• 제목/요약/키워드: efficacy rate

검색결과 1,839건 처리시간 0.031초

농작업재해의 원인구명 및 코호트 구축방안 (Cohort Study for Investigation of the Causes in Agricultural Injuries and Diseases)

  • 임현술
    • 농촌의학ㆍ지역보건
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    • 제31권2호
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    • pp.119-144
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    • 2006
  • The Korea rural health study, a large prospective cohort study, the objectives of this study are exploration for potential causes of agricultural injuries and diseases among farmers. Current medical research suggests that they may have higher rates of some traumatic injuries, pesticide poisoning, infectious diseases, musculoskeletal diseases, asthma and other respiratory diseases. This study is designed to identify occupational, lifestyle, and environmental factors of workplace that may affect the rate of diseases in farming population. Round 1, initial cohort recruitment, will begin in 2006 and conclude in 2009. Round 2, follow-up will begin in 2010 and conclude in 2014. Approximately 54,000 persons will be selected to study population. Nested case-control studies and case-crossover studies will be conducted for getting to the bottom of agriculture-related diseases. Recruitment and follow-up are conducted in collaboration with multi-centers. As data on the exposures and health outcomes of this study population are collected and analyzed in 2014. This study will be evaluated by public health experts for effort, achievement, adequacy of performance, efficacy, process of study and so on. The author expects that this cohort study may reduce agricultural injuries and diseases and will provide information that agricultural workers can use in making decisions about their health. Also, this study will be significant basis for strengthening the competitiveness of agriculture in Korea.

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Biological Control of Alternaria Fruit Rot of Chili by Trichoderma Species under Field Conditions

  • Begum, Most. Ferdousi;Rahman, M.A.;Alam, M. Firoz
    • Mycobiology
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    • 제38권2호
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    • pp.113-117
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    • 2010
  • Trichoderma strains were evaluated under field conditions to assay their efficacy in suppressing Alternaria fruit rot disease and promoting chili plant growth. The experiment was conducted at the Botanical Garden, Rajshahi University, Bangladesh from July 2006 to March 2007. Application of Trichoderma harzianum IMI 392432 significantly (p = 0.05) suppressed the disease compared to Alternaria tenuis (T2) treatment and improved both growth and yield. The treatment T4 (T. harzianum IMI-392432 + A. tenuis) was most effective in reducing disease percentage (72.27%) compared to A. tenuis (T1) treatment. The highest seed germination rate (85.56%) and the highest growth and yield (12.5 g/plant) was also recorded in the same treatment (T4), followed by T5 (T. harzianum IMI-392433 + A. tenuis), T6 (T. harzianum IMI-392434 + A. tenuis), T2 (T. virens IMI-392430 + A. tenuis), and T3 (T. pseudokoningii IMI-392431 + A. tenuis) treatment, while single treatment with A. tenuis significantly decreased these values.

항문생식기 헤르페스에 대한 한의학적 치료의 국내외 연구동향 분석 (A Review of the Effect of Korean Medicine on Genital Herpes)

  • 박연경;박치영
    • 대한한방부인과학회지
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    • 제31권1호
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    • pp.99-121
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    • 2018
  • Objectives: Genital herpes is common disease in gynecological field. Although various treatment options such as herbal medicine, acupuncture, moxibustion are used in genital herpes, there is not enough evidence about the treatment options. This study is to prove the efficacy of oriental medicine on genital herpes by investigating papers and suggest direction of future research. Method: We searched for papers which had both genital herpes and oriental medicine from Cochrane, Pubmed, Scopus, CNKI, Oasis, Korean traditional knowledge portal, Journal of Korean Obstetrics & Gynecology up to November 2017. After searching papers, we classified according to the study design and analyzed selected studies. Results: Sixteen papers were finally selected. Four papers are laboratory studies with Hartley guinea pig with recurrent genital herpes. Twelve papers are clinical trials which includes one single group trial, one controlled trial, ten randomized controlled trials. All of the studies have shown that herbal medicine is effective in improving the symptom of genital herpes and decreasing the recurrent rate of genital herpes and also has immunoregulatory effect. Conclusions: This study shows that herbal medicine could be a good treatment option for genital herpes. However, more well-designed clinical studies and laboratory studies will be needed.

