• Structural Engineering and Mechanics
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• v.16 no.2
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• pp.219-240
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• 2003

One of the most versatile approaches for analyzing the dynamic behavior of structural systems is direct time integration of semi-discrete equations of motion. However responses computed by time integration are generally inexact and hence the corresponding errors would rather be studied in advance. In spite of the various error estimation formulations that exist in the literature, it is accepted practice to repeat the analyses with smaller time steps, followed by a comparison between the results. In this paper, after a review of this simple method and disregarding the round-off errors, a more efficient, reliable and yet simple method for estimating errors and enhancing the accuracy is proposed. The main objectives of this research are more realistic error estimation based on the concept of convergence, approximately controlling the reliability by comparing the actual rate of convergence with the integration method's order of accuracy, and enhancement of reliability by applying Richardson's extrapolation. Starting from the errors at specific time instants, the study is then generalized to cases in which the errors should be estimated and decreased at specific events e.g. peak responses. Numerical study illustrates the efficacy of the proposed method.

• Parasites, Hosts and Diseases
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• v.39 no.4
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• pp.285-292
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• 2001

The present study aimed to evaluate control efficacy of clonorchiasis by two schemes of repeated treatment with praziquantel at two endemic villages in China. Residents of one village at Guangxi Autonomous Region were treated and examined 6-monthly and of another at Liaoning Province 12-monthly, In residents that took 25 mg/kg x3 (total 75 mg/kg) of Praziquantel every 6 months for one Year the e99 Positive rate showed a significant drop from 69.0% to 17.1%. In contrast, a group of same praziquantel medication once showed a slight marginal decrease in the egg rate from 18.9% to 12.2% after one year Of 39 subjects examined 3 times, 56.4% were cured, 7.7% persistently positive, one (2.6%) reinfected after cure or newly infected, but 25.6% were persistently negative. The present finding suggests that 6-monthly medication with 75 mg/kg of praziquantel should effectively lower the prevalence but incomplete for control of clonorchiasis in heavy endemic areas.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5169-5173
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• 2015

To determine the efficacy of postoperative adjuvant chemotherapy with paclitaxel plus cisplatin (Taxol + DDP, TP therapy) for stage IIA esophageal squamous cell carcinoma (ESCC) and to investigate the expression of RUNX3 in lymph node metastasis-negative esophageal cancer and its relationship with medical prognosis, a retrospective summary of clinical treatment of 143 cases of stage IIA esophageal squamous cell carcinoma patients was made. The patients were divided into two groups, a surgery alone control group (52 patients) and a chemotherapy group that received postoperative TP therapy (91 patients). The disease-free and 5 year survival rates were compared between the groups and a multivariate analysis of prognostic factors was performed. The same analysis was performed for cases classified as RUNX3 positive and negative, with post-operative specimens assessed by immunohistochemistry. Although the disease-free and 5 year survival rates in control and chemotherapy groups did not significantly differ and there was no significance in RUNX3 negative cases, postoperative adjuvant chemotherapy in the chemotherapy group was shown to improve disease-free and 5 year survival rate compared to the control group in RUNX3 positive cases. On Cox regression multivariate analysis, postoperative adjuvant chemotherapy (P<0.01) was an independent prognostic factor for RUNX3 positive cases, suggesting that postoperative TP may be effective as adjuvant chemotherapy for stage IIA esophageal cancer patients with RUNX3 positive lesions.

• Journal of Oriental Neuropsychiatry
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• v.24 no.2
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• pp.179-188
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• 2013

Objectives : The purpose of this study was to compare three therapies - auricular acupuncture, transdermal nicotine patch and therapy - in combination with auricular acupuncture and nicotine patch. Methods : The subjects of this study included 188 male smokers in their 20s, 30s, 40s and 50s, who visited Wonmi Public Health Center. They were evaluated with the Fagerstrom test for nicotine dependence, amounts of daily smoking and success rate of smoking cessation. The subjects decided on a therapy method strictly of their own choice. They were divided into three groups according to the therapy; auricular acupuncture group (62 persons), nicotine patch group (69 persons) and combination therapy group (57 persons). Results : All three groups resulted in statistically significant reducing effects of nicotine dependence and amounts of daily smoking. In the combination therapy group, nicotine dependence was significantly decreased by more than those of the other groups. There were no statistically significant differences in decrements of daily smoking and success rate of smoking cessation among the three groups. Conclusions : The above results suggest that auricular acupuncture and transdermal nicotine patch have significant effects of smoking cessation. If they are combined, it is expected that therapies for smoking cessation would be developed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.1
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• pp.113-120
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• 2008

Objective : The purpose of this study was to explore the correlation between efficacy and various factors of the acne patients. Method : We reviewed 30 acne patients who visited Allergy/Derma-cosmetic Clinic at Kyung Hee Neo Medical Center from June, 2006 to December, 2007 and were treated with herbal medicine and acupuncture for 4 weeks. We investigated premenstrual aggravation of acne, facial burning sensation, constipation, Heart Rate Variability(HRV) results and regional distribution of acne. And we evaluated inflammatory acnes according to the Korean Acne Grading System(KAGS). Results & Conclusions : 1. The average age of total patients was 23.0 years old. The most frequent age group was 21-25 years old. Patients evaluated as KAGS Grade 2 were most common. 2. In total patients, inflammatory acne were reduced significantly after 4 weeks of treatment. 3. The result of analysis on premenstrual aggravation of acne, facial burning sensation and constipation, there weren't any difference of treatment results on statistical meaning. 4. The results show that there were significant correlations between the Low Frequency at HRV and the rate of acne reduction. (Pearson correlation = -0.565) 5. If the distribution of acne did not involve the T-zone of the face, chest, or back of the body, inflammatory acne were significantly decreased after 4 weeks of treatment.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.43 no.2
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• pp.83-87
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• 2017

