• The Journal of Korea Assosiation for Disability and Oral Health
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• v.7 no.1
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• pp.25-28
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• 2011

Autism is a developmental, neuropsychiatric disorder that begins in early childhood. A patient with autism seen in the dental office frequently may have many complications. Therefore, it may be needed to consider modified or alternative therapy for dental care of autistic patients. This is the case of a 16-year old boy who have autism. He came to the department of the pediatric dentistry, Yonsei University Dental Hospital, for evaluation and treatment of dentigerous cyst associated with impacted teeth(#33,34,35). Under daily hospitalization and general anesthesia, the cyst was enucleated with surgical extraction of #34 and autotransplantation of #33,35. And during the periodic dental followup, apexification of #33,35 was performed for periapical lesion and root maturity. At 2 year 6 months follow- up, now, bony healing was completed and there are some complications like external resorption of #33 and space loss of #34 area. Generally, the marsupialization has been widely recommended for treatment of dentigerous cyst. However, in this case, there is a little possibility of spontaneous eruption after marsupialization considering of patient's age, location and angulation of the impacted tooth, root maturity. And there is necessity to choose the treatment that has low recurrence risk and needs short-term follow-up for autism. Above all, poor oral hygiene and lack of cooperation for decompression treatment is a matter of primary consideration. Consequently, enucleation of the cyst was chosen for the final treatment plan in this case. It is important to consider the conditions that affect the eruption of a dentigerous cyst-associated tooth to predict the successful eruption and special health care needs of the patient when the treatment plan is settled.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.22 no.5
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• pp.342-350
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• 1989

Maturity and spawning of Crangon affinis were studied based on the histological observation. The samples were monthly collected in Nakdong estuary from June, 1988 to May, 1989. The gonad lies on the dorsal side of the thorax. The cavity in which it lies is located below heart and above hepatopancreas. Anterior part of ovary is fused roundly, and the posterior part shows a pair of tubule-like structure. Testis is bilaterally symmetrical; the anterior part shows convoluted tubule, and the posterior part consists of a pair of tubule. Seminal vesicle is connected and opened to the base of the fifth pereiopod. Gametogenesis of ovum and spermatozoon is being repeated in short period without seasonality, and it is formed simultaneously in the whole parts of germinal epithelium. Diameter of a ripe oocyte is ca. $430{\mu}m$. Spermatozoa is oval with distinct nucleoplasm. Reproductive cycle is performed in ca. 40 days. Crangon affinis spawns all year round except November. Incubation period of brooded eggs took $12\~14$ days before hatching in the aquarium at $21^{\circ}C\~24^{\circ}C\;and\;33\%_{\circ}$.

• The Korean Journal of Malacology
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• v.19 no.2
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• pp.153-153
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• 2003

Reproductive cycle with the ovarian developmental phases, first sexual maturity of the female venus clam, Cyclina sinensis, was investigated by a histological study, and the number of spawned eggs and spawning frequency by artificial spawning induction of the clams were estimated. Samples were collected from the intertidal zone of Simpo, Gimje city, Korea between January and December, 2001. The reproductive cycle of this species can be classified into five successive stages; early active (February to April), late active (March to June), ripe (May to August), spent (July to September), and spent and inactive (September to February). The spawning period was once a year between July and August, a spawning peak was seen in July and August. Percentages of first sexual maturity of female clams of 25.1-30.0 mm in shell length were 64.3%, and 100% for the clams > 40.1 mm. The number of the eggs released from each clam by spawning induction increased as the size of clam in terms of shell length increased. The mean number of the eggs released from the second induction of spawning was 76.87% of the number of the eggs released in the first spawning. Our data indicated that the interval of each spawning was estimated to be approximately 15-17 (average 16.5) days.

• Journal of Life Science
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• v.19 no.12
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• pp.1851-1854
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• 2009

This study correlated changes in the plasma levels of estradiol-$17{\beta}$ (E2) with changes in the gonadosomatic index (GSI) and ovarian development during the annual reproductive cycle of the pike eel Muraenesox cinereus, collected at the Tongyung coast region. Ovarian maturity was classified based on histological observations; the perinucleolus stage (November to February), the oil droplet stage (March to April), the early vitellogenic stage (April to May) and the late vitellogenic stage (June to October). Seasonal changes in the GSI were correlated with water temperature and reflected the degree of ovarian maturity. Plasma E2 levels were correlated with changes in the GSI, which increased from April to a peak in July, and the levels remained comparatively high until October. These data indicated that changes in the GSI and plasma E2 levels are correlated with the annual ovarian activity of the pike eel. In this study, however, female pike eels were not collected during the spawning stage. Therefore, spawning of this species seemed to be closely related to its migration toward the deep sea of offshore.

