• Maxillofacial Plastic and Reconstructive Surgery
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• 제32권1호
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• pp.68-71
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• 2010

Facial nerve schwannomas (FNSs) are usually painless, slow-growing, and without specific symptoms, so that early diagnosis may be difficult. They are particularly liable to being misdiagnosed as parotid gland origin benign tumor before surgery, which can lead to unnecessary parotidectomy or unexpected facial nerve injury. To prevent these complications, it is important that the correct diagnosis is performed at least in intraoperative time. When an adhesion between the mass and the facial nerve is exist or when electrical stimulation of the mass triggers facial movement, FNS is highly suggested diagnosis. In such cases, frozen section analysis should always be performed. In this case, the pre-operative diagnosis from clinical examination and MRI was pleomorphic adenoma. However, intraoperative features led us to suspect that the mass originated from facial nerves, and intraoperative frozen section analysis yielded results consistent with a schwannoma. Based on this intraoperative diagnosis, we carried out a successful conservative treatment with preservation of facial nerve.

• 한국멀티미디어학회논문지
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• 제20권10호
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• pp.1678-1688
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• 2017

Infiltration is one of detrimental problems occurring in nursing or medical settings. Early detection of infiltration is essential to minimize the risk of injury from infiltration. To perform a preliminary study on the point of care and automated infiltration detection system, bioelectrical impedance was investigated using bioelectrical impedance analyzer. We would like to report experimental results that allow impedance parameters to effectively distinguish infiltration. Electrodes were attached to both sides of the transparent dressing on the fusion site where IV solution was being infused. Then, impedance parameters before and after infiltration were measured as a function of time and frequency. The experimental results are as follows. After infiltration was intentionally induced by puncturing the vein wall with a needle, the resistance gradually decreased with time. That is, when an alternating current having a frequency of 20 kHz was applied to the electrodes, the resistance gradually decreased with time, reflecting the accumulation of IV solution in the extracellular fluid since the current could not pass through the cell membrane. Impedance parameters and equivalent circuit model for human cell were used to examine the mechanism of current flow before and after infiltration, which could be used for early detection of infiltration.

• 대한한의학회지
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• 제26권3호
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• pp.239-248
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• 2005

Objectives : Electroacupuncture (EA)-induced analgesia has been known to be mediated through the activation of opioid, noradrenergic and serotonergic receptors. However, little study on serotonergic mechanism has been performed in an animal model of chronic pain. The present study was designed to elucidate the type of serotonergic receptors responsible for EA analgesia in the chronic pain model. Methods : In rats with complete Freund's: adjuvant-induced inflammation and spinal nerve injury, spinal wide dynamic range (WDR) cell responses to graded electrical stimulation of afferent C fiber were recorded before and after spinal application of selective 5-hydroxytryptamine (5-HT) receptor antagonists. EA stimulation (2Hz, 0.5msec, 3mA) was applied to the contralateral Zusanli point for 30 min. Results : In both models of chronic pain, WDR cell responses were greatly inhibited after EA stimulation. EA-induced inhibition of WDR celt responses was significantly attenuated by spinal application of non-selective 5-HT receptor antagonist, dihydroergocristine Of 5-HT receptor antagonists tested, 5-HT1A (WAY 100635) and 5-HT2 (LY53857) receptor antagonists strongly reduced an ability of EA stimulation to inhibit WDR cell responses. However, 5-HT1B (GR55562) and 5-HT3 (LY278584) receptor antagonists also had weak but significant blocking action on EA-induced inhibitory effect on chronic pain. Conclusions : Dorsal hem cell responses, afferent C fiber stimulation, chronic pain, electroacupuncture, serotonergic receptors.

• The Korean Journal of Pain
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• 제9권1호
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• pp.26-38
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• 1996

In a normal state, sympathetic efferent activity does not elicit discharges of sensory neurons, whereas it becomes associated with and excites sensory neurons in a pathophysiological state such as injury to a peripheral nerve. Although this sympathetic-sensory interaction is reportedly adrenergic, involved subtypes of adrenoreceptors are not yet clearly revealed. The purpose of this study was to determine which adrenorceptor subtypes were involved in sympathetic-sensory interaction that was developed in rats with an experimental peripheral neuropathy. Using rats that received a tight ligation of one or two of L4-L6 spinal nerves 10~15 days previously, a recording was made from afferent fibers in microfilaments teased from the dorsal root that was in continuity with the ligated spinal nerve. Electrical stimulation of sympathetic preganglionic fibers in T13 or L1 ventral root (50 Hz, 2-5 mA. 0.5 ms pulse duration, 10 sec) was made to see if the activity of recorded afferents was modulated. About half of afferents showing spontaneous discharges responded to sympathetic stimulation, and had the conduction velocities in the A-fiber range. Most of the sympathetically induced afferent responses were excitation. This sympathetically induced excitation occurred in the dorsal root ganglion (DRG), and was blocked by yohimbine (${\alpha}_2$ blocker), neither by propranolol ($\beta$ blocker) not by prazosine (${\alpha}_1$ blocker). The results suggest that after spinal nerve ligation, sympathetic efferents interact with sensory neurons having A-fiber axons in DRG where adrenaline released from sympathetic nerve endings excites the activity of sensory neurons by acting on 2-adrenoreceptors. This 2-adrenoreceptor mediated excitation of sensory neurons may account for sympathetic involvement in neuropathic pain.

