• Pediatric Infection and Vaccine
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• 제18권2호
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• pp.201-206
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• 2011

목 적 : 본 연구는 균혈증이 발생한 소아암 환자의 임상 양상을 분석하고자 실시하였다. 방 법: 2008년 1월부터 2010년 10월까지 삼성서울병원에 입원한 소아암 환자에서 발생한 균혈증 예를 후향적으로 분석하였다. 조혈모세포 이식 환자는 제외하였다. 결 과:총 141예의 양성 혈액 배양 검사 중 오염균을 제외한 108명의 환자 128예의 혈액 배양 양성 결과를 분석하였다. 그람 양성균은 60예, 그람 음성균은 68예에서 동정되었고 균혈증의 원인은 21.1%에서 확인되었다. 중심정맥관 연관 균혈증은 9.4% (12/128예)에서 발생하 였고, 그람 양성균의 빈도가 75% (9/12회)로 관찰되었다. 쇼크가 10예(7.8%)에서 발생하였으며 그람 음성균의 빈도가 80% (8/10회)였다. 균이 음전된 후 30일 내에 균혈증이 재발한 환자가 2명 있었고 균혈증 관련 사망예는 없었다. 결 론 : 소아암 환자의 균혈증 치료에 있어서 알맞은 치료 지침을 위하여 지속적인 모니터링이 필요하다.

• 한국과학교육학회지
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• 제25권2호
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• pp.98-110
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• 2005

본 연구의 목적은 과학교사들이 겪는 과학 교수 학습의 딜레마 일화를 교사교육에 활용하는 방안 및 의의를 탐색하는 것이다. 즉, 과학 교수-학습의 딜레마 일화와 이를 활용한 토론 수업에 대한 교사들의 반응을 조사하여, 교사교육에서 딜레마 상황을 도입하는 것에 대한 의의를 탐색하고 이를 바탕으로 딜레마 일화의 교사교육 활용 방안을 제안하고자 하였다. 이를 위하여 초등 교사 11명을 대상으로 대학원 수업 과정에서 Wallace와 Louden(2002)의 책에 제시된 딜레마 일화를 도입한 토론 수업을 실시하면서, 제시된 딜레마 일화의 현실성과 중요성에 대한 교사들의 인식과, 딜레마 일화를 활용하는 토론 수업에 대한 교사들의 의견을 조사하였다. 이러한 연구는 교사교육에 대한 구성주의적 입장을 바탕으로 하고 있으며, 해가 하나로 주어지지 않는 딜레마 상황이 교사에게 과학 교수-학습에 대한 개방적 탐구의 기회로, 과학교육의 본성에 대한 이해를 높이는 기회로 작용할 수 있다는 생각에 기초한다. 딜레마 일화의 현실성과 중요성에 대한 인식은 각 주제별로 차이가 있었으나 특히 유사 경험이 많고 현실성과 중요성이 높게 인식된 주제는 '교과서', '실험 활동', '과학 법칙', '교사의 권위', '공평', '성별 차', '과학의 본성' 등이었다. 교사들은 이러한 딜레마 일화에 대한 토론 수업이 자신의 수업을 반성적으로 고찰할 수 있는 기회를 제공하며, 다른 교사들과 유사한 경험을 공유할 수 있고, '과학교육'을 전체적으로 조망할 수 있다는 점을 장점으로 인식하였다. 또한 교사 대부분은 이러한 딜레마 상황을 교사교육에 도입하는 것에 대해 긍정적인 의견을 제시하여 교사교육에서 딜레마 일화를 도입, 활용하는 것에 대한 가능성과 유용성을 보여 주었다. 위와 같은 탐색적인 연구로부터 얻은 교사들의 반응과 연구자의 토론 수업 경험을 바탕으로 과학 교사교육에서 딜레마 일화의 활용 방안을 제안하였으며 딜레마 일화 활용 시 문제점을 고찰하였다.

• 한국습지학회지
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• 제10권2호
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• pp.143-153
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• 2008

본 논문의 목적은 ENSO의 영향에 의한 우리나라 강우의 확률빈도와 공간분포 특성을 분석하는 것이다. 따라서 우리나라 기상관측소의 강우량 자료를 Warm(El Nino), Cold(La Nina), Normal 에피소드에 따라 기간별로 분류하였다. 또한 이렇게 분류한 자료는 Markov Chain 모형을 이용하여 100년의 자료로 모의 발생하였고 에피소드별로 빈도분석을 실시하였다. 빈도분석 결과 에피소드에 따라 각 기상관측소별로 강우의 크기에 영향을 미치고 있음을 알 수 있었다. 또한 군집분석을 실시하여 각 에피소드의 공간적인 영향에 대해서 분석하였다. 결과적으로 Warm(El Nino), Cold(La Nina) and Normal 에피소드로 대표되는 ENSO는 우리나라 강우의 확률빈도과 공간분포에 크게 영향을 미치는 것으로 파악되었다.

