• Title/Summary/Keyword: entrapment

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Enzymatic Properties of Atrazine Chlorohydrolase Entrapped in Biomimetic Silica

  • Ho, Cuong Tu;Kang, Su-Il;Hur, Hor-Gil
    • Journal of Applied Biological Chemistry
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    • v.51 no.4
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    • pp.143-147
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    • 2008
  • Purified atrazine chlorohydrolase (AtzA) was entrapped in the nanoparticles of biomimetically synthesized silica at the ambient condition within 20 min. Entrapped AtzA in biomimetic silica was less affected by pH change and showed higher thermostability than free enzymes. The entrapped AtzA was also more tolerant against proteolysis, with 80% of the initial activity remaining and retained 82% of the initial activity even after four cycles of usage. These results suggest that entrapment of AtzA in biomimetic silica could be utilized under diverse environmental conditions with the active catalytic performance sustained.

Management of Meralgia Paresthetica by Lateral Femoral Cutaneous Nerve Block -Case reports- (대퇴신경지각이상증의 치료를 위한 외측대퇴피신경차단 -증례보고-)

  • Lee, Hyo-Keun;Chung, So-Young;Lee, Seong-Yeon;Suh, Young-Sun;Kim, Chan
    • The Korean Journal of Pain
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    • v.8 no.1
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    • pp.152-155
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    • 1995
  • Meralgia paresthetica is a disorder characterized by a pain or dysaesthesia, or both, in the anterolateral aspect of the thigh caused by entrapment or neurinoma formation of the lateral femoral cutaneous nerve. Currently available modes of therapy include conservative treatment, lateral femoral cutaneous nerve block with steroids and local anesthetics, and surgery. At our neuro-pain clinic, w recently encountered three cases of meralgia paresthetica, all of which were treated by lateral femoral cutaneous nerve block. In which of them, two cases were successfully treated but one case was associate with pain relapse due to entrapment of lateral femoral cutaneous nerve by a retroperitoneal mass, schwannoma. In this paper we report our experience along with a review of the current literatures.

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Estimating the Viability of Bifidobacterium longum in Ca-Alginate Beads Against Simulated Gastroenteric Juices

  • Lee, Ki-Yong;Kim, Ji-Youn;Lee, Yoon-Jong;Choi, Eon-Ho;Shin, Dong-Hoon;Heo, Tae-Ryeon
    • Journal of Microbiology and Biotechnology
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    • v.11 no.1
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    • pp.97-105
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    • 2001
  • The viability of Bifidobacterium longum KCTC 3128, entrapped in calcium alginate beds in simulated gastroenteric juices (gastric and bile salt solution), was tested to evaluate the influences of several parameters (gel concentration, bead size, and initial cell number). The death rate of B. longum in beads after being sequentially exposed to simulated gastric juices and bile salt solution decreased propertionally with increasing both the alginate gel concentration and bead size. The number of initial cell loading in beads affected the numbers of survivors after being exposed to these solutions, while the death rate of the viable cells were not affected. From the results obtained, the influence of entrapment parameters on the survival of bifidobacteria was quantitatively and systematically evaluated by using a mathematical method.

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Solid Lipid Microspheres for Controlled Release Abdominal Injection of Local Anesthetic (고형지질마이크로스피어를 이용한 방출제어형 국소마취주사제의 제제설계 및 평가)

  • 박용근;이종화;김동우;윤재남;전일순;이은미;이계원;지웅길
    • YAKHAK HOEJI
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    • v.47 no.2
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    • pp.78-84
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    • 2003
  • Local anesthetics are used to reduce pain, but they are so frequently injected to patients. So, we prepared lidocaine solid lipid microspheres (SLM) as long acting abdominal injection using spray drying method and evaluated drug entrapment, particle size, SEM, zeta potential and in vitro and in vivo drug release pattern, The particle sizes of SLM were 30∼100$\mu$m and it is enough to inject into abdominal tissue. The entrapment efficiency of SLM was over 95% as spray drying method. Surfactant and PC decreased the burst effect by 20∼30%. In in vivo test, C-6 showed controlled release concentration profile in plasma for 8 days and C-5 sustained longer than we expected.

Fabrication of Nano-sized Titanate Powder via a Polymeric Steric Entrapment Route and Planetary Milling Process

  • Lee, Sang-Jin;Lee, Chung-Hyo
    • Journal of the Korean Ceramic Society
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    • v.39 no.4
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    • pp.336-340
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    • 2002
  • Pure and nano-sized $TiO_2$ and $CaTiO_3$ powders were fabricated by a polymeric steric entrapment route and planetary milling process. An ethylene glycol was used as a polymeric carrier for the preparation of organic-inorganic precursors. Titanium isopropoxide and calcium nitrate were dissolved in liquid-type ethylene glycol without any precipitation. At the optimum amount of the polymer, the metal cations were dispersed in solution and a homogeneous polymeric network was formed. The dried precursor ceramic gels were turned to porous powders through calcination process. The porous powders were crystallized at low temperatures and the crystalline powders were planetary milled to nano size.

Sural Nerve Entrapment and Tenosynovitis of Peroneus Longus by Hypertrophied Peroneal Tubercle: A Case Report (비후된 비골 결절에 의해 발생한 비복신경 포착 및 장비골건의 건막염: 증례 보고)

  • Lee, Dong Joo;Choi, Jun Young;Suh, Jin Soo
    • Journal of Korean Foot and Ankle Society
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    • v.22 no.3
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    • pp.131-134
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    • 2018
  • A hypertrophied peroneal tubercle can present as a bony prominence at the lateral aspect of the foot and a peroneal tenosynovitis or tear. We report a case of a 52-year-old man complaining of lateral foot tingling pain and numbness. The sural nerve entrapment and peroneus longus tenosynovitis by hypertrophied peroneal tubercle were confirmed. Good results were obtained after excision of the hypertrophied peroneal tubercle and sural nerve release.