• Nutritional Sciences
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• 제4권1호
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• pp.47-54
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• 2001

This survey was carried out using a self-administered questionnaire in order to investigate the flavor enhancer products questionnaires were used out of 505 collected (collection rate : 84.2%). Most housewives used flavor enhancer products. Housewives with higher educations and employed housewives used significantly less flavor enhancer. The main reason for nonuse of flavor enhancer products was their perceived negative health effects. Housewives mainly used flavor enhancer products in stews and whole dishes. Most housewives used flavor enhancer products 1-2 times per day and housewives with higher educations and employed housewives used flavor enhancer products less frequently. As for the quantity of flavor enhancer products used, most housewives reported small to moderate amounts. Housewives with higher educations used significantly smaller amounts of flavor enhancer products. There was a significant difference in the kinds of flavor enhancer products used by housewives, depending on education level, household income, food expenditures and residence type. Most housewives purchased flavor enhancer products at wholesale marts. There was a significant difference in the places where flavor enhancer products were purchased among those of different education and household income levels. Therefore, these results may be useful in the development of safer and more variously flavored flavor enhancer products.

• BMB Reports
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• 제48권10호
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• pp.589-594
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• 2015

The shadow enhancer of the short gastrulation (sog) gene directs its sequential expression in the neurogenic ectoderm and the ventral midline of the developing Drosophila embryo. Here, we characterize three unusual features of the shadow enhancer midline activity. First, the minimal regions for the two different enhancer activities exhibit high overlap within the shadow enhancer, meaning that one developmental enhancer possesses dual enhancer activities. Second, the midline enhancer activity relies on five Single-minded (Sim)-binding sites, two of which have not been found in any Sim target enhancers. Finally, two linked Dorsal (Dl)- and Zelda (Zld)-binding sites, critical for the neurogenic ectoderm enhancer activity, are also required for the midline enhancer activity. These results suggest that early activation by Dl and Zld may facilitate late activation via the noncanonical sites occupied by Sim. We discuss a model for Zld as a pioneer factor and speculate its role in midline enhancer activity.

• BMB Reports
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• 제49권10호
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• pp.572-577
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• 2016

The short gastrulation (sog) shadow enhancer directs early and late sog expression in the neurogenic ectoderm and the ventral midline of the developing Drosophila embryo, respectively. Here, evidence is presented that the sog primary enhancer also has both activities, with the late enhancer activity dependent on the early activity. Computational analyses showed that the sog primary enhancer contains five Dorsal (Dl)-, four Zelda (Zld)-, three Bicoid (Bcd)-, and no Single-minded (Sim)-binding sites. In contrast to many ventral midline enhancers, the primary enhancer can direct lacZ expression in the ventral midline as well as in the neurogenic ectoderm without a canonical Simbinding site. Intriguingly, the impaired transcriptional synergy between Dl and either Zld or Bcd led to aberrant and abolished lacZ expression in the neurogenic ectoderm and in the ventral midline, respectively. These findings suggest that the two enhancer activities of the sog primary enhancer are functionally consolidated and geographically inseparable.

• 대한지역사회영양학회지
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• 제5권4호
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• pp.683-696
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• 2000

The purpose of this study was to investigate the perception and use of flavor enhancer products. This study was carried out through questionnaire and the subjects were 503 housewives in Inchon. The results are summarized as follows. As for age, 51.9% of the subjects were 40 years or older. Also, 60.0% of the subjects had received a high school education. As for occupation, full-time housewives accounted for 63.7%. Monthly household income of most subjects were 1 million won or more, and monthly food expenses of most subjects were 300 thousand won or more. Also 71.0% of subjects lived in apartments. As for taste of flavor enhancer products, 58.3% of subjects perceived that it was mediocre, 31.3% said good, 6.2% said bad, and 1.8% said very bad. Most subjects perceived that the convenience of flavor enhancer products was good and there was a significant difference among the groups divided by education level. As for economy of flavor enhancer products, there were significant differences among groups divided by household income and food expenses. Most subjects perceived that the safety of flavor enhancer products was not good. Most subjects considered the date of manufacture, manufacturers, food additives, packaging and price when they purchased flavor enhancer products. Also, 70.0% of subjects were going to reduce the amount of flavor enhancer products they use in the future. Most subjects needed flavor enhancer products good for health. Therefore, it may be necessary to develop and to produce safe, nutritious, tasty, cheap and various flavor enhancer products.

• Weed & Turfgrass Science
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• 제6권4호
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• pp.313-321
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• 2017

Wetting agent is designed to reduce the surface tension of the liquid and spread more easily across or penetrate into the soil against water repellency. The effect of wetting agent to seed germination is not clear. Using germination enhancer is one of the methods to increase the germination speed of turfgrass seeds and to shorten establishment period. The objective of the study was to evaluate germination enhancer and wetting agent for quick establishment of various Kentucky bluegrass cultivars. The germination enhancer was used at two levels of 0.3 and $0.6ml\;kg^{-1}$ as low and high, respectively. Two levels of wetting agent were of 0.46, and $0.92ml\;m^{-2}$ as low and high, respectively. Germination enhancer has no synergistic effect with wetting agent. When quick establishment is required, selection of cultivar would be more effective instead of using germination enhancer and wetting agent. Among Kentucky bluegrass cultivars, 'Award' had the greatest turfgrass coverage for establishment and the greatest turfgrass color and quality based on the result of the study. When quick establishment is required, selection of cultivar would be more effective instead of using germination enhancer and wetting agent.