• Korean Journal of Organic Agriculture
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• v.21 no.3
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• pp.437-450
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• 2013

Miscanthus sacchariflorus var. No. 1 has been newly developed in Korea. This study was conducted to assess the feed value of M. sacchariflorus var. No. 1 at different growth and harvesting time. Total 3 different miscanthus - 1y4m (first shoot and harvested at 4 month), 2y4m (second shoot and harvested at 4 month) and 2y8m (second shoot and harvested at 8 month). Two experiments were carried out, In vitro rumen simulated fermentation and In situ dry matter digestibility (DMD). Ruminal pH at in vitro fermentation were higher in M. sacchariflorus var. No. 1 treatments compared to the rice straw (RS). In volatile fatty acid production, 1y4m resulted in higher acetate production than the other M. sacchariflorus var. No. 1 at higher maturity stages. Significant differences among treatments were observed in propionate and total volatile fatty acid (VFA) productions at 9, 24 and 48 h of incubation times. Higher ammonia nitrogen productions were found as increased maturity of M. sacchariflorus var. No. 1. At In situ experiment, high DMD was detected in the order of RS (60.51%) > 1y4m (57.65%) > 2y4m (57.63%) > 2y8m (46.28%). The results from this study indicate that young and early harvested M. sacchariflorus var. No. 1 are able to improve its nutrient values in the ruminant animal.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.50 no.6
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• pp.378-383
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• 2005

This study was conducted in order to exam­ine relationships between the viviparous germination ability and the antioxidative system in rice seeds and seedlings. Enzyme activities was compared among the four varieties with different viviparous germination ability from the early or mid-late maturity group. $\alpha$-Amylase activities correlated with the viviparous germination rate (VGRs) and $\alpha$-amylase activity in seeds of 40 days after heading (DAH) was highest in Dongjinbyeo among mid­late maturing varieties (MLMVs) and in Daeseongbyeo among EMVs. $\alpha$-Amylase activity in dry mature seeds was also higher in varieties with higher VGR. Glucose contents in viviparously germinating seeds and mature dry, seeds were higher in varieties with higher VGRs. Cat-alase activities did not correlate with the VGRs in both maturity groups. However, peroxidase activities in viviparously germinating seeds were higher in varieties with higher VGRs.

• The Korean Journal of Malacology
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• v.20 no.1
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• pp.75-84
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• 2004

Reproductive cycle, the condition index, sex ratio of the Pacific oysters, Crassostrea gigas were investigated by histological and morphometric data. The specimens were collected in the two oyster farms of Geoje and Namhae, Gyeongsangnam-do, Korea, from November 1995 to October 1996. Growth of shell length in two regions was similar, but growth of total weight of the oyster in Namhae was faster than that in Geoje oyster farm. The spawning periods in female and male clams were from July to October in Geoje and from June to October in Namhae oyster farm. Ripe oocytes were approximately 50 m in diameter. The reproductive cycle of in females and males in Geoje and Namhae oyster farms can be divided into five successive stages: early developing, late developing, ripe, partially spawned and spent/inactive. Monthly changes in gonad developmental phases showed somewhat different patterns between female and male clams except for the spawning period. On the whole, however, monthly changes in the gonad developmental phases showed a similar pattern in the same sex. The sex ratios of females to males in Geoje and Namhae oyster farms were not significantly different from a 1:1 sex ratio ($x^2$ = 0.55 (p > 0.05) in Geoje and $x^2$ = 0.27 ( p > 0.05) in Namhae). Artificial induction of maturation by heating of adult oysters (two-year-old) was investigated from 17 January to 18 March in 1996. Maturity at the fixed water temperature group of $20^{\circ}C$ was 80%, it showed the highest maturity of experimental groups cultured for five weeks. The survival (%) of Crassostrea gigas in the raised water temperature experimental groups (15, 20, $25^{\circ}C$) were over 98.5%, as similar to the control group (100%). But, the survival of C. gigas in the fixed water temperature experimental groups (15, 20, 25, $30^{\circ}C$) were decreased with the increase of the water temperatures. In the fixed water temperature experimental group of $30^{\circ}C$, the survival was 51.1%. Base on these results, the fixed water temperature of $20^{\circ}C$ was the best condition for artificial induction of sexual maturation.

• Genomics & Informatics
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• v.12 no.4
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• pp.240-246
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• 2014

Mutation in HNF1B, the hepatocyte nuclear factor-$1{\beta}$ (HNF-$1{\beta}$) gene, results in maturity-onset diabetes of the young (MODY) 5, which is characterized by gradual impairment of insulin secretion. However, the functional role of HNF-$1{\beta}$ in insulin secretion and glucose metabolism is not fully understood. We identified a family with early-onset diabetes that fulfilled the criteria of MODY. Sanger sequencing revealed that a heterozygous P159L (CCT to CTT in codon 159 in the DNA-binding domain) mutation in HNF1B was segregated according to the affected status. To investigate the functional consequences of this HNF1B mutation, we generated a P159L HNF1B construct. The wild-type and mutant HNF1B constructs were transfected into COS-7 cells in the presence of the promoter sequence of human glucose transporter type 2 (GLUT2). The luciferase reporter assay revealed that P159L HNF1B had decreased transcriptional activity compared to wild-type (p < 0.05). Electrophoretic mobility shift assay showed reduced DNA binding activity of P159L HNF1B. In the MIN6 pancreatic ${\beta}$-cell line, overexpression of the P159L mutant was significantly associated with decreased mRNA levels of GLUT2 compared to wild-type (p < 0.05). However, INS expression was not different between the wild-type and mutant HNF1B constructs. These findings suggests that the impaired insulin secretion in this family with the P159L HNF1B mutation may be related to altered GLUT2 expression in ${\beta}$-cells rather than decreased insulin gene expression. In conclusion, we have identified a Korean family with an HNF1B mutation and characterized its effect on the pathogenesis of diabetes.

• The korean journal of orthodontics
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• v.32 no.5 s.94
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• pp.301-312
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• 2002

Treatment timing is a very important factor to consider in treating skeletal Class III patients by means of maxillary protraction. According to the literature maxillary Protraction should be carried out at an early age before puberty. However, no scientific data were presented to support this statement and recent studies supported by statistical data showed disagreement concerning the optimum treatment time of maxillary protraction. Therefore, there is no agreement about the optimum treatment time of maxillary protraction. In this study hand-wrist X-rays were taken from 119 patients and subjects were grouped into prepubertal and pubertal group according to their skeletal maturity. Pretreatment and posttreatment lateral cephalometric X-rays were taken and treatment effects were compared. The average treatment time was 6.5 months for the prepubertal group and 6.1 months for the pubertal group. The obtained results were as follows ; 1. The amount of maxillary forward movement was the same for Pretreatment and pubertal group. 2. The amount of maxillary downward movement was the same for prepubertal and pubertal group. 3. The amount of mandibular downward and backward rotational movement was the same for prepubertal and pubertal group. 4. Dental effects were the same for prepubertal and pubertal group.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.28 no.2
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• pp.173-183
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• 1983

To evaluate growing degree days(GDD) as an index of growth duration of rice plants, 30 days old seedlings of 16 japonica and 14 indica/japonica varieties were transplanted six times from May 10 at the 10-day intervals at Gyeongsan in 1982. The number of days from transplanting to heading decreased as transplanting dates delayed in all japonica varietie and 4 indica/japonica varieties but that of 10 indica/japonica varieties decreased up to June 9 or June 19 transplantings and then it levelled off or increased with further delay of transplanting. However, GDD requirement was similar among transplanting dates at appropriate base temperatures; GDD could be better than calendar day system to classify maturity of varieties especially grown in a wide range of climatic conditions. Required GDD from transplanting to heading of all indica/japonica and early japonica varieties showened a smaller coefficient of variation (CV) compared to longer season japonica varieties. Among GDD methods, an accumulation of daily Max + Min temp./2 -$l0^{\circ}C$ showed the smallest CV for the duration from transplanting to heading, but for ripening period GDD calculated with adjusted maximum temperature when it was higher than $30^{\circ}C$ showed the best results. Heading date did not affect required GDD for maturity of japonica varieties, but in indica/japonica varieties GDD decreased as heading date delayed; at late transplantings ripening period of indica/japonica varieties was less extended compared to japonica varietes due to a decrease in grain weight.