• Membrane and Water Treatment
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• 제10권1호
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• pp.39-44
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• 2019

LID facilities do not consider environmental factors, and due to inappropriate vegetation planting causing degradation in efficiency due to plant damage and difficulty in maintenance. Therefore, in this study, assessment of impact environmental factor by seasonal variation of chlorophyll and growth of vegetation planted in LID technologies and change of pollutant reduction were conducted. In the case of B-SJ and B-RI, growth rate decreased after summer (August), and B-MG showed steady growth until autumn (September). Chlorophyll was found to increase during spring season while it decreased during autumn season. The chlorophyll concentration was found to affect the plant growth pattern. TN reduction efficiency was highest with greater than 80% efficiency in summer, and it was analyzed that plants were identified as the main factor affecting the seasonal reduction efficiency of TN. Also, temperature and relative humidity were analyzed to affect plant growth, activity and pollutant removal efficiency. Plant type and growth pattern are considered as factors to be considered in selection of appropriate plant types in LID technologies.

• 한국게임학회 논문지
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• 제22권1호
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• pp.99-108
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• 2022

신체 활동 증진을 위한 디지털 게임의 높은 활용에도 불구하고, 활동형 게임 이용에 영향을 미치는 요인에 대한 체계적 이해는 부족하다. 이 연구는 건강 행위의 생태학적 모형을 기반으로, 신체 활동에 영향을 미치는 요인을 개인적, 환경적, 사회적 요인으로 세분화하고, 신체 활동을 활동형 게임 이용과 일상적 신체 활동으로 구분하여 각 행위에 영향을 미치는 요인을 통합적으로 살펴보았다. 그 결과, 일상적 신체 활동은 세 요인이 모두 영향을 미치는 것과는 달리 활동형 게임 이용에는 사회적 요인만 영향을 미치는 것으로 나타났다. 이는 활동형 게임 이용 확대에 사회적 요인이 중요한 영향을 미칠 수 있음을 시사하고 있다.

• 한국환경보건학회지
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• 제30권3호
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• pp.230-238
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• 2004

The adverse health effects of a number of environment pollutions are related to the formation of free radicals. Induction of antioxidant defensive system in the response to an oxidative attack is an essential element of the cell to survive. CYP2E1 is easily induced by organic solvents and induces continuous formation of reactive oxygen species (ROS). ${\gamma}$-Glutamyltranspeptidase (${\gamma}$GT) plays an important role in glutathione metabolism and xenobiotic detoxification. To evaluate the characteristic of oxidative stress which induces GGT expression and to understand human antioxidant defensive response against oxidative stress induced by CYP2E1, we studied regulation of ${\gamma}$GT enzyme expression in response to various oxidative stresses in human HepG2 cells. The ${\gamma}$GT activity was not modified after exposure of acute oxidative stress inducing agents (ferric nitrilotriacetate, cumene hydroperoxide, ADP-Fe, O-tetradecanoylphorbol-13-acetate, tumor necrosis factor-alpha). To induce continuous exposure of cells to ROS, HepG2 cells were transfected by human CYP2E1 gene transiently. The CYP2E1 activity was verified with chlorzoxazone hydroxylation. Transfection of CYP2E1 showed continuous 60% increase in intracellular ROS and 240 % increase in microsomal ROS. CYP2E1 overexpressing cells showed increased ${\gamma}$GT activity (2.5-fold). The observed enhancement of ${\gamma}$GT activity correlated with a significant increase of ${\gamma}$GT mRNA (2.1-fold). Treatment with antioxidant strongly prevented the increase in ${\gamma}$GT activity. The CYP2E1 overexpression did not modify toxicity index and increased glutathione levels. These results show that continuous exposure of cells to ROS produced by CYP2E1 up-regulates ${\gamma}$GT; This may be one of the adaptive antioxidant responses of cells to oxidative insult. Present study also suggests that the induction of ${\gamma}$GT could be used as a marker of oxidative stress induced by exposure to organic solvents.

