• 대한한의학원전학회지
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• 제20권4호
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• pp.251-265
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• 2007

This study is a research on the etiology in Wu Youke's wenyi theory. In regard to the etiology of epidemic disease that had been spread on a very large scale at that time, Wu Youke denied the traditional theory which urged the irregular change of climate as the cause of epidemic disease, and proposed the concept of 'zaqi' which was considered by him to be something that could be the real cause of epidemic disease. And He treated the wenyi disease as something that has the same meaning with wenbing, so his concept on wenbing was basically the thing that treats 'zaqi' as the fundamental cause of wenbing and treats the concept of 'wen(溫)' as an environmental cause that could help activate the virulence of 'zaqi'. Such concept like this was the thing somewhat different from the traditional etiological theory that considers the change of climate as the principal cause of waigan(外感)-disease, and it must for the most part have been originated from the experience of Wu Youke himself. But this study, in contrast, based on the thing he denied the traditional theory on the irregular change of climate, has been done in the point of view that fundamental concept of his wenyi theory such as 'zaqi' was not only originated from his clinical experience but also from the influence of paradigm shift in the natural philosophy of that time. There had been so much change in cosmology and natural philosophy from the fundamental basis at that time, and the the most principal concept of it was that there always exists irregular faces in the change of nature. Such concept like this got into its stride from about 17th century, and it was expressed in the form of the severe criticism against the traditional natural philosophy. In regard to this, this study has outlined the academic thought of the leading scholars who made a significant progress in such a paradigm shift, and it includes the scholars like Wang Tingxiang, Wang Fuzhi, Hu Wei, Huang Zongxi, who played their role in the time of the latter period of Ming dynasty and the former period of Qing dynasty.

• Journal of Preventive Medicine and Public Health
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• 제38권4호
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• pp.420-424
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• 2005

Objectives : A few culture-confirmed cases of S. sonnei have been notified from Korean hospitals. The source of epidemic can't be firmly determined in such cases because of the rarity of this illness in the local communities and the timing of the outbreaks. The objective of this study is to estimate the source of epidemic by investigating the patients' lifestyles. Methods : Alibi verification was used to access the presumed source of the epidemic. PCR (Polymerase Chain Reaction) was used to rapidly detect the genes of Shigella in water specimens. Results : The common lifestyle trait among the Shigella infected patients was connected with Mt. Martyr in J city, Korea. The first patient's son had gone on a pilgrimage to Mt. Martyr with 41 friends and he had only eaten rice cakes on April 5th; the second patients had visited Mt. Martyr with their mother for a picnic on April 12th; the third patient had visited Mt. Martyr with 22 friends for a pilgrimage and the patient had only drunk holy water on April 13th. Therefore, the holy water of Mt. Martyr was reckoned to be the source of the epidemic. PCR detected the genes of Shigella two days before the S. sonnei was confirmed. Conclusion : The patients' lifestyles for 7 days before the onset of symptoms should be determined in terms of time, place and contacted people to find the source of infection when cases with food poisoning are seen in the hospital setting.

• 디지털융복합연구
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• 제16권7호
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• pp.259-265
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• 2018

수학모형의 한 유형인 구획모형은 전염병의 확산처럼 순차적인 이벤트나 프로세스로 구성된 동적 시스템의 변화를 분석하는 데 폭넓게 활용되어 왔다. 구획모형은 상자와 화살표로 표현되는 구획과 구획 간 관계로 구성된다. 이러한 원리는 stock과 flow로 구성되는 시스템다이내믹스(SD)의 모델링 원리와 비슷하다. 두 모형 모두 미분방정식을 이용하여 구조화된다. 이와 같은 두 모형 간 변환 가능성을 이용하여 국내 MERS 전염의 특징을 분석한 최근 연구의 SEIR 참조모형을 SD 관점에서 해석 변환한다. 변환된 SEIR 모형(Model 2)은 참조모형(Model 1)의 재현 결과와 비교하여 동일한 시뮬레이션 결과를 나타내었다. 본 연구는 전염병 구획모형의 구축에 도식과 미분방정식을 이용한 SD 방법론의 활용에 대한 인사이트를 제공하며, 변환된 SD 모형은 다른 전염병을 위한 참조모형으로 활용 가능하다.

