• 제목/요약/키워드: endogenous factors

검색결과 277건 처리시간 0.024초

${\ll}$소문(素問).거통론(擧痛論)${\gg}$에 나타난 구기(九氣)에 대(對)한 고찰(考察) (Bibliographical study on the Jiu Qi(九氣) shown at Ju Tong Lun(擧痛論) in Shao Wen(素問) Huang Ti Nei Ching(黃帝內經))

  • 김보경;이상용
    • 동의신경정신과학회지
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    • 제11권1호
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    • pp.145-167
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    • 2000
  • Jiu Qi(九氣) was shown at Ju Tong Lun(擧痛論) in Shao Wen(素問) Huang Ti Nei Ching(黃帝內經), and is nine important factors that affect the function of human body. Jiu Qi concludes endogenous, exogenous, non-endo-exogenous factors. I do the bibliographical study on the Jiu Qi, the results were as follows; 1. The Qi of Jiu Qi has two opposite meanings. one is genuine vital energy(正氣), and the other is the factors causing abnormal state in vital energy. Jiu Qi is nine factors concluding coldness-heat(exogenous factors). six emotional factors(endogenous factor), overworking(non -endo-exogenous factor). 2. Anger may lead to abnormal rising of vital energy. Anger causes Qi of the liver to go perversely upward, and perverted flow of exuberant Qi of the liver lead to dysfunction of the spleen, so resulted in hematemesis, diarrhea, indigestion. 3. Joy can promote the harmony of vital energy and blood, so do the circulation of nutrient and defensive energy in physiological state. But an excessive joy may lead to the sluggishness of vital energy. 4. The lung keeps the pathway of air unconstructed, disseminates vital energy, cleanses the inspired air and keeps vital energy flowing downward. Sorrow affects on the function of the lung and the heart, so could result in obstruction of the circulation of nutrient and defensive energy. An excessive sorrow after stagnation may lead to the consumption of vital energy. 5. Fear makes vital energy and essence of the kidney sink to inward and downside, makes Yang-Qi can't go upward, so causes obstruction of triple wanner. An excessive fear can obstructs the ascending of Yang-Qi, so may lead to the abnormal falling of vital energy. 6. Coldness makes the sweat pore be contracted, so obstructs the circulation of triple warmer, causes sluggishness of defensive energy or Qi of the internal organ. 7. Heat makes the sweat pore be open, much amount of sweat is excreted with Yang-Qi, defensive energy, vital energy. Heat may consume vital energy. 8. Sudden fright affects on spirits of the heart and liver, causes disorder of the mental faculties and separation of blood and vital energy. Fright may lead to disorder of Qi. 9. Overwork concludes overfatigue and exhaustion caused by intemperance in sexual life. Overwork renders vital energy consumed, and hence results in lassitude and listlessness. 10. Thinking affects on the function of the heart and the spleen. Over thinking may lead to depression of vital energy. Through the bibliographical study on Jiu Qi, I got smallest amount of it, and this must be more investigated correlating with clinical study.

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도시공원 이용만족도에 기초한 도시공원의 개발방향에 관한 연구 - 부산시 대신자연공원을 사례로- (A Study on the Developmental Direction with Reference to User's Satisfaction of Urban Park -Cases study of Daeshin Natural Park in Pusan City-)

  • 임승범
    • 한국조경학회지
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    • 제19권3호
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    • pp.87-97
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    • 1991
  • The primary purpose of this study is to investigate factors and variables which have significant effects on user's satisfaction with recreational activities in Daeshin Natural Park, thereby establishing directions of development of urban parks. To test the causal models of this research, the data were gathered by self-administered questionnaires form 627 households in Pusan City which were selected by the multi-stage probability sampling method. The analysis of the data primarily consists of two-phase: The first analysis dealt exploratory factor analysis which identified major factors involved in satisfaction with recreational activities in Daeshin Natural Park and the second analysis tested the fit of the causal models of this research by employing LISREL methodology. The factor analysis identified that three factors are involved in satisfaction with recreational actitives. The three factors of satisfaction with recreational activities are facilities for health and phisical exercise, group recreational activity, maintenance activity. The second phase analysis tested the fit of the causal models for satisfaction with recreational activity to the data and identified statistically significant causal linkage among overall satisfaction with Daeshin Natural Park, other endogenous factors and exogenous variables.

