• Title/Summary/Keyword: ensemble vector

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Development of Classification Model for hERG Ion Channel Inhibitors Using SVM Method (SVM 방법을 이용한 hERG 이온 채널 저해제 예측모델 개발)

  • Gang, Sin-Moon;Kim, Han-Jo;Oh, Won-Seok;Kim, Sun-Young;No, Kyoung-Tai;Nam, Ky-Youb
    • Journal of the Korean Chemical Society
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    • v.53 no.6
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    • pp.653-662
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    • 2009
  • Developing effective tools for predicting absorption, distribution, metabolism, excretion properties and toxicity (ADME/T) of new chemical entities in the early stage of drug design is one of the most important tasks in drug discovery and development today. As one of these attempts, support vector machines (SVM) has recently been exploited for the prediction of ADME/T related properties. However, two problems in SVM modeling, i.e. feature selection and parameters setting, are still far from solved. The two problems have been shown to be crucial to the efficiency and accuracy of SVM classification. In particular, the feature selection and optimal SVM parameters setting influence each other, which indicates that they should be dealt with simultaneously. In this account, we present an integrated practical solution, in which genetic-based algorithm (GA) is used for feature selection and grid search (GS) method for parameters optimization. hERG ion-channel inhibitor classification models of ADME/T related properties has been built for assessing and testing the proposed GA-GS-SVM. We generated 6 different models that are 3 different single models and 3 different ensemble models using training set - 1891 compounds and validated with external test set - 175 compounds. We compared single model with ensemble model to solve data imbalance problems. It was able to improve accuracy of prediction to use ensemble model.

Sensor Fault Detection Scheme based on Deep Learning and Support Vector Machine (딥 러닝 및 서포트 벡터 머신기반 센서 고장 검출 기법)

  • Yang, Jae-Wan;Lee, Young-Doo;Koo, In-Soo
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.18 no.2
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    • pp.185-195
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    • 2018
  • As machines have been automated in the field of industries in recent years, it is a paramount importance to manage and maintain the automation machines. When a fault occurs in sensors attached to the machine, the machine may malfunction and further, a huge damage will be caused in the process line. To prevent the situation, the fault of sensors should be monitored, diagnosed and classified in a proper way. In the paper, we propose a sensor fault detection scheme based on SVM and CNN to detect and classify typical sensor errors such as erratic, drift, hard-over, spike, and stuck faults. Time-domain statistical features are utilized for the learning and testing in the proposed scheme, and the genetic algorithm is utilized to select the subset of optimal features. To classify multiple sensor faults, a multi-layer SVM is utilized, and ensemble technique is used for CNN. As a result, the SVM that utilizes a subset of features selected by the genetic algorithm provides better performance than the SVM that utilizes all the features. However, the performance of CNN is superior to that of the SVM.

A Study on Comparison of Lung Cancer Prediction Using Ensemble Machine Learning

  • NAM, Yu-Jin;SHIN, Won-Ji
    • Korean Journal of Artificial Intelligence
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    • v.7 no.2
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    • pp.19-24
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    • 2019
  • Lung cancer is a chronic disease which ranks fourth in cancer incidence with 11 percent of the total cancer incidence in Korea. To deal with such issues, there is an active study on the usefulness and utilization of the Clinical Decision Support System (CDSS) which utilizes machine learning. Thus, this study reviews existing studies on artificial intelligence technology that can be used in determining the lung cancer, and conducted a study on the applicability of machine learning in determination of the lung cancer by comparison and analysis using Azure ML provided by Microsoft. The results of this study show different predictions yielded by three algorithms: Support Vector Machine (SVM), Two-Class Support Decision Jungle and Multiclass Decision Jungle. This study has its limitations in the size of the Big data used in Machine Learning. Although the data provided by Kaggle is the most suitable one for this study, it is assumed that there is a limit in learning the data fully due to the lack of absolute figures. Therefore, it is claimed that if the agency's cooperation in the subsequent research is used to compare and analyze various kinds of algorithms other than those used in this study, a more accurate screening machine for lung cancer could be created.

