• 대한수의학회지
• /
• 제40권1호
• /
• pp.145-152
• /
• 2000

This study was performed to study the sequential clinical and pathologic changes of Korean isolate KBA-2 of Neospora caninum in SCID mice following intraperitoneal infection. Also the results of PCR and in vitro isolation was compared during the study. The infection appears to be disseminated hematogenously, when the infection was chased every 3days up to 21 days following infection. The PCR method was determined to be more effective than in vitro isolation regarding early detection of the organism follwing infection.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제32권2호
• /
• pp.168-173
• /
• 2006

The side effects of head and neck radiation therapy include mucositis, xerostomia, loss of taste, radiation caries, oral infection, osteoradionecrosis and trismus. When a patient is arranged to begin head & neck radiotherapy, oral pathologic lesions are examined and managed for the prevention of oral complications. The advanced odontogenic infection should be especially controlled before the radiotherapy and the patient must be instructed for proper oral prophylaxis. Generally the more conservative treatments, such as, scaling, restoration, endodontic treatment, are the care of choice and dental extraction is performed in advanced periapical and periodontal pathologic conditions. If the dental extraction should be done, the radiotherapy consequently will be delayed until there is epithelium covering the extraction socket, leaving no exposed bone. The cancer patient with severe emotional stress pray for the early radiation therapy, in spite of possibility of the recurrent odontogenic infectious lesions. So, the authors attempted to do the early radiation therapy by the conservative endodontic drainage and surgical incision & drainage without extraction of the infected teeth, and resulted in relatively good prognosis without the severe side effects of head and neck radiotherapy.

• Clinical and Experimental Pediatrics
• /
• 제62권1호
• /
• pp.36-41
• /
• 2019

Purpose: In this study, we investigated the clinical features and prognostic factors of early-onset sepsis (EOS) in neonatal intensive care unit (NICU) patients. Methods: A retrospective analysis was conducted on medical records from January 2010 to June 2017 (7.5 years) of a university hospital NICU. Results: There were 45 cases of EOS (1.2%) in 3,862 infants. The most common pathogen responsible for EOS was group B Streptococcus (GBS), implicated in 10 cases (22.2%), followed by Escherichia coli, implicated in 9 cases (20%). The frequency of gram-positive sepsis was higher in term than in preterm infants, whereas the rate of gram-negative infection was higher in preterm than in term infants (P<0.05). The overall mortality was 37.8% (17 of 45), and 47% of deaths occurred within the first 3 days of infection. There were significant differences in terms of gestational age (26.8 weeks vs. 35.1 weeks) and birth weight (957 g vs. 2,520 g) between the death and survival groups. After adjustments based on the difference in gestational age and birth weight between the 2 groups, gram-negative pathogens (odds ratio [OR], 42; 95% confidence interval [CI], 1.4-1,281.8) and some clinical findings, such as neutropenia (OR, 46; 95% CI, 1.3-1,628.7) and decreased activity (OR, 34; 95% CI, 1.8-633.4), were found to be associated with fatality. Conclusion: The common pathogens found to be responsible for EOS in NICU patients are GBS and E. coli. Gram-negative bacterial infections, decreased activity in the early phase of infection, and neutropenia were associated with poor outcomes.

• Parasites, Hosts and Diseases
• /
• 제54권4호
• /
• pp.519-525
• /
• 2016

To investigate the potential role of transforming growth factor (TGF)-${\beta}1$ in liver fibrosis during Echinococcus granulosus infection, 96 BALB/c mice were randomly divided into 2 groups, experimental group infected by intraperitoneal injection with a metacestode suspension and control group given sterile physiological saline. The liver and blood samples were collected at days 2, 8, 30, 90, 180, and 270 post infection (PI), and the expression of TGF-${\beta}1$ mRNA and protein was determined by real-time quantitative RT-PCR and ELISA, respectively. We also evaluated the pathological changes in the liver during the infection using hematoxylin and eosin (H-E) and Masson staining of the liver sections. Pathological analysis of H-E stained infected liver sections revealed liver cell edema, bile duct proliferation, and structural damages of the liver as evidenced by not clearly visible lobular architecture of the infected liver, degeneration of liver cell vacuoles, and infiltration of lymphocytes at late stages of infection. The liver tissue sections from control mice remained normal. Masson staining showed worsening of liver fibrosis at the end stages of the infection. The levels of TGF-${\beta}1$ did not show significant changes at the early stages of infection, but there were significant increases in the levels of TGF-${\beta}1$ at the middle and late stages of infection (P<0.05). RT-PCR results showed that, when compared with the control group, TGF-${\beta}1$ mRNA was low and comparable with that in control mice at the early stages of infection, and that it was significantly increased at day 30 PI and remained at high levels until day 270 PI (P<0.05). The results of this study suggested that increased expression of TGF-${\beta}1$ during E. granulosus infection may play a significant role in liver fibrosis associated with E. granulosus infection.

