Objectives A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers. A literature review, consisting of both domestic and international references, examined the chemical management system, working environment, level of exposure, and possible associated risks. This information may be utilized in the future to determine appropriate exposure levels in working environments. Methods Hazard assessment was performed using chemical hazard information obtained from international agencies, such as Organization for Economic Cooperation and Development-generated Screening Information Data Set and International Program on Chemical Safety. Information was obtained from surveys conducted by the Minister of Employment and Labor ("Survey on the work environment") and by the Ministry of Environment ("Survey on the circulation amount of chemicals"). Risk was determined according to exposure in workplaces and chemical hazard. Results In 229 workplaces over the country, 831 tons of DEHP have been used as plasticizers, insecticides, and ink solvent. Calculated 50% lethal dose values ranged from 14.2 to 50 g/kg, as determined via acute toxicity testing in rodents. Chronic carcinogenicity tests revealed cases of lung and liver degeneration, shrinkage of the testes, and liver cancer. The no-observed-adverse-effect level and the lowest-observed-adverse-effect level were determined to be 28.9 g/kg and 146.6 g/kg, respectively. The working environment assessment revealed the maximum exposure level to be $0.990mg/m^3$, as compared to the threshold exposure level of $5mg/m^3$. The relative risk of chronic toxicity and reproductive toxicity were 0.264 and 0.330, respectively, while the risk of carcinogenicity was 1.3, which is higher than the accepted safety value of one. Conclusions DEHP was identified as a carcinogen, and may be dangerous even at concentrations lower than the occupational exposure limit. Therefore, we suggest management of working environments, with exposure levels below $5mg/m^3$ and all workers utilizing local exhaust ventilation and respiratory protection when handling DEHP.
Scientists have long used conventional toxicological methods to establish 'safe levels of exposure' for chemicals presumed to have threshold health effects or doses below which significant effects are unlikely to occur. These same methods cannot be used to establish safe levels of exposure for non-threshold pollutants. such as carcinogens. Therefore. Federal regulatory agencies in the United States are using risk assessment methods to provide information for public health policy decisions concerning increases in risk associated with increases in exposure to carcinogenic and other non-threshold pollutants. Acceptable exposure/risk levels are decided by policymakers who consider descriptions and estimates of risks together with social and economic benefits from the uses of the chemical. 1bis paper focuses on the development of quantitative risk assessment approaches by Federal regulatory agencies in the United States, and identifies the mathematical models currently being used for risk extrapolation. including their inherent uncertainties. The uncertainties and limitations of these methods have led some scientists to question the utility of quantitative risk extrapolation. The experience of the; U.S. Environmental Protection Agency (EPA). as summarized in this paper. can provide a realistic basis for evaluating the pros and cons. Finally. shortcomings in current risk assessment methods and their use in policy decisions are explored. and areas for possible improvement. given current scientific knowledge. are identified.
Metal pollution of aquatic ecosystems is a problem of economic and health importance. Information regarding molecular responses to metal exposure is sorely needed in order to identify potential biomarkers. To determine the effects of heavy metals on chironomids, the full-length cDNA of alcohol dehydrogenase (ADH3) from Chironomus riparius was determined through molecular cloning and rapid amplification of cDNA ends (RACE). The expression of ADH3 was analyzed under various cadmium and copper concentrations. A comparative and phylogenetic study among different orders of insects and vertebrates was carried out through analysis of sequence databases. The complete cDNA sequence of the ADH3 gene was 1134 bp in length. The sequence of C. riparius ADH3 shows a low degree of amino acid identity (around 70%) with homologous sequences in other insects. After exposure of C. riparius to various concentrations of copper, ADH3 gene expression significantly decreased within 1 hour. The ADH3 gene expression was also suppressed in C. riparius after cadmium exposure for 24 hour. However, the effect of cadmium on ADH3 gene expression was transient in C. riparius. The results show that the suppression of ADH3 gene by copper exposure could be used as a possible biomarker in aquatic environmental monitoring and imply differential toxicity to copper and cadmium in C. riparius larvae.
Park, Sang June;Byon, Jihyang;Ban, Doo Hyun;Lee, Suhee;Sohn, Wook;Ahn, Seokyoung
Nuclear Engineering and Technology
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v.52
no.6
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pp.1231-1242
/
2020
The Kori Unit 1 will be decommissioned after a permanent shutdown in June 2017. South Korea has a 0.1 mSv/yr exposure limit standard for limited or unlimited site release. This is South Korea's first commercial NPP; therefore, if the containment building is reused as a memorial hall, it will contribute to the improvement of public understanding and enhance the public's acceptance of NPPs. Also, existing Kori Unit 1 nuclear power plant manpower resources can be reused after decommissioning and resident staff and memorial hall visitors can activate nearby commercial areas. Therefore, such a reuse scenario may also prevent an economic recession. The exposure dose was calculated using the following scenarios: worker in the containment building, visitor in the containment building, and worker in buildings other than the containment building. The exposure dose in the buildings was calculated by the RESRAD-BUILD developed by the Argonne National Laboratory (ANL). The preliminary exposure dose and derived concentration guideline level (DCGL) were derived.
Galvalume steel (GL) is widely used in marine and industrial environments. It is characterized by better corrosion resistance than carbon steel. However, corrosion and economic losses may occur as the usage time is increased. Therefore, in this study, an outdoor exposure test of GL for 36 months was conducted across six regions of Korea. Parameters such as corrosion rate, chrominance (color, chroma, and brightness), glossiness, and surface appearance were analyzed. The results showed no significant change in appearance, and the initial corrosion rate was large, but a tendency to decrease with time was observed. Increased outdoor exposure time led to increase in the level of corrosion products. In the case of coastal areas where S, Cl, and other elements were detected, a relatively high decrease in Zn content was observed. Al forms a protective oxide film and exists in the coating layer, but Zn dissolves due to its chemical activity and low potential.
The main objectives of the present study were to understand the knowledge and practice of breastfeeding mothers about the feeding and supplementary food and to analyze the factors related to it. The data for the present study collected from July 9 to July 31, 1984 for 302 mothers in Seoul. 1. The Knowledge of Breastfeeding Mothers about the Fee4ing and Supplementary Food (1) In the knowledge of mothers on the appropriate feeding pattern before 6 month, 69.3% of total women believed that breast-fed babies are healthier. There was a singificant difference in the type of feeding in order to education level, socio-economic state, and. mass-media exposure. (2) In the knowledge of mothers on an appropriate duration of lactation, the mean duration of breastfeeding is 8. 1 month. The duration of breastfeeding gradually decreases in order of education level, socio-economic state, mass-media exposure, and employment status. (3) In the knowledge of mothers on an appropriate time of introduction of supplementary food, the mean time of introduction of supplementary food is 4. 7 month. It is gradually decrease in order of education level, socioeconomic state, mass-media exposure, and employment state. 2. The Practice of Breastfeeding Mothers about the Feeding and Supplementary Food (1) The practice of mothers on infant-feeding before 6 month and that education level, socio-economic state and mass media exposure are the higher, the rate of breast feeding is the less. (2) The mean duration of breastfeeding is 9 month. It is 1 month longer the knowledge of mothers on an appropriate feeding pattern before 6 month. (3) The time of introduction of supplementary food is average 4.75 month. It is similar to the knowledge of mothers on an appropriate time about introduction of supplementary food. The result of this study indicate that the knowledge and practice of breast feeding is maintained comparatively high in low educated group, whereas it is noticeably decreasing among the high educated group. High educated group believed that the short duration of breastfeeding better than long, and they practiced breastfeeding so short period. And high educated group also thought early introduction of supplementary food is good for the babies health. Consequently, in this study, for the most part, elite group is found to have rather wrong opinions and practice about infant nutrition. Therefore the accurate information of infant nutrition is must be encouraged to mothers.
The Journal of Asian Finance, Economics and Business
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v.7
no.10
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pp.885-896
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2020
The purpose of this study is to shed light on the driving motivations of contributing social word of mouth on social networking sites (sWOM) toward both tangible and intangible products. In order to develop a research model, this study adopts the motivation theory and TAM model. Data was collected from 904 members of the cosmetic and restaurant communities by using the snowball method. After assessing the validity of all constructs, the structural equation modeling (SEM) is used to test the proposed hypotheses. Results show that personal motivations (satisfaction, opinion leadership, self-enhancement, and economic incentives) and characteristics of sWOM (Perceived Usefulness and Ease of Use) have positive effect on exposure and engagement behaviors. Here are our specific findings, (1) customer satisfaction positively affects online interactions on SNSs such as Like or Sharing a content; (2) sWOM contribution behavior exists in two structures (Exposure and Engagement) and affects each other; (3) This study combines two groups of personal motivation and TAM to conceptualize a research model; and (4) The motivations of contributing sWOM between a specified service and product are rather similar. These findings help digital managers to understand consumers' behavioral contributions on SNSs and also provide interesting insights for marketers.
Journal of the Korean Society of Environmental Restoration Technology
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v.24
no.6
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pp.97-107
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2021
Abnormal climate caused by climate change causes enormous social and economic damage. And such damage and its impact may vary depending on the location and regional characteristics of the region and the social and economic conditions of local residents. Therefore, it is necessary to continuously monitor whether there are indicators that are weaker than other regions among the detailed indicators that constitute the risk, exposure and vulnerability of climate change risk. In this study, the concept of climate change risk was used for heatwave to determine regional inequality of climate change risk. In other words, it was judged that inequality in climate change risk occurred in regions with high risk but high exposure and low vulnerability compared to other regions. As a result of the analysis, it was found that 13 local governments in Korea experienced regional inequality in climate change risk. In order to resolve regional inequality in climate change risks, the current status of regional inequality in climate change should be checked based on the analysis proposed in this study, there is a need for an evaluation and monitoring system that can provide appropriate feedback on areas where inequality has occurred. This continuous evaluation and monitoring-based feedback system is expected to be of great help in resolving regional inequality in climate change risks.
This study investigates the impacts of long-term climate variability on household consumption in Indonesia, a country highly vulnerable to climate change. The analysis combines household survey data from nearly 5,998 families with satellite-derived weather data from NASA POWER spanning 30 years. We use the long-term variability in temperature and precipitation as a proxy for climate change. This study examines the impact of climate change which proceeds over the long term, unlike previous studies concerning one-off or short-term climate events. In addition, using satellite data enhances the accuracy of households' exposure to climate variability. The analysis finds that households in a village with higher temperature and precipitation variability significantly consume less food. This implies that households more exposed to climate change are at higher risk of malnutrition in developing countries. This study has a limitation that it cannot rule out the potential endogeneity of choosing a climate-vulnerable residential location due to economic poorness.
Ha, Mi-Na;Lee, Won-Jin;Lee, Seung-Min;Cheong, Hae-Kwan
Journal of Preventive Medicine and Public Health
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v.41
no.5
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pp.345-354
/
2008
Objectives : Our objective is to review and summarize the previous studies on the health effects of exposure to oil spills in order to make suggestions for mid- and long-term study plans regarding the health effects of the Hebei Spirit oil spill occured in Korea. Methods : We searched PubMed to systemically retrieve reports on the human health effects related to oil spill accidents. The papers' reference lists and reviews on the topic were searched as well. Results : We found 24 articles that examined seven oil spill accidents worldwide over the period from 1989 to August 2008, including the Exxon Valdes, Braer, Sea Empress, Erika, Nakhodka, Prestige and Tasman Spirit oil spills. Most of the studies applied cross-sectional and short-term follow-up study designs. The exposure level was measured by assessing the place of residence, using a questionnaire and environmental and personal monitoring. Studies on the acute or immediate health effects mainly focused on the subjective physical symptoms related to clean-up work or residential exposure. Late or mid-term follow-up studies were performed to investigate a range of health effects such as pulmonary function and endocrine, immunologic and genetic toxicity. The economic and social impact of the accidents resulted in the socio-psychological exposure and the psychosocial health effects. Conclusions : Studies of the health effects of exposure to oil spills should consider a range of health outcomes, including the physical and psychological effects, and the studies should be extended for a considerable period of time to study the long-term chronic health effects.
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