• Journal of Life Science
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• v.22 no.4
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• pp.456-465
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• 2012

Heterodimeric recombinant human bone morphogenetic proteins (rhBMPs) are powerful tools for bone tissue engineering. However, BMPs have several important limitations in their application to bone regeneration. BMPs have a short half-life and must be used in high concentrations, which may be cost-inefficient. To overcome these problems, we established a stable cell line that expressed the fusion protein comprised of recombinant human BMP2/7 heterodimer protein and PTD (rhBMP2/7-PTD). This stable cell line enabled high process yields by continuously expressing rhBMP2/7-PTD products at high levels throughout cultivation. This synthesized BMP7 was fused to a BMP2 protein with four glycine residues (to allow free bond rotation of the domains) and PTD. To demonstrate that the rhBMP2/7-PTD protein that was secreted from an rhBMP2/7-PTD-expressing stable cell line exhibited biological activity consistent with its role as an osteogenic differentiation induction growth factor, we evaluated BMP-induced ALP activity. Our results suggest that this cell line may be a powerful and efficient tool for applications such as bone tissue regeneration.

• Journal of Korean Society for Atmospheric Environment
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• v.28 no.5
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• pp.571-580
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• 2012

Epidemiologic studies of air pollution need accurate exposure assessments at unmonitored locations. A land use regression (LUR) model has been used successfully for predicting traffic-related pollutants, although its application has been limited to Europe, North America, and a few Asian region. Therefore, we modeled traffic-related pollutants by LUR then examined whether LUR models could be constructed using a regulatory monitoring network in Metropolitan area in Korea. We used the annual-mean nitrogen dioxide ($NO_2$) in 2010 in the study area. Geographic variables that are considered to predict traffic-related pollutants were classified into four groups: road type, traffic intensity, land use, and elevation. Using geographical variables, we then constructed a model to predict the monitored levels of $NO_2$. The mean concentration of $NO_2$ was 30.71 ppb (standard deviation of 5.95) respectively. The final regression model for the $NO_2$ concentration included five independent variables. The LUR models resulted in $R^2$ of 0.59. The mean concentration of $NO_2$ of elementary schools was 34.04 ppb (standard deviation of 5.22) respectively. The present study showed that even if we used regulatory monitoring air quality data, we could estimate $NO_2$ moderately well. These analyses confirm the validity of land use regression modeling to assign exposures in epidemiological studies, and these models may be useful tools for assessing health effects of long-term exposure to traffic related pollution.

• Journal of the Korean Association of Geographic Information Studies
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• v.14 no.1
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• pp.94-106
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• 2011

The muddy water occurrence possibility of reservoir were analyzed by considering GIS based soil erosion model, sediment delivery ratio and effective reservoir capacity. For the purpose, the weakness factors for the establishment of countermeasures of basin were analyzed by evaluating input factors of RUSLE model based on spatial data such as DEM, soil map, landcover map and so on. The potential of soil erosion was estimated considering highland upland. The sediment yields of Chungju-Dam and Soyanggang-Dam showed the highest result in sediment yield using sediment delivery ratio with considering basin area. The sediment concentration of Imha-Dam and Chungju-Dam showed the highest value as 0.791 $kg/m^3/yr$ and 0.526 $kg/m^3/yr$ respectively in sediment concentration with considering effective reservoir capacity. Especially, sediment yield of Imha-Dam was about 2.36 times lower than Soyanggang-Dam, but the sediment concentration was 1.90 times higher preferably, because the effective reservoir capacity of Imha-Dam was about 4.48 times lower. This study calculated sediment concentration using the 10 years mean rainfall event and could consider the aspects of soil, terrain, landcover, cultivation condition and effective reservoir capacity of each basin effectively through the results. Therefore, these quantitative sediment concentration data could be used to estimate the potential of high density turbid water for reservoir and applied with effective tools for the management of reservoir.