Ginseng alleviates microbial infections of the respiratory tract: a review

  • Iqbal, Hamid;Rhee, Dong-kwon
    • Journal of Ginseng Research
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    • 제44권2호
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    • pp.194-204
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    • 2020
  • The detrimental impact of air pollution as a result of frequent exposure to fine particles posed a global public health risk mainly to the pulmonary disorders in pediatric and geriatric population. Here, we reviewed the current literature regarding the role of ginseng and/or its components as antimicrobials, especially against pathogens that cause respiratory infections in animal and in vitro models. Some of the possible mechanisms for ginseng-mediated viral inhibition suggested are improvements in systemic and mucosa-specific antibody responses, serum hemagglutinin inhibition, lymphocyte proliferation, cell survival rate, and viral clearance in the lungs. In addition, ginseng reduces the expression levels of proinflammatory cytokines (IFN-γ, TNF-α, IL-2, IL-4, IL-5, IL-6, IL-8) and chemokines produced by airway epithelial cells and macrophages, thus preventing weight loss. In case of bacterial infections, ginseng acts by alleviating inflammatory cytokine production, increasing survival rates, and activating phagocytes and natural killer cells. In addition, ginseng inhibits biofilm formation and induces the dispersion and dissolution of mature biofilms. Most clinical trials revealed that ginseng, at various dosages, is a safe and effective method of seasonal prophylaxis, relieving the symptoms and reducing the risk and duration of colds and flu. Taken together, these findings support the efficacy of ginseng as a therapeutic and prophylactic agent for respiratory infections.

Preparation of melamine-grafted graphene oxide and evaluation of its efficacy as a flame retardant additive for polypropylene

  • Monji, Parisa;Jahanmardi, Reza;Mehranpour, Milad
    • Carbon letters
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    • 제27권
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    • pp.81-89
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    • 2018
  • The present study aimed to prepare a novel efficient flame retardant additive for polypropylene. The new flame retardant was prepared by chemical grafting of melamine to graphene oxide with the aid of thionyl chloride. Fourier-transform infrared spectroscopy and thermogravimetric analysis proved that melamine had been successfully grafted to the graphene oxide. The modified graphene oxide was incorporated into polypropylene via solution mixing followed by anti-solvent precipitatio. Homogeneous distribution as well as exfoliation of the nanoplatelets in the polymer matrix was observed using transmission electron microscopy. Thermogravimetric analysis showed a significant improvement in the thermo-oxidative stability of the polymer after incorporating 2 wt% of the modified graphene oxide. The modified graphene oxide also enhanced the limiting oxygen index of the polymer. However, the amount of improvement was not enough for the polymer to be ranked as a self-extinguishing material. Cone calorimetry showed that incorporating 2 wt% of the modified graphene oxide lowered total heat release and the average production rate of carbon monoxide during burning of the polymer by as much as 40 and 35%, respectively. Hence, it was concluded that the new flame retardant can retard burning of the polymer efficiently and profoundly reduce suffocation risk of exposure to burning polymer byproducts.

Utilization of Bamboo Leaves as a New Resource of Natural Green Colorants

  • Shin, Younsook;Cho, Arang;Yoo, Dong Il
    • 한국염색가공학회지
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    • 제24권4호
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    • pp.247-252
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    • 2012
  • The objective of this study was to find an appropriate method and process for protecting the green color in bamboo leaves and subsequent extraction of the green colorants, chlorophyll. Various inorganic salts including cupric sulfate, ferric sulfate, and zinc chloride were employed as green color protectors. Accordingly, the effects of metal salts and treatment conditions on color protection were investigated to find appropriate protector and conditions. And also, the efficacy of bamboo colorants as a natural green dye was evaluated through dyeing and colorfastness tests. Antimicrobial activity of dyed fabrics was measured by shake flask method in terms of bacterial reduction rate using Staphylococcus aureus(ATCC 6538). On the basis of experimental results for stabilizing bamboo leaves colorants, it was confirmed that Cu was the most appropriate metal type considering dye uptake, photostability and light fastness, and its optimum concentration was 0.025%. After the stabilization, the colorants were extracted efficiently at NaOH aqueous solution of 1.00%. It was concluded that bamboo leave has a high potentiality as new resources to produce a natural green dye with antimicrobial functionality.

Ingestion Toxicity of Fipronil on Reticulitermes speratus kyushuensis (Isoptera: Rhinotermitidae) and Its Applicability as A Termite Bait

  • Kim, Si Hyun;Chung, Yong Jae
    • Journal of the Korean Wood Science and Technology
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    • 제45권2호
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    • pp.159-167
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    • 2017
  • Historical wooden buildings in Korea are being damaged by Reticulitermes speratus kyushuensis Morimoto, a type of subterranean termite, and the scale of this damage is increasing gradually because of global warming. This study evaluated the ingestion toxicity of the phenylpyrazole insecticide fipronil to R. s. kyushuensis and its applicability as termite bait with the aim of controlling termite colonies more efficiently. An ingestion toxicity assessment was conducted and the $LT_{50}$ was determined to be 4.43 day at concentrations of 10 ppm, indicating a slow-acting effect; therefore, 10 ppm was selected as an appropriate dose. A field applicability assessment was conducted in which the number of foraging workers and the rate at which the termites fed decreased 2 weeks after baiting, and termite colony activity was no longer apparent after 4 weeks demonstrating the efficacy of fipronil at eliminating colonies. Taken together, these results, indicate that low-dose fipronil eliminated R. s. kyushuensis colonies faster than insect growth regulators; therefore, it is expected to be useful when trying to conserve historical wooden buildings.

