• Journal of the Korean Society of Costume
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• v.55 no.2 s.92
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• pp.45-57
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• 2005

The creative fashion design is the technique which ran be obtained through the structural analysis of the relationship between principle, element-combination and idea-expression. In the research, as the results of theoretical survey of design structure and idea-expression, the structural and subjective designs are classified and defined: a. the structural design is analyzed with the existing examples based on the combinational Idea-expression of the O.C.L method, and b. the subjective design is also analyzed connecting the real examples to Cordon method, Synetic method, Association method, and expansive idea-expression-method obtained by the Experiences of Geometrical Combinations. The research can be summarized as follows: 1. The creative fashion design which emphasizes the geometrical structure utilizes the modification method whirh combines the shapes and constructs extraordinary structural beauty coming from the complex structural principle, that is, emphasis and balance. 2. The creative fashion design which emphasizes specific subjects utilizes the modification method which mimics representative and plastic resemblances and constructs symbolic structural beauty coming from the simple structural principle, that is, material elements.

• Korean Institute of Interior Design Journal
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• v.24 no.4
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• pp.3-13
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• 2015

For last decades, the interests and efforts to enhance healthcare facility users' experience is focused on improving facility environments for healing (Delvin, 2003) and servicescapes in order to meet the users' needs (Becker, 2008; Seunghee, 2011). In the emerging experience economy, customer want experiences and they're willing to pay for the experiences and memories not goods. (Pine, J. & Gillmore, J., 1999). It is important to identify what supports customer experiences and how they perceive the experiences in healthcare environments and it will provide important information for healthcare planners, managers, architects, and interior designers. This study examines the service user experience design elements from a User Experiences design perspective. It focuses on healthcare facilities as user experience elements and build up a conceptual framework that outlines service user experience design elements in healthcare facilities. Literature review and case studies were conducted to build the service user experience design elements according to affordance theory. Findings from this study shows that service user experience design elements were introduced and newly developed which can be categorized into three factors; 1) Functional experiences in the physical environments (safety, accessibility, self-directiveness), 2) emotional expression and cognitive experiences (identifiability/clarity, natural features/pleasant environment, aesthetic elements/playful space, media richness), 3) social relational experiences(closeness, privacy, communication with staff, integrated system). These service user experience design elements will help healthcare facility designers to understand what customer experiences, how they increase the satisfaction, and how they improve facilities for modeling the industry's best practices.

• Journal of Fashion Business
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• v.8 no.6
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• pp.123-136
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• 2004

The purpose of this the end of 20th century fashion about various phenomenon of distopia. This study have the analysis and consideration through the elements and peculiarity of distopia. This study give us the various figures of distopia st fashion as well as the common features of distopia. The study method refers to sundry records, thesis, fashion magazine, publication, the collection works and internet. It is as follows. 'Distopia' prefix to dis of Utopia and means unknown future. Distopia trends towards future negatively. The end of 20th century, it is well brought out various cultures. Movie, novel and pop culture have effect on end of the 20th fashion with a view of distopia. It is the fear and uncertainty of the future. The characters of distopia through the works are divided into formative characteristics and aesthetics meaning. The future fashion of distopia expression mixed and various cultural life, also the mixed of utopia and distopia fashion. Distopia stimulates the designers to the new expression and expose their new areas.

• Proceedings of the Microbiological Society of Korea Conference
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• 2002.10a
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• pp.109-115
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• 2002

Gene therapy is to treat and cure diseases by an introduction of therapeutic genes in defective cells or tissues of human body. Gene delivery system, gene expression system, and therapeutic gene are three core elements for gene therapy. The efficient delivery of therapeutic genes and appropriate gene expression are the crucial issues for therapeutic outcome of gene delivery. Because it can be used in common for the treatment and cure of various diseases, gene delivery system is the most important core element for a successful gene therapy. Viruses are naturally evolved to transfer their genomes into host cells efficiently. This ability has made vectorologists exploit viruses as attractive vehicles for the delivery of therapeutic genes. Viral vectors based on adenovirus (Ad) and adeno-associated virus (AAV) have been often used for gene delivery in laboratory. Ad and AAV vectors derived from human DNA viruses differ greatly in their life cycle, expression level and duration of transgenes, immunogenicity, and vector preparation. Both vectors can be used as effective tools for gene therapy and more recently in functional genomics. Here, the characteristics of Ad and AAV vectors are discussed.

• Genomics & Informatics
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• v.5 no.1
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• pp.10-18
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• 2007

Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor binding sites (TFBSs). These function as the binding regions for transcription factors (TFs) and thereby regulate gene expression. In this context, various analysis tools have been developed. However, they have shortcomings in the combined analysis of expression patterns and significant TFBSs and in the functional analysis of target genes of significantly overrepresented putative regulators. In this study, we present a web-based A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms (FCAnalyzer). This system integrates microarray clustering data with similar expression patterns, and TFBS data in each cluster. FCAnalyzer is designed to perform two independent clustering procedures. The first process clusters gene expression profiles using the K-means clustering method, and the second process clusters predicted TFBSs in the upstream region of previously clustered genes using the hierarchical biclustering method for simultaneous grouping of genes and samples. This system offers retrieved information for predicted TFBSs in each cluster using $Match^{TM}$ in the TRANSFAC database. We used gene ontology term analysis for functional annotation of genes in the same cluster. We also provide the user with a combinatorial TFBS analysis of TFBS pairs. The enrichment of TFBS analysis and GO term analysis is statistically by the calculation of P values based on Fisher’s exact test, hypergeometric distribution and Bonferroni correction. FCAnalyzer is a web-based, user-friendly functional clustering analysis system that facilitates the transcriptional regulatory analysis of co-expressed genes. This system presents the analyses of clustered genes, significant TFBSs, significantly enriched TFBS combinations, their target genes and TFBS-TF pairs.

