• Journal of Veterinary Clinics
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• v.18 no.2
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• pp.167-169
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• 2001

A 10-year-old castrated male Siba dog was presented for signs referable to pleural effusion associated with neoplasm of the thoracic cavity. The pleural effusion fluid consisted of blood and tumor cells by thoracocentesis. Histopathological examination of the sedimentary tumor cells revealed malignant mesothelioma. Intracavitary carboplatin was administered at 300 mg/$m^2$ every 5 weeks for 3 treatment and pleural effusion was disappeared after 3 treatments. The dog had recurrence of pleural effusion at 515 days but intracavitary carboplatin chemotherapy had no effect. It would be thought that the intracavitary carboplatin treatment was quite a useful method to control a canine malignant mesothelioma with minimal toxicity.

• Korean Journal of Veterinary Research
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• v.58 no.2
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• pp.115-118
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• 2018

A 13-year-old spayed female Miniature Schnauzer was presented with complaints of intermittent syncope. Pericardial effusion was confirmed based on the physical examination, thoracic radiographs and echocardiography. Subsequently, prompt pericardiocentesis was performed. Clinical abnormalities were immediately improved after pericardiocentesis. However, the clinical signs associated with acute collapse recurred. After the second pericardiocentesis, thoracic radiographs revealed pleural effusion, and the clinical signs resolved rapidly. The dog underwent pleural aspiration. Analysis of pleural fluid revealed almost similar features as the previous pericardial fluid. It was possible that a pericardial-pleural fistula was created during the pericardiocentesis. The pericardial and pleural effusion disappeared after the procedures.

• Journal of Sasang Constitutional Medicine
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• v.23 no.1
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• pp.125-131
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• 2011

1. Objectives: This purpose of this case is to report that a soeumin patient diagnosed as pleural effusion was treated with Sibimiguanjung-tang and then her symptoms and result of chest X-ray and R-lab improved 2. Methods: We diagnosed the patient as Soeumin-Taeum-byung(少陰人太陰病). So we treated her with Sibimiguanjung-tang 3. Results: After we treated the patient with Sibimiguanjung-tang, her symptoms and result of chest X-ray and R-lab improved 4. Conclusions: This case study show an efficient result of using Sibimiguanjung-tang in Soeumin diagnosed to pleural effusion.

• Journal of the Korean Society of Visualization
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• v.20 no.2
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• pp.28-37
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• 2022

Flow characteristics of jet impingement over concave hemispherical surface with effusion cooling holes is relatively more complex than that of a flat surface, so the experimental validation for computational fluid dynamics (CFD) results is important. In this study, experimental results were compared with simulation results obtained by assuming different turbulence models. The vortex was observed in the region between the central jets where the recirculation structure appeared. The different patterns of vorticity distributions were observed for each turbulence models due to different interaction of the injected jet flow. Among them, the transition k-kl-ω model predicted similarly not only the jet potential core region with higher velocity, but also the recirculation region between the central jets. From the validation, it may be helpful to accurately predict heat and mass transfer in jet impingement/effusion hole system.

• Proceedings of the KSME Conference
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• 2001.06d
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• pp.489-496
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• 2001

Two perforated plates are used to investigate local heat/mass transfer characteristics in an impingement/effusion cooling system. A naphthalene sublimation method is conducted to determine the local heat/mass transfer coefficients on the upward facing surface of the effusion plate. The two plates are placed in parallel position with gap distances of 1, 2, 4 and 6 times of effusion hole diameter. The effects of hole arrangements of the plates are studied for staggered, square, and hexagonal arrays. The experiments are conducted at Reynolds number of 10,000 based on the effusion hole diameter. The results show that the smaller hole size in the staggered array has the higher transfer coefficients on the stagnation region due to the formation of higher momentum flows through the impingement holes. In the square array, heat/mass transfer on the target plate is more uniform as the number of impingement holes increases. High and uniform heat/mass transfer coefficients are obtained in the hexagonal array.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.26 no.1
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• pp.101-109
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• 2002

Two perforated plates are used to investigate local heat/mass transfer characteristics in an impingement/effusion cooling system. A naphthalene sublimation method is conducted to determine the local heat/mass transfer coefficients on the upward facing surface of the effusion plate. Two plates are placed in parallel position with gap distances of 1, 2, 4 and 6 times of effusion hole diameter. The effects of hole arrangements of the plates are studied fur staggered, square, and hexagonal arrays. The experiments are conducted at Reynolds number of 10,000 based on the effusion hole diameter. The results show that the smaller hole size in the staggered array has the higher transfer coefficients on the stagnation region due to the formation of higher momentum flows through the impingement holes. In the square array, heat/mass transfer on the target plate is more uniform as the number of impingement holes increases. High and uniform heat/mass transfer coefficients are obtained for the hexagonal array.