Investigation of Analysis Effects of ASCAT Data Assimilation within KIAPS-LETKF System (앙상블 자료동화 시스템에서 ASCAT 해상풍 자료동화가 분석장에 미치는 효과 분석)

  • Jo, Youngsoon;Lim, Sujeong;Kwon, In-Hyuk;Han, Hyun-Jun
    • Atmosphere
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    • v.28 no.3
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    • pp.263-272
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    • 2018
  • The high-resolution ocean surface wind vector produced by scatterometer was assimilated within the Local Ensemble Transform Kalman Filter (LETKF) in Korea Institute of Atmospheric Prediction Systems (KIAPS). The Advanced Scatterometer (ASCAT) on Metop-A/B wind data was processed in the KIAPS Package for Observation Processing (KPOP), and a module capable of processing surface wind observation was implemented in the LETKF system. The LETKF data assimilation cycle for evaluating the performance improvement due to ASCAT observation was carried out for approximately 20 days from June through July 2017 when Typhoon Nepartak was present. As a result, we have found that the performance of ASCAT wind vector has a clear and beneficial effect on the data assimilation cycle. It has reduced analysis errors of wind, temperature, and humidity, as well as analysis errors of lower troposphere wind. Furthermore, by the assimilation of the ASCAT wind observation, the initial condition of the model described the typhoon structure more accurately and improved the typhoon track prediction skill. Therefore, we can expect the analysis field of LETKF will be improved if the Scatterometer wind observation is added.

Ensemble Learning with Support Vector Machines for Bond Rating (회사채 신용등급 예측을 위한 SVM 앙상블학습)

  • Kim, Myoung-Jong
    • Journal of Intelligence and Information Systems
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    • v.18 no.2
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    • pp.29-45
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    • 2012
  • Bond rating is regarded as an important event for measuring financial risk of companies and for determining the investment returns of investors. As a result, it has been a popular research topic for researchers to predict companies' credit ratings by applying statistical and machine learning techniques. The statistical techniques, including multiple regression, multiple discriminant analysis (MDA), logistic models (LOGIT), and probit analysis, have been traditionally used in bond rating. However, one major drawback is that it should be based on strict assumptions. Such strict assumptions include linearity, normality, independence among predictor variables and pre-existing functional forms relating the criterion variablesand the predictor variables. Those strict assumptions of traditional statistics have limited their application to the real world. Machine learning techniques also used in bond rating prediction models include decision trees (DT), neural networks (NN), and Support Vector Machine (SVM). Especially, SVM is recognized as a new and promising classification and regression analysis method. SVM learns a separating hyperplane that can maximize the margin between two categories. SVM is simple enough to be analyzed mathematical, and leads to high performance in practical applications. SVM implements the structuralrisk minimization principle and searches to minimize an upper bound of the generalization error. In addition, the solution of SVM may be a global optimum and thus, overfitting is unlikely to occur with SVM. In addition, SVM does not require too many data sample for training since it builds prediction models by only using some representative sample near the boundaries called support vectors. A number of experimental researches have indicated that SVM has been successfully applied in a variety of pattern recognition fields. However, there are three major drawbacks that can be potential causes for degrading SVM's performance. First, SVM is originally proposed for solving binary-class classification problems. Methods for combining SVMs for multi-class classification such as One-Against-One, One-Against-All have been proposed, but they do not improve the performance in multi-class classification problem as much as SVM for binary-class classification. Second, approximation algorithms (e.g. decomposition methods, sequential minimal optimization algorithm) could be used for effective multi-class computation to reduce computation time, but it could deteriorate classification performance. Third, the difficulty in multi-class prediction problems is in data imbalance problem that can occur when the number of instances in one class greatly outnumbers the number of instances in the other class. Such data sets often cause a default classifier to be built due to skewed boundary and thus the reduction in the classification accuracy of such a classifier. SVM ensemble learning is one of machine learning methods to cope with the above drawbacks. Ensemble learning is a method for improving the performance of classification and prediction algorithms. AdaBoost is one of the widely used ensemble learning techniques. It constructs a composite classifier by sequentially training classifiers while increasing weight on the misclassified observations through iterations. The observations that are incorrectly predicted by previous classifiers are chosen more often than examples that are correctly predicted. Thus Boosting attempts to produce new classifiers that are better able to predict examples for which the current ensemble's performance is poor. In this way, it can reinforce the training of the misclassified observations of the minority class. This paper proposes a multiclass Geometric Mean-based Boosting (MGM-Boost) to resolve multiclass prediction problem. Since MGM-Boost introduces the notion of geometric mean into AdaBoost, it can perform learning process considering the geometric mean-based accuracy and errors of multiclass. This study applies MGM-Boost to the real-world bond rating case for Korean companies to examine the feasibility of MGM-Boost. 10-fold cross validations for threetimes with different random seeds are performed in order to ensure that the comparison among three different classifiers does not happen by chance. For each of 10-fold cross validation, the entire data set is first partitioned into tenequal-sized sets, and then each set is in turn used as the test set while the classifier trains on the other nine sets. That is, cross-validated folds have been tested independently of each algorithm. Through these steps, we have obtained the results for classifiers on each of the 30 experiments. In the comparison of arithmetic mean-based prediction accuracy between individual classifiers, MGM-Boost (52.95%) shows higher prediction accuracy than both AdaBoost (51.69%) and SVM (49.47%). MGM-Boost (28.12%) also shows the higher prediction accuracy than AdaBoost (24.65%) and SVM (15.42%)in terms of geometric mean-based prediction accuracy. T-test is used to examine whether the performance of each classifiers for 30 folds is significantly different. The results indicate that performance of MGM-Boost is significantly different from AdaBoost and SVM classifiers at 1% level. These results mean that MGM-Boost can provide robust and stable solutions to multi-classproblems such as bond rating.