Objectives: The purpose of this study is to evaluate the treatment efficacy of enucleation after decompression. Materials and Methods: A total of 17 patients with cystic lesion of the jaw were treated with decompression followed by enucleation. Pre- and post-decompression panoramic radiographs were analyzed. Results: The mean percentage of reduction after decompression was 64%. The reaction was graded as good (>80%) in five patients (29.4%), moderate (50%-80%) in nine patients (52.9%), and poor (<50%) in three patients (17.6%). The reduction rate of larger cystic lesions was faster than that of smaller lesions. However, the reduction rate was not affected by age. The duration of follow-up ranged from one to eight years. There were no complications, and one case recurred. Conclusion: Decompression is an effective method for the initial treatment of jaw cysts.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.8
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• pp.1207-1211
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• 2015

Various laser systems have been widely used in almost all industrial technologies because they have high energy density, directivity and coherence. Recently the clinical application is becoming wider in medical parts such as incurable disease, diagnosis and so on. Generally, ruby laser beam has the greatest efficacy for removing tattoos, freckle and other skin problem. But current medical ruby laser system has the maximum repetition rate of 2Hz and optical output beam energy of 1J. Many medical doctors really want to have a high repetition ruby laser system because that can reduce the operation time. We investigated a new ruby laser system with high repetition rate of 4Hz using double cavities. Furthermore, we develop a new power supply system adopting zero voltage switching(ZVS) to minimize switching loss by LLC resonant converter designed as 2kW class.

• Journal of Korean Academy of Nursing
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• v.35 no.7
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• pp.1420-1425
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• 2005

Purpose: We try to disclose how much the keywords of the papers from the Journal of the Korean Academy of Nursing coincide with MeSH terminologies and to understand the major subjects of the recent nursing research in Korea from keywords. Methods: Keywords of journals were extracted and compared with MeSH terms. The frequency of the appearance of each keyword was sorted by a descending order. Results: Coincidence rate of 1,235 keywords with MeSH terms was $51.6\%$. Out of them, depression, elderly, stress, self efficacy, quality of life, exercise, middle-aged women, and women appeared most frequently in descending order. Conclusion: Coincidence rate of the keywords with MeSH terms was at an acceptable level, however to improve it, the education of submitters and editorial board members are required, as well as the copy editor, to take a role in checking keywords. To infer the subjects of the research from keywords might well represent the recent topics of research work.

• Smart Structures and Systems
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• v.4 no.6
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• pp.809-828
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• 2008

Real-time hybrid testing is an attractive method to evaluate the response of structures under earthquake loads. The method is a variation of the pseudodynamic testing technique in which the experiment is executed in real time, thus allowing investigation of structural systems with time-dependent components. Real-time hybrid testing is challenging because it requires performance of all calculations, application of displacements, and acquisition of measured forces, within a very small increment of time. Furthermore, unless appropriate compensation for time delays and actuator time lag is implemented, stability problems are likely to occur during the experiment. This paper presents an approach for real-time hybrid testing in which time delay/lag compensation is implemented using model-based response prediction. The efficacy of the proposed strategy is verified by conducting substructure real-time hybrid testing of a steel frame under earthquake loads. For the initial set of experiments, a specimen with linear-elastic behavior is used. Experimental results agree well with the analytical solution and show that the proposed approach and testing system are capable of achieving a time-scale expansion factor of one (i.e., real time). Additionally, the proposed method allows accurate testing of structures with larger frequencies than when using conventional time delay compensation methods, thus extending the capabilities of the real-time hybrid testing technique. The method is then used to test a structure with a rate-dependent energy dissipation device, a magnetorheological damper. Results show good agreement with the predicted responses, demonstrating the effectiveness of the method to test rate-dependent components.

• Journal of Embryo Transfer
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• v.22 no.4
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• pp.265-269
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• 2007

This study was conducted to investigate the efficacy of vitrification procedure for the cryopreservation of porcine oocytes and the utilization of vitrified oocytes as recipient cytoplasts for somatic cell nuclear transfer (NT), and observed that porcine oocytes are evaluated by pronuclear formation, and parthenogenetic development. Single fetal donor cells were deposited into the perivitelline space of vitrified enucleation oocytes, followed by electrical fusion and activation. NT embryos were cultured in NCSU-23 medium supplemented with 5% FBS, at $38.5^{\circ}C$ in 5% $CO_2$ and air. 1. When the developmental rates of the oocytes after being culture for $0{\sim}10$ hours vitrified with EDS and ETS were 42.0%, 38.0%, respectively. This results were lower than the control group(62.2%). 2. When the developmental rates of the oocytes after being culture for $0{\sim}10$ hours vitrified-thawed with sucrose and glucose, 5% PVP, NCSU-23 supplemented with 10% FBS were 33.3%, 25.9%, respectively. This results were lower than the control group(55.6%). 3. The fusion and development to the blastocyst stage between the NT embryos constructed with the vitrified and non-vitrified oocytes were significant differences. Developmental rate of oocytes and NT embryos constructed with the vitrified or non-vitrified oocytes were $13.0{\pm}2.4%\;and\;23.2{\pm}2.4%$, respectively.