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노인요양 시설 입소 노인 삶의 질 구조모형 (A Structural Equation Model of Quality of Life in Nursing Home Residents)

  • 신소홍;박정숙
    • 노인간호학회지
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    • 제20권3호
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    • pp.193-203
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    • 2018
  • Purpose: This study was done to develop a predictive model for quality of life of elderly residents in long-term care facilities (LTCF). The study was based on Brofenbrenner's ecological system theory and a literature review. Methods: Data were collected using a convenience sample of 205 elderly residents in 2 nursing homes located in D city and 1 nursing home located in K province. The exogenous variables were individual factors, family support, and facility environmental factors. The endogenous variables were self-esteem, accommodation adaptation and quality of life of elderly residents in LTCF. Collected data were analyzed through structural equation modeling using AMOS 20.0. Results: Eleven of the twelve hypotheses were supported, but the hypothesis that facility environment factors effect self-esteem was not supported. Quality of life of elderly residents in LTCF was explained first by facility environmental factors, followed by self-esteem, individual factors, accommodation adaptation, and family support with an explanatory power of 83.0%. Conclusion: To improve the quality of life of elderly residents in LTCF, the service and environment preparation provided by facilities is important, and it is necessary to provide emotional counseling to improve the self-esteem of these elders.

Analysis of the Structural Relationships among Self-efficacy, Experience, Mobile Learning Quality, and Learner Satisfaction in Universities

  • LEE, Jong-Yeon;PARK, Sanghoon
    • Educational Technology International
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    • 제17권2호
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    • pp.203-228
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    • 2016
  • This study was designed to determine the factors affecting learner satisfaction and examine the relationships of these factors in mobile learning linked to pre-existing e-learning in universities. In the structural model used, three mobile learning quality factors are the endogenous variables, namely, system quality (SYQ), information quality (INQ) and service quality (SEQ) perceived by students, and learner satisfaction (LS), whereas students' self-efficacy (SE) and experience (EX) in mobile learning are the exogenous variables. The subjects were 900 students who registered for mobile learning courses offered by a private university in Seoul, Korea. The results indicated that SE in mobile learning had positive effects on SYQ, INQ, and SEQ. Furthermore, SE influenced LS when analyzed without quality factors as parameters. Mobile learning EX directly affected INQ, but not SYQ or SEQ. EX likewise had a direct effect on LS when analyzed without quality factors as parameters. Meanwhile, both SYQ and INQ showed a positive effect on LS, but not SEQ. SE and EX affected LS indirectly when SYQ and INQ were used as parameters. This study addresses the importance of increasing SE, EX, SYQ, and INQ to increase LS in mobile learning in universities

Enhanced Healing of Rat Calvarial Bone Defects with Hypoxic Conditioned Medium from Mesenchymal Stem Cells through Increased Endogenous Stem Cell Migration via Regulation of ICAM-1 Targeted-microRNA-221

