• Journal of Korean Neurosurgical Society
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• v.47 no.4
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• pp.282-286
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• 2010

Objective : The aim of the present study was to assess the effect of lumbar disc herniation surgery for low back pain on the erectile functioning. Methods : Thirty-eight patients, with age ranging from 22 to 56 years, who had presented with pain due to herniated lumbar discs were included in the study. International Index of Erectile Function (IIEF) Short Form questionnaire was used to evaluate the erectile functioning. Patient visits on the 1st week,1st month and 3rd month postoperatively were analyzed. Pain scores were also noted together with side effects and the complications of the surgery. Results : Of the 38 patients, 18 patients had reported erectile dysfunction; 10 patients mild and 8 patients moderate erectile dysfunction. Twenty patients did not report erectile problems. The herniation levels mostly were L5-S1 in 12 (31.6%). Overall, erectile dysfunction rates have improved in 31.7% of those previously with erectile dysfunction in a 3 month period after the surgery. Best results were obtained in those patients with mild erectile dysfunction preoperatively. Conclusion : Mild erectile dysfunction together with radiculopathy tends to improve after lumbosacral disc surgery. Moderate and severe erectile dysfunction may be related to a more severe nerve injury or to vascular and/or psychiatric factors. An evaluation of erectile functioning should routinely be performed in patients with lumbosacral disc disease both for data accumulation and for medico legal causes since the documentation of the correlation between erectile dysfunction and lumbosacral disc disease is still lacking.

• The Journal of Korean Medicine
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• v.17 no.2 s.32
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• pp.73-87
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• 1996

Erectile dysfunction is defined as the inability to attain and maintain penile rigidity sufficient to allow sexual intercourse. Although erectile dysfunction is usually considered a benign disorder, it has a dramatic impact on quality of life of the patients as well as their sexual partners. And it is common in men between the age of 40 and 70 years, and its incidence increases with age. The prevalence is reported to occupy 10% at the age of 40 years, 20% in 50s, 30% in 60s and 50% at the age of 70 years, and is more prevalent as stress in modern life and interest onsexual behavior increase. This article has aims to investigate and summarize the current trend of treatment for erectiledysfunction so as to suggest the effective and available way to treat the disease. In oriental medicine, erectile dysfunction has been treated with herb medicine and acupuncture with good results. Some of herb drugs have the substances which induce penile erection. So it should be investigated on the neurotransmitter or endothelial mediator which can be included in herb drugs. The acupuncture therapy stimulates the erectile nerves and is reported to be effective for erectile dysfunction. And suppository, locus injection therapy and topical agent are found to be effective as well as stellate ganglion block and biofeedback treatment. So the study on the approach and application of these treatments on erectile dysfunction would be necessary.

• The Journal of Internal Korean Medicine
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• v.22 no.3
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• pp.431-436
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• 2001

Objective : Erectile dysfunction is defined as the inability to attain and maintain penile rigidity sufficient to allow sexual intercourse. Although erectile dysfunction is usually considered a benign disorder, it has a dramatic impaction quality of life of the patient as well as their sexual partners. we carried out 2 cases of erectile dysfunction patient with cerebral infarction in past history. Method : 2 patients with erectile dysfunction were included in this study. Each patient was treated with palmigihwang-tang and acupuncture. The erection was evaluated clinically by manual palpation and estimated on a 5-point scale as no response, some enlargement, full, enlargement, erection sufficient for intercourse, and full rigidity, In addition ,each patient assessed his satisfaction with the treatment using a 3-point scale as poor, fair, or good Result : 2 cases patients with erectile dysfunction was improved full rigidity by treatment of using palmigihwang-tang and acupunction. Satisfaction with the treatment was reported Good. Conclusion : Treatment of using Palmigihwang-tang and acupuncture was highly effective at producing an erection satisfaction for vaginal intercourse.