• Environmental Analysis Health and Toxicology
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• 제20권3호
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• pp.229-235
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• 2005

태양광선,특히 자외선 B에 대한 환경적 노출은 편평세포암과 기저세포암을 포함하는 흑색선종 이외의 피부암과 크게 관련된다고 알려져 있다. 염기 류신 지퍼계 전사조절인자인 CChAT/enhancer binding protein-alpha는 표피 각질형성세포에서 다량으로 발현되었고, 각질형성세포의 증식을 억제하며 피부암 발생을 억제하는 유전자로서의 역할이 암시된 바 있다. 최근 자외선 B가 각질형성세포에서 p53에 의한 CCAAT/enhanrer binding protein-alpha의 발현을 강력하게 유도한다는 것이 보고되었다. 이러한 CCAAT/enhancer binding protein-alpha 단백질 발현의 유도는 세포 성장 억제 세포고사와 함께 일어났다. 이 연구는 glycogen synthase kinase-3 길항제가 자외선 B에 의한 CCAAT/enhancer binding protein-alpha 유도를 억제하며 변이 kinase-불활성 GSK의 강제 발현은 자외선 B가 CCAAT/enhancer binding protein-alpha전사조절부위 활성의 증가를 억제한다는 것을 보여주었다. 즉 자외선 B에 의한 CCAAT/enhancer binding protein-alpha의 유도가 p53과 활성 glycogen synthase kinase-3에 의한 것이라는 것을 증명하였다.

• 디지털콘텐츠학회 논문지
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• 제5권1호
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• pp.79-86
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• 2004

본 논문에서는 고해상도 FPD(Flat Panel Display)에서 동영상의 화질 향상을 위한 실시간 Contrast Enhancer 알고리즘을 제안하고 이를 구현하였다. 또한 입력되는 영상신호의 밝기 분포에서 영상의 평균과 분산을 이용하여 적응적으로 처리하는 적응형 콘트라스트 제어 기법을 제안하였다. 설계된 Contrast Enhancer는 기존화면과 비교하여 정량적으로 측정하였으며, 실제 유용성을 검증하기 위해 LG의 30인치 TFT-LCD TV에 인터페이스하여 구현하였다.

• BMB Reports
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• 제30권4호
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• pp.269-273
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• 1997

Heptocvte-specific expression induced by Hepatitis B virus (HBV) enhancer 2-core gene promoter was examined in various hepatocyte and non-hepatocyte cell lines. using non-viral and retroviral vector systems in which chloramphenicol acetyltransferase (CAT) is used as a reporter. The non-viral plasmid containing the HBV enhancer 2-core promoter exhibited 22 and 66% of CAT activities in hepatoma cell lines. HepG2 and Hep3B, respectively when compared with CAT activity expressed by CMV promoter. The CAT activities, however. were found to be marginal in other tested hepatoma cell lines as well as mouse primary hepatocytes and non-hepatocytes. The HBV enhancer 2 located upstream the CMV promoter did not affect the CMV promoter activity nor provided hepatocyte-specific expression. Transfection of retroviral plasmid DNA containing the HBV enhancer 2-core promoter as an internal promoter exhibited high and specific CAT expression in HepG2 and Hep3B cell lines but the activity value was 5 to 10 fold lower than the non-viral plasmid with identical promoter. These results suggest that the usage of HBV enhancer 2-core promoter for liver specific expression is limited to certain vectors and hepatocyte cell lines.

• Molecules and Cells
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• 제38권11호
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• pp.1007-1012
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• 2015

EphA7 is a key molecule in regulating the development of the dien- and mesencephalon. To get insight into the mechanism of how EphA7 gene expression is regulated during the dorsal specification of the dien- and mesencephalon, we investigated the cis-acting regulatory sequence driving EphA7 to the dorsal midline of the dien- and mesencephalon. Transgenic LacZ reporter analysis, using overlapping EphA7 BACs, was used to narrow down the dorsal midline-specific enhancer, revealing the 25.3 kb genomic region as the enhancer candidate. Strikingly, this genomic DNA was located far downstream of the EphA7 transcription start site, +302.6 kb to +327.9 kb. Further enhancer mapping, using comparative genomic analysis and transgenic methods, showed that the 187 bp genomic DNA alone, approximately 305 kb downstream of the EphA7 transcription start site, was sufficient to act as the dorsal midline-specific enhancer of EphA7. Importantly, our results indicate that the 187 bp dorsal midline-specific enhancer is critically regulated by homeobox transcription factors during the development of the dien- and mesencephalon.

• 한국자기공명학회논문지
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• 제20권4호
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• pp.121-128
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• 2016

Bean sprouts are often cultivated in the circumstances prevailing in the improper using of germicide and growth enhancer. The influence of ingestion those bean sprouts are unknown. The components of the bean sprouts are needed to evaluate for food safety. The extracts of the control, 0.5 g/L germicide, 1 g/L germicide, 12.5 mL/L growth enhancer and 25 mL/L growth enhancer were used to compare the components in the experiment. Nuclear Magnetic Resonance spectroscopy (NMR) was used to analyze the extracts. Statistical analysis of metabolomics showed significant changes between the control and head and the stem of the bean sprouts. Significant changes in metabolites were identified with the bean sprouts cultivated with germicide and growth enhancer by applying qualitative and quantitative analysis. Similar changes in the area of the bean sprouts were observed after treated to germicide and growth enhancer. Although treating germicide and growth enhancer showed no particular harmful metabolites changes to human, it made significant changes in the morphological and the metabolites of the bean sprouts. These changes indicate that the germicide and growth enhancer has substantially potential to influence the growth of the bean sprouts.