Sequence driven features for prediction of subcellular localization of proteins

  • Kim, Jong-Kyoung;Bang, Sung-Yang;Choi, Seung-Jin
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.237-242
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    • 2005
  • Predicting the cellular location of an unknown protein gives a valuable information for inferring the possible function of the protein. For more accurate prediction system, we need a good feature extraction method that transforms the raw sequence data into the numerical feature vector, minimizing information loss. In this paper, we propose new methods of extracting underlying features only from the sequence data by computing pairwise sequence alignment scores. In addition, we use composition based features to improve prediction accuracy. To construct an SVM ensemble from separately trained SVM classifiers, we propose specificity based weighted majority voting. The overall prediction accuracy evaluated by the 5-fold cross-validation reached 88.53% for the eukaryotic animal data set. By comparing the prediction accuracy of various feature extraction methods, we could get the biological insight on the location of targeting information. Our numerical experiments confirm that our new feature extraction methods are very useful for predicting subcellular localization of proteins.

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Ensemble SVM Learning Using Margin Vector (마진 벡터를 이용한 앙상블 SVM의 학습)

  • Park, Sang-Ho;Kim, Tae-Soon;Park, Sun;Kang, Yun-Hee;Lee, Ju-Hong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2003.11a
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    • pp.301-304
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    • 2003
  • SVM은 일반화된 높은 분류 정확률을 보인다. 그러나, SVM은 데이터의 양이 커질수록 높은 시간 공간적 복잡성 때문에 근사화 알고리즘(Approximation Algorithm)을 이용한다. 이러한 접근 방법은 실제구현에서 높은 시간 공간적 복잡성을 요구하여 분류 정확률과 효율성을 낮아지게 한다. 따라서, 본 논문은 SVM을 앙상블 구조로 구성하여 분류 정확률을 높이고, 분류자의 최적 하이퍼플랜(Optimal Hyperplane)결정을 위해 마진 벡터만을 이용하여 시간 공간적 문제를 해결하였다. 실험결과, 본 논문에서 제시한 방법이 단일 SVM을 이용한 방법보다 높은 분류 정확률과 높은 효율성을 가짐을 보여준다...

