• Journal of Ginseng Research
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• v.43 no.2
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• pp.305-311
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• 2019

Background: Gintonin is a ginseng-derived exogenous ligand of the G protein-coupled lysophosphatidic acid (LPA) receptor. We previously reported that gintonin stimulates gliotransmitter release in primary cortical astrocytes. Astrocytes play key roles in the functions of neurovascular systems. Although vascular endothelial growth factor (VEGF) is known to influence the normal growth and maintenance of cranial blood vessels and the nervous system, there is little information about the effect of gintonin on VEGF regulation in primary astrocytes, under normal and hypoxic conditions. Methods: Using primary cortical astrocytes of mice, the effects of gintonin on the release, expression, and distribution of VEGF were examined. We further investigated whether the gintonin-mediated VEGF release protects astrocytes from hypoxia. Results: Gintonin administration stimulated the release and expression of VEGF from astrocytes in a concentration- and time-dependent manner. The gintonin-mediated increase in the release of VEGF was inhibited by the LPA1/3 receptor antagonist, Ki16425; phospholipase C inhibitor, U73122; inositol 1,4,5- triphosphate receptor antagonist, 2-APB; and intracellular $Ca^{2+}$ chelator, BAPTA. Hypoxia further stimulated astrocytic VEGF release. Gintonin treatment stimulated additional VEGF release and restored cell viability that had decreased due to hypoxia, via the VEGF receptor pathway. Altogether, the regulation of VEGF release and expression and astrocytic protection mediated by gintonin under hypoxia are achieved via the LPA receptor-VEGF signaling pathways. Conclusion: The present study shows that the gintonin-mediated regulation of VEGF in cortical astrocytes might be neuroprotective against hypoxic insults and could explain the molecular basis of the beneficial effects of ginseng on the central nervous system.

• KIPS Transactions on Software and Data Engineering
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• v.8 no.5
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• pp.213-222
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• 2019

Determining the meaning of a keyword in a speech dialogue system is an important technology for the future implementation of an intelligent speech dialogue interface. After extracting keywords to grasp intention from user's utterance, the intention of utterance is determined by using the semantic mark of keyword. One keyword can have several semantic marks, and we regard the task of attaching the correct semantic mark to the user's intentions on these keyword as a problem of word sense disambiguation. In this study, about 23% of all keywords in the corpus is manually tagged to build a semantic mark dictionary, a synonym dictionary, and a context vector dictionary, and then the remaining 77% of all keywords is automatically tagged. The semantic mark of a keyword is determined by calculating the context vector similarity from the context vector dictionary. For an unregistered keyword, the semantic mark of the most similar keyword is attached using a synonym dictionary. We compare the performance of the system with manually constructed training set and semi-automatically expanded training set by selecting 3 high-frequency keywords and 3 low-frequency keywords in the corpus. In experiments, we obtained accuracy of 54.4% with manually constructed training set and 50.0% with semi-automatically expanded training set.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.863-871
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• 2018

Existing vulnerability analysis tools are prone to missed detections, incorrect detections, and over-detection, which reduces accuracy. In this paper, cross-checking based on a vulnerability detection method using static and dynamic analysis is proposed, which develops and manages safe applications and can resolve and analyze these problems. Risks due to vulnerabilities are computed, and an intelligent vulnerability detection technique is used to improve accuracy and evaluate risks under the final version of the application. This helps the development and execution of safe applications. Through incorporation of tools that use static analysis and dynamic analysis techniques, our proposed technique overcomes weak points at each stage, and improves the accuracy of vulnerability detection. Existing vulnerability risk-evaluation systems only evaluate self-risks, whereas our proposed vulnerability risk-evaluation system reflects the vulnerability of self-risk and the detection accuracy in a complex fashion to evaluate relative. Our proposed technique compares and analyzes existing analysis tools, such as lists for detections and detection accuracy based on the top 10 items of SANS at CWE. Quantitative evaluation systems for existing vulnerability risks and the proposed application's vulnerability risks are compared and analyzed. We developed a prototype analysis tool using our technique to test the application's vulnerability detection ability, and to show that our proposed technique is superior to existing ones.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.41 no.4
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• pp.441-447
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• 2021

