Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
권호 표지
DOI QR코드

DOI QR Code

Deep Brain Stimulation of the Globus Pallidus in a 7-Year-Old Girl with DYT1 Generalized Dystonia

  • Jin, Seon Tak (Department of Neurosurgery, Maryknoll Medical Center) ;
  • Lee, Myung Ki (Department of Neurosurgery, Maryknoll Medical Center) ;
  • Ghang, Ju Young (Department of Neurosurgery, Bongseng Memorial Hospital) ;
  • Jeon, Seong Man (Department of Neurosurgery, Bongseng Memorial Hospital)
  • Received : 2012.03.23
  • Accepted : 2012.08.29
  • Published : 2012.09.28
Download PDF
⟨ Previous Next ⟩

Abstract

The experience of pediatric deep brain stimulation (DBS) of the globus pallidus internus (GPi) in the treatment of early-onset DYT1 generalized dystonia is still limited. Here, we report the surgical experience of bilateral GPi-DBS under general anesthesia by using microelectrode recording in a 7-year-old girl with early-onset DYT1 generalized dystonia. Excellent improvement of her dystonia without neurological complications was achieved. This case report demonstrates that GPi-DBS is an effective and safe method for the treatment of medically refractory early-onset DYT1 generalized dystonia in children.

Keywords

References

  1. Alterman RL, Tagliati M : Deep brain stimulation for torsion dystonia in children. Childs Nerv Syst 23 : 1033-1040, 2007 https://doi.org/10.1007/s00381-007-0382-x
  2. Augood SJ, Penney JB Jr, Friberg IK, Breakefield XO, Young AB, Ozelius LJ, et al. : Expression of the early-onset torsion dystonia gene (DYT1) in human brain. Ann Neurol 43 : 669-673, 1998 https://doi.org/10.1002/ana.410430518
  3. Constantoyannis C, Berk C, Honey CR, Mendez I, Brownstone RM : Reducing hardware-related complications of deep brain stimulation. Can J Neurol Sci 32 : 194-200, 2005 https://doi.org/10.1017/S0317167100003966
  4. Coubes P, Cif L, El Fertit H, Hemm S, Vayssiere N, Serrat S, et al. : Electrical stimulation of the globus pallidus internus in patients with primary generalized dystonia : long-term results. J Neurosurg 101 : 189-194, 2004 https://doi.org/10.3171/jns.2004.101.2.0189
  5. Dekaban AS : Changes in brain weights during the span of human life : relation of brain weights to body heights and body weights. Ann Neurol 4 : 345-356, 1978 https://doi.org/10.1002/ana.410040410
  6. Gross RE, Mewes K, Ghani G : Anesthesia for movement disorder surgery in Bakay RA (ed) : Movement Disorder Surgery. The Essentials. New York : Stuttgart, 2008, pp70-82
  7. Isaias IU, Alterman RL, Tagliati M : Outcome predictors of pallidal stimulation in patients with primary dystonia : the role of disease duration. Brain 131 : 1895-1902, 2008 https://doi.org/10.1093/brain/awn120
  8. Jeong SG, Lee MK, Kang JY, Jun SM, Lee WH, Ghang CG : Pallidal deep brain stimulation in primary cervical dystonia with phasic type : clinical outcome and postoperative course. J Korean Neurosurg Soc 46 : 346-350, 2009 https://doi.org/10.3340/jkns.2009.46.4.346
  9. Marks WA, Honeycutt J, Acosta F, Reed M : Deep brain stimulation for pediatric movement disorders. Semin Pediatr Neurol 16 : 90-98, 2009 https://doi.org/10.1016/j.spen.2009.04.001
  10. Pinsker MO, Volkmann J, Falk D, Herzog J, Steigerwald F, Deuschl G, et al. : Deep brain stimulation of the internal globus pallidus in dystonia : target localisation under general anaesthesia. Acta Neurochir (Wien) 151 : 751-758, 2009 https://doi.org/10.1007/s00701-009-0375-5
  11. Vidailhet M, Vercueil L, Houeto JL, Krystkowiak P, Lagrange C, Yelnik J, et al. : Bilateral, pallidal, deep-brain stimulation in primary generalised dystonia : a prospective 3 year follow-up study. Lancet Neurol 6 : 223- 229, 2007 https://doi.org/10.1016/S1474-4422(07)70035-2
  12. Zorzi G, Marras C, Nardocci N, Franzini A, Chiapparini L, Maccagnano E, et al. : Stimulation of the globus pallidus internus for childhoodonset dystonia. Mov Disord 20 : 1194-1200, 2005 https://doi.org/10.1002/mds.20510

Cited by

  1. Deep brain stimulation in children and young adults with secondary dystonia: the Children's Hospital Los Angeles experience vol.35, pp.5, 2012, https://doi.org/10.3171/2013.8.focus13300
  2. Deep brain stimulation in pediatric dystonia: a systematic review vol.43, pp.3, 2012, https://doi.org/10.1007/s10143-018-1047-9