• Korean Institute of Interior Design Journal
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• v.13 no.5
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• pp.39-47
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• 2004

In modem days when architectural materials have grave impacts on overall design expression, materials for architecture, especially finishing materials have become the most essential elements for the design expression, as architectural space and form have been. This study closely verifies the concept of tensity analyzed in preceding studies by quantifying it through experimentation and questionnaire, and suggests possible alternatives which verified concept of tensity applies into the architectural design. It was examined how architects consider the finishing materials through a questionnaire. With a questionnaire, the possibility of quantificative analysis for tensity is evaluated by SPSS program. Moreover, a questionnaire about the social image that the architectural finishing materials have was also conducted. This questionnaire results In the actual methods to apply quantificated psychological tensity and social images into the architectural design and recommends better plan to select finishing materials for each spacial function and usage, Due to the great influence of social images in design expression, the application mechanism of the tensity should follow the general and individual principles together. With the tensity figure and application of social images we can find more resonable method for material selection.

• International Journal of Advanced Culture Technology
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• v.10 no.3
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• pp.307-312
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• 2022

The commercialization of the fifth generation (5G) mobile systems has quested enabling technologies, such as intelligent reflecting surface (IRS) transmissions, towards the sixth generation (6G) networks. In this paper, we present a bit-error rate (BER) performance analysis on IRS transmissions in 5G non-orthogonal multiple access (NOMA) networks. First, we derive a closed-form expression for the BER of IRS-NOMA transmissions under Rician fading channels. Then, by Monte Carlo simulations, we validate the proposed approximate BER expression, and show numerically that the derived BER expression is in good agreement with Monte Carlo simulations. Furthermore, we also analyze the BER performance of IRS-NOMA networks under Rician fading channels with different numbers of reflecting elements, and demonstrate that the performances improve monotonically as the number of reflecting devices increases.

• BMB Reports
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• v.42 no.7
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• pp.421-426
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• 2009

Glucocorticoids regulate multiple physiological processes such as metabolic homeostasis and immune response. Mouse Pon2 (mPon2) acts as an antioxidant to reduce cellular oxidative stress in cells. In this present study, we investigated the transcriptional regulation of mPon2 by glucocorticoids. In the presence of glucocorticoid analogue dexamethasone, the expression of mPon2 mRNA in cells was increased, whereas the expression was inhibited by a transcription inhibitor actinomycin D. Glucocorticoid receptors bound to the putative glucocorticoid response elements located between -593 bp and -575 bp of the mPon2 promoter. Transcriptional activity was completely blocked when the putative element was mutated. Taken together, these results suggest that the expression of the mPon2 gene is directly regulated by glucocorticoid-glucocorticoid receptor complexes.

• Journal of the Korean Home Economics Association
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• v.48 no.8
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• pp.39-50
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• 2010

This study aimed to identify today's religious fashion motifs as elements for design development by examining the expression modes such as religious motifs in contemporary fashion. Methodologically, the study conducted literature review and empirical analysis of pictures and articles in domestic and foreign fashion collection magazines and other related data available on the internet and analyzed the collections of 1990 through 2009 with a focus on Christianity, Buddhism and Islam. As a result, this study identified two expression modes of religious motifs in the contemporary fashion. The first expression mode was to employ the forms of religious costumes and their associated images. The second one was to take on religious symbols and their associated images.

• Reproductive and Developmental Biology
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• v.33 no.1
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• pp.63-69
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• 2009

In this study we tried to construct a more efficient tetracycline-inducible gene expression system by replacing previous key elements with more advance ones. At the beginning, we substituted PGK (phophoglycerate kinase) promoter for CMV (cytomegalovirus) promoter to control "$rtTA2^sM2$" which has been known for high induction efficiency in response to tetracycline. With this modification, expression of the EGFP marker gene under the induction condition was significantly increased. Next, we replaced "TRE" fragment with a modified version named "TRE-tighf" which has been reported to have higher affinity and specificity to the transactivator by minor base change of the "TRE" DNA fragment sequence. Use of "TRE-tighf" instead of "TRE" resulted in more than 10 fold increment in terms of induction efficiency and significant decrement of background expression in non-inducible condition. By combining PGK promoter and "TRE-tight" fragment, we could upgrade previous tetracycline-inducible system to show more stringent turn on/off gene switch ability and stronger expression of the gene of our interest. Use of this newly developed system must be very helpful to the studies of gene expression, especially to the transgenic animal study in which non-controllable constitutive expression of the transgene has been one of the urgent problems to be solved.