• Title/Summary/Keyword: early stimulation

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Effects of pH Early Postmortem on Meat Quality in Beef Longissimus

  • Hwang, I.H.;Tompson, J.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.8
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    • pp.1218-1223
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    • 2003
  • The effects of type (high and low voltages) and time (3, 40 and 60 min postmortem) of stimulation on drip loss and meat color at 24 h post-mortem were determined on M. longissimus dorsi of 38 crossbred steers and heifers. In addition, the effect of pH early postmortem (70 min postmortem) on the rate and extend of meat tenderization was examined. Either high or low voltage stimulation at 3 min showed a tendency for faster pH decline (p=0.052) and higher drip loss (p=0.08), and improved the color dimensions of L*, a* and b* (p<0.01), compared to stimulation at 40 min. This was equivalent to approximately one unit of an AUSMEAT color chip. On the other hand, although there were significant differences in pH decline between high voltage stimulation at 40 and 60 min, and between low voltage stimulation at 40 min and control sides, drip loss and meat color did not differ significantly (p>0.05). The results suggested that early application of stimulation, regardless of type of stimulation, improved overall meat color at 24 h postmortem through its effect on faster glycolysing rate. However, if the pH decline was moderate, the benefit of electrical stimulation on meat color was not apparent. An intermediate pH decline resulted in the lowest shear force. Due to differential ageing rates the optimum pH at 70 min postmortem increased with ageing time from 5.96, 6.07, 6.12 and 6.14 for 1, 3, 7 and 14 days postmortem, respectively. This implied that a small difference in the rate of pH decline was important, especially carcasses stimulated for very early postmortem, and the optimum rate of pH decline varied with intended ageing period. The study suggests that the beneficial or adverse effects of electrical stimulation on drip loss, meat color and tenderness is determined by the rate of pH decline, rather than by stimulation treatment and time of application per se.

Effects of Multipath Electrical Stimulation on the Functional Recovery of Early Stage Patients of Total Knee Arthroplasty

  • Lee, Min-Young;Shin, Young-Jun;Kim, Myoung-Kwon
    • Journal of the Korean Society of Physical Medicine
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    • v.13 no.1
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    • pp.107-119
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    • 2018
  • PURPOSE: This research was intended to investigate the influence to function recovery at the early stage after surgery, by conducting Multipath Electrical Simulation and isometric exercise treatment as early stage medical treatment method for Total knee arthroplasty patients. METHODS: The subject of 30 patients having Unilateral Total knee arthroplasty over age 65, Multipath Electrical Simulation and isometric exercise (experiment group I), Conventional Electrical Simulation and isometric exercise (experiment group II) and isometric exercise (control group). The intervention was performed in 5 times per a week and 60 minutes per a day during 4 weeks. We performed research by conducting Neuromuscular Electrical Stimulation and isometric exercise together and measured pain, range of motion, muscle strength and gait ability before and after intervention. RESULTS: The result showed therapeutic improvement in experiment group I, experiment group II and control group, but Multipath Electrical Simulation and isometric exercise showed significant improvement in function recovery of early stage compared to Conventional Electrical Simulation and isometric exercise, only isometric exercise. CONCLUSION: Based on research result, in order for early state function recovery of Total knee arthroplasty patients, when conducting neuromuscular electrical stimulation and isometric exercise together, especially when applying Multipath Electrical Stimulation, we could know that it showed more significant improvement to function recovery after surgery. Also, we suggest that Multipath Electrical Simulation may become a useful tool as a method for intervention and performing in various diseases for weakening of Quadriceps muscle.

Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

  • Jin, Seon Tak;Lee, Myung Ki;Ghang, Ju Young;Jeon, Seong Man
    • Journal of Korean Neurosurgical Society
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    • v.52 no.3
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    • pp.261-263
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    • 2012
  • The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical experience of bilateral GPi-DBS under general anesthesia by using microelectrode recording in a 7-year-old girl with early-onset DYT1 generalized dystonia. Excellent improvement of her dystonia without neurological complications was achieved. This case report demonstrates that GPi-DBS is an effective and safe method for the treatment of medically refractory early-onset DYT1 generalized dystonia in children.