• Korean Journal of Plant Resources
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• v.31 no.2
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• pp.109-116
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• 2018

Erectile dysfunction (ED), also known as impotence, is the inability to attain and sustain an erection firm enough to have sexual intercourse. Frequent ED may be a symptom of health problems including heart disease, obesity, alcoholism, stress, smoking, and depression, that need treatment. This study aimed to effect of complex extract (CPL) including Cornus officinalis on sexual function factor in the erectile dysfunction rat model. The erectile dysfuction rat model was induced by cimetidine (500 mg/kg in 5% ethanol, oral injection 2 weeks). Rats were oral administered with different concentration of CPL in rat erectile dysfunction model. As a results, sexual function factors (NO, cGMP) significantly improved in CPL treated groups (CPL-300, 600, 900 mg/kg) compared to CON group. Serum testosterone was increased in a dose-dependent manner after CPL treatment. Furthermore, administrations of CPL restored lumen areas of the prostate in the erectile dysfunction rat model. These results indicated that CPL alleviated erectile dysfunction by increasing sexual function factor and testosterone in rat model. CPL could be used to natural treatement for erectile dysfunction. However, further study is required to identify active ingredient and its mechanism of erectile dysfunction.

• The Journal of Internal Korean Medicine
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• v.22 no.4
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• pp.627-631
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• 2001

Objective : Infrared thermal image is usually utilized for the diagnotic value of verious disease. We investigated the penile temperature of erectile dysfunction patient. Methods : We mesured the thermal difference of penile infrared thermal image in erectile dysfunction patient group and control group. Results : 1. Patient group's thermal degree is lower than Control group's in Kwanwon, Left scrotum, medial part of thigh. 2. The Kwanwon's temperature is especially showed lower than other mesured point's in erectile dysfunction patient group. Conclusion : According to the above results, it could be suggested that penile infrared image help us diagnostic value of erectile dysfunction patient.

• Korean Journal of Adult Nursing
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• v.25 no.5
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• pp.483-493
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• 2013

Purpose: The purpose of this study was to examine late-onset hypogonadism, erectile dysfunction, depression, and quality of life among middle-aged male workers. Methods: The subjects included 343 men aged between 40 and 64, responded to self-report questionnaires on general characteristics, late-onset hypogonadism, erectile dysfunction, depression, and quality of life. Data were collected from May 16, 2012 to October 9, 2012 and analyzed using t-test, ANOVA, $x^2$-test, hierarchical multiple regression. Result: The prevalence rate of late-onset hypogonadism was 63.8% with high points in reduction of libido, energy, physical strength and endurance, and erectile function. There were significant differences in late-onset hypogonadism according to age($x^2$=8.98, p=.048) and in erectile dysfunction according to age(F=11.03, p<.001), monthly income(F=2.84, p=.024) and smoking( t=2.96, p=.018). Significant differences were also found in depression according to educational level(F=8.12, p<.001) and in quality of life according to monthly income(F=7.21, p<.001). The factors which influenced quality of life were late-onset hypogonadism, erectile dysfunction, depression, marital status and religion. Conclusion: Symptoms of erectile dysfunction can be improved by smoking cessation education program. In order to improve the life quality of middle-aged men, nursing intervention programs that would both provide proper knowledge on climacteric syndrome and alleviate symptoms should be designed while, at the same time, other programs to evaluate, prevent and control depression are developed.

• Korean Journal of Exercise Nutrition
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• v.25 no.1
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• pp.30-34
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• 2021

[Purpose] Many studies have observed a high prevalence of erectile dysfunction among individuals performing physical activity in less leisure-time. However, this relationship in patients with type 2 diabetic patients is not well studied. In exposure outcome studies with ordinal outcome variables, investigators often try to make the outcome variable dichotomous and lose information by collapsing categories. Several statistical models have been developed to make full use of all information in ordinal response data, but they have not been widely used in public health research. In this paper, we discuss the application of two statistical models to determine the association of physical inactivity with erectile dysfunction among patients with type 2 diabetes. [Methods] A total of 204 married men aged 20-60 years with a diagnosis of type 2 diabetes at the outpatient unit of the Department of Endocrinology at PSG hospitals during the months of May and June 2019 were studied. We examined the association between physical inactivity and erectile dysfunction using proportional odds ordinal logistic regression models and continuation ratio models. [Results] The proportional odds model revealed that patients with diabetes who perform leisure time physical activity for over 40 minutes per day have reduced odds of erectile dysfunction (odds ratio=0.38) across the severity categories of erectile dysfunction after adjusting for age and duration of diabetes. [Conclusion] The present study suggests that physical inactivity has a negative impact on erectile function. We observed that the simple logistic regression model had only 75% efficiency compared to the proportional odds model used here; hence, more valid estimates were obtained here.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1164-1169
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• 2002