• 식물병연구
• /
• 제9권2호
• /
• pp.68-71
• /
• 2003

이삭도열병 발병시기가 빠를수록 벼 수량은 비례하여 감소되는데 조생종인 진미벼의 경우 출수 초기에 발병된 벼는 2년간의 조사결과 83.9%와 81.6%가 각각 감수되었으며, 출수 30일과 42일 후에 발병될 경우에도 44.3%와 33.1%가 감수되었다. 이삭도열병 발생식기가 벼 수량에 미치는 영향을 추정하기 위하여 회귀 분석을 한 결과, 1999년은 y =-1.9729x + 71.878($R^2$ = 0.9764), 2000년은 y = ?1.6421x + 97.212($R^2$ = 0.8569)로 발병시기와 수량감소와는 매우 높은 부의 상관관계가 있었다. 중만생종인 추청벼의 경우에도 2년간의 조사결과 출수 초기에 발병된 벼는 64.9%와 47.8%가 감수되었으며, 출수 40일 후 발병된 경우 29.1%와 8.9%가 감수되었으며, 1999년은 y =-1-.2717x + 79.523($R^2$ = 0.9487), 2000년은 y = ?1.6872x + 74.545($R^2$ = 0.7993)로 발병시기와 수량감소와는 매우 높은 부의 상관관계가 있었다. 천립중 조사결과도 출수초기에 발별된 경우 백수가 많았으며, 건전구 대비 진미벼는 38.3%, 추청벼는 57.3% 정도였으며, 출수 40일 후 발병된 경우 건전구 대비 진미벼는 87.9%, 추청벼는 92.9%로 천립중이 가벼워 벼가 충실하게 성숙되지 않음을 알 수 있었다.

• 한국작물학회지
• /
• 제40권1호
• /
• pp.44-51
• /
• 1995

도입에 의존하고 있는 풋콩 종자 생산체계를 확립하고자 조숙성 품종인 큰올콩과 풋콩 도입풍종인 Fukura 피두를 평야지（영남농업시험장） 및 고랭지（경남 밀양군, 사자평 ：해발 850m）에 파종시기（5월 15일, 6월 15일, 7월 15일）를 달리하여 생육 및 수량과 병해립 및 저장후 발아력을 조사한 결과를 요약하면 다음과 같다. 1. 파종시기가 빠를수록 협수가 많고 100립종은 무거웠으며 수량도 높았다. 재배지별로는 평야지가 고랭지보다 증수되었고, 큰올콩이 Fukura보다 수량성이 높았다. 2. 남부지방의 산간 고랭지는 평야지에 비해 생육 및 100립종이 저하하고 수량성이 크게 떨어져 평야지보다 불리하였다. 3. 안전립 수량은 파종시기가 빠를수록 높고, 평야지 및 큰올콩품종에서 증수되었으며, 전체 립종에 대한 안전립 비율은 고랭지에서 높게 나타났다. 4. 파종시기에 따른 병해정도는 큰올콩은 뚜렷한 차이가 없었으나 Fukura는 파종기가 빠를수록 나병립율이 높았고, 미이라병은 파종기가 빠를수록 심하게 발생하였으며 자정병은 파종기가 늦을수록 많이 발생하는 경향이었다. 5. 종자의 발아율은 파종기가 늦은 것이 높았으며, 5월 15일에 파종하여 수확ㆍ저장한 종자의 발아율은 매우 낮아 문제시 되었다. 따라서 풋콩 종자생육을 위한 적정파종시기는 수파기의 고온ㆍ다습한 환경을 고려하여 6월 중순경이 좋을것으로 생각되었다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권3호
• /
• pp.879-883
• /
• 2012