The Effect of the Parent Variables, Home Environment Stimulation and Social Support on Poverty in Early Childhood (취학 전 빈곤아동에 대한 부모, 가정환경 자극, 사회적 지원의 영향력 탐색)

  • Kim, Jeong-Mee;Kwak, Keumjoo
    • Korean Journal of Child Studies
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    • v.28 no.4
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    • pp.305-317
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    • 2007
  • This study investigated the effect of maternal interactive styles, parenting stress, home environment stimulation and social support on poverty in early childhood. Participants consisted of 145 mothers and their children living in Seoul and Kyounggi Province. Data included videotaped observations of parent-child play and standardized measures of social support, parenting stress, home environment, and child development. Results of the t-test indicated significant differences among father's age and education, mother's age and education, and income over the variable of poverty. Regression analyses indicated that home environment stimulation was the strongest predictor of variance in children's development. Results from the regression analyse were supportive of the hypothesis that home environment moderates the impact of poverty on children's development.

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Roles for α1-adrenoceptors during contractions by electrical field stimulation in mouse vas deferens

  • Alsufyani, Hadeel A.;Docherty, James R.
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.6
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    • pp.525-532
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    • 2021
  • We have investigated the relative roles of α1-adrenoceptors and purinoceptors in contractions to low and high frequency stimulation of the mouse vas deferens, in terms of the time course of responses. In separate experiments, isometric contractile responses were obtained to 10 pulses at 1 Hz and 40 pulses at 10 Hz. Responses to 1 Hz stimulation consisted of a series of discrete peaks. The α1A-adrenoceptor antagonist RS100329 (10-9M-10-7M) significantly reduced the response to the first pulse, the α1D-adrenoceptor antagonist BMY7378 (10-7M-10-6M) significantly reduced the response to the first two pulses, and the non-selective α1-adrenoceptor antagonist prazosin (10-8M) reduced the response to the first 4 pulses at 1 Hz. Responses to 10 Hz stimulation consisted of an early peak response and a maintained plateau response. RS100329 significantly reduced the peak response but did not significantly affect the plateau response. Prazosin, significantly reduced both the peak and plateau responses. The α1A-adrenoceptor antagonist RS17053 in high concentrations reduced mainly the plateau response leaving a clear early peak response. The plateau response of contraction was almost abolished by the purinoceptor antagonist suramin. These results suggest that there is a relatively minor early α1D-adrenoceptor and a larger early α1A-adrenoceptor component to stimulationevoked contractions of mouse vas deferens, but the major α1-adrenoceptor component is revealed by prazosin to be α1B-adrenoceptor mediated. α1B-Adrenoceptor activation probably facilitates contractions mediated by other α1-adrenoceptors and by purinoceptors. These results suggest that combined non-selective α1-adrenoceptor blockade, particularly α1B-adrenoceptor blockade, in addition to P2X1-purinoceptor blockade is useful in reducing male fertility.

Effects of an Oral Stimulation Program on the Transition from Tube to Bottle Feeding in Premature Infants (미숙아에게 적용한 구강 자극 프로그램이 젖병 수유로의 이행에 미치는 효과)

  • Kim, Hee-Young;Bang, Kyung-Sook
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.18 no.2
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    • pp.160-167
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    • 2011
  • Purpose: The purpose of this study was to identify the effects of an oral stimulation program on premature infant's transition from tube feeding to bottle feeding, decrease in desaturation during feeding, and early discharge. Methods: This quasi-experimental study was performed in one neonatal intensive care unit (NICU) of an university hospital. The control group data (n=69) were obtained from June 2008 to May 2009, and the experimental group data (n=67), from June 2009 to May 2010. The oral stimulation program (OSP) was provided daily before feeding for the experimental group until transition to bottle feeding was completed. Results: The OSP group began bottle feeding earlier and were on complete bottle feeding earlier than control group. Discharge delay due to feeding desaturation was lower than for the control group. Conclusion: The results indicate that OSP for premature infants was helpful in transition from tube feeding to bottle feeding and early discharge and thus can contribute health and development in premature infants.

