• Asian Pacific Journal of Cancer Prevention
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• v.16 no.3
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• pp.1073-1076
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• 2015

Background: To explore the relationship between CXCR4, CD133 co-expression and clinicopathological features as well as prognosis of patients with phase II~III colon cancer. Materials and Methods: Forty-nine paraffin-embedded samples of tumor tissue and epithelial tissue adjacent to cancer were collected from patients with colon cancer undergoing radical surgery in Baotou Cancer Hospital from January, 2010 to June, 2011. CXCR4 and CD133 expression was detected using immunohistochemistry and its relationship with clinicopathological features and the 3-year survival rate was analyzed. Results: In the tumor tissue and colonic epithelial tissue adjacent to cancer, the positive expression rates of CXCR4 were respectively 61.2% (30/49) and 8.16% (4/49), while those of CD133 being 36.7% (18/49) and 6.12% (3/49). CXCR4 and CD133 expression in tumor tissue was not related to patient age, gender, primary focal sites, tumor size, TNM staging, histological type, tumor infiltration depth and presence or absence of lymphatic metastasis, but CXCR4 and CD133 co-expression was associated with TNM staging and lymphatic metastasis. The 3-year survival rate of patients with CXCR4 and CD133 co-expression was 27.3% (3/11), and that of the remainderwas 76.3% (29/38), the difference being significant ($X^2=7.0206$, p=0.0081). Conclusions: CXCR4 and CD133 co-expression may be a risk factor for poor prognosis of patients with stage II~III colon cancer.

• Ocean and Polar Research
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• v.36 no.2
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• pp.165-177
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• 2014

In an effort to investigate the structure and variability of the coastal current in the East Sea, a moored ADCP observation was conducted off Uljin from late May to mid-October 2006. Owing to the transition of season from summer to autumn, the features of the current and wind can be divided into two parts. Until mid-August (Part-I), a southward flow is dominant at all depths with a mean alongshore velocity of 4.2~8.9 cm/s but northward winds are not strong enough to reverse the near-surface current. During Part-II, a strong northward current occurs frequently in the upper layer but winds are predominantly southward including two typhoons that have deep-reaching influence. Profile of mean velocity has three layers with a northward velocity embedded at 12~28 m depth. The near-surface current of Part-II significantly coheres with winds at 4-8 day periods with a phase lag of about 12 hours. The modal structure of the current obtained by EOF analysis is: (1) Mode-1, having 83.6% of total variance, represents the current in the same direction at all depths corresponding to the southward North Korean Cold Current (NKCC). (2) Mode-2 (11.7%) reveals a two-layer structure that can be explained by the northward East Korean Warm Current (EKWC) in the upper layer and NKCC in the lower. (3) Mode-3 (2.6%) has three layers, in which the EKWC is reversed near the surface by opposing winds. This mode is particularly similar to the mean velocity profile of Part-II.

• Journal of Biosystems Engineering
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• v.40 no.3
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• pp.165-177
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• 2015

Purpose: Accurate monitoring of soil strength is a key technology applicable to various precision agricultural practices. Soil strength has been traditionally measured using a cone penetrometer, which is time-consuming and expensive, making it difficult to obtain the spatial data required for precision agriculture. To improve the current, inefficient method of measuring soil strength, our objective was to develop and evaluate an in-situ system that could measure horizontal soil strength in real-time, while moving across a soil bin. Methods: Multiple cone-shape penetrometers were horizontally assembled at the front of a vertical plow blade at intervals of 5 cm. Each penetrometer was directly connected to a load cell, which measured loads of 0-2.54 kN. In order to process the digital signals from every individual transducer concurrently, a microcontroller was embedded into the measurement system. Wireless data communication was used between a data storage device and this real-time horizontal soil strength (RHSS) measurement system travelling at 0.5 m/s through an indoor experimental soil bin. The horizontal soil strength index (HSSI) measured by the developed system was compared with the cone index (CI) measured by a traditional cone penetrometer. Results: The coefficient of determination between the CI and the HSSI at depths of 5 cm and 10 cm ($r^2=0.67$ and 0.88, respectively) were relatively less than those measured below 20 cm ($r^2{\geq}0.93$). Additionally, the measured HSSIs were typically greater than the CIs for a given numbers of compactor operations. For an all-depth regression, the coefficient of determination was 0.94, with a RMSE of 0.23. Conclusions: A HSSI measurement system was evaluated in comparison with the conventional soil strength measurement system, CI. Further study is needed, in the form of field tests, on this real-time measurement and control system, which would be applied to precision agriculture.

• Journal of Korean Society of societal Security
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• v.3 no.1
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• pp.25-32
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• 2010

Detecting rebars in side the concrete structures is one of the important steps in assessing condition of the structure. In order to determine the detection capability of locating rebars inside the concrete, two types of equipments, which use radar system and electromagnetic system each, were tested. Four concrete specimens which have the dimensions of $1,000mm(length){\times}300mm(width)$ with different thickness and diameter of steel bars were applied. A series of testing was achieved after drying in air for 90 days, immersed in water for 3, 24, 48 hour and 28 day. From the experimental outcome, it is shown that error is increased as the diameter of rebar enlarge in case of electromagnetic method. In case of radar method, the detection of embedded rebars in deep is good in the view of reliability. As moisture content increase from 3.6% to 5.5%, the relative permittivity of concrete test specimens show tendency to increase, too. Therefore, it is shown that moisture content is one of the major contributing factors to determine the relative permittivity. And the relative permittivity regression equation is suggested.