  • Chang, Woochul;Kim, Ran;Park, Sang In;Jung, Yu Jin;Ham, Onju;Lee, Jihyun;Kim, Ji Hyeong;Oh, Sekyung;Lee, Min Young;Kim, Jongmin;Park, Moon-Seo;Chung, Yong-An;Hwang, Ki-Chul;Maeng, Lee-So
    • Molecules and Cells
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    • 제38권7호
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    • pp.643-650
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    • 2015
  • The use of conditioned medium from mesenchymal stem cells may be a feasible approach for regeneration of bone defects through secretion of various components of mesenchymal stem cells such as cytokines, chemokines, and growth factors. Mesenchymal stem cells secrete and accumulate multiple factors in conditioned medium under specific physiological conditions. In this study, we investigated whether the conditioned medium collected under hypoxic condition could effectively influence bone regeneration through enhanced migration and adhesion of endogenous mesenchymal stem cells. Cell migration and adhesion abilities were increased through overexpression of intercellular adhesion molecule-1 in hypoxic conditioned medium treated group. Intercellular adhesion molecule-1 was upregulated by microRNA-221 in mesenchymal stem cells because microRNAs are key regulators of various biological functions via gene expression. To investigate the effects in vivo, evaluation of bone regeneration by computed tomography and histological assays revealed that osteogenesis was enhanced in the hypoxic conditioned medium group relative to the other groups. These results suggest that behavioral changes of endogenous mesenchymal stem cells through microRNA-221 targeted-intercellular adhesion molecule-1 expression under hypoxic conditions may be a potential treatment for patients with bone defects.

일부 한국 여성에 있어 칼륨과 단백질의 섭취량에 의한 NEAP(net rate of endogenous noncarbonic acid production)와 골밀도와의 관련성 (The Relation between Net Rate of Endogenous Noncarbonic Acid Production from Diet Potassium and Protein Intakes and Bone Mineral Density in Korean Women)

  • 배윤정;최미경;김미현;김은영;이주연;승정자
    • 한국식품영양과학회지
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    • 제35권9호
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    • pp.1200-1206
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    • 2006
  • 단백질과 칼륨의 섭취량으로 산출한 NEAP와 여성의 골밀도 및 골대사지표와의 관련성을 알아보기 위하여 $18\sim81$세의 여성 276명을 대상으로 설문조사와 식사섭취조사, 요추와 대퇴경부의 골밀도 측정, 소변의 디옥시피리디놀린을 분석한 결과는 다음과 같다. 대상자들의 NEAP 수준은 요추 골밀도(p<0.05)와 유의적인 음의 상관성을 보였고 대퇴경부 골밀도와도 유의적인 수준은 아니었으나 음의 상관성을 보였다. NEAP의 수준에 따라 대상자를 4분위수로 분류하고 연령, 신장, 체중의 차이를 보정하여 골밀도를 비교하였을 때 NEAP 수준이 가장 낮은 군의 요추 및 대퇴경부 골밀도가 가장 높았으나 유의적인 차이를 보이지는 않았다. 또한 단백질의 섭취량에 따른 골밀도의 4분위수 분석결과 단백질의 섭취량이 증가함에 따라 요추 골밀도가 감소하였다(p<0.05). 이상의 연구결과를 통하여 체내에서 알칼리를 생성하는 칼륨의 섭취증가와 체내에서 산을 생성하는 단백질의 섭취감소를 통한 체내 산도의 감소가 여성의 골밀도와 긍정적인 관련성을 나타낼 수 있음이 제시되었다. 따라서 칼슘섭취의 부족문제가 좀처럼 해결되고 있지 않은 우리나라의 식생활에서 골용해와 칼슘의 배설을 줄임으로써 골격건강을 유지할 수 있는 방안으로 단백질의 과잉섭취를 제한하고 체내 알칼리를 형성할 수 있는 무기질이 풍부한 식품의 섭취를 늘일 수 있도록 하는 식사지침의 마련이 필요하다고 생각된다. 또한 본 연구에서는 골밀도에 긍정적인 영향을 미치는 체내 알칼리성 유도 영양소를 칼륨으로만 한정했지만, 마그네슘이나 칼슘 등도 체내 알칼리성에 영향을 미치는 요인이기 때문에 다양한 알칼리성 영양소의 섭취가 골밀도에 미치는 영향에 대한 추후 연구가 요구된다.