Early Postmortem Processing Conditions on Meat Quality of Hanwoo (Korean Native Cattle) Beef during Storage

  • Kim, B.C.;Rhee, M.S.;Ryu, Y.C.;Imm, J.Y.;Koh, K.C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.12
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    • pp.1763-1768
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    • 2001
  • The combined effects of low voltage electrical stimulation (ES) and early short-term temperature conditioning on meat quality of Hanwoo beef (Korean native cattle) during storage were investigated. Shear force was influenced by ES and aging. Combination of ES and the $30^{\circ}C$ conditioning resulted in higher myofibril fragmentation index and improved lightness. There was no substantial difference in drip loss among treatments but ES samples showed higher cooking loss than control. Negative effect on shelf-life was not found by early short-term high temperature conditioning. Therefore, the meat quality of Korean native cattle was effectively improved by the combination of ES and the $30^{\circ}C$ conditioning.

TRH Stimulation Tests Compared with $T_3$ Suppression Tests in Patients With Marginal Hyperthyroidism (경도(輕度) 갑상선기능항진증환자(甲狀腺機能亢進症患者)에서 TRH 자극시험(刺戟試驗)과 $T_3$ 억제시험(抑制試驗)과의 비교연구(比較硏究))

  • Choi, Sung-Jae;Koh, Chang-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.14 no.1
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    • pp.17-21
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    • 1980
  • TRH stimulation tests and $T_3$ suppression tests were done in 13 patients with clinically suspected mild or early hyperthyroidism who were all conventional thyroid function tests gave results within the accepted normal range. The results were as follows 1. 6 patients with normal $T_3$ suppression test revealed normal TRH stimulation test and could be easily diagnosed as euthyroidism. 2. 7 patients with abnormal $T_3$ suppression test exhibited no TSH response to TRH stimulation test and could be easily diagnosed as hyperthyroidism. The TRH stimulation test is a single, sensitive and reliable test of thyroid function and can well replace $T_3$ suppression test in the diagnosis of marginal hyperthyroidism.

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Is Early Spinal Cord Stimulation in Patients with Complex Regional Pain Syndrome Necessary? -A case report- (복합부위통증증후군 제I형 환자에서 조기 척수자극술이 필요한가? -증례보고-)

  • Min, Hyoung Ki;Han, Kyung Ream;Lee, Sang Eun;Kim, Kyoung Tae;Kim, Chan
    • The Korean Journal of Pain
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    • v.19 no.2
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    • pp.223-227
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    • 2006
  • Complex regional pain syndrome (CRPS) is clinically characterized by pain, abnormal regulation of blood flow and sweating, edema of skin and subcutaneous tissues, sensory and motor disturbances, and trophic changes of the skin. A 21-year-old man was suffering from pain and swelling in his right hand and forearm. His arm had been in splints for 3 weeks following an extension injury of the right fingers and wrist, with the pain having developed 2 weeks after the splinting. He was treated with various nerve blocks including continuous epidural infusion, thoracic sympathetic block and peripheral nerve blocks, and squeezing his edematous region under general anesthesia as well as intravenous lidocaine and ketamine infusions. However, all of the performed treatments had no effect on the patient's pain or hand swelling. As a next line therapy, spinal cord stimulation should be considered because of intractable severe pain and swelling to almost all other modalities of therapy. We therefore performed an early intervention of spinal cord stimulation for the patient with refractory CRPS type I 5 months after the onset of pain and have got an excellent result.