• 동의생리병리학회지
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• 제21권2호
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• pp.432-437
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• 2007

Reactive oxygen species (ROS) are toxic agents that may be involved in various neurodegenerative diseases. Recent studies indicate that ROS are also involved in persistent pain through a spinal mechanism. In the present study, whole cell patch clamp recordings were carried out on substantia gelatinosa (SG) neurons in spinal cord slice of neonatal rats to investigate the effects of ROS on neuronal excitability and excitatory synaptic transmission. In current clamp condition, tert-buthyl hydroperoxide (t-BuOOH), an ROS donor, induced a electrical hyperexcitability during t-BuOOH wash-out followed by a brief inhibition of excitability in SG neurons. Application of t-BuOOH depolarized membrane potential of SG neurons and increased the neuronal firing frequencies evoked by depolarizing current pulses. Phenyl-N-tert-buthylnitrone (PBN), an ROS scavenger, antagonized t-BuOOH induced hyperexcitability. IN voltage clamp conditions, t-BuOOH increased the frequency and amplitude of spontaneous excitatory postsynaptic currents (sEPSCs). In order to determine the site of action of t-BuOOH, miniature excitatory postsynaptic currents (mEPSCs) were recorded. t-BuOOH increased the frequency and amplitude of mEPSCs, indicating that it may modulate the excitability of the SG neurons via pre- and postsynaptic actions. These data suggest that ROS generated by peripheral nerve injury can induce central sensitization in spinal cord.

• Korean Journal of Acupuncture
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• 제30권1호
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• pp.47-55
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• 2013

Objectives : The purpose of this study was to determine whether electroacupuncture(EA) is effective in reducing pain on the severe ankle sprain classified as grade 3 in rats. Methods : The severe(grade 3) ankle sprain model was induced surgically by ankle ligament injury(the anterior talofibular, the calcaneofibular and the posterior talofibular) in the Sprague-Dawley rats(180~250 g). The effects of EA on weight bearing forces(WBR) of the affected foot were examined in a rat model of ankle sprain. EA was applied to either SI6, ST37, GB34, GB39 or GB42 acupoints by trains of electrical pulses(2 Hz, 1 ms pulse width, 2 mA intensity) for 15 min. Results : Cutting of the lateral ankle ligament complex produced the severe ankle sprain symptoms as grade 3. EA of the contralateral SI6 resulted in more analgesic effect than one of ipsilateral SI6 even though there was significant effect. EA of the ipsilateral GB34 and GB39 produced potent analgesic effects on the surgical ankle sprained pain behaviors. However, there were no significant analgesic effects in the contralateral GB34 and GB39 EA groups. In addition, both side of ST37 and GB42 did not result in analgesic effect on the surgical ankle sprained rat. Conclusions : The data suggest that EA induced analgesia shows point specificity on the severe ankle sprained pain model classified as grade 3.

• 센서학회지
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• 제10권1호
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• pp.33-41
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• 2001

와이어 로프는 무거운 중량을 안전하게 운반하거나 기계적인 에너지를 빠르게 전송하는 곳과 같은 산업응용 분야에 광범위하게 사용되어 왔다. 특히, 운전 중 엘리베이터의 와이어 로프가 파손되면 큰 재산 상 손실과 주변 인명의 심각한 상해를 초래할 수 있다. 따라서, 와이어 로프의 정기적인 검사는 매우 중요하다. 와이어 로프의 고장 검출은 로프의 구조, 특성, 결함 특성, 검출방법과 신호처리 방법에 대한 기본적인 이해가 요구된다. 이 연구에서는 엘리베이터에 노화된 와이어 로프에 대한 마모, 단선, 부식과 형붕괴와 같은 결함을 검출하기 위하여, Hall 센서를 결합한 새로운 결함 검출시스템의 개발에 대하여 다룬다. 휴대용 계측기로서 검출기를 사용하기 위하여, Hall 센서를 가진 센싱 부분과 아날로그 신호처리 및 프로그램의 제작에 대한 몇 가지 특성들이 서술되었다. 제작된 검출시스템에 대한 실험과 실장시험 결과 역시 제시되었다. 그 결과, 검출시스템은 사용 중인 노화된 와이어 로프의 결함을 검출하는데 양호한 효율성을 갖는다는 것을 확인하였다.

