• 대한간호학회지
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• 제30권4호
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• pp.857-868
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• 2000

The purpose of the present study is to identify the mediation effect of hope between fatigue and psychosocial adjustment in women with breast cancer. The framework for this study was guided by concepts and propositions derived from the theoretical and empirical literature on fatigue, hope and adjustment. The design of this study is a descriptive correlation study using a cross-sectional design. One hundred and twenty two outpatients with early breast cancer, receiving post-surgical radiation therapy or chemotherapy, were selected from three major medical centers in Seoul, Korea. A packet including PABCF (Psychosoical Adjustment to Breast Cancer Factor), revised RPFS (Revised Piper Fatigue Scale), HHI (Herth Hope Index), and self-addressed return envelope was given to the participants at seven to eight weeks post surgery. The questionnaires were to be completed at home and returned to the researcher by mail. The obtained data were analyzed using three regression equations guided by Baron and Kenny (1986); first, hope was regressed on fatigue; second, psychosocial adjustment was regressed on fatigue; and third, psychosocial adjustment was regressed on fatigue and hope, simultaneously. In the first equation, fatigue explained 4% of the variance in hope. In the second equation, fatigue explained 47% of the variance in psychosocial adjustment. In the last equation, hope and fatigue significantly explained the variance in psychosocial adjustment. Therefore, all conditions for the test of mediation effect of hope were satisfied. For the test of the mediation effect, the beta coefficients of fatigue on psychosocial adjustment on the second and third regression equations were compared. The beta coefficients were decreased from .69 (p < .001) on the second regression equation to .63 (p < .001) on the third regression equation. Thus, the hypothesis of this study was supported. As a result of this study, the negative Influence of fatigue on psychosocial adjustment is dampened through the mediator effect of hope in women with breast cancer. Therefore, when planning care for the adverse effect of fatigue on psychosocial adjustment, oncology nurses should consider hope as a mediator between fatigue and psychosocial adjustment to breast cancer.

• 한국통신학회논문지
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• 제38A권1호
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• pp.79-87
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• 2013

전력 및 대역폭 제한적 디지털통신 시스템을 위한 새로운 변조 기술인 상관부호화 FSK (CEFSK) 시스템의 성능을 단일 및 다중 반송파 비선형 채널 환경에서 분석하였다. CEFSK는 심볼간 간섭이 없으며 인접하는 두 심볼간의 진폭과 위상 사이에 상관관계를 유지함으로써 부드럽고 연속적인 위상천이와 함께 적은 포락선 변동을 갖는 출력신호를 생성한다. 따라서 CEFSK 시스템은 기존의 GFSK와 비교하여 비선형 왜곡에 대한 인접심볼간섭(ISI)과 혼변조(IM)에 의한 영향을 적게 받는다. 본 논문에서는 AWGN과 ISI 그리고 IM 성분을 갖는 비선형 증폭 채널 환경에서 CEFSK 시스템의 성능을 전산모의실험을 통해서 분석하였다. 단일채널에 대한 실험에서는 고출력증폭기의 입력 차단 (IBO)가 -1.0dB와 -3.0dB일 때, 단일 비트 차동검파 (1DD) CEFSK가 $BER=1{\times}10^{-4}$을 유지하기 위해서 1DD-GFSK 보다 1.2dB와 0.8dB 우수하고 다중채널의 경우에서는 IBO의 값과 무관하게 약 1.1dB 우수하였다.

• 대한토목학회논문집
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• 제13권4호
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• pp.65-75
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• 1993

본 연구는 규모가 큰 지진하중에 대한 해양 가이드 타워의 비정상과정 거동해법에 주안점을 두었으며, 아울러 작은 파랑이나 조류하중이 동시에 작용할 수 있는 경우도 고려하였다. 지진에 의한 지반운동의 비정상특성은 정상과정 성분에 지수함수의 시간포락함수를 곱하는 형태로 모형화하였다. 동적거동의 비정상과정 분산값을 해석적인 방법으로 산출하였다. 운동방정식에 계류장치의 비선형 복원력과 파동에 의한 비선형 점성저항력을 추계론적 최적화기법으로 선형화하여 동적해석을 수행하였다. 지진의 발생기간동안 예상되는 중급의 파랑하중에 의한 영향을 최대거동 산정시 고려하였다. 중급 파고조건에 대한 파랑하중은 지속기간이 상당히 길어서 정상과정으로 취급할 수 있으므로 이에 대해서는 주파수 영역해석을 사용하여 동적거동을 산출하고 이 결과를 지진에 의한 비정상과정거동에 반영하였다. 예제해석으로부터 비정상과정 해석방법을 검증하고, 지진과 파랑 및 조류하중의 각 성분이 전체응답에 미치는 영향을 분석하였다.