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EUS SVMs: Ensemble of Under-Sampled SVMs for Data Imbalance Problems (데이터 불균형 해결을 위한 Under-Sampling 기반 앙상블 SVMs)

  • Gang Pil-Seong;Jo Seong-Jun
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2006.05a
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    • pp.291-298
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    • 2006
  • 패턴인식 문제에서 한 범주에 속한 데이터의 수가 다른 범주에 속한 데이터의 수보다 극히 많거나 적으면 데이터 불균형이 발생했다고 한다. Support Vector Machine(SVM)은 다른 기계 학습 알고리즘들과 마찬가지로 학습에 사용되는 데이터의 범주간 비율이 거의 비슷하다는 가정 하에서 학습을 하고 예측 결과를 도출하게 된다. 그러나 실제 문제에서는 데이터의 불균형이 발생하는 경우가 매우 빈번하며, 이러한 경우에는 모델의 성능이 매우 저하되는 문제점이 발생한다. 본 논문에서는 실제로 데이터 불균형이 SVM의 분류 결과에 어떠한 영향을 미치는지를 2차원 인공 데이터를 통하여 알아본다. 그리고 이러한 데이터 불균형을 해소하기 위하여 Under-Sampling 기반 앙상블 SVM을 제안하였다. 제안된 방법을 두 가지 인공 데이터에 적용하여 본 결과, 제안된 방법은 데이터 불균형을 해소하기 위해 사용되는 기존의 방법들에 비하여 소수 범주에 속하는 데이터의 수가 매우 적고 데이터의 불균형이 매우 심한 경우에도 높은 성능과 안정성을 갖는 효과적인 방법이라는 것이 입증되었다.

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Prediction of Cardiovascular Disease Steps using Support Vector Machine Ensemble (SVM 앙상블을 이용한 심혈관질환 질환단계 예측)

  • Eom Jae-Hong;Zhang Byoung-Tak
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.06a
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    • pp.76-78
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    • 2006
  • 현재 심혈관 질환은 암 다음으로 높은 사망 원인으로 기록되고 있어 심혈관 질환에 대한 초기 진단은 질환의 치료에 매우 중요한 문제로 대두되고 있다. 본 논문에서는 SVM을 이용하여 심혈관질환 환자의 질환 단계를 예측하였다. 일반적으로 이진분류에 사용되는 SVM을 이용하여 정상 및 질환 $1{\sim}3$기의 총 4가지 분류가 필요한 다분류 분류문제를 처리하기 위해서 논문에서는 독립적 학습된 단일 SVM 분류기들을 결합하여 분류를 수행하는 SVM 앙상블 방법을 사용하였다. 단일 분류기의 결합은 Majority voting, 최소자승에러기반 가중치 부여, 2단계층 결합 등의 방법으로 수행하여 심혈관 질환 분류에 적합한 앙상블의 구성을 시도하였다. 실험 데이터는 (주)제노프라의 압타머 칩 데이터를 사용하였다. 서로 다른 데이터를 이용하여 학습된 이종의 SVM들을 결합한 결과 질환단계 예측에 있어서 단일 SVM을 이용하여 질환 단계를 예측하는 경우 보다 향상된 질환단계 예측 성능을 관찰할 수 있었으며, 심혈관 질환의 예측에 대해서는 단일 SVM 분류기의 2단 계층 결합법이 가장 좋은 성능을 보임을 확인하였다.

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Data Assimilation for Oceanographic Application: A Brief Overview

  • Park, Seon-K.
    • Journal of the korean society of oceanography
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    • v.38 no.2
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    • pp.52-59
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    • 2003
  • In this paper, a brief overview on data assimilation is provided in the context of oceanographic application. The ocean data assimilation needs to ingest various types of data such as satellites and floats, thus essentially requires dynamically-consistent assimilation methods. For such purpose, sequential and variational approaches are discussed and compared. The major advantage of the Kalman filter (KF) is that it can forecast error covariances at each time step. However, for models with very large dimension of state vector, the KF Is exceedingly expensive and computationally less efficient than four-dimensional variational assimilation (4D-Var). For operational application, simplified 4D-Var schemes as well as ensemble KF may be considered.