• Journal of the Korean Geotechnical Society
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• v.34 no.7
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• pp.29-38
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• 2018

Three-dimensional continuum modeling of dynamic soil-pile-structure interaction embedded in a liquefiable sand was carried out. Finn model which can model liquefaction behavior using effective stress method was adopted to simulate development of pore water pressure according to shear deformation of soil directly in real time. Finn model was incorporated into Non-linear elastic, Mohr-Coulomb plastic model. Calibration of proposed modeling method was performed by comparing the results with those of the centrifuge tests performed by Wilson (1998). Excess pore pressure ratio, pile bending moment, pile head displacement-time history according to depth calculated by numerical analysis agreed reasonably well with the test results. Validation of the proposed modeling method was later performed using another test case, and good agreement between the computed and measured values was observed.

• Journal of Periodontal and Implant Science
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• v.44 no.6
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• pp.280-287
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• 2014

Purpose: The purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling and root planing (SRP) in patients with chronic periodontitis. Methods: The study was conducted from December 2013 to May 2014 at Ewha Womans University Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderate chronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio: SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performed thrice a day for a month by using electric toothbrushes with embedded light-emitting diodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing were assessed before (baseline) and four weeks after (follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacterium nucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcus mutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chain reaction at the same points in time. Results: The clinical parameters improved in both the groups. At the follow-up assessment, PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CAL showed significantly greater changes in the SRP+PT group than in the SRP group (PPD, P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but no significant intergroup differences were noted. Conclusions: Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobial effects is not sufficient. Long-term studies are necessary to develop the most effective PT protocol and compare the effectiveness of PT with and without exogenous photosensitizers.

• Journal of the Korean Geotechnical Society
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• v.21 no.5
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• pp.171-177
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• 2005

Fire in underground space may induce severe structural damage as well as heavy casualties. To protect underground structure and passengers from fire, it is very essential to characterize fire-induced damage on construction materials of underground structures. In this study, the high-temperature furnace was manufactured to evaluate fire-induced damage on underground structure materials. Especially, this study aimed at the evaluation of fire-induced damage on the shield TBM concrete segment. In the fire tests, furnace temperature was set to reach 1,200 degrees at five minutes after Ignition. The temperature of 1,200 degrees was kept during one hour, and the fire was extinguished after two hours elapsed. From the temperature measurement by thermocouples embedded in test specimens, the spatting was estimated to reach approximately 20 cm from the surface exposed to fire. After the fire tests, the alteration of physico-mechanical properties and microstructures of concrete segment was investigated from core specimens. The results showed that apart from spatting, the deterioration depth of the remaining concrete material amounted to approximately 10 cm from the spatting surface.

• Journal of the Korean Geotechnical Society
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• v.28 no.6
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• pp.5-17
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• 2012

The moment responses of electric pole foundations for a railway were investigated using real-scale load tests. Large overturning moments were applied to two circular rigid piles with a 0.75 m diameter and a 2.5 m embedded depth; the circular rigid piles were installed in an actual railway embankment fill. Two different loading directions-toward the fill slope and toward the track -were applied to evaluate the influence of the fill slope on the moment capacities of the foundations. It was found that the failure of the foundations that were constructed according to Korean railway practices exhibited a sudden overturning pattern without any significant pre-failure displacement. The moment capacity toward the fill slope was less than the moment capacity toward the track by 30%. From the test results, the geometry factor (K), which accounted for the reduction of the moment capacity, due to the fill slope, was 0.7. Moment capacities determined from the load tests were compared with those predicted from three existing design methods, and their applicability was discussed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.3C
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• pp.105-111
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• 2012

Bucket foundations, which are used in the foundations of offshore wind turbines, should be able to withstand large amounts of horizontal and moment loads. Tripod bucket foundation, which combines three single buckets, has been used to increase horizontal and moment capacities. This study performed numerical analysis using ABAQUS (2010), to analyze the group effect and the bearing capacity of a tripod bucket in clay. Parametric studies were performed varying the bucket spacing ratio S/D (S=spacing between the centers of the bucket and the tower; D=diameter of the bucket) and depth ratio L/D (L=embedded length of skirt). The applied constitutive models were a linear elastic perfectly plastic model with Tresca yield criteria for normally consolidated clay and an elastic model for buckets. Loading in the vertical, horizontal, and moment directions was simulated with an increase in each movement at a reference point. The bearing behavior and the capacities of a single and a tripod bucket were compared. Capacity evaluation method of the tripod bucket was suggested using the capacity of a single bucket.

• Journal of the Korea Institute of Building Construction
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• v.17 no.3
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• pp.235-243
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• 2017

Carbonation of concrete is being occurred due to interaction of atmospheric carbon dioxide with hydroxides. Reinforce concrete (RC) structure is getting collapse or accident due to corrosion of embedded steel rebar. The maintenance of reinforced concrete structure recently has the attention of researchers regarding durability of structure and its importance day by day is increasing. In order to study the carbonation progress of pre-repaired concrete, present study was carried out to measure the carbonation velocity for different repair materials up to 100% of carbonation. The obtained results have predicted the carbonation progress of repair materials in service condition. These results have been verified by FEM and FDM analysis. As a result, the carbonation depth can be predicted by using the carbonation prediction formula after the repair, and the analytical and the experimental values are almost similar when the initial $Ca(OH)_2$ concentration is assumed to be 40%.