• 비파괴검사학회지
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• 제33권2호
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• pp.205-211
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• 2013

초음파 감쇠를 이용하여 티타늄 용접부에 대해 기계적 특성, 파단면 및 초음파특성을 연구하였다. 준비된 티타늄 시험편은 아르곤 가스를 이용하여 제작하였다. 티타늄 용접 시험편이 파단 되었을 때 변화하는 초음파 신호변화를 확인하기 위해서 인장시험을 실시하였다. 주사전자현미경을 이용하여 파단면을 관찰하고, 4 MHz 수직 탐촉자를 이용하여 초음파 시계열 신호를 획득하였다. 티타늄 판재에서 용접부는 모재부와 열영향부에 비하여 기계적 특성이 떨어지며 파단면분석을 통해 용접부의 입자크기가 모재부보다 큼을 확인할 수 있었다. RMS 신호 처리한 초음파 포락선의 면적과 인장강도의 상관관계를 나타내었다. 따라서 초음파를 이용하여 티타늄 용접부의 건전성 평가 방법이 유용함을 알 수 있었다.

• Clinical and Experimental Pediatrics
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• 제61권3호
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• pp.78-83
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• 2018

Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables. Methods: Nineteen preterm infants with feeding desaturation (group 1) and 19 age-matched full-term infants (group 2) were evaluated. Oromotor function was evaluated using video recording. The root-mean-square (RMS) envelope of the electromyography signal was calculated to quantify the activities of muscles involved in respiration. The differences in RMS between both groups and the correlation with clinical variables including gestational age (GA), birth weight (BW), and Apgar scores (AS) at 1 and 5 minutes after birth were evaluated. Results: The RMS values of the diaphragm (RMS-D) and rectus abdominis (RMS-R) were significantly greater in group 1 compared to group 2, and the 1- and 5-min AS were significantly lower in group 1 compared to group 2. RMS-D and RMS-R were inversely correlated with GA, BW, 1- and 5-min AS in all infants. Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.

• 한국통신학회논문지
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• 제28권7C호
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• pp.678-687
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• 2003

전력 및 대역폭 제한적인 디지털 통신 시스템을 위한 새로운 변복조 기술인 8SQAM(8-state Superposed Quadrature Amplitude Modulation)은 인접하는 두 심볼간에 진폭과 위상이 상관관계를 유지함으로써 부드럽고 연속적인 위상천이와 함께 적은 포락선 변동을 갖는 출력신호를 생성한다. 또한 8SQAM신호는 심볼간 간섭이 없으며 compact한 스펙트럼 특성을 갖는다. 따라서 8SQAM은 기존의 8PSK와 비교하여 비선형 왜곡에 의한 혼변조(IM)와 인접 심볼 간섭(ISI) 그리고 다중채널(SCPC-FDMA) 환경에서의 인접 채널 간섭(ACI) 영향을 적게 받는다. 본 논문에서는 비선형 증폭 다중채널 간섭 환경에서 8SQAM 시스템의 수신 성능을 전산모의 실험을 통해서 분석하였다. 전산모의 실험 결과 8SQAM은 고출력증폭기(HPA)의 Input back-off(IBO)가 1dB이고 채널 간격이 데이터 비트 율의 41.7%(즉, 스펙트럼 효율 =2.40b/s/Hz)일 때, BER=1$\times$$10^{-4}$ 을 유지하기 위해 요구되는 CNR이 $\alpha$= 0.3의 roll-off 값을 갖는 8PSK 보다 2.7dB 우수한 성능을 보였다.

• 한국통신학회논문지
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• 제28권7C호
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• pp.669-677
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• 2003

전력 및 대역폭 제한적인 디지털 통신 시스템을 위한 새로운 변복조 기술인 8SQAM(8-state Superposed Quadrature Amplitude Modulation) 시스템을 제안한다. 8SQAM은 심볼간 간섭(ISI)이 없으며 인접하는 두 심볼간의 진폭과 위상 사이에 상관관계를 유지함으로써 부드럽고 연속적인 위상천이와 함께 적은 포락선 변동을 갖는 출력신호를 생성한다. 따라서 8SQAM 시스템은 기존의 8PSK와 비교하여 비선형 왜곡에 의한 ISI와 혼변조(IM)에 의한 영향을 적게 받는다. 본 논문에서는 백색 가우시안 잡음 (AWGN)과 ISI 그리고 IM 성분을 갖는 비선형 증폭 채널 환경에서 8SQAM 시스템의 성능을 전산모의 실험을 통해서 분석하였다. 전산모의 실험결과 8SQAM은 고출력증폭기(HPA)의 input back-off(IBO)가 3dB일 때, BER=1$\times$$10^{-4}$ 을 유지하기 위해서 요구되는 CNR 값이 $\alpha$ = 0.25의 roll-off 값을 갖는 8PSK 보다 2.5dB 우수한 성능을 갖는다.