• Journal of Broadcast Engineering
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• v.23 no.1
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• pp.45-52
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• 2018

The virtual reality (VR) cartoon is a format of VR contents that leverage the characteristics of webtoons that provides the simple story line and graphical storytelling tools to strategically surmount limitations of VR contents design. The VR cartoon enables people to experience the imaginary three-dimensional space in the webtoon as a real space by the transformation of webtoon contents through VR prototyping. The VR cartoon successfully presents focused environment where people can readily pay attention to the contents without notable motion sickness. People have been familiar with the storytelling strategy in the context of published cartoons and webtoons, likely we've understood the narrative of a movie through the continuous scenes projected in the screen. Indeed, it has been recognized as a popular toolset of communication, where visual images are sequentially delivered by replacing multiple planar spaces to tell a story narrative. While there are discrete panels with the time and space resolution in the graphical cartoons, people can distill a commit closure based on their past experiences. This is a typical "grammar" of the cartoon, which can be extrapolated to the VR cartoon that provides a seminal storytelling strategy. In this article, we review how the storytelling strategy in webtoons has been transformed into that in VR cartoons, and analyze the key components of VR cartoons. We envision that our research can potentially create keystones to produce variety of new VR contents by reflecting various narrative media including cartoon as a 'sequential art'.

• Journal of Broadcast Engineering
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• v.22 no.4
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• pp.484-495
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• 2017

The development of display devices and the increase of network transmission bandwidth bring demands for over 2K high resolution video such as panorama video, 4K ultra-high definition commercial broadcasting, and ultra-wide viewing video. To compress these image sequences with significant amount of data, High Efficiency Video Coding (HEVC) standard with the highest coding efficiency is a promising solution. HEVC, the latest video coding standard, provides high encoding efficiency using various advanced encoding tools, but it also requires significant amounts of computation complexity compared to previous coding standards. In particular, the complexity of HEVC decoding process is a imposing challenges on real-time playback of ultra-high resolution video. To accelerate the HEVC decoding process for ultra high resolution video, this paper introduces a data-level parallel video decoding method using slice and/or tile supported by HEVC. Moreover, deblocking filter process is further parallelized. The proposed method distributes independent decoding operations of each tile and/or each slice to multiple threads as well as deblocking filter operations. The experimental results show that the proposed method facilitates executions up to 2.0 times faster than the HEVC reference software for 4K videos.

• Proceedings of the Korean Vacuum Society Conference
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• 2016.02a
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• pp.77-77
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• 2016

Thin films synthesized by plasma processes have been widely applied in a variety of industrial sectors. The structure control of thin film is one of prime factor in most of these applications. It is well known that the structure of this film is closely associated with plasma parameters and species of plasma which are electrons, ions, radical and neutrals in plasma processes. However the precise control of structure by plasma process is still limited due to inherent complexity, reproducibility and control problems in practical implementation of plasma processing. Therefore the study on the fundamental physical properties that govern the plasmas becomes more crucial for molecular scale control of film structure and corresponding properties for new generation nano scale film materials development and application. The thin films are formed through nucleation and growth stages during thin film depostion. Such stages involve adsorption, surface diffusion, chemical binding and other atomic processes at surfaces. This requires identification, determination and quantification of the surface activity of the species in the plasma. Specifically, the ions and neutrals have kinetic energies ranging from ~ thermal up to tens of eV, which are generated by electron impact of the polyatomic precursor, gas phase reaction, and interactions with the substrate and reactor walls. The present work highlights these aspects for the controlled and low-temperature plasma enhanced chemical vapour disposition (PECVD) of Si-based films like crystalline Si (c-Si), Si-quantum dot, and sputtered crystalline C by the design and control of radicals, plasmas and the deposition energy. Additionally, there is growing demand on the low-temperature deposition process with low hydrogen content by PECVD. The deposition temperature can be reduced significantly by utilizing alternative plasma concepts to lower the reaction activation energy. Evolution in this area continues and has recently produced solutions by increasing the plasma excitation frequency from radio frequency to ultra high frequency (UHF) and in the range of microwave. In this sense, the necessity of dedicated experimental studies, diagnostics and computer modelling of process plasmas to quantify the effect of the unique chemistry and structure of the growing film by radical and plasma control is realized. Different low-temperature PECVD processes using RF, UHF, and RF/UHF hybrid plasmas along with magnetron sputtering plasmas are investigated using numerous diagnostics and film analysis tools. The broad outlook of this work also outlines some of the 'Grand Scientific Challenges' to which significant contributions from plasma nanoscience-related research can be foreseen.