• 성인간호학회지
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• 제21권1호
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• pp.105-116
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• 2009

Purpose: The purpose of the study was to describe nonverbal behaviors of nurses in communication with patients with dementia in an elderly care institution in Korea. Methods: Conversation analysis was utilized to analyze the data which were collected using video camera to capture non-verbal as well as verbal behaviors. A total of 66 episodes of everyday conversations were analyzed using seven nonverbal categories: affirmative head nodding; illustrative gestures; patient-directed eye gaze; smiling and/or laughing; forward leaning; affective touch; and instrumental touch. Results: Among seven categories, patient-directed eye gaze(94%) was the most frequently utilized among nurses followed by affirmative head nodding(67%) and forward leaning(67%), while smiling was the least used(32%). Affective touch was identified in 39 episodes(59%). Among them, the most frequently touched area was hand or handshaking(59%) followed by shoulder or back, arm, and face. There were wide differences among nurses in terms of using affective touch, ranging from 0% to 98%. Nonverbal behaviors were more frequently identified in effective episodes than in ineffective episodes. Conclusion: Actively utilizing effective nonverbal behaviors may help geriatric nurses in promoting communication and in establishing rapport with patients with dementia.

• Journal of Preventive Medicine and Public Health
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• 제52권1호
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• pp.41-50
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• 2019

Objectives: The aim of this study was to investigate cancer patients' utilization of tertiary hospitals in Seoul before and after the benefit expansion policy implemented in 2013. Methods: This was a before-and-after study using claims data of the Korean National Health Insurance Service from 2011 to 2016. The unit of analysis was inpatient episodes, and inpatient episodes involving a malignant neoplasm (International Classification of Diseases, Tenth Revision codes: C00-C97) were included in this study. The total sample (n=5 565 076) was divided into incident cases and prevalent cases according to medical use due to cancer in prior years. The tertiary hospitals in Seoul were divided into two groups (the five largest hospitals and the other tertiary hospitals in Seoul). Results: The proportions of the incident and prevalent episodes occurring in tertiary hospitals in Seoul were 34.9% and 37.2%, respectively, of which more than 70% occurred in the five largest hospitals in Seoul. Utilization of tertiary hospitals in Seoul was higher for inpatient episodes involving cancer surgery, patients with a higher income, patients living in areas close to Seoul, and patients living in areas without a metropolitan city. The utilization of the five largest hospitals increased by 2 percentage points after the policy went into effect. Conclusions: The utilization of tertiary hospitals in Seoul was concentrated among the five largest hospitals. Future research is necessary to identify the consequences of this utilization pattern.

• Journal of Yeungnam Medical Science
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• 제33권2호
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• pp.105-111
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• 2016

Background: Neutropenic fever is one of the most common and potentially severe complications of chemotherapy in pediatric oncology patients, while urinary tract infection (UTI) is one of the most prevalent bacterial infections in these patients. Therefore, this study was conducted to investigate features of UTI with neutropenic fever in pediatric oncology patients. Methods: We retrospectively reviewed and analyzed the medical records, laboratory results and image findings of cases of neutropenic fever in the Department of Pediatrics of Yeungnam University Medical Center, South Korea between November 2013 and May 2015. Episodes were divided into two groups, UTI vs. non-UTI group according to the results of urine culture. The results were then compared between groups. The analysis was performed using IBM SPSS 23.0. A p-value <0.05 was considered to indicate a significant difference between groups. Results: Overall, 112 episodes of neutropenic fever were analyzed, among which 22 episodes (19.6%) showed organisms on urine culture and were classified as UTI. The remaining 90 episodes were classified as non-UTI. Only four episodes (18.2%) of the UTI group showed pyuria on urine analysis. In the UTI group, 76.5% were sensitive to the first line antibiotics and showed higher clinical response than the non-UTI group. Among hematologic malignancy patients, the UTI group revealed higher serum ${\beta}2$-microglobulin levels than the non-UTI group ($1.56{\pm}0.43mg/L$ vs. $1.2{\pm}0.43mg/L$, p<0.028). Conclusion: UTI in pediatric neutropenic fever responds well to antibiotics. Hematologic malignancy cases with UTI reveal increased serum ${\beta}2$-microglobulin level. These results will be helpful to early phase diagnosis of UTI.

