• 제목/요약/키워드: enriched metadata

검색결과 2건 처리시간 0.015초

휴대용 멀티미디어 기기에서 메타데이터 활용을 강화한 파일 시스템 구조 (A File System Architecture for Enriched Metadata in Portable Multimedia Devices)

  • 윤현주
    • 대한임베디드공학회논문지
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    • 제2권1호
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    • pp.1-8
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    • 2007
  • In this paper, we developed a file system architecture for portable multimedia devices. To enhance user convenience, the information about the stored files should be easily retrieved and organized. We defined NMD (Networked MetaData), which can organize the files in networked fashion by attaching user-defined attributes and relation between files. The NMD is stored in flash memory to utilize its nonvolatile property and low-power consumption, while multimedia files are stored in hard disk, an inexpensive mass storage. The experimental implementation showed that this architecture was able to save about 10% power compared to the hard disk NMD-store.

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Reliability of microarray analysis for studying periodontitis: low consistency in 2 periodontitis cohort data sets from different platforms and an integrative meta-analysis

  • Jeon, Yoon-Seon;Shivakumar, Manu;Kim, Dokyoon;Kim, Chang-Sung;Lee, Jung-Seok
    • Journal of Periodontal and Implant Science
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    • 제51권1호
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    • pp.18-29
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    • 2021
  • Purpose: The aim of this study was to compare the characteristic expression patterns of advanced periodontitis in 2 cohort data sets analyzed using different microarray platforms, and to identify differentially expressed genes (DEGs) through a meta-analysis of both data sets. Methods: Twenty-two patients for cohort 1 and 40 patients for cohort 2 were recruited with the same inclusion criteria. The 2 cohort groups were analyzed using different platforms: Illumina and Agilent. A meta-analysis was performed to increase reliability by removing statistical differences between platforms. An integrative meta-analysis based on an empirical Bayesian methodology (ComBat) was conducted. DEGs for the integrated data sets were identified using the limma package to adjust for age, sex, and platform and compared with the results for cohorts 1 and 2. Clustering and pathway analyses were also performed. Results: This study detected 557 and 246 DEGs in cohorts 1 and 2, respectively, with 146 and 42 significantly enriched gene ontology (GO) terms. Overlapping between cohorts 1 and 2 was present in 59 DEGs and 18 GO terms. However, only 6 genes from the top 30 enriched DEGs overlapped, and there were no overlapping GO terms in the top 30 enriched pathways. The integrative meta-analysis detected 34 DEGs, of which 10 overlapped in all the integrated data sets of cohorts 1 and 2. Conclusions: The characteristic expression pattern differed between periodontitis and the healthy periodontium, but the consistency between the data sets from different cohorts and metadata was too low to suggest specific biomarkers for identifying periodontitis.