study, real-time pipeline health monitoring (PHM) methodology is presented based on electromechanical impedance methods using USN. Two types of damages including loosened bolts and notches are artificially inflicted on the pipeline structures, PZT and MFC sensors that have piezoelectric characteristics are employed to detect these damages. For objective evaluation of pipeline conditions, Damage metric such as Root Mean Square Deviation (RMSD) value was computed from the impedance signals to quantify the level of the damage. Optimal threshold levels for decision making are estimated by generalized extreme value(GEV) based statistical method. Throughout a series of experimental studies, it was reviewed the effectiveness and robustness of proposed PHM system.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.10 no.2
• /
• pp.302-311
• /
• 1999

In this paper, in order to suggest an optimal polarization diversity composition method in indoor radio wave propagation environments, the variation of the cross polarization discrimination(XPD) was theoretically analyzed by a computer simulation and compared to the actual measured data. From the results, it can be seen that the cross polarization discrimination of the case, a circularly polarized antenna was used at the transmitting end as well as the vertical and horizontal polarized antenna branches were used at receiving end (CV-CH), is lower than that of the case, horizontal polarized antenna at the transmitting end as well as the horizontal and vertical polarized antenna branches at the receiving end(HH-HV), and that of the case, vertical polarized antenna at the transmitting end as well as the vertical and horizontal polarized antenna branches at the receiving end(VV-VH). In this paper, to get more effective CV-CH polarization diversity composition, the amount of cross polarization discrimination values at the signals received by horizontal polarized antenna is compensated and the polarization diversity effect through the cumulative probability distribution is estimated. From the evaluation results, it was found that the polarization diversity effect was better at the compensated case than at the uncompensated case. On the other hand, it can be known that the polarization diversity effect is getting better as the cross polarization discrimination values are getting lower, and also be known that the effect can be improved if a transmitting antenna is composed of the ellipse polarized antenna by adjusting the axial ratio of the circularly polarized antenna and, a receiving antenna is made up of the vertical and horizontal polarized antenna branches.

• Journal of the Institute of Convergence Signal Processing
• /
• v.9 no.1
• /
• pp.24-30
• /
• 2008

In this paper we analyze the performance of an adaptive sector cell system, which is adopted to maintain the traffic balance between sectors and to utilize the cell resources effectively, using the data collected from real channel environments. In the data measurements, we transmitted the QPSK modulated signal with carrier frequency of 1.95GHz and received the signals using the 8x4 array antenna equipped on the top of buildings in the urban area. We analyzed the angular distribution and the delay spread of a user signal and analyzed angular distribution of mobile users in a cell using the collected data. Also, we propose the vector channel modeling using the estimated pdf(probability distribution function) of the analyzing results. Through the proposed channel modeling the improvement of the call blocking rate was analyzed when using the adaptive sector cell system, and computer simulations show that the call blocking rate of the adaptive sector cell system was much lower than that of the fixed sector cell system. Additionally, it shows that the call blocking rate increases severely in the fixed sector cell system while the difference of the call blocking rate was smaller in the adaptive sector cell system, as the user density of the spatial distribution increases.