• Journal of Pharmaceutical Investigation
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• 제38권5호
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• pp.319-323
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• 2008

For transdermal delivery of ceramides, various liposomes formulations were studied and evaluated. Sodium deoxycholate (SDC), Tween 20 and Span 85 were used as edge activators. The skin permeation of ceramides was performed using a Franz cell apparatus with hairless mouse skin. Among edge activators, SDC showed the higher values of deformability index and skin permeation than did others. For optimization of formulations, we varied the ratios of lipids to edge activators and the compositions between phosphatidylcholine (PC) and ceramides. The optimal ratio of lipid to SDC was observed to be 6:1 (w:w) and that of PC and ceramide was 1:1. Our results suggest that the skin permeation of ceramides could be enhanced by optimized deformable formulations of liposomes containing SDC as a major edge activator.

• Structural Engineering and Mechanics
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• 제61권2호
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• pp.255-266
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• 2017

In this study, self-supporting roofing elements especially convenient for large-span structures such as stadium, airport terminal, mall, coliseum, etc. were examined with respect to critical buckling load. These elements were assumed as laminated composite plates and, variation of free-edge forms, cutout types and lamination configurations were used as design parameters. Based on the architectural feature and structural requirements, the effects of curvilinear free-edge form on critical buckling load were focused on in this research. Within this scope, 14 types of lamination configuration were specified according to various orientation angle, number and thickness of plies with a constant value of total plate thickness. Besides that, 6 different types of cutout and 3 different free-edge forms were determined. By combining all these parameters 294 different critical buckling load analyses were performed by using ANSYS Mechanical software based on finite element method. Effects of those parameters on critical buckling load were evaluated referring to the obtained results. According to the results presented here, it may be concluded that lamination conditions have more significant influence on the critical buckling load values than the other parameters. On the other hand, it is perceived that curvilinear free-edge forms explicitly undergo changings depending on lamination conditions. For future work, existence of delamination might be considered and progression of the defect could be investigated by using non-linear analysis.

• 한국통신학회논문지
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• 제13권3호
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• pp.204-215
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• 1988

본 논문에서는 불규칙하게 변화하는 혼합 잡음이 부가되는 추적 계통의 상태 추정을 위한 적응 추정계통을 제안하였다. 유한수(N)의 이산벡터를 혼합 잡음의 존재 가능한 크기의 범위로 설정하기 위하여 binomial분포, edge분포, binomial-edge혼합 분포, Tchebyscheff분포, Tchebyscheff-edge 혼합 분포 등 불규칙 분포시켰으며, zero detector와 data selector로 구성된 feed forward path를 기존의 적응추정 계통에 삽입시킴으로써 정확한 추정이 가능하였다. 이산 벡터를 불규칙하게 분포시킴으로써 불규칙하게 변화하는 어떠한 크기의 혼합잡음에도 적응 추정이 중단되지 않고 효율적으로 진행되는 컴퓨터 시뮬레이션 결과를 얻었다.

• Wind and Structures
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• 제19권2호
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• pp.113-144
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• 2014

Separation bubble and conical vortices on a large-span flat roof were observed in this study through the use of flow visualization. The results indicated that separation bubble occurred when the flow was normal to the leading edge of the flat roof. Conical vortices that occur under the cornering flow were observed near the leading edge, and their appearance was influenced by the wind angle. When the wind changed from along the diagonal to deviating from the diagonal of the roof, the conical vortex close to the approaching flow changed from circular to be more oblong shaped. Based on the measured velocities in the conical vortices by flow visualization, a proposed two-dimensional vortex model was improved and validated by simplifying the velocity profile between the vortex and the potential flow region. Through measured velocities and parameters of vortices, the intensities of conical vortices and separation bubble on a large-span flat roof under different wind directions were provided. The quasi-steady theory was corrected by including the effect of vortices. With this improved two-dimensional vortex model and the corrected quasi-steady theory, the mean and peak suction beneath the cores of the conical vortices and separation bubble can be predicted, and these were verified by measured pressures on a larger-scale model of the flat roof.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.420-423
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• 2008

This present work is to find optimum design of a NACA65 axial fan blade with weighted average surrogate model. The numerical analysis by Reynolds-average Navier-Stokes equations with shear stress turbulence(SST) is discretized by finite volume approximations and solved on hexahedral grids for flow analysis. The blade aerodynamic shape is modified by six design variables for the optimization. The blade profile as well as stacking line is modified to enhance blade total efficiency. Six design variables, airfoil maximum camber, maximum camber location, leading edge radius, trailing edge radius, lean angle at 50% span and lean angle at 100% span, are selected for blade profile to enhance the total efficiency. The PBA model which is basically weighted average of the basis surrogates is used to find the optimal design in the design space from the constructed response surface model for the objective function. By the optimization, the total efficiency is increased by 1.4%.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2007년도 추계학술대회논문집
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• pp.326-331
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• 2007

This paper conducts a vibratory loads reduction analysis of an Advanced Active Trailing-edge Flap (AATF) blade utilizing single crystal piezoelectric actuators. For an AATF blade, a new L-L piezostack actuator using single crystal PMN-PT materials is designed. The AATF blade is designed to have similar characteristics to the Advanced Active Twist Rotor (AATR) blade. The active trailingedge flap is assumed to be 20% of the blade span and 15% of the chord, located at 75% of the blade radius. In order to conduct the vibratory loads reduction analysis of the AATF blade in forward flight, DYMORE, a multi-body dynamics analysis code, is used. The simulation result shows that the hub vibratory loads may be reduced by approximately 89% even with a much lower input-voltage when comparing with the other active rotor systems.

• 생물환경조절학회지
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• 제1권2호
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• pp.142-147
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• 1992

The wind pressure distributions were analyzed to provide fundamental criteria for the structural design on the two-span arched house according to the wind directions through the wind tunnel experiment. In order to investigate the wind force distributions, the variation of the wind force coefficients, the mean wind force coefficients, the drag force coefficients and the lift force coefficients were estimated using the experimental data. The results obtained are as follows : 1. The variation of the wind force with wind directions on the side walls was the greatest at the upwind edge of the walls. 2. The maximum negative wind force along the length of the roof appeared at the upwind edge at the wind direction of 60$^{\circ}$. 3. The maximum negative wind force along the width of the roof appeared at the width ratio and wind direction of 0$^{\circ}$ and 0.4 in the first house and 0.6 and 30$^{\circ}$ in the second house, respectively. 4. The mean negative wind force on the side walls of the first house at the wind direction of 0$^{\circ}$ was far greater than that of the second house, and the maximum negative wind force on the roof occurred at the wind direction of 30$^{\circ}$. 5. The maximum lift force appeared on the second house at the wind direction of 30$^{\circ}$, but the lift force on the first house was far greater than that on the second house at the wind direction of 0$^{\circ}$. 6. The parts to be considered for the local wind forces were the edges of the walls, and the edges of the x-direction and the width ratio, 0.4 of the y-direction in the roofs.

• 대한조선학회논문집
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• 제42권2호
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• pp.80-87
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• 2005

A set of experiments was carried out for obtaining the velocity field around the hydrofoil of finite span, using a wing of the NACA 0012 section in a circulating water channel. DPIV technique was used to measure the velocity field, and the velocity measurements along the span were done for 3 speeds, 3 submerged depths, and 4 angles of attack. Experimental data are compared with the theoretical assumptions, as well as the numerical findings by Lee and Lee(2004). Special care is given to the flow near the tips and in the region close to the leading edge. Though indirect, using the measured data of the velocity, it is now possible to compare the aerodynamic and the hydrodynamic strength of the circulation distribution of a wing in the framework of the lifting-line theory.

• International Journal of Korean Welding Society
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• 제5권1호
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• pp.29-34
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• 2005

Finite element analysis (FEA) and experimental studies on an elastic bending method have been performed in order to control the angular distortion at the fillet weldment for curved panel. Process parameters for the elastic bending method such as clamping span and release time were analyzed with reference to welding condition and geometric effect of the curved panel, which can minimize or prevent the angular distortion by producing a proper skin stress to the fillet weldment. The amounts of the angular distortion decrease almost in a linear manner with an increase in the skin stress. The skin stress required for non-angular distortion at the fillet weldment is strongly dependent on the plate thickness, not the heat intensity applied. The clamping span for obtaining uniform skin stress was defined as functions of the plate thickness and length of the free edge. Clamp should be removed after the fillet weldment is cooled down to room temperature for non-angular distortion. Effectiveness of the elastic bending method established was verified by its application to an actual curved panel.

• 한국산학기술학회논문지
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• 제20권5호
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• pp.569-576
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• 2019

PSC-Edge 거더 라멘교는 Edge 거더에 긴장력을 도입하고 정모멘트를 감소시켜 저형고와 장경간화가 가능한 교량이다. 본 교량은 가설벤트가 상부슬래브의 하부에 지지되고 Edge 거더부에 2차 강연선이 긴장된 후 거더 외측 면에 $45^{\circ}$방향의 사인장 균열이 발생하였다. 프리스트레스 정착부의 응력분포 및 파열균열의 양상에 관한 연구가 활발히 진행되었지만 기존 연구 결과는 본 구조물의 실제 형상과 경계조건이 상이하여 명백한 원인분석이 어려운 실정이다. 따라서 본 논문에서는 가설벤트의 경계조건을 추가로 고려된 3D Frame 해석을 수행하였으나 Edge 거더부에서 최대 압축응력이 발생하여 균열을 원인을 규명하기에는 한계가 있었다. 따라서 LUSAS 16.1을 사용한 3D Solid 해석을 수행하였으며 그 결과 Edge 거더의 하부와 상부슬래브의 경계부분에서 최대 주인장응력이 발생하였다. 최대 주인장응력과 방향여현을 사용하여 둔각부 Edge 거더 외측면의 소요 철근량을 분석한 결과 사용 철근량이 부족한 것으로 분석되었다. 따라서 추가 시공된 교량은 기존 교량보다 정착부의 철근량과 철근보강 범위를 확장시켰다. 그 결과 Edge 거더부의 균열은 더 이상 발생하지 않는 것으로 관찰되었다. 이와 유사한 PSC-Edge 거더 형식의 교량을 설계 및 시공할 때 본문에서 제안한 해석 및 보강방법을 적용하면 시공 중 발생하는 Edge 거더 외측면의 균열을 충분히 제어할 수 있을 것으로 기대된다.