• 보건행정학회지
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• 제30권1호
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• pp.1-3
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• 2020

Coronavirus disease 2019 (COVID-19), which originated in Wuhan, China, is pandemic. It has occurred in more than 170 countries on six continents. In Korea, COVID-19's cases are more than 9,000. The reasons of pandemic COVID-19 are that COVID-19 can spread asymptomatic or early in symptoms although similar reproductive number to severe acute respiratory syndrome coronavirus (SARS), that there are more travelers in China and world than the SARS of 2003, and that the control of COVID-19 was contaminated to political considerations in China, World Health Organization (WHO), and Korea. Emerging infectious diseases such as COVID-19 will occur in the future. To prepare for control of emerging infectious disease, first, the Ministry of Health should be independent from Ministry of Health and Welfare and the department of disease management should be established. Second, experts for making evidence about the emerging infectious diseases should be trained and the plan that is the mobilization of manpower and facilities in large cases will be established. Third, the WHO should enhance its capacity to manage emerging infectious diseases and Korea will support the country of occurred emerging diseases through experts in the analysis of emerging infectious diseases.

• Journal of Preventive Medicine and Public Health
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• 제50권6호
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• pp.411-414
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• 2017

Antimicrobial resistance and emerging infectious diseases, including avian influenza, Ebola virus disease, and Zika virus disease have significantly affected humankind in recent years. In the premodern era, no distinction was made between animal and human medicine. However, as medical science developed, the gap between human and animal science grew deeper. Cooperation among human, animal, and environmental sciences to combat emerging public health threats has become an important issue under the One Health Initiative. Herein, we presented the history of One Health, reviewed current public health threats, and suggested opportunities for the field of public health through better understanding of the One Health paradigm.

• 한국간호교육학회지
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• 제28권4호
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• pp.421-432
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• 2022

Purpose: As coronavirus disease 2019 (COVID-19) and other emerging infectious diseases continue to threaten health security, a strategy is required to increase nursing students' care intention for patients with such diseases. This study aimed to identify factors influencing Korean nursing students' care intentions in regard to patients with emerging infectious diseases. Methods: The care intention, COVID-19 knowledge level, ethical sensitivity, beliefs, attitudes toward the care intention, subjective norms, and perceived behavioral control were investigated using the theory of planned behavior. An online survey was completed from December 2020 to January 2021 by 227 nursing students who had complete a clinical practicum. Descriptive statistics, correlation, and hierarchical regression analyses were conducted on the data. Results: The care intention was higher in men than in women nursing students and in junior than in senior students. Behavioral and normative beliefs, attitude toward the behavior, and perceived behavioral control significantly predicted care intention. Ethical sensitivity increased the predictability of nursing students' care intentions for emerging infectious disease patients. Conclusion: The theory of planned behavior predicted nursing students' care intentions for emerging infectious diseases. Therefore, an experience-based response program on emerging infectious diseases is required for nursing students.

• 한국융합학회논문지
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• 제10권4호
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• pp.285-293
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• 2019

본 연구의 목적은 대학생의 건강증진 생활양식, 신종전염병에 대한 건강신념 및 위생행위 간의 관계를 확인하고자 수행하였다. 서울에 소재한 일개 대학에서 252명 대학생이 건강증진 생활양식, 신종전염병에 대한 건강신념 및 위생행위에 관한 질문을 포함하는 온라인 설문조사에 참여하였다. 연구결과, 첫째, 대학생의 성별과 지각된 건강상태에 따라 건강증진 생활양식에 유의한 차이를 보였고, 신종전염병 예방교육이 필요하다고 응답한 대학생과 그렇지 않은 대학생에서 위생행위에 유의한 차이를 보였다. 둘째, 대학생의 위생행위에 영향을 미치는 요인은 전공, 건강증진 생활양식 및 신종전염병에 대한 건강신념으로 나타났다. 이와 같은 결과를 토대로 대학생을 대상으로 하는 건강관련 교육을 적용함에 있어서 신종전염병에 관한 건강신념을 확립할 수 있는 교육내용을 포함할 필요가 있으며, 신종전염병을 예방할 수 있는 위생행위를 포괄적으로 다루는 프로그램을 개발할 필요가 있다.

• Journal of Preventive Medicine and Public Health
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• 제38권4호
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• pp.373-378
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• 2005

Influenza virus has a unique characteristics of annual epidemics of acute respiratory disease with attack rate of 10%-30% of the population. It is also the classical emerging infectious disease causing global pandemics when new antigenic shift occur. This antigenic shift is the key to its ability to evoke periodic pandemics, and it has caused at least 3 pandemics in 20th century. I reviewed these 3 pandemics in their natural courses and the epidemiology of the recent emerging influenza A viruses, especially the H5 and H7 subtypes. I descr ibed the epidemics of these vi ruses in human population and why we should be prepared to these viruses.