Somatic Embryogenesis: Morphogenesis, Physiology, Biochemistry and Molecular Biology

  • Thorpe, Trevor A.
    • 식물조직배양학회지
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    • 제27권4호
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    • pp.245-258
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    • 2000
  • Somatic embryogenesis has become a major tool in the study of plant embryology, as it is possible in culture to manipulate cells of many plant species to produce somatic embryos in a process that is remarkably similar to zygotic embryogenesis. Traditionally, the process has been studied by an examination of the ex vitro factors which influence embryo formation. Later structural, physiological and biochemical approaches have been applied. Host recently, molecular tools are being used. Together, these various approaches are giving valuable information on the process. This article gives an overview of somatic embryogenesis by reviewing information on the morphogenesis, physiology, biochemistry and molecular biology of the process. Topics covered include a brief description of the factors involved in the production of embryogenic cells. Carrot cell suspension is most commonly used, and the development of a high frequency and synchronous system is outlined. At the physiological and biochemical lev-els various topics, including the reactivation of the cell cycle, changes in endogenous growth regulators, amino acid, polyamine, DNA, RNA and protein metabolism, and embryogenic factors in conditioned medium are all discussed. Lastly, recent information on genes and molecular markers of the embryogenic process are outlined. Somatic embryogenesis, the best example of totipotency in plant cells, is not only an important tool in studies in basic biology, but is potentially of equal significance in the micropropagation of economically important plants.

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DEA와 Malmquist 생산성지수를 이용한 우리나라 온라인쇼핑업체의 다기간 경영 효율성 분석 (Evaluating the Multi-Period Management Efficiency of Domestic Online-Shopping Companies)

  • 마진희;자윤호;안영효
    • 유통과학연구
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    • 제13권4호
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    • pp.45-53
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    • 2015
  • Purpose - Online shopping enables consumers to conveniently purchase products irrespective of the time and place. As a result, several online shopping companies have emerged to cater to this growing market and, therefore, the competition among them has become increasingly intense. This paper evaluates the comparative efficiency of online shopping companies for a multi-year period (2009-2013), in order to help online shopping managers identify major drivers for enhancing management efficiency and the subsequent competitiveness. Research design, data, and methodology - The researchers collected the data from 2009 to 2013 from the distribution yearbook. This paper analyzes the marketability (sales figures), profitability (business profits), and management conditions (net profits) of domestic online shopping enterprises by incorporating information on human resources (number of employees) and material resources (total assets and capital). Therefore, the number of employees, total assets, and capital are selected as input variables, and sales figures, business profits, and net profits as the output variables. In this study, Data Envelopment Analysis (DEA) was used to measure the comparative efficiency of domestic online shopping companies. In addition, the Malmquist Productivity Index was used to evaluate the trend of change of Decision Making Units' (DMUs') efficiency for a multi-year period. Results - First, as of 2013, Interpark (2.415) was found to be the most efficient online shopping enterprise, followed by Aladdin Communications (2.117), Hyundai Home shopping (1.867), Home&Shopping (1.176), NS Home shopping (1.170), Commerce Planet (1.126), CJ O Shopping (1.105), Ebay Korea (1.088), and GS Home Shopping (1.051). Second, this study recognizes how the management efficiency has changed for the period 2009-2013. Third, the lesser the capital and employees, the more are the net profits, and the better is the management efficiency of domestic online shopping companies. Lastly, the productivity of such companies is influenced by endogenous factors rather than exogenous factors such as shifts in business environment and technological advances. Conclusions - DHC Korea influenced various distribution channels to reach customers through the Internet. Consequently, this helped in increasing the awareness about its products, in addition to an increase in sales. These achievements can be attributed to the characteristics of online shopping companies. Although it is easy for these companies to suggest goods for one-off purchases, they however have difficulties in retaining customers. Overcoming this challenge can be one of the ways to benchmark a successful case of an efficient company. For example, an online shopping company can attract customers by developing a corresponding mobile application as a convenient way to shop online. Additionally, they can satisfy customers by quick delivery of purchased products, which is possible by building an effective logistics network. Our study indicates that the productivity of an online shopping company was influenced by endogenous factors driven by improvements in managerial practices rather than exogenous factors. Accordingly, online shopping companies should adopt strategies to improve their operational efficiency rather than sales volume-oriented management.

