• Title/Summary/Keyword: epidemiological study

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Analysis of the Clinical and Histopathological Patterns of 100 Consecutive Cases of Primary Cutaneous Melanoma and Correlation with Staging

  • Nam, Kyung Wook;Bae, Yong Chan;Bae, Seong Hwan;Song, Kyung Ho;Kim, Hoon Soo;Choi, Young Jin
    • Archives of Plastic Surgery
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    • v.42 no.6
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    • pp.746-752
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    • 2015
  • Background This study analyzed 100 consecutive patients with primary cutaneous melanoma over the course of 13 years to determine whether epidemiological differences correspond to different stages of the disease. We also investigated whether epidemiological characteristics affected the survival rate. Our results were compared with those of selected descriptive studies of melanoma in other East Asian populations, in order to determine whether cutaneous melanoma patterns are similar in East Asian populations. Methods The patients' medical records were reviewed retrospectively, and we analyzed the relationship of epidemiological characteristics to staging and survival rate. Additionally, papers from Hong Kong and Japan describing these phenomena in East Asian populations were subjected to a statistical comparison. Results The ratio of males to females was 1:1.8, and the foot was the most frequent tumor site (49%). Acral lentiginous melanoma occurred most frequently (55%). Nodular melanoma was associated with a higher stage. Stage III-IV tumors with Clark levels of IV-V were significantly associated with a low survival rate. A statistical analysis of comparable papers reported in Hong Kong and Japan showed similar results with regard to age, tumor location, and histopathological subtypes. Conclusions This study provides the first full epidemiological description of 100 consecutive cases of primary cutaneous melanoma in Korea, with results similar to those observed in other East Asian populations. Corresponding to previous findings, nodular melanoma tended to occur at a higher stage than other types, and tumors with high Clark levels and high stages showed a lower survival rate.

Discrepancies Between Public Perceptions and Epidemiological Facts Regarding Cancer Survival Rate in Korea : An Online Survey (암 생존율에 대한 한국 대중의 인식과 역학적 사실 사이에서 발생하는 불일치 : 온라인 설문을 중심으로)

  • Kim, Jae-Woo;Kang, Jung-Kyu;Kim, Sung-Ho
    • The Journal of the Korea Contents Association
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    • v.17 no.1
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    • pp.113-119
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    • 2017
  • This study aims at investigating which factors affect the public perceptions of the survival rate of cancer. To this end, this study compares the public perception for 5-year survival rates of five major cancer(stomach, colorectal, liver, breast, uterine cervix) and actual epidemiological fact thereof. Data was collected from 19th to 24th April 2016 through online cross-sectional survey on 354 people. Frequency analysis was conducted to understand the characteristics of the subjects, histograms were presented for the comparison with the epidemiological fact, and multiple regression analysis was conducted. The subjects tended to aware the survival rates of stomach cancer, colorectal cancer, breast cancer, and uterine cervix cancer as lower than they epidemiologically represented. Finally, the factors that substantially affect the perception of 5-year survival rates were revealed as the experience of diagnosed as cancer, the age, and whether the subject regularly involved in a workout.

A Comparative Review of Radiation-induced Cancer Risk Models

  • Lee, Seunghee;Kim, Juyoul;Han, Seokjung
    • Journal of Radiation Protection and Research
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    • v.42 no.2
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    • pp.130-140
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    • 2017
  • Background: With the need for a domestic level 3 probabilistic safety assessment (PSA), it is essential to develop a Korea-specific code. Health effect assessments study radiation-induced impacts; in particular, long-term health effects are evaluated in terms of cancer risk. The objective of this study was to analyze the latest cancer risk models developed by foreign organizations and to compare the methodology of how they were developed. This paper also provides suggestions regarding the development of Korean cancer risk models. Materials and Methods: A review of cancer risk models was carried out targeting the latest models: the NUREG model (1993), the BEIR VII model (2006), the UNSCEAR model (2006), the ICRP 103 model (2007), and the U.S. EPA model (2011). The methodology of how each model was developed is explained, and the cancer sites, dose and dose rate effectiveness factor (DDREF) and mathematical models are also described in the sections presenting differences among the models. Results and Discussion: The NUREG model was developed by assuming that the risk was proportional to the risk coefficient and dose, while the BEIR VII, UNSCEAR, ICRP, and U.S. EPA models were derived from epidemiological data, principally from Japanese atomic bomb survivors. The risk coefficient does not consider individual characteristics, as the values were calculated in terms of population-averaged cancer risk per unit dose. However, the models derived by epidemiological data are a function of sex, exposure age, and attained age of the exposed individual. Moreover, the methodologies can be used to apply the latest epidemiological data. Therefore, methodologies using epidemiological data should be considered first for developing a Korean cancer risk model, and the cancer sites and DDREF should also be determined based on Korea-specific studies.