종양(腫瘍)의 전이(轉移) 및 재발(再發) 억제(抑制)에 관(關)한 고찰(考察) (A Study on the inhibition of metastasis and recurrence of neoplasm)

  • 김종대;조종관
    • 대한한방내과학회지
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    • 제18권2호
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    • pp.53-64
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    • 1997
  • Many types of cancer, current therapy other than surgery and/or radiotherapy was of only limited efficacy. At the basic chinese traditional medicine(TCM) there was increased understanding of the additional basic and clinical neoplasm treatment research. The metastasis and recurrence of neoplasm was the basis of yudu(餘毒) on remained neoplasm cell and stagnation of blood, thermotoxo, phlegm, asthenia of healthy enerngy, stagnation of vital energy. The principles therapy of neoplasm on metastasis and recurrence was based on knowledge of the method of support the healthy energy and strengthen the body resistance, promote blood circulation to remove blood stasis, clear away heat and toxic materials, dissipate phlegm and disperse the accumulation of evils, regulate vital energy and disperse the depressed vital energy. But the major clinical features of neoplasm was to be considered in developing a treatment plan include (1) distinguish between clinical and pathologic staging - acute and chronic, (2) classification of pathologic pattern, and (3) distinction of body situation : for examples asthenia - sthenia etc. It was most important to distinguish between supporting the healthy and eliminating the evil factors and to treat differently at the root and the branch cause of a neoplasm. This paper's results indicate that identification and effective use of TCM medicines inhibited netastasis and decreased recurrence and then we were able to expect increasing survival rate.

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생체전기임피던스 측정법에 의한 경신강지환16의 비만개선 효과 평가 (Clinical efficacy of Gyeongshingangjeehwan16 according to bioimpedence analysis system)

  • 정양삼;윤기현;최승배;윤미정;신순식
    • 동의신경정신과학회지
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    • 제19권1호
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    • pp.71-81
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    • 2008
  • Objective: Obesity threatens not only the problem of beauty but also health. Furthermore, it could be harmful a chronic disease to increase mortality rate. A purpose of this study is to show a effect of obesity control as developing a herbal medicine, Gyeongshingangjeehwan16 (GGEx16), in order to control obesity that is a harmful factor for healthy. Method : In order to prove the effect of GGEx16, BMI, fat distribution, fat control and fitness score which are closely related with obesity are considered as variables. Each variable is measured, for statistical analysis, using measurement implement of InBody 3.0 which applied a theory of bioimpedence analysis. Result and Conclusion : As a result of statistical analysis for four variables, it was improved that there are the improved effect for obesity because GGEx16 is statistically meaningful better than prior to taking.

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An advertisement method using inaudible sound of speaker

  • Chung, Myoungbeom
    • 한국컴퓨터정보학회논문지
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    • 제20권8호
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    • pp.7-13
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    • 2015
  • Recently, there are serviced user customized advertisement of various type using smart device. Representative services are advertisement service using light of smart TV screen or audible sound of smart TV to transmit advertisement information. However, those services have to do a specific action of smart device user for advertisement information or need audible audio information of TV contents. To overcome those weakness, therefore, we propose an advertisement method using inaudible sound of speaker based on smart device. This method supports the transfer of advertising content to the smart device user with no additional action or TV audio signal required to access that content. The proposed method used two high frequencies among 18kHz ~ 22kHz of audible frequency range which smart TV can send out. And it generates those frequencies synthesized with audio of TV contents as trigger signal which can send advertisements to smart device. Next, smart device analysis the trigger signal and request advertisement contents related to the signal to server. After then, smart device can show the downloaded contents to user. Because the proposed method uses the high frequencies of sound signals via the inner speaker of the smart device, its main advantage is that it does not affect the audio signal of TV content. To evaluate the efficacy of the proposed method, we developed an application to implement it and subsequently carried out an advertisement transmission experiment. The success rate of the transmission experiment was approximately 97%. Based on this result, we believe the proposed method will be a useful technique in introducing a customized user advertising service.