• 천문학회보
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• 제39권1호
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• pp.63.2-63.2
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• 2014

As a part of the "Dust, Ice, and Gas In Time" (DIGIT) key program on Herschel, we observed GSS30-IRS1, a Class I protostar located in Ophiuchus (d =125 pc), with Herschel/Photodetector Array Camera and Spectrometer (PACS). More than 70 lines were detected within a wavelength range from 50 ${\mu}m$ to 200 ${\mu}m$: CO lines from J = 14-13 to 41-40, several $H_2O$ lines of Eup = 100 K to 1500 K, 16 transitions of OH rotational lines, and two atomic [O I] lines at 63 and 145 ${\mu}m$. The [C II] line, known as a tracer of externally heated gas by the interstellar radiation field, is also detected at 158 ${\mu}m$. All lines, except [O I] and [C II], are detected only at the central spaxel of $9^{\prime\prime}.4{\times}9^{\prime\prime}.4$. The [O I] emission is extended along a NE-SW orientation, which is consistent with the known outflow direction, while the [C II] line is detected over all spaxels. One possible explanation of the detection of the [C II] line and no correlation of its spatial distribution with any other molecular emission is the existence of the enhanced ISRF nearby GSS30-IRS1. One interesting feature of GSS30-IRS1 is that the continuum emission is extended beyond the point-spread function (PSF), unlike the molecular line emission, indicative of significant external heating. The best-fit continuum model of GSS30-IRS1 with the physical structure including flared disk, envelope, and outflow shows that the internal luminosity is 11 $L_{\odot}$, and the region is also externally heated by a radiation field enhanced by a factor of 25 compared to the local standard interstellar field.

• BMB Reports
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• 제54권7호
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• pp.368-373
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• 2021

The vertebrate genome contains an endogenous retrovirus that has been inherited from the past millions of years. Although approximately 8% of human chromosomal DNA consists of sequences derived from human endogenous retrovirus (HERV) fragments, most of the HERVs are currently inactive and noninfectious due to recombination, deletions, and mutations after insertion into the host genome. Several studies suggested that Human endogenous retroviruses (HERVs) factors are significantly related to certain cancers. However, only limited studies have been conducted to analyze the expression of HERV derived elements at protein levels in certain cancers. Herein, we analyzed the expression profiles of HERV-K envelope (Env) and HERV-R Env proteins in eleven different kinds of cancer tissues. Furthermore, the expression patterns of both protein and correlation with various clinical data in each tissue were analyzed. The expressions of both HERV-K Env and HERV-R Env protein were identified to be significantly high in most of the tumors compared with normal surrounding tissues. Correlations between HERV Env expressions and clinical investigations varied depending on the HERV types and cancers. Overall expression patterns of HERV-K Env and HERV-R Env proteins were different in every individual but a similar pattern of expressions was observed in the same individual. These results demonstrate the expression profiles of HERV-K and HERV-R Env proteins in various cancer tissues and provide a good reference for the association of endogenous retroviral Env proteins in the progression of various cancers. Furthermore, the results elucidate the relationship between HERV-Env expression and the clinical significance of certain cancers.

• Earthquakes and Structures
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• 제16권5호
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• pp.563-573
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• 2019

When generating spectrum-compatible artificial ground motion in engineering practices, the effect of the variation in fitting parameters on the distribution of the peak ground displacement (PGD) has not yet drawn enough attention. In this study, a method for simulating ground motion matching for multiple targets is developed. In this method, a frequency-dependent amplitude envelope function with statistical parameters is introduced to simulate the nonstationarity of the frequency in earthquake ground motion. Then, several groups of time-history acceleration with different temporal and spectral nonstationarities were generated to analyze the effect of nonstationary parameter variations on the distribution of PGD. The following conclusions are drawn from the results: (1) In the simulation of spectrum-compatible artificial ground motion, if the acceleration time-history is generated with random initial phases, the corresponding PGD distribution is quite discrete and an uncertain number of PGD values lower than the limit value are observed. Nevertheless, the mean values of PGD always meet the requirement in every group. (2) If the nonstationary frequencies of the ground motion are taken into account when fitting the target spectrum, the corresponding PGD values will increase. A correlation analysis shows that the change in the mean and the dispersion values, from before the frequencies are controlled to after, correlates with the modal parameters of the predominant frequencies. (3) Extending the maximum period of the target spectrum will increase the corresponding PGD value and, simultaneously, decrease the PGD dispersion. Finally, in order to control the PGD effectively, the ground motion simulation method suggested in this study was revised to target a specified PGD. This novel method can generate ground motion that satisfies not only the required precision of the target spectrum, peak ground acceleration (PGA), and nonstationarity characteristics of the ground motion but also meets the required limit of the PGD, improving engineering practices.