• KDI Journal of Economic Policy
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• v.14 no.1
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• pp.61-87
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• 1992

Reducing the level of greenhouse gas emissions is necessary to mitigate global warming. One of the most feasible methods to reduce emissions would be to conserve energy and substitute fossil fuels. Yet reducing emissions entails huge financial costs, so it is advisable to employ cost-effective economic instruments such as a carbon tax or tradeable emissions permits. Assuming that the proper economic tools will be used in the future, we calculated the optimal level of emissions reduction for Korea. We applied to our cost-benefit analysis Nordhaus' scenario regarding the economic damage from a $3^{\circ}C$ rise in global temperatures, which is the calculated result when the greenhouse gas level doubles. The result of our analysis based on the 1990 data indicates that the optimal level of emissions reduction ranges from 2% to 15 % of current emissions depending on the value of damage parameters. We also found that the amount of emissions must be reduced will increase if action is postponed, when the development of climate engineering technology or more efficient use of energy is expected. In addition, we discussed the advantages and disadvantages of the economic instruments available to implement emissions reduction. Tradeable permits and carbon tax are equivalent in their cost-effectiveness, but have different implications in practice.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1329-1338
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• 2015

This article aims to develop model for the right policy Tools available from the cause analysis regarding the regional differences of subway modal split in Seoul metropolitan area. This allows two major factors of the most influential subway modal split to be proved and Portfolio Analysis is conducted. The results are as follows. Firstly, the two primary factors affecting subway modal split were shown as subway adjacent area and local line bus. It signifies that expansion of subway adjacent area, establishing the number of the subway stations and increase of local line bus are required in order to improve a diminishing subway modal split. Following that, pattern of the improvement to strengthen better subway connections are classified according to the two areas which are Concentration Area of Improvement in Subway Station Area (CAISSA) and Concentration Area of Improvement in Local Bus (CAILB). Our study revealed that Ganbukgu, Seodaemungu, Geumcheongu, and Gwanakgu were selected as the area of CAILB and Songpagu, and Junggu were selected as the area of CAISSA. As all things are considered, transportation policy makers should be taken into account in the two main factors driven by our study according to types in order to enhance the future subway share proportion.

• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.227-231
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• 2006

As for comics and animation, the specific gravity came to become still larger in all the art fields together with the importance in various image media now which is useful and goes the time of the 21st century new media. Especially the demand of users to the vision culture which develops day by day, Sensitivity Engineering Department is trying to realize the necessity for a sensitivity design acutely together. The influence of the comics which have toxicity most also in Japanese culture in a geographical position like South Korea on it, and animation is the actual condition in the reason which has reached from youth universally to the layer for years, to be inquired systematic to a Korean comics language. This reserch was conducted as we thought sufficient study on various situations are required, and among them, for the reserch of expressions of cartoons's characters, we've divided the expressions of characters that comes out in Japanese cartoons into catagories of "happiness, anger, sadness, pleasure" and "fear, astonishment and dislike" and based on these catagories, we've drawn out the minimum elements to express emotions in cartoon and prepared image-map by relating them with languages that express emotions of people and based on this, we've made a calculating tools on how our readers would read the expression languages. Samples of Japanese cartoons of which we've chosen for the purpose of drawing out the elements of expressions were limited to only published cartoons and we've made a foot steps for expression analysis of animation characters in the future.

• Journal of the Korean Association of Geographic Information Studies
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• v.3 no.2
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• pp.1-10
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• 2000

The purpose of this study is to develope a parcel-based automatic simulation system of land price through the integration of urban mathematical model and GIS. The appraisal process of public land price by the local government is simple but is a great time-consuming task. Moreover, it doesn't provide any statistical analysis and spatial presentation tools. So, it is difficult for planners or administrative officials to analyze the variation of land price with spatial idea. From these, a system is developed combining two sub-systems, they are ANN(Artificial Neural Network) for the calculation of land price and GIS for visual presentation. Using Matlab application, ANN model was designed having 3-layer structure and was trained with the sample data taken from Chinju city. With the trained network, the impact of 'road', 'parks', 'height control district' and 'beauty district' on land price in 9 regions(dong) are simulated. The results of the simulation were visualized with ArcView GIS. The automatic simulation system operated through the DDE(Dynamic Data Exchange) conversation between two applications. ArcView was set as client and Matlab as server. Scripting in ArcView and customizing a window of ArcView, this system can execute the whole process of simulation by just clicking a button with mouse. As a conclusion, this system was proved to be an effective and easily controllable planning support system for the land price simulation.