Cervical cancer is caused by HPV infection and can be prevented by early vaccination. Objective: To assess Syrian women's level of knowledge and determinants of good knowledge of cervical cancer, HPV infection and its vaccines. Methods: A cross sectional survey was undertaken among mothers with daughters in sixth grade classes enrolled in primary schools in Aleppo city, Syria. Samples were selected through cluster sampling and data collected using a self-administered questionnaire. Results: Less than a third of the mothers had heard of HPV infection and vaccines against cervical cancer and levels of knowledge were generally low. Good knowledge was associated with high education level, higher family monthly income, having few - less than four children, positive history of cervical cancer screening, and working or having relatives working in the medical field. The main source of information was television and few reported health care providers as a source of knowledge on HPV infection and vaccine. Conclusion: Since knowledge of HPV infection and its connection with cervical cancer and its vaccine are low, more efforts must be made to educate Syrians prior to introduction of any HPV vaccination programme. Public health efforts must focus on educating mothers, the public as well as health care providers.

• Clinical and Experimental Pediatrics
• /
• 제50권7호
• /
• pp.698-701
• /
• 2007

Cryseobacterium meningosepticum은 흙, 병원, 수돗물을 포함한 물이 있는 환경에서 발견되는 그람 음성 막대균으로, 미숙아, 노인과 같이 면역성이 결여된 인체에 기회감염을 일으키고, 미숙아에서는 패혈증, 뇌수막염과 같은 중증 질환을 유발하여 사망률과 합병증 발생이 높다. 특히, 균주가 병원내 배수관, 기계장비등을 통해 오염되어 신생아실에서 폭발적 유행이 가능하다. 저자들은 미숙아에서 발생한 다항생제 내성 C. meningosepticum에 의한 패혈증, 뇌수막염을 ciprofloxacin으로 치료한 1례와 동기간에 무증상 보균상태를 보였던 1례와 성공적인 환경검사와 조절에 대해서 보고하는 바이다.

• Archives of Plastic Surgery
• /
• 제42권1호
• /
• pp.68-72
• /
• 2015

For recent years, use of autologous fat injection has increased significantly in facial contouring surgery. Along with such increase in use, complications like atypical mycoplasma infection have been also on the increasing trend. The authors report two cases of Mycobacterium chelonae infection that occurred after autologous fat injection. Patients were treated as infection that resistant to common antibiotics and results were negative to routine culture and Gram staining. Acid-fast bacillus stain, polymerase chain reaction (PCR) test and mycobacterial cultures were conducted for diagnosis under suspicion of atypical mycoplasma infection. Then, combination antibiotics therapy, surgical treatment, and steroid injection were performed for treatment. Both patients were diagnosed with Mycobacterium chelonae in PCR test. They were positive to mycobacterial cultures. Combination antibiotics therapy was repeated to improvement of symptom. However, they could not be free from side effects such as deformation in facial contour, scar and pigmentation even after full recovery. When chronic wound infections after autologous fat injection, we must suspect atypical or mycobacterial infection and conduct examinations for a early diagnosis and proper antibiotic therapy that is effective to the nontuberculous mycobacteria.

• 동서간호학연구지
• /
• 제28권1호
• /
• pp.21-30
• /
• 2022

Purpose: This research aimed to assess nursing students' knowledge, attitudes and infection prevention behaviors toward the coronavirus disease-19 (COVID-19). Methods: A cross-sectional survey was conducted from September 11 through October 1, 2020, involving a total of 235 third and fourth year of nursing students enrolled in two universities in U and K city. Self-report questionnaires consisting of demographic characteristics, knowledge, attitudes and infection prevention behaviors toward the COVID-19 were administered to the participants. Results: Influencing factors for infection prevention behaviors were gender (β=0.21, p<.001), attitudes toward infection control (β=0.38, p<.001), education experience regarding COVID-19 (β=0.21, p=.004), and a visit to the hospitals or the areas where the COVID-19 case has occurred or been admitted (β=-0.18, p=.003) which explained 23.6% of the total variance. Conclusion: The results of this study provides basic information regarding nursing students' knowledge about COVID-19, attitudes toward infection control, and infection prevention behaviors during the initial outbreak of COVID-19.