The purpose of this study was to examine the correlation of chronic prostatitis with sexual dysfunction and WBC counts on expressed prostatic secretion(EPS) with symptoms of sexual dysfunction. From 2001. 9. 1 to 2002. 3. 31, chronic prostatitis patients(30 examples) treated for more than 4 weeks were compared with normal group(30 examples) about hypoactive sexual desire disorder, erectile dysfunction, orgasmic disorder and hematospermia. We investigated sexual dysfunction according to the degree of prostatitis, improvement rate of prostatitis and sexual dysfunction. Chronic prostatitis patients compared with normal group were increased significantly in decreased libido(73.3%), erectile dysfunction(51.1%), orgasmic disorder(48.7%) and hematospermia(16.7%). In WBC very many/HPF group compared with others. though sexual dysfunction was highly revealed, but there was no statistic significance. In improvement rate of prostatitis, total improvement rate was 76.7%, WBC 10-30/HPF group 77.8%, WBC many/HPF group 72.8% and WBC very many/HPF group 80%. But the medical cure effect was the highest in WBC 10-30/HPF group. In the improvement rate of sexual dysfunction, total improvement rate was 68.5%, hematospermia 100%, decreased libido 90.9%, erectile dysfunction 67.4% and orgasmic disorder 60.3%. As a result of considering the relation with improvement rate of prostatitis and sexual dysfunction, there was a statistical significance at the erectile dysfunction. orgasmic disorder. The results showed the chronic prostatitis had effects on sexual dysfunction but there was no correlation between the degree of chronic prostatitis with sexual dysfunction. It also showed that the treatment of prostatitis had effects on improvements of erectile dysfunction and orgasmic disorder.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.202-202
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• 2002

DA-8159, a new pyrazolopyrimidinone derivative for erectile dysfunction, was administered by gavage at levels of 0, 17.5, 70, and 280 mg/mg to Sprague-Dawley male rats from 28 days before mating to the end of mating period, and to remales from 14 days before mating to day 6 of gestation.(omitted)

• Journal of Pharmacopuncture
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• v.27 no.2
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• pp.82-90
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• 2024

Objectives: Nitric oxide is the most important mediator of penile erection after the onset of sexual excitement. It activates cyclic guanosine monophosphate (cGMP), increasing penile blood flow. Most pharmaceutical medications prevent enzyme phosphodiesterase type 5 (PDE-5) from breaking down cGMP, thus keeping its level high. However, due to the adverse effects of pharmacological therapies, herbal drugs that improve sexual function have gained attention recently. This study aimed to investigate the combined effects of ginseng, Tribulus terrestris, and L-arginine amino acid on the sexual performance of individuals with erectile dysfunction (ED) using the 5-item version of the International Index of Erectile Function (IIEF-5) questionnaire. Methods: Over three months, 98 men with erectile dysfunction were randomly assigned to receive either 500 mg of herbal supplements or placebo pills. Each herbal tablet contained 100 mg of protodioscin, 35 mg of ginsenosides, and 250 mg of L-arginine. Results: The results showed that the changes in the average scores of ILEF-5 within each group before and after the intervention indicated that all parameters related to the improvement of sexual function in patients with erectile dysfunction improved in the herbal treatment group (p < 0.001). The herbal group significantly improved IIEF-5 scores in nondiabetics (p < 0.05). However, there was no significant difference in the changes of IIEF-5 scores between the two intervention and control groups in diabetic patients. Conclusion: In conclusion, ginseng, Tribulus terrestris, and L-arginine have properties that increase energy and strengthen sexual function, making them suitable for patients with sexual disorders.