• Tuberculosis and Respiratory Diseases
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• v.57 no.2
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• pp.132-137
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• 2004

Background : The measurement of adenosine deaminase(ADA) level in pleural fluid is useful in the diagnosis of tuberculous(TB) pleural effusion. However, ADA is also elevated in other diseases such as malignancy, bacterial infections, empyema, and collagen vascular disease, ADA alone has limited value. The object of this study is to determine diagnostic usefulness of the combined use of ADA value with lymphocyte/neutrophil ratio(L/N ratio) rather than the use of ADA alone. Method : We evaluated 198 patients(age=$55.9{\pm}12.9$, M/F=2.7:1) with pleural effusion who had admitted in Gyeong-sang National University Hospital from Jan. 1999 to Dec. 2001. retrospectively. Patients were divided into four diagnostic groups: TB pleural effusion(n=91), parapneumonic effusion(n=65), malignant effusion(n=21), and transudative effusion(n=13). The ADA level, differential cell count, biochemistry, cytology, and microbiology of each diagnostic groups were evaluated. The sensitivity, specificity, negative predictive value(npv), positive predictive value(ppv) and efficiency were calculated at each ADA values and combined ADA value with various L/N ratios. Results : The ADA level in TB pleural effusion was significantly higher than that of parapneumonic effusion, malignant pleural effusion, and transudative effusion(p<0.05). Sensitivity, specificity, ppv, npv and efficiency at $ADA{\geqq}50$ IU/L in the diagnosis of TB pleural effusion were 89.0%, 82.2%, 81.0%, 89.8% and 85.5% respectively. When $ADA{\geqq}50$ IU/L was combined with lymphocyte/neutrophil $ratio{\geqq}0.75$, sensitivity, specificity, ppv, npv, and efficiency were 83.5%, 96.3%, 95.0%, 87.9% and 90.5% respectively. Specificity, ppv and efficiency were increased with combination of ADA value and L/N ratio. Conclusion : Combination of ADA value and L/N ratio in pleural effusion is more useful than ADA value alone in the diagnosis of TB pleural effusion.

• Clinical and Experimental Pediatrics
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• v.48 no.5
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• pp.523-526
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• 2005

Purpose : Hypoalbuminemia is a rare cause of pleural effusion. The relationship between the severity of hypoalbuminemia and the clinical course of pleural effusion is unclear. The aim of this study was to evaluate the change of clinical course according to the severity of hypoalbuminemia due to pleural effusion in children. Methods : A total of 96 patients admitted to Pusan National University Hospital with pleural effusion from August 1998 to August 2004 were studied retrospectively. The 79 patients who had only infectious causes were evaluated according to their albumin levels. They were divided into the two groups : group 1 had serum albumin levels of ${\leq}2.5g/dL$; group 2 : >2.5 g/dL. The clinical courses of each group were compared. Results : The nature of pleural effusion was transudates in seven cases and exudates in 89 cases. The most commom causes of transudates were renal failure(four cases) and the most common causes of exudates were parapneumonic effusion(58 cases). There was no statistical significance in mean ages, BUN, creatinine, potassium, bilirubin and WBC in each group. Four patient in group 1 and 26 patients in group 2 improved after medication of antibiotics or anti-tuberculosis agents only. Fourteen patients in group 1 and 26 patients in group 2 improved after thoracostomy with use of antibiotics. Eight patients in group 1 and one patient in group 2 had ventilator care with use of antibiotics therapy. Conclusion : Children who were diagnosed as pleural effusion with low serum albumin levels on admission had poorer prognoses than those with normal levels. We conclude that lower serum albumin level on admission is an important prognosis factor in a patient with pleural effusion.

• Tuberculosis and Respiratory Diseases
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• v.76 no.1
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• pp.15-22
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• 2014

Background: Apoptosis plays a role in the development of pleural effusion. Caspase-cleaved cytokeratin 18, a marker for epithelial cell apoptosis, was evaluated in pleural effusion. Methods: A total of 79 patients with pleural effusion were enrolled. The underlying causes were lung cancer (n=24), parapneumonic effusion (n=15), tuberculous effusion (n=28), and transudates (n=12). The levels of M30, an epitope of caspase-cleaved cytokeratin 18, were measured in blood and pleural fluids using enzyme-linked immunosorbent assay along with routine cellular and biochemical parameters. The expression of M30 was evaluated in the pleural tissues using immunohistochemistry for M30. Results: The M30 levels in pleural fluid were significantly higher in patients with tuberculosis ($2,632.1{\pm}1,467.3U/mL$) than in patients with lung cancer ($956.5{\pm}618.5U/mL$), parapneumonic effusion ($689.9{\pm}413.6U/mL$), and transudates ($273.6{\pm}144.5U/mL$; all p<0.01). The serum levels were not significantly different among the disease groups. Based on receiver operating characteristics analysis, the area under the curve of M30 for differentiating tuberculous pleural effusion from all other effusions was 0.93. In the immunohistochemical analysis of M30, all pathologic types of cancer cells showed moderate to high expression, and the epithelioid cells in granulomas showed high expression in tuberculous pleural tissues. Conclusion: Caspase-cleaved cytokeratin 18 was most prominently observed in tuberculous pleural effusion and showed utility as a clinical marker. The main source of M30 was found to be the epithelioid cells of granulomas in tuberculous pleural tissues.

• The Journal of Internal Korean Medicine
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• v.35 no.3
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• pp.366-372
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• 2014

Objectives: This is a report of a case of a stage IV non-small-cell lung cancer (NSCLC) patient whose malignant pleural effusion & respiratory symptoms have been relieved with Korean medicinal prescription, modified Yieum-jeon. Methods: A 56-year-old male diagnosed with stage IV NSCLC suffering malignant pleural effusion with complaints of cough, sputum, bilateral leg edema, dysphagia, post neck and left scapular pain was treated with modified Yieum-jeon and acupuncture during 16days. After treatment, blood lab and chest X-ray were used to follow the condition of malignant pleural effusion & pulmonary symptoms. Results: Malignant pleural effusion and pulmonary symptoms were improved with modified Yieum-jeon intake without any related adverse side effects. Conclusions: This study suggests Yieum-jeon may play a positive role in improving the malignant pleural effusion symptoms in advanced lung cancer cases.