• 전기전자학회논문지
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• 제23권1호
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• pp.74-79
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• 2019

인구 고령화와 웰빙 열풍으로 인해 건강관리 욕구가 증가하면서 피트니스에 대한 관심은 점점 더 높아지고 있다. 사람들은 운동을 하기 위해 헬스장을 가지만, 많은 이들이 운동하는 방법을 몰라 운동 순서나 운동 자세를 틀리게 하는 경우가 많다. 이러면 운동 효과도 미비할 뿐만 아니라 부상의 위험도 커진다. 본 논문에서는 스마트 거울 앞에서 영상을 보며 혼자서 운동을 따라 할 수 있고 운동 자세가 잘못되었을 경우 실시간으로 틀린 곳을 확인시켜주는 스마트 거울을 활용한 피트니스 시스템의 개발 내용에 대해 기술한다. 이 시스템을 사용함으로써 사람들은 혼자서도 트레이너의 도움 없이 바른 자세로 운동을 할 수 있게 될 것이며, 이로 인해 그룹 또는 개인 트레이너를 기다려야 하는 시간이나 비용의 제약에 얽매이지 않고 운동을 할 수 있게 될 것이다.

• 한국컴퓨터정보학회논문지
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• 제27권2호
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• pp.187-194
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• 2022

척수장애인들에게 있어 신체활동 및 운동을 장려함으로써 건강 결과에 긍정적인 영향을 미칠 수 있도록 하는 것이 중요하다. 현재 증거에 따르면 IT기반으로 하는 근력 및 근지구력, 심폐 운동, 전기 자극 운동과 로봇 운동 등 모두 체력 구성 요소를 개선하고 2차 건강 합병증의 위험을 줄이며 만성 신체 장애가 있는 사람들의 전반적인 건강에 긍정적인 영향을 미칠 수 있다. 근력 및 근지구력을 증진하기 위해서는 운동 빈도는 주 2회, 3세트 실시하도록 하며 근력의 증진을 위해서는 < 5 Reps으로, 일반적인 강도는 6~15회 반복하도록 하며, 근지구력을 향상시키기 위해서는 15~30회 반복하도록 한다. 심폐 능력의 향상을 위해서는 주 3-5회, 20~60분, 최고심박수의 50~80%로 실시하도록 하였다. 따라서 IT 기반의 다양한 운동 이점을 실현하고 전문 장비, 시설 및 트레이너에 대한 접근을 위한 더 높은 자원 투자가 필요하다.

• 대한두경부종양학회지
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• 제9권1호
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• pp.3-9
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• 1993

저자들은 뉴질랜드산 흰 가토의 대퇴부에 총 대퇴동맥의 분지를 영양혈관으로 하는 비복근을 이용한 유경 근피판을 만든 후에 영양혈관을 차단 직전과 12시간 동안의 허혈 기간을 가진 후 이 영양혈관으로 생리 식염수로 관류하여 씻어낸 대조군과 urokinase로 관류한 비교군 I, 최근 개발된 인체의 장기 이식시 사용되는 장기(organ) 보존용제인 UW용액을 이용한 비교군 II, UW용액과 pentoxifylline용액으로 관류한 비교군 III에서 재관류 12시간 후에 허혈 및 괴사 정도를 육안적인 관찰과 근육의 전기 자극 검사, TTC 염색, Wet/Dry 무게비 등으로 비교 분석하여 다음과 같은 결과를 얻었다. 육안적 소견상 대조군과 urokinase 사용군에 비해 비교군 II와 III에서 괴사가 적었으며(p<0.05) 근육 조직의 전기 자극 심사에서도 대조군과 비교군 I 은 각각 $1.76{\pm}1.01,\;2.36{\pm}\1.02$로 차이가 없었으나 비교군 II와 III에서 각각 $3.54{\pm}0.93,\;3.49{\pm}1.37gm/mm^2$으로서 대조군에 비해 근육의 강직도가 의의있게 강하게 나타났다(p<0.05). 그리고 TTC 염색에서 대조군의 7례에서 허혈성 괴사 소견이 보였고 비교군 I도 3례에서 허혈성 괴사 소견이 있었으나 비교군 II과 III에서는 허혈성 괴사가 없었으며(p<0.05) 근피판의 wet/dry 무게비에서 대조군과 비교군 I은 각각 $4.55{\pm}0.37,\;4.33{\pm}0.36$으로 차이가 없었으나 비교군 II와 III는 각각 $3.84{\pm}0.29,\;3.75{\pm}0.48$로 대조군과 비교군 I에 비해 부종이 적음을 나타내었다(p<0.05).