• Journal of Preventive Medicine and Public Health
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• 제49권1호
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• pp.18-22
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• 2016

Ethical considerations are essential in planning for and responding to outbreaks of infectious diseases. During the outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in the Republic of Korea in 2015, serious challenges emerged regarding important ethical issues, such as transparency and the protection of privacy. The development of bioethics in Korea has been influenced by individualistic perspectives applied in clinical contexts, leading to a paucity of ethical perspectives relevant to population-level phenomena such as outbreaks. Alternative theories of public health ethics include the perspectives of relational autonomy and the patient as victim and vector. Public health actions need to incorporate clear and systematic procedures founded upon ethical principles. The MERS-CoV epidemic in Korea created significant public support for more aggressive early interventions in future outbreaks. This trend makes it all the more imperative for ethical principles and procedures to be implemented in future planning and responses to outbreaks in order to promote perceptions of legitimacy and civic participation.

• International Journal of Quality Innovation
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• 제4권1호
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• pp.46-53
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• 2003

Under the strong leadership of Chinese Government to the anti-SARS struggle, the situation has been successfully controlled. Since May 1 of 2003, the Ministry of Health of China published daily the number of newly increased SARS patient of Beijing, the authors analyzed these data using $X_cs$$-R_scs$ cause-selecting control charts of Statistical Diagnosis(SPD) Theory. Data about number of newly increased SARS patient consists of two kinds of variation: random variation and tendency variation of SARS epidemic. It is concluded that SARS epidemic of Beijing was already controlled since May 9 of 2003.

• 대한수학회보
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• 제49권3호
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• pp.517-528
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• 2012

This paper is estimating the domain of attraction for a class of susceptible-exposed-infectious-recovered (SEIR) epidemic dynamic models by using sum of squares optimization. First, the stability is analyzed for the equilibriums of SEIR model, and the domain of attraction in the endemic equilibrium is estimated by using sum of squares optimization. Finally, a numerical example is examined.

• 한국한의학연구원논문집
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• 제13권3호
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• pp.39-43
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• 2007

The history of medicine has a strong correlation to the ancient development of epidemics. Although the study of the history of East Asian Traditional Medicine does not put much emphasis in understanding the flow of medical history in relation to epidemics, it largely impacted the development of this epidemic and the compilation and evolution of treatment methods. The same was true for Korea as they linked development of epidemics, unusual natural conditions, and social phenomenons from ancient documents. This study methodically classifies the epidemics mentioned in ${\ulcorner}$三國史記${\lrcorner}$ and concludes on how ancient Koreans understood epidemics.

• 대한수의학회지
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• 제54권3호
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• pp.185-188
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• 2014

Porcine epidemic diarrhea virus (PEDV) strains responsible for recent outbreaks in the United States have been occurring in Mainland Korea since late 2013. Over the past 10 years, PEDV outbreaks have not been reported on Jeju Island. However, in late March of 2014, PEDV re-emerged on Jeju Island and was found to be genetically identical to PEDV strains currently circulating in Mainland Korea. The present study was conducted to provide a better understanding of the epidemiology of PEDV and more effective preventive measures against PED.

• 한국식물병리학회지
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• 제10권2호
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• pp.78-82
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• 1994

Unusually severe rice blast epidemic sweeped over the rice growing area in Gyeongnam Province and elsewhere in 1993. Leaf blast infection was reached to 33,133 ha, which is about 24.5% of total paddy area and neck blast infection was apparent throughout 4,421 ha. Major factors affecting such an unusual epidemic appeared to be as follow: Firstly, low temperature, frequent rainfall and coincidentally insufficient duration of sunshine through July and August; Secondly, most cultivars possessing low levels of field resistance were cultivated in wide areas: Thirdly, blast fungus population was enough for successive infection under optimum weather condition and most races distributed in field were able to infect most cultivars.

• 한국수의병리학회지
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• 제2권2호
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• pp.107-116
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• 1998

Twelve colostrum-deprived piglets were inoculated oral1y with porcine epidemic diarrhea virus isolated from Korea. The piglets were euthanatized from at 12 hour postinoculation(PI) at 6-hour intervals. At 24 to 36 hours PI, all infected piglets showed severe yellowish to watery diarrhea, dehydration, depression, and anorexia. At necropsy, the intestinal wall looked thin, mesenteric vessels congested, and mesenteric lymph nodes edematous. The histological findings showed marked villous atrophy and fusion, severe degeneration of enterocytes and monomuclear cell infiltration in the lamina propria. On electron microscopy, villous epithelial cells of infected jejunum contained viral particles at 18 hour PI. The viral particles were pleomorphic spheres with a mean diameter of 95∼180nm including 18nm projections.