• Journal of Veterinary Science
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• 제24권3호
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• pp.42.1-42.6
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• 2023

Lumpy skin disease (LSD) is one of the most important emerging transboundary diseases. Recently, LSD has emerged in many countries in the northern hemisphere. The LSD virus has a huge genome and is highly resistant to environmental conditions. The virus is also host-specific and large ruminants, such as cattle and domestic water buffalo, are particularly susceptible. In addition, wild ruminants can serve as potential reservoirs for spreading the LSD virus. The emergence might be related to climate change in various regions because LSD is an arthropod-borne infectious disease. This disease causes enormous economic losses, such as leather damage, decreased milk production, abortion, and death in infected ruminants. The economic importance of LSD in the bovine industry has forced countries to develop and implement control strategies against the disease. With the recent global spread and the economic impact, LSD will be discussed intensively. In addition, effective preventive measures are suggested based on the presence or absence of LSD outbreaks.

• Journal of Preventive Medicine and Public Health
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• 제49권1호
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• pp.1-17
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• 2016

The Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea in 2015 has drawn public attention regarding the legal regulation of infectious disease control in Korea. This paper discusses the interpretive and legislative concerns regarding the Infectious Disease Prevention and Control Act, its ordinance and enforcement regulations, as well as public statements from the relevant administrative agency. Future improvements are also proposed.

• 중환자간호학회지
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• 제8권2호
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• pp.66-79
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• 2015

Purpose: This study aimed to derive the elements for effectively improving the management of emerging infectious diseases in the emergency room in large general hospitals. Methods: This research involved an analytic hierarchy process analysis of 10 experienced nurses working in a large general hospital located in the Seoul metropolitan area. The weighted values of the criteria for evaluating the importance of the management elements of patients with emerging infectious diseases in the emergency room of large general hospitals were derived using an analytic hierarchy process survey. Results: The results of the analytic hierarchy process analysis showed that experts considers responsiveness (0.291) as most important with respect to the criteria for the policy for isolation and control of infectious patients. The order of importance of the criteria for the policy for isolation and control of infectious patients were as follows: responsiveness (0.291), economical efficiency (0.257), feasibility (0.242), and sustainability (0.209). Subsequently, the weighted values of the management of the policy elements were determined based on the derived importance of the criteria mentioned above. These were, in order of priority, the construction of communication channels with the government authorities when dealing with emerging infectious diseases (15.9%), the equipment and provision of personal protective equipment to protect nurses from infection and dissemination of material (14.6%), and the operation of the isolation room and patient separation systems (14.1%). Conclusion: This study suggests critical strategies for infection control during a pandemic of emerging infectious disease.

• 임상간호연구
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• 제29권2호
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• pp.175-185
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• 2023

Purpose: The purpose of this study was to investigate the influence of nurses on the nursing intentions in patients with emerging infectious diseases. Methods: Data were collected from 201 nurses with over one year of clinical experience in a general hospital located in Seoul, South Korea. A structured self-report questionnaire was utilized to measure belief factors, core factors, rewards, and nursing professional pride, as well as nursing intentions in patients with emerging infectious diseases. Results: The results revealed that nurses' intentions to provide care for patients with emerging infectious diseases were significantly influenced by perceived behavioral control (β=.26, p<.001), clinical experience (β=-.14, p=.008), behavioral beliefs (β=.31, p=.010), feeling of vocation (β=.29, p=.012) and attitudes toward behaviors (β=.08, p=.034). Conclusion: Enhancing nurses' intentions to provide care for patients with emerging infectious diseases requires the implementation of systemic and educational strategies aimed at strengthening their confidence and beliefs.

• Molecules and Cells
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• 제45권10호
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• pp.702-717
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• 2022

Hepatitis C virus (HCV) infection can lead to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. HCV employs diverse strategies to evade host antiviral innate immune responses to mediate a persistent infection. In the present study, we show that nonstructural protein 5A (NS5A) interacts with an NF-κB inhibitor immunomodulatory kinase, IKKε, and subsequently downregulates beta interferon (IFN-β) promoter activity. We further demonstrate that NS5A inhibits DDX3-mediated IKKε and interferon regulatory factor 3 (IRF3) phosphorylation. We also note that hyperphosphorylation of NS5A mediates protein interplay between NS5A and IKKε, thereby contributing to NS5A mediated modulation of IFN-β signaling. Lastly, NS5A inhibits IKKε-dependent p65 phosphorylation and NF-κB activation. Based on these findings, we propose NS5A as a novel regulator of IFN signaling events, specifically by inhibiting IKKε downstream signaling cascades through its interaction with IKKε. Taken together, these data suggest an additional mechanistic means by which HCV modulates host antiviral innate immune responses to promote persistent viral infection.