• 한방재활의학과학회지
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• 제19권2호
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• pp.1-25
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• 2009

Objectives : The purpose of this study was to investigate the effects of Yanghyuljanggeungunbo-tang(Yangxuezhuangjinjianbu-tang, YGKT) and electrical acupuncture treatment in spinal cord injury(SCI)-induced rats. Methods : The subjects were divided into 5 groups ; Normal, Control-no treatment after SCI, Experimental I(Exp. I)-taken with YGKT 500 mg/kg $0.5m{\ell}$ daily after SCI. Experimental II(Exp. II)-taken with electrical acupuncture after SCI and Experimental III(Exp. III)-taken with YGKT 500 mg/kg $0.5m{\ell}$ and electrical acupuncture after SCI. After each operation, the present author observed cytological changes, the motor behavior recovery and nerve regeneration by analysis of the motor behavior tests, EMG, hematological(AST, ALT, WBC), histological and immunological changes. Rats were tested by Motor behavior test at 1st, 3rd, 7th, 14th and 21st day. Results : 1. All the experimental groups were improved compared with control group in the motor behavior tests including Tarlov test, Basso-Beattle-Bresnahan locomotor rating scale, modified inclined plane test, open field test, grid walk test and narrow beam test. Especially Exp. III was significantly improved among other groups. 2. In EMG test, H and M wave were significantly increased in Exp. III. 3. All the experimental groups were significantly decreased compared with control group in AST, ALT and WBC. 4. NGF, BDNF and Trk B of spinal cord gray matter in all the experimental groups were increased compared with control group. Especially, Exp. III was more effective. 5. In histological observations, muscle contraction and denaturation of gastrocnemius muscle of all the experimental groups were inhibited. Especially, those of Exp. III was more effective. On the observations of liver and kidney, cell atrophy and apoptosis of all the experimental groups were decreased compared with control group. Especially, those of Exp. III was more effective. Conclusions : It can be suggested that YGKT and electrical acupuncture may improve motor behavior, EMG, hematological, histological and immunological findings in SCI-induced rats. Especially, combination of these two treatments will be somewhat better in spinal nerve recovery and motor function improvement.

• 혜화의학회지
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• 제23권1호
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• pp.157-166
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• 2014

상완골 간부 골절에 동반된 요골신경 손상을 가진 1명의 환자를 대상으로 "내경(內經)"의 독취양명치법(獨取陽明治法)에 따라 침구치료, 약침치료, 물리치료와 한약치료를 병행하였다. 손목관절의 하수 및 근력약화에 대한 치료성적으로 평가하기 위해 완관절의 운동범위와 능동저항검사를 통한 상대적인 지수를 평가하였으며, 요골신경마비로 인한 장악력의 약화정도는 악력측정기를 사용하여 평가하였다. 수지의 비증의 정도는 Numeric Rating Sclae(NRS) 사정법에 따라 평가하였다. 환자는 발병일로부터 약 6주째에 첫 회복징후를 보이기 시작하였으며, 발병이로부터 약 11.5주째에 가벼운 물건에 대한 집게운동이 가능하며 일상생활을 하는데에 큰 지장이 없는 수준으로 회복되었다. 이는 상완골 간부 골절이 동반된 요골신경손상의 자연회복시기보다 빠른 것으로, "내경(內經)"의 독취양명치법(獨取陽明治法)에 따른 한방치료요법이 상완골 골절에 동반된 요골신경손상의 치료에 효과가 있음을 알 수 있었다.

• 대한임상전기생리학회지
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• 제4권1호
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• pp.1-12
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• 2006