• 한국대기환경학회지
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• 제15권4호
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• pp.441-455
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• 1999

Meteorological characteristics of three high-ozone episodes in the Greater Seoul Area, selected on the basis of morning-average wind direction and speed for the 1990~1997 period, were investigated. Three high-ozone episodes thus selected were seven days of July 3~9, 1992, nine days of July 21~29, 1994, and three days of August 22~24, 1994. Along with surface meteorological data from the Seoul Weather Station, surface and 850-hPa wind fields over the Northest Asia around the Korean Peninsula were used for the analysis. In the July 1992 episode, westerly winds were most frequent as a result of the influence of a high-pressure system in the west behind the trough. In contrast, in the July 1994 episode, easterly winds were most frequent due to the effect of a typhoon moving north from the south of Japan. Despite different prevailing wind directions in the two episodes, the peak ozone concentration of each episode always occurred when a sea-land breeze developed in association with weak synoptic forcing. The August 1994 episode, selected as being representative of calm conditions, was another typical example in which peak ozone concentration rose to 322 ppb under the well-developed sea-land breeze. All three high-ozone episodes were terminated by precipitation, and subsequent rises in ozone concentrations were also suppressed by a series of precipitation afterwards. In particular, two heavy rainfalls were the main reason why the August 1994 episode, with the highest and second-highest ozone concentrations during the 1990~1997 period, lasted for only a few days.

• The Korean Journal of Physiology and Pharmacology
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• 제25권4호
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• pp.281-296
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• 2021

The beneficial effects of hypoxic preconditioning are abolished in the diabetes. The present study was designed to investigate the protective effects and mechanisms of repeated episodes of whole body hypoxic preconditioning (WBHP) in db/db mice. The protective effects of preconditioning were explored on diabetes-induced vascular dysfunction, cognitive impairment and ischemia-reperfusion (IR)-induced increase in myocardial injury. Sixteen-week old db/db (diabetic) and C57BL/6 (non-diabetic) mice were employed. There was a significant impairment in cognitive function (Morris Water Maze test), endothelial function (acetylcholine-induced relaxation in aortic rings) and a significant increase in IR-induced heart injury (Langendorff apparatus) in db/db mice. WBHP stimulus was given by exposing mice to four alternate cycles of low (8%) and normal air O₂ for 10 min each. A single episode of WBHP failed to produce protection; however, two and three episodes of WBHP significantly produced beneficial effects on the heart, brain and blood vessels. There was a significant increase in the levels of brain-derived neurotrophic factor (BDNF) and nitric oxide (NO) in response to 3 episodes of WBHP. Moreover, pretreatment with the BDNF receptor, TrkB antagonist (ANA-12) and NO synthase inhibitor (L-NAME) attenuated the protective effects imparted by three episodes of WBHP. These pharmacological agents abolished WBHP-induced restoration of p-GSK-3β/GSK-3β ratio and Nrf2 levels in IR-subjected hearts. It is concluded that repeated episodes of WHBP attenuate cognitive impairment, vascular dysfunction and enhancement in IR-induced myocardial injury in diabetic mice be due to increase in NO and BDNF levels that may eventually activate GSK-3β and Nrf2 signaling pathway to confer protection.

• 아동학회지
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• 제30권2호
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• pp.145-159
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• 2009

In this study, mothers of 205 4- to 5-year-old preschoolers responded to aggression episodes of Werner et al. (2006); preschoolers' teachers responded to the Preschool Social Behavior Scale (Crick et al., 1997). Results showed, (1) boys exhibited more overt and relational aggression. (2) In overt aggression episodes, mothers used encouragement to boys and rule violation responses to girls; in relational aggression episodes, mothers used encouragement and power assertion responses to girls. (3) Mothers' power assertion about overt aggression related negatively with preschoolers' overt aggressive behaviors; mothers' discussion about relational aggression related positively with preschoolers' overt aggressive behaviors. Implications of these findings for the mothers' responses by aggression types were discussed in order in better understand preschooler's aggressive behaviors.

• 대한수학교육학회지:학교수학
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• 제4권4호
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• pp.657-675
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• 2002

This paper is to make strides toward an enriched understanding of the difficulties and issues raised by applying the 7th mathematics curriculum to elementary school classrooms. A general overview of the curriculum is presented in line with teaching and learning methods emphasized in the curriculum. Four classroom episodes are presented in brief in order to diagnose the problems in situating the curriculum in elementary mathematics classrooms. These episodes deal with lessons emphasizing activity rather than its associated concepts or principles, overusing multimedia data, pursuing play rather than its associated thinking, and distributing various individual worksheets in the name of differentiated instructional methods. In addition to the episodes, interview data with elementary school teachers also are presented as needed. This paper discusses two aspects of activating the curriculum into elementary mathematics classrooms. One deals with the issues of the curriculum and textbooks themselves, and the other covers those of research trends on mathematics education and teaching practices. This paper finally emphasizes a collaborative working relation among classroom teachers, mathematics educators, and policy makers with their own places and roles.