렴瘡에 對한 文獻的 考察 (A literatual study on the Ecthyma)

  • 김희택;오영선;노석선
    • 한방안이비인후피부과학회지
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    • 제10권1호
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    • pp.209-246
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    • 1997
  • In the literatual study on the Ecthyma, the results were as follows. 1. The pathogenic factors of Ecthyma is divided three parts. One is exogenous pathogenic factors which including the wind evil, wind heat and toxic material produced by wetness evil. Another is endogenous pathogenic factors which including the declination of kidney-yang, impairment of the liver and kidney, the lower classes of yin-fire, accumulation of wetness-heat in the spleen asthenia, impairment of the liver and kidney, wetness-heat of three yang, asthenic heat-syndrome of three yin. The other is pathogenic factors neither endogenous nor exogenous which including the food and living, uncontrol sexual excess, anxiety and angry, injury of skin, injury of insects and animals. 2. Five viscera which was concerned with Ecthyma are liver, spleen and kidney. 3. Frequent region of Ecthyma are S-36(足三里) and C-7(陰交). External Ecthyma was rose to wetness-heat of three yang channel that cured easily. Internal Ecthyma was rose to asthenic heat-syndrome of three yin channel that cured hardly. 4. In the frequency of prescription, the most numerous prescription is Bojungikgitang(補中益氣湯) and the next are Kyukgigo(隔紙膏) and Yukmijihwanghwan(六味地滉丸). 5. In the frequency of medicine, the most medicine is Calomelas(輕粉) which included Hydrargyrum(水銀) and the next are Olibanum(乳香) and Resina Commiphorae Myrrhae(沒藥) which regulating vital energy and pain control medicine used that in order to destroy insects and remove polson. 6. In classification of the medical action, medicine of clearing away summer-heat and heat evil and activating blood circulation to dissipate blood stasis used to be very busy which in order to remove the disorder of vital energy for virulent heat-evil. 7. In classification of four characters, the most part is warm medicine, the next are cold and cool medicine and there is a few that is hot medicine. 8. In classification of five tastes, the most numerous tastes are bitter and acrid, the next are sweet, salty and sour tastes. 9. In classification of virulence of medicine, the most part is non-toxic, the next are weakly and deadly poison. 10. In classification of channel distribution, the most is the medicine that belongs to liver channel, the next are the lung, spleen, stomach and kidney channel.

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갑상선암의 예후적 인자와 생존율 (The Prognostic Factors and Survival Rate in Thyroid Carcinoma)

  • 이승재;김상효;백낙환
    • 대한두경부종양학회지
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    • 제9권1호
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    • pp.33-41
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    • 1993
  • A multivariate analysis of the prognostic factors and five year survival rate was carried out on a series of 72 thyroid cancers treated surgically from 1980 to 1987 and followed for 1 to 11 years. The prognosis of the disease was significantly influenced by age at diagnosis, extracapsular invasion, angioinvasion and pathologic type, but the disease was not influenced by sex, lymph node metastasis, and 'risk' category. The overall five year survival rate was 89.7%. Six patients were dead of tumor after surviving for six months to two and half years, and the cause of death was local recurrence in three, lung metastasis in two and bone metastasis in one patient. Five year survival rate in age above fifty, presence of capsule and angioinvasion, follicular carcinoma, and extrathyroidal lesion was significantly shorter than that of patients with age below fifty, absence of capsule and angioinvasion, papillary carcinoma, and intrathyroidal lesion. Patients at low risk or with small carcinomas had long survival over 5 years with only lobectomy. Lymph node dissection was done with a limited type in no jugular metastasis, radical neck disscetion was performed only therapeutically in proved jugular node metastasis. Thyroid hormone was administered for the period of 3 to 5 years to suppress endogenous TSH production.

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