Construction sites are complex and dangerous because heavy equipment and workers perform various operations simultaneously within limited working areas. Solitary works of heavy equipment in complex job sites can cause fatal accidents, and thus they should interact with spotters and obtain information about surrounding environments during operations. Recently, many computer vision technologies have been developed to automatically monitor construction equipment and detect their interactions with other resources. However, previous methods did not take into account the interactions between equipment and spotters, which is crucial for identifying solitary works of heavy equipment. To address the drawback, this research develops a computer vision-based solitary work detection model that considers interactive operations between heavy equipment and spotters. To validate the proposed model, the research team performed experiments using image data collected from actual construction sites. The results showed that the model was able to detect workers and equipment with 83.4 % accuracy, classify workers and spotters with 84.2 % accuracy, and analyze the equipment-to-spotter interactions with 95.1 % accuracy. The findings of this study can be used to automate manual operation monitoring of heavy equipment and reduce the time and costs required for on-site safety management.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.9 no.6
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• pp.701-709
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• 2019

Recently, heart rate signal, which is one of biological signals, have been used in various fields related to healthcare. Conventionally, most of the proposed heart rate signal detection methods are contact type methods, but there is a problem of discomfort that the subject have to contact with the device. In order to solve the problem, detection study by non-contact method has been progressed recently. The detected heart rate signal can be used for finger vein liveness detection and various application using heart rate. In this paper, we propose a method to obtain heart rate signal by using finger vein imaging system. The proposed method detected the signal from the changes of the brightness value in the time domain of the infrared finger vein images and converted it into the frequency domain using the image processing algorithm. After the conversion, we removed the noise not related to the heart rate signal through band-pass filtering. In order to evaluate the accuracy of the signal, we analyzed the correlation with the signal obtained simultaneously with the finger vein acquisition device and contact type PPG sensor approved by KFDA. As a result, it was possible to confirm that the heart rate signal detected in non-contact method through the finger vein image coincides with the waveform of actual heart rate signal.

• KIPS Transactions on Software and Data Engineering
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• v.10 no.8
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• pp.287-300
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• 2021

Collaborative Cyber-Physical Systems (CCPS) are those systems that contain tightly coupled physical and cyber components, massively interconnected subsystems, and collaborate to achieve a common goal. The safety of a single Cyber-Physical System (CPS) can be achieved by following the safety standards such as ISO 26262 and IEC 61508 or by applying hazard analysis techniques. However, due to the complex, highly interconnected, heterogeneous, and collaborative nature of CCPS, a fault in one CPS's components can trigger many other faults in other collaborating CPSs. Therefore, a safety assurance technique based on fault criticality analysis would require to ensure safety in CCPS. This paper presents a Fault Criticality Matrix (FCM) implemented in our tool called CPSTracer, which contains several data such as identified fault, fault criticality, safety guard, etc. The proposed FCM is based on composite hazard analysis and content-based relationships among the hazard analysis artifacts, and ensures that the safety guard controls the identified faults at design time; thus, we can effectively manage and control the fault at the design phase to ensure the safe development of CPSs. To justify our approach, we introduce a case study on the Platooning system (a collaborative CPS). We perform the criticality analysis of the Platooning system using FCM in our developed tool. After the detailed fault criticality analysis, we investigate the results to check the appropriateness and effectiveness with two research questions. Also, by performing simulation for the Platooning, we showed that the rate of collision of the Platooning system without using FCM was quite high as compared to the rate of collisions of the system after analyzing the fault criticality using FCM.

• Tunnel and Underground Space
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• v.31 no.4
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• pp.243-269
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• 2021

Since the early 2010s, the social importance of research and practical projects targeting deep geological disposal of high-level nuclear waste, underground CO₂ storage and characterization of deep subsurface by borehole investigation has been increasing. In this regard, there is also a significant increase in the need for in situ test technology to obtain quantitative and reliable information on the hydraulic characteristics of deep rock mass. Through years of research and development, we have independently set up Deep borehole Hydraulic Test System (DHTS) based on the key apparatuses designed and made with our own technology. Using this system, high precision constant pressure injection tests were successfully completed at the two 1 km boreholes located in Mesozoic granite and sedimentary rock regions, Gyeongju. During the field tests, it was possible to measure very low flow rate below 0.01 l/min with micro flow rate injection/control module. In this paper, the major characteristics of DHTS are introduced and also some results obtained from the high precision field tests under the deep and low permeable rock mass environment are briefly discussed.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.3
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• pp.525-532
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• 2021

In the ocean, it is difficult to separate the effects of one cause due to the multiple causes, but the self-organizing map can be analyzed by adding other factors to the cluster result. Therefore, in this study, the results of the clustering of sea level data were applied to sea surface temperature. Sea level data was clustered into a total of 6 nodes. The difference between sea surface temperature and sea level height has a one-month delay, which applied sea surface temperature data a month ago to the clustered results. As a result of comparing the mean of sea surface temperature of 140 to 150°E, where the sea surface temperature was variously distributed, in the case of nodes 1, 3, and 5, it was possible to find a meandering sea surface temperature distribution that is clearly distinguished from the sea level data. While nodes 2, 4 and 6, the sea surface temperature distribution was smooth. In this study, sea surface temperature data were applied to the clustered results of sea level data, but later it is necessary to apply wind or geostrophic velocity data to compare.

• KIPS Transactions on Software and Data Engineering
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• v.10 no.5
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• pp.195-200
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• 2021

Due to the development of video sharing platforms, the amount of video uploads is exploding. Such videos often include various types of music, among which cover songs are included. In order to protect the copyright of music, an algorithm to find the original song of the cover song is essential. However, it is not easy to find the original song because the cover song is a modification of the composition, speed and overall structure of the original song. So far, there is no known effective algorithm for searching the original song of the cover song. In this paper, we propose an algorithm for searching the original song of the cover song using the inflection points of the melody line. Inflection points represent the characteristic points of change in the melody sequence. The proposed algorithm compares the original song and the cover song using the sequence of inflection points for the representative phrase of the original song. Since the characteristics of the representative phrase are used, even if the cover song is a song made by modifying the overall composition of the song, the algorithm's search performance is excellent. Also, since the proposed algorithm uses only the features of the inflection point sequence, the memory usage is very low. The efficiency of the algorithm was verified through performance evaluation.

• Journal of Broadcast Engineering
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• v.26 no.5
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• pp.500-507
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• 2021

The virtual reality industry has an opportunity to take another leap forward with the surge in demand for non-face-to-face content and interest in the metaverse after Covid-19. Therefore, in order to popularize virtual reality content along with this trend, high-quality content production and storytelling research suitable for the characteristics of virtual reality should be continuously conducted. In order for content to which virtual reality characteristics are applied to be effectively produced through user feedback, a quantitative index that can evaluate the content is needed. In this study, the process of viewing virtual reality contents was analyzed and head movement was set as a quantitative indicator. Afterwards, the experimenter watched five animations and analyzed the correlation between recorded head movement information and immersion. As a result of the analysis, high immersion was shown when the head movement speed was relatively slow, and it was found that the head movement speed can be used significantly as an index indicating the degree of content immersion. The result derived in this way can be used as a quantitative indicator that can verify the validity of the storytelling method applied after the prototype is produced when the creator creates virtual reality content. This method can improve the quality of content by quickly identifying the problems of the proposed storytelling method and suggesting a better method. This study aims to contribute to the production of high-quality virtual reality content and the popularization of virtual reality content as a basic research to analyze immersion based on the quantitative indicator of head movement speed.