This study conducted RIII reflex measurement to examine degree of pain depending on polarity of high voltage pulsed current of primary and secondary hyperalgesia site in hyperalgesia rat by local thermal injury. Hind paw which was injury site was taken as primary hyperalgeisa site, sole which was injury adjacent site was taken as secondary hyperalgesia site, and mechanical pain threshold, thermal pain threshold and root mean square of RIII reflex were measured. This study was conducted with control group I of hyperalgesia rat at hind paw by thermal injury and experimental groups divided into cathodal high voltage treatment group II, anodal high voltage treatment group III and alternate high voltage treatment group IV, applied active electrode of high voltage pulsed current to hind paw directly, placed reference electrode on the sole of injury adjacent site and applied pulse frequency. It measured RIII reflex and obtained the following results: Root mean square of RIII reflex at primary hyperalgeisa site was significantly reduced in group II after 2 days of hyperalgesia. Group II showed significant decrease after 5 and 6 days of hyperalgesia. Root mean square of RIII reflex at secondary hyperalgesia site showed significant reduction in group II after 6 days of hyperalgesia. Consequently it was found that application of high voltage pulsed current of hyperalgesia site reduced RIII reflex at primary hyperalgeisa site and secondary hyperalgesia site by electrical stimuli. Effects by polarity of high voltage pulsed current showed the greatest reduction of pain threshold when cathodal active electrode was used.

• Archives of Reconstructive Microsurgery
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• 제2권1호
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• pp.70-76
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• 1993

The authors analyzed the clinical results of the reconstructive surgery for injured hands and feet due to frostbites and electrical burn with microsurgery in 7 patients, 12 cases at the department of orthopaedic surgery, school of medicine, Kyung Hee university from Jan. 1989 to Jul. 1992, and the results were as foollowings. 1. The age at the time of injury was av 24.6 yrs ranging from 4 to 35 yrs, and all cases were male. 2. The follow up period was av. 24.4 Mo ranging from 12 Mo. to 56 Mo. 3. The causes of injury were frostbite in 9 cases, electrical burn in 2 cases. 4. Initial operative treatment was performed av. 69.3 days ranging from 2 to 210 days. 5. For the reconstructive procedure, scapular free flap was applied in 6 cases, radial forearm flap in 4, dorsalis pedis 1ffap in 1, neurovascular island flap in 1. 6. Among total 12 cases, there were 5 cases(41.7%) of wound infection and 3 cases (25.0%) of partial necrosis of donor flap. 7. In 11 cases(90.1%), the end result was satisfactory. In the analysis of above results the reconstruction with microsurgery is effective procedure for reconstruction of Injured hand and foot due to frostbite and electrical burn.

• Journal of Electrical Engineering and information Science
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• 제3권3호
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• pp.286-291
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• 1998

A remote measurement system for nerve conduction has been developed to aid patients with spinal cord injury by accident. Existing cooperation between rescuers and doctors can be supported through the introduction of multimedia desktop video conferencing. Such facilities provide several advantages over conventional video conferencing. In particular, patients may feel free because they can see a doctor through the video conferencing facilities. This paper describes the system implementation and evaluation. The author considers the network capability and image data handling, and introduces a method a transmit image data for this system.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1993년도 춘계학술대회
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• pp.120-122
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• 1993

This paper describes an improved FES system to restore paralyzed extremities in spinal cord injury patients. For composing stimulus pattern which is suitable for each muscle, electrical stimulus pattern creating system is also developed by using IBM-PC. In the improved portable FES system using V40 microprocessor, muscle fatigue can be decreased by selecting the stimulus frequency which is proper to the response characteristics of each muscle. Driving softwares for the portable FES system and the stimulus pattern creating system are programmed with assembler and C language. A multichnnel portable FES system is designed to minimize the sire and weight using a D/A converter and 32 channel multiplexer.

• The Korean Journal of Pain
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• 제19권1호
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• pp.33-44
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• 2006

Background: Peripheral nerve injury leads to neuropathic pain, including mechanical hyperalgesia (MH). Nerve discharges produced by an injury to the primary afferents cause the release of glutamate from both central and peripheral terminals. While the role of centrally released glutamate in MH has been well studied, relatively little is known about its peripheral role. This study was carried out to determine if the peripherally conducting nerve impulses and peripheral glutamate receptors contribute to the generation of neuropathic pain. Methods: Rats that had previously received a left L5 dorsal rhizotomy were subjected to a spinal nerve lesion (SNL) or brief electrical stimulation (ES, 4 Hz pulses for 5 min) of the left L5 spinal nerve. The paw withdrawal threshold (PWT) to von Frey filaments was measured. The effects of an intraplantar (i.pl.) injection of a glutamate receptor (GluR) antagonist or agonist on the changes in the SNL- or ES-produced PWT was investigated. Results: SNL produced MH, as evidenced by decrease in the PWT, which lasted for more than 42 days. ES also produced MH lasting for 7 days. MK-801 (NMDAR antagonist), DL-AP3 (group-I mGluR antagonist), and APDC (group-II mGluR agonist) delayed the onset of MH when an i.pl. injection was given before SNL. The same application blocked the onset of ES-induced MH. NBQX (AMPA receptor antagonist) had no effect on either the SNL- or ES-induced onset of MH. When drugs were given after SNL or ES, MK-801 reversed the MH, whereas NBQX, DL-AP3, and APDC had no effect. Conclusions: Peripherally conducting impulses play an important role in the generation of neuropathic pain, which is mediated by the peripheral glutamate receptors.

• 대한물리의학회지
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• 제5권3호
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• pp.341-350
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• 2010

Purpose : To provide information and data about the physical therapy service for planning future Olympic and other mass gatherings. Methods : To document the injuries sustained during the 2008 Beijing Olympic Games in a sample of patients visiting the physical therapy department of the Korean Olympic Committee. Athletes visited the physical therapy department in 2008 Beijing Olympic Korean delegation from 1 August through 22 August. Results : The sex ratio of athletes who visited physical therapy room was male 27.5%, female 72.5% and that number of case sports were higher Handball (26.2%), hockey (15.8%), archery (10.4%). The most prevalent injury of body parts was shoulder (15.1%), followed by the lumbar(14.2%), and the cervical spine (10.5%). Treatment modality had manual therapy(891), electrical therapy (584), ultrasound (461) and the number of taping were handball (47.8%), hocky (23.8%), judo (8.2%). Ankle (31.4%) was the most body parts of taping. Conclusion : Physical therapy in sport as a professional sports event to get their players to injury prevention and treatment. These results can be of help to optimize the strategies to prevent injuries and to treatment the injured athletes.

• Journal of Korean Neurosurgical Society
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• 제54권4호
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• pp.359-362
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• 2013

Chronic hypoventilation due to injury to the brain stem respiratory center or high cervical cord (above the C3 level) can result in dependence to prolonged mechanical ventilation with tracheostomy, frequent nosocomial pneumonia, and prolonged hospitalization. Diaphragm pacing through electrical stimulation of the phrenic nerve is an established treatment for central hypoventilation syndrome. We performed chronic phrenic nerve stimulation for diaphragm pacing with the spinal cord stimulator for pain control in a quadriplegic patient with central apnea due to complete spinal cord injury at the level of C2 from cervical epidural hematoma. After diaphragmatic pacing, the patient who was completely dependent on the mechanical ventilator could ambulate up to three hours every day without aid of mechanical ventilation during the 12 months of follow-up. Diaphragm pacing through unilateral phrenic nerve stimulation with spinal cord stimulator was feasible in an apneic patient with complete quadriplegia who was completely dependent on mechanical ventilation. Diaphragm pacing with the spinal cord stimulator is feasible and effective for the treatment of the central hypoventilation syndrome.

• 전기학회논문지
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• 제58권6호
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• pp.1180-1185
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• 2009

Spasticity is a velocity-dependent stretch reflex disorder of the body motor system developing after the injury of the central nervous system, in which certain muscles are continuously contracted involuntarily. Conventional methods such as the modified Ashworth scale, Spasm frequency scale, pendulum test and isokinetic dynamometer had some disadvantages: limitation in discriminating the increase of resistance, immovable and expensive device, not enough study parameters. Therefore, it is necessary to introduce clinically more useful instrument, which can produce objective data and are more convenient on spasticity measurement. Spasticity measuring methods were reviewed and a new measuring instrument was designed and introduced. The new measuring system is a portable spasticity-measurement system, which encompass various scopes of spasticity-related human signals such as electrophysiologic, kinematic and biomechanical data. Our device was designed in order to measure the joint angle, angular velocity, electromyographic signals and force. We suggest that this new system can diagnose the spasticity of the muscles, objectively.