• KDI Journal of Economic Policy
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• 제24권1호
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• pp.113-190
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• 2002

The purpose of this paper is to perform empirical studies on the impact of pollution intensity on international competitiveness using 1993 and 1998 data, and to estimate the change in environmental regulation level faced by the firms during 1993~1998. Collecting relevant data and providing them for further studies in the area are another purposes of the paper. The first method is the regression of various indices of international competitiveness on factor costs, such as labor, capital, R&D and pollution abatement costs. Goal of the regression analysis is to estimate the scarcity and comparative advantage effect of each production factor, especially environmental resource. Regression results show that those industries which employ more environmental resource have higher comparative advantage in both years, which implies that Korean firms are endowed with abundant environmental resource compared to other countries. The second method is to compute the relative scarcity indices(HOVL indices) of production factors, proposed by Leamer based on Vanek's generalized Hecksher-Ohlin Theorem. This method estimates the relative scarcity of production factors by computing factor costs embodied in import and export of commodities. This method shows similar results as the regression method; i.e., trade pattern of production factors implies that the manufacturing sector in Korea is endowed with abundant environmental resource compared to other countries. Considering population density, water resource endowment, intensity of economic activity per unit area and current air and water pollution levels, it is evident that Korea is never endowed with abundant environmental resource compared to other countries. Then the abundance of environmental resource revealed by the trade patterns of commodities and production factors implies that Korea's environmental regulation level is excessively generous compared to environmental capacity, and that this increased the environmental resource endowment supplied to firms and thus distorted the inter-industry comparative advantages. Both regression and HOVL methods, on the other hand, show that overall environmental regulation level faced by the firms has been strengthened during 1993~1998.

• Mycobiology
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• 제43권3호
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• pp.319-326
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• 2015

Fomes fomentarius is a fungus of the Polyporaceae family and is used in traditional oriental therapies. Although the anti-inflammatory activities of this species have been previously reported, the identity of the bioactive compounds responsible for this activity remains unknown. Here, we investigated whether methyl 9-oxo-(10E,12E)-octadecadienoate (FF-8) purified from F. fomentarius exerts anti-inflammatory activity in murine macrophages stimulated with lipopolysaccharide (LPS). FF-8 suppressed secretion of nitric oxide (NO) and prostaglandin $E_2$ through downregulation of inducible NO synthase and cyclooxygenase-2 expression induced by LPS. In addition, pretreatment of cells with FF-8 led to a reduction in levels of secreted inflammatory cytokines such as tumor necrosis factor-${\alpha}$ and interleukin-6 in macrophages stimulated with LPS. Conversely, FF-8 did not affect nuclear factor ${\kappa}B$, p38, c-Jun NH2-terminal kinase, and extracellular signal-regulated kinase pathways. Instead, FF-8 specifically interfered with signal transducer and activator of transcription 3 (STAT3) phosphorylation induced by LPS. Collectively, this study demonstrated that FF-8 purified from F. fomentarius suppresses inflammatory responses in macrophages stimulated with LPS by inhibiting STAT3 activation. Further studies will be required to elucidate the anti-inflammatory effect of FF-8 in vivo.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.201-201
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• 2001

Transforming growth factor- $\beta$ (TGF- $\beta$), a hormonally active polypeptide found in normal and transformed tissue, is a potent regulator of cell growth and differentiation. In this study, we wished to establish an in vitro bioassay system to seek the most sensitive method that can measure TGF- $\beta$ activity.(omitted)

• 청정기술
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• 제29권2호
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• pp.151-159
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• 2023

탄소중립의 실현을 위해서는 다양한 이해관계자의 공동협력을 기반으로 거버넌스 제도를 활용하는 것이 합리적이다. 성공적인 거버넌스 운영은 구성원들이 어떤 활동 기준을 가지고 참여하는지가 중요하며, 특히 정책 집행 과정에서 과학적 조언을 할 수 있는 전문가에게는 성공적인 합의점 도출을 위한 가이드 공유가 필요하다. 본 연구에서는 거버넌스 참여 과학기술전문가의 활동기준 제시를 위한 공통성공요인을 도출하고자 거버넌스 모형이론과 모형구조, 사례별 공통성공요인, 서울시 기후환경분야 거버넌스 사례적용 등의 조사 분석을 수행하였다. 모형이론 연구결과, 모형구조는 공통적으로 '조건-과정-결과'의 구조로 되어 있으며 구성원들의 활동시기인 '과정' 단계에서 공통성공요인을 도출할 수 있음을 확인하였다. 공통성공요인의 사례조사를 통해 중복요인은 신뢰성, 책임성, 투명성 및 네트워크로 도출되었다. 공통성공요인의 타당성을 검증하기 위해 서울시 거버넌스의 참여자 만족도 조사자료를 활용하여 분석한 결과, 결과값은 신뢰성 > 네트워크 > 투명성 > 책임성의 순으로 확인되었으며, 관련 요인들이 적절하게 도출됨을 알 수 있었다. 본 연구결과가 향후 과학기술분야 전문가의 활동요인으로 활용되어 탄소중립 정책의 수용성과 효용성을 높일 수 있기를 기대한다.

• 한국대기환경학회지
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• 제27권4호
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• pp.405-415
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• 2011

The objective of this study was to compare greenhouse gas emissions from road transportation by calculation methods (Tier 1, Teir 2, and Tier 3). Tier 1 based on 2006 IPCC guidelines default emission factor and amount of fuel consumption. The Tier 2 approach is the same as Tier 1 except that country-specific carbon contents of the fuel sold in road transport are used. Tier 2 based on emission factor of guidelines for local government greenhouse gas inventories (Korea Environment Corporation), the fuel consumption per one vehicle, and the registered motor vehicles. The Tier 3 approach requires detailed, country-specific data to generate activity-based emission factors for vehicle subcategories (National Institute of Environmental Research) and may involve national models. Tier 3 calculates emissions by multiplying emission factors by vehicle activity levels (e.g., VKT) for each vehicle subcategory and possible road type. VKT was estimated by using GIS road map and traffic volume of the section. The GHG average emission rate by the Tier 1 was 728,857 $tonCO_2eq$/yr, while Tier 2 and Tier 3 were 864,757 $tonCO_2eq$/yr and 661,710 $tonCO_2eq$/yr, respectively. Tier 3 was underestimated by 10.1 and 20.7 percent for the GHG emission observed by Tier 1 and Tier 2, respectively. Based on this study, we conclude that Tier 2 is reasonable GHG emissions than Tier 1 or Tier 3. But, further study is still needed to accurate GHG emission from Tier 3 method by expanding the traffic survey area and developing the model of local road traffic.

• 한국대기환경학회지
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• 제30권1호
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• pp.48-58
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• 2014

It is very important to investigate air pollutants emissions emitted from open burning in order to control nonpoint sources effectively. In this study, we utilized incineration simulator proposed by U.S EPA and investigated emissions of CO, OC/EC, from household waste and biomass burning to estimate pollutant emissions by illegal incineration of biomass wastes. Emission factor of OC was estimated as 17.1 g/kg for rice strew, 23.5 g/kg for barley, 10.3 g/kg for corn stover, 4.3 g/kg for unseasoned wood, respectively. In case of EC, it was calculated as 1.6 g/kg for rice strew, 4.3 g/kg for barley, 1.4 g/kg for corn stover, 0.6 g/kg for unseasoned wood, respectively. Most of the pollutants emissions were emitted at the stage 1 and 2. In the stage 3, the pollutants concentration decreased gradually. To estimate emissions and build inventory for biomass burning, we need to know accurate activity data. We, therefore, used activity data of both survey results of previous study and statistical data of National Statistical Office. However, we need to perform additional experiments in the future to obtain more accurate activity data for various cases.

• Journal of Applied Biological Chemistry
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• 제50권3호
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• pp.109-114
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• 2007

Sar1p is a ras-related GTP-binding protein that functions in intracellular protein transport between the endoplasmic reticulum (ER) and the Golgi complex. The effector domain of Ras family proteins is highly conserved and this domain is functionally interchangeable in plant, yeast and mammalian Sar1. Using a recombinant Brassica sar1 protein (Bsar1p) harboring point mutations in its effector domain, we here investigated the ability of Sar1p to bind and hydrolyze GTP and to interact with the two sar1-specific regulators, GTPase activating protein (GAP) and guanine exchange factor (GEF). The T51A and T55A mutations impaired Bsar1p intrinsic GTP-binding and GDP-dissociation activity. In contrast, mutations in the switch domain of Bsar1 did not affect its intrinsic GTPase activity. Moreover, the P50A, P54A, and S56A mutations affected the interaction between Bsar1p and GAP. P54A mutant protein did not interact with two regulating proteins, GEF and GAP, even though the mutation didn't affect the intrinsic GTP-binding, nucleotide exchange or GTPase activity of Bsar1p.