An Application Study of Accident Analysis Method Based on Epidemiological Model to Improve Occupational Safety and Health Management System (사업장 안전보건관리체계 향상을 위한 역학모형 기반의 사고분석기법 활용 방안 연구)

  • Kyunghwan Kim;Kihyo Jung
    • Journal of the Korea Safety Management & Science
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    • v.25 no.2
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    • pp.9-15
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    • 2023
  • The Severe Disaster Punishment Act had recently been established in order to promote safety and health (OSH) management system for severe accident prevention. OSH management system is primarily designed based on risk assessments; however, companies in industries have been experiencing difficulties in hazard identification and selecting proper measures for risk assessments and accident prevention. This study intended to introduce an accident analysis method based on epidemiological model in finding hazard and preventive measures. The accident analysis method employed in this study was proposed by the U.S. Department of Energy. To demonstrate the effectiveness of the accident analysis method, this study applied it to two accident cases occurred in construction and manufacturing industries. The application process and results of this study can be utilized in improving OSH management system and preventing severe accidents.

Epidemiological Study of Malaria Outbreak in the Northern-part of Kyonggi-do (경기북부지역의 말라리아에 관한 역학적 연구)

  • 박용배;홍해근;방선재;임준래;문혜경
    • Journal of environmental and Sanitary engineering
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    • v.15 no.1
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    • pp.46-53
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    • 2000
  • Korea has been free of malaria since the mid-1970s. Since the first malaria case was reported in 1993, the incidence of indigenous malaria has increased yearly, In this study, we planned to understand of malaria outbreak in the northern part of kyonggido. The subjects were a civilians except korean soldiers in the northern part of Kyonggido and the number of civilian malaria cases was 254 in 1997, 677 in 1998, 772 in 1999. The collected rates of Anopheles sinenis in 11 county from May to October were 10.1% to 85.1% and the monthly collected rates at June was highest. The incidence of malaria antibody according to the county was 5.4% in Paju-shi Tanhyun-myun 4.9% in Kapyong-gun Ha-myun, 3.0% in Yonchon-gun Yonchon-eup. etc. At the result of relationship between civilian cases and No. of A. sinenis, envionmental factor were showed high association.

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Development of Food Questionnaire for Korean Americans (재미 한인을 위한 식이섭취빈도 조사 설문지에 관한 연구)

  • 김정선
    • Journal of Nutrition and Health
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    • v.30 no.5
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    • pp.520-528
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    • 1997
  • This study was conducted to develop a food frequency questionnaire for an epidemiological study of dietary patterns and nutrient intake among Koeran American. A random sample of 101 Korean Americans between the ages of 17 and 71 residing in New York and New Jersey was interviewed by the method of 24-hour dietary recall. The foods Korean Americans consumed most frequently were rice (91% of the population), kimchee (81%), coffee(59%), bread(49%), apple(45%), bean sprouts (33%), milk (30%), dried anchovies (27%), eggs(27%), juice (26%), bulgogi, and soybean paste soup (24%, equally. The classification of food items standardized portion sizes were according to both Block's questionnaire and the standardized portion sizes by the Korean Nutrition Association. The value of this food frequency questionnaire is that it can accurately estimate dietary food patterns and nutrient intake among Korean Americans for epidemiological studies. It could also potentially be modified to study the